EEF2K (eukaryotic elongation factor 2 kinase)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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29904 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Eukaryotic elongation factor 2 kinase |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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EEF2K |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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CaMKIII, HSU93850, eEF-2K |
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Chromosome
Chromosome number
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16 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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16p12.2 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||||||||||||
| UniProt ID | O00418 | ||||||||||||||||||||
| Protein name | Eukaryotic elongation factor 2 kinase (eEF-2 kinase) (eEF-2K) (EC 2.7.11.20) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase) | ||||||||||||||||||||
| Protein function | Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders | ||||||||||||||||||||
| PDB | 5J8H , 5KS5 , 6NX4 , 7SHQ , 8FNY , 8FO6 , 8GM4 , 8GM5 | ||||||||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 725 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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