Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
29942
Gene name Gene Name - the full gene name approved by the HGNC.
Purine rich element binding protein G
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
PURG
Synonyms (NCBI Gene) Gene synonyms aliases
PURG-A, PURG-B, PURGA, PURGB
Chromosome Chromosome number
8
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
8p12
Summary Summary of gene provided in NCBI Entrez Gene.
The exact function of this gene is not known, however, its encoded product is highly similar to purine-rich element binding protein A. The latter is a DNA-binding protein which binds preferentially to the single strand of the purine-rich element termed PU
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT020365 hsa-miR-29c-3p Sequencing 20371350
MIRT510901 hsa-miR-186-5p HITS-CLIP 21572407
MIRT506002 hsa-miR-6507-5p HITS-CLIP 21572407
MIRT510900 hsa-miR-1277-5p HITS-CLIP 21572407
MIRT521555 hsa-miR-4789-3p HITS-CLIP 21572407
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000977 Function RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA 21873635
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA 21873635
GO:0003723 Function RNA binding HDA 22681889
GO:0005634 Component Nucleus IBA 21873635
GO:0006357 Process Regulation of transcription by RNA polymerase II IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
618041 17930 ENSG00000172733
Protein
UniProt ID Q9UJV8
Protein name Purine-rich element-binding protein gamma (Purine-rich element-binding protein G)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04845 PurA 57 321 PurA ssDNA and RNA-binding protein Family
Tissue specificity TISSUE SPECIFICITY: Isoform 1 is expressed in testis and glioblastoma. Isoform 2 is expressed in fetal lung. {ECO:0000269|PubMed:12034829}.
Sequence
Sequence length 347
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Breast cancer Malignant neoplasm of breast rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158
View all (309 more)
Diabetes mellitus Diabetes Mellitus, Non-Insulin-Dependent rs587776515, rs61730328, rs606231121, rs606231122, rs79020217, rs77625743, rs78378398, rs606231123, rs1362648752, rs104893649, rs80356624, rs80356616, rs80356625, rs80356611, rs104894237
View all (293 more)
30054458
Unknown
Disease term Disease name Evidence References Source
Metabolic Syndrome Metabolic Syndrome GWAS
Diabetes Diabetes GWAS
Hypertension Hypertension GWAS
Insomnia Insomnia GWAS
Associations from Text Mining
Disease Name Relationship Type References
Neoplasms Associate 12034829
Werner Syndrome Associate 12034829