Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	29923
Gene name Gene Name - the full gene name approved by the HGNC.	Hypoxia inducible lipid droplet associated
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	HILPDA
Synonyms (NCBI Gene) Gene synonyms aliases	C7orf68, HIG-2, HIG2
Chromosome Chromosome number	7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	7q32.1

Show/Hide all(60)

miRTarBase ID	miRNA	Experiments	Reference
MIRT679605	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT679604	hsa-miR-764	HITS-CLIP	23824327
MIRT679603	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT679602	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT679601	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT392627	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT679600	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT679599	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT679598	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT679597	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT679596	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT679595	hsa-miR-640	HITS-CLIP	23824327
MIRT679605	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT679604	hsa-miR-764	HITS-CLIP	23824327
MIRT679603	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT679602	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT679601	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT392627	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT679600	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT679599	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT679598	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT679597	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT679596	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT679595	hsa-miR-640	HITS-CLIP	23824327
MIRT491085	hsa-miR-5683	PAR-CLIP	23592263
MIRT491084	hsa-miR-4476	PAR-CLIP	23592263
MIRT491082	hsa-miR-6876-5p	PAR-CLIP	23592263
MIRT491083	hsa-miR-296-3p	PAR-CLIP	23592263
MIRT491081	hsa-miR-1324	PAR-CLIP	23592263
MIRT491080	hsa-miR-651-5p	PAR-CLIP	23592263
MIRT679605	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT679604	hsa-miR-764	HITS-CLIP	23824327
MIRT679603	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT679602	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT679601	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT392627	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT679600	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT679599	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT679598	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT679597	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT679596	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT679595	hsa-miR-640	HITS-CLIP	23824327
MIRT679605	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT679604	hsa-miR-764	HITS-CLIP	23824327
MIRT679603	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT679602	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT679601	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT392627	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT679600	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT679599	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT679598	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT679597	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT679596	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT679595	hsa-miR-640	HITS-CLIP	23824327
MIRT491085	hsa-miR-5683	PAR-CLIP	23592263
MIRT491084	hsa-miR-4476	PAR-CLIP	23592263
MIRT491082	hsa-miR-6876-5p	PAR-CLIP	23592263
MIRT491083	hsa-miR-296-3p	PAR-CLIP	23592263
MIRT491081	hsa-miR-1324	PAR-CLIP	23592263
MIRT491080	hsa-miR-651-5p	PAR-CLIP	23592263

Show/Hide all(21)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001819	Process	Positive regulation of cytokine production	IDA	20624928
GO:0001819	Process	Positive regulation of cytokine production	IEA
GO:0005102	Function	Signaling receptor binding	IPI	15930302
GO:0005515	Function	Protein binding	IPI	15930302, 25416956
GO:0005576	Component	Extracellular region	IEA
GO:0005615	Component	Extracellular space	IDA	15930302
GO:0005654	Component	Nucleoplasm	IDA
GO:0005811	Component	Lipid droplet	IBA
GO:0005811	Component	Lipid droplet	IDA	20624928
GO:0005811	Component	Lipid droplet	IEA
GO:0005829	Component	Cytosol	TAS
GO:0008284	Process	Positive regulation of cell population proliferation	IDA	15930302
GO:0008284	Process	Positive regulation of cell population proliferation	IEA
GO:0009986	Component	Cell surface	IDA	15930302
GO:0010884	Process	Positive regulation of lipid storage	IDA	20624928
GO:0010884	Process	Positive regulation of lipid storage	IEA
GO:0016020	Component	Membrane	IEA
GO:0030141	Component	Secretory granule	IDA	15930302
GO:0035425	Process	Autocrine signaling	IBA
GO:0035425	Process	Autocrine signaling	IDA	15930302
GO:0071456	Process	Cellular response to hypoxia	IEP	10690527

MIM	HGNC	e!Ensembl
617905	28859	ENSG00000135245

Protein

UniProt ID

Q9Y5L2

Protein name

Hypoxia-inducible lipid droplet-associated protein (Hypoxia-inducible gene 2 protein)

Protein function

Increases intracellular lipid accumulation. Stimulates expression of cytokines including IL6, MIF and VEGFA. Enhances cell growth and proliferation.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF15220	HILPDA	1 → 63	Hypoxia-inducible lipid droplet-associated	Family

Tissue specificity

TISSUE SPECIFICITY: Highly expressed in renal cell carcinoma cells but barely detectable in adjacent normal kidney tissue. Detected in some cervical and endometrial cancers. Expression also detected in fetal kidney with little or no expression observed in

Sequence

MKHVLNLYLLGVVLTLLSIFVRVMESLEGLLESPSPGTSWTTRSQLANTEPTKGLPDHPS
RSM

Sequence length

Interactions

View interactions

	Reactome
			Lipid particle organization

HILPDA (hypoxia inducible lipid droplet associated)