PURG (purine rich element binding protein G)

Gene
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
29942
Gene name Gene Name - the full gene name approved by the HGNC.
Purine rich element binding protein G
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
PURG
Synonyms (NCBI Gene) Gene synonyms aliases
PURG-A, PURG-B, PURGA, PURGB
Chromosome Chromosome number
8
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
8p12
Summary Summary of gene provided in NCBI Entrez Gene.
The exact function of this gene is not known, however, its encoded product is highly similar to purine-rich element binding protein A. The latter is a DNA-binding protein which binds preferentially to the single strand of the purine-rich element termed PU
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(376)
miRTarBase ID miRNA Experiments Reference
MIRT020365 hsa-miR-29c-3p Sequencing 20371350
MIRT510901 hsa-miR-186-5p HITS-CLIP 21572407
MIRT506002 hsa-miR-6507-5p HITS-CLIP 21572407
MIRT510900 hsa-miR-1277-5p HITS-CLIP 21572407
MIRT521555 hsa-miR-4789-3p HITS-CLIP 21572407
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(11)
GO ID Ontology Definition Evidence Reference
GO:0000977 Function RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
GO:0000977 Function RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0003677 Function DNA binding IEA
GO:0003723 Function RNA binding HDA 22681889
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
618041 17930 ENSG00000172733
Protein
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Q9UJV8
Protein name Purine-rich element-binding protein gamma (Purine-rich element-binding protein G)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04845 PurA 57 → 321 PurA ssDNA and RNA-binding protein Family
Tissue specificity TISSUE SPECIFICITY: Isoform 1 is expressed in testis and glioblastoma. Isoform 2 is expressed in fetal lung. {ECO:0000269|PubMed:12034829}.
Sequence
Sequence length 347
Interactions View interactions
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide Unknown Diseases (4)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Diabetes Type 2 diabetes N/A N/A GWAS
Hypertension Essential hypertension (time to event), Hypertension (confirmatory factor analysis Factor 12) N/A N/A GWAS
Insomnia Insomnia N/A N/A GWAS
Metabolic Syndrome Metabolic syndrome N/A N/A GWAS
Show/Hide Text Mining Associations (2)
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Neoplasms Associate 12034829
Werner Syndrome Associate 12034829