HILPDA (hypoxia inducible lipid droplet associated)

Gene
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
29923
Gene name Gene Name - the full gene name approved by the HGNC.
Hypoxia inducible lipid droplet associated
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
HILPDA
Synonyms (NCBI Gene) Gene synonyms aliases
C7orf68, HIG-2, HIG2
Chromosome Chromosome number
7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
7q32.1
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(60)
miRTarBase ID miRNA Experiments Reference
MIRT679605 hsa-miR-125a-3p HITS-CLIP 23824327
MIRT679604 hsa-miR-764 HITS-CLIP 23824327
MIRT679603 hsa-miR-3934-5p HITS-CLIP 23824327
MIRT679602 hsa-miR-186-3p HITS-CLIP 23824327
MIRT679601 hsa-miR-1224-3p HITS-CLIP 23824327
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(17)
GO ID Ontology Definition Evidence Reference
GO:0001819 Process Positive regulation of cytokine production IDA 20624928
GO:0005102 Function Signaling receptor binding IPI 15930302
GO:0005515 Function Protein binding IPI 15930302, 25416956
GO:0005615 Component Extracellular space IDA 15930302
GO:0005654 Component Nucleoplasm IDA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
617905 28859 ENSG00000135245
Protein
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Q9Y5L2
Protein name Hypoxia-inducible lipid droplet-associated protein (Hypoxia-inducible gene 2 protein)
Protein function Increases intracellular lipid accumulation. Stimulates expression of cytokines including IL6, MIF and VEGFA. Enhances cell growth and proliferation.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15220 HILPDA 1 → 63 Hypoxia-inducible lipid droplet-associated Family
Tissue specificity TISSUE SPECIFICITY: Highly expressed in renal cell carcinoma cells but barely detectable in adjacent normal kidney tissue. Detected in some cervical and endometrial cancers. Expression also detected in fetal kidney with little or no expression observed in
Sequence
Sequence length 63
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
  Reactome
    Lipid particle organization
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide Causal Diseases (1)
Causal
Disease term Disease name dbSNP ID References
Lung cancer Malignant neoplasm of lung rs121913530, rs121913529, rs878855122, rs1057519784, rs770315135 27935865
Show/Hide Text Mining Associations (20)
Associations from Text Mining
Disease Name Relationship Type References
Adenocarcinoma Associate 20134266
Adenocarcinoma Clear Cell Associate 20134266
Aortic Aneurysm Abdominal Associate 29191809
Carcinoma Hepatocellular Associate 36862910
Carcinoma Ovarian Epithelial Associate 20134266
Carcinoma Renal Cell Associate 20679884, 24416375, 27757561
Glioblastoma Associate 20671264, 34059134
Hypoxia Associate 25889814, 29256392
Hypoxia Stimulate 27765905
Hypoxia Brain Associate 20671264