Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	29886
Gene name Gene Name - the full gene name approved by the HGNC.	Sorting nexin 8
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	SNX8
Synonyms (NCBI Gene) Gene synonyms aliases	Mvp1
Chromosome Chromosome number	7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	7p22.3

Show/Hide all(198)

miRTarBase ID	miRNA	Experiments	Reference
MIRT048293	hsa-miR-107	CLASH	23622248
MIRT038133	hsa-miR-423-5p	CLASH	23622248
MIRT719946	hsa-miR-4714-5p	HITS-CLIP	19536157
MIRT719945	hsa-miR-514a-5p	HITS-CLIP	19536157
MIRT719944	hsa-miR-3664-5p	HITS-CLIP	19536157
MIRT719943	hsa-miR-1915-5p	HITS-CLIP	19536157
MIRT719942	hsa-miR-518c-5p	HITS-CLIP	19536157
MIRT719941	hsa-miR-24-1-5p	HITS-CLIP	19536157
MIRT719939	hsa-miR-24-2-5p	HITS-CLIP	19536157
MIRT719940	hsa-miR-4312	HITS-CLIP	19536157
MIRT719938	hsa-miR-4774-3p	HITS-CLIP	19536157
MIRT719946	hsa-miR-4714-5p	HITS-CLIP	19536157
MIRT719945	hsa-miR-514a-5p	HITS-CLIP	19536157
MIRT719944	hsa-miR-3664-5p	HITS-CLIP	19536157
MIRT719943	hsa-miR-1915-5p	HITS-CLIP	19536157
MIRT719942	hsa-miR-518c-5p	HITS-CLIP	19536157
MIRT719941	hsa-miR-24-1-5p	HITS-CLIP	19536157
MIRT719939	hsa-miR-24-2-5p	HITS-CLIP	19536157
MIRT719940	hsa-miR-4312	HITS-CLIP	19536157
MIRT719938	hsa-miR-4774-3p	HITS-CLIP	19536157
MIRT719946	hsa-miR-4714-5p	HITS-CLIP	19536157
MIRT719945	hsa-miR-514a-5p	HITS-CLIP	19536157
MIRT719944	hsa-miR-3664-5p	HITS-CLIP	19536157
MIRT719943	hsa-miR-1915-5p	HITS-CLIP	19536157
MIRT719942	hsa-miR-518c-5p	HITS-CLIP	19536157
MIRT719941	hsa-miR-24-1-5p	HITS-CLIP	19536157
MIRT719939	hsa-miR-24-2-5p	HITS-CLIP	19536157
MIRT719940	hsa-miR-4312	HITS-CLIP	19536157
MIRT719938	hsa-miR-4774-3p	HITS-CLIP	19536157
MIRT719946	hsa-miR-4714-5p	HITS-CLIP	19536157
MIRT719945	hsa-miR-514a-5p	HITS-CLIP	19536157
MIRT719944	hsa-miR-3664-5p	HITS-CLIP	19536157
MIRT719943	hsa-miR-1915-5p	HITS-CLIP	19536157
MIRT719942	hsa-miR-518c-5p	HITS-CLIP	19536157
MIRT719941	hsa-miR-24-1-5p	HITS-CLIP	19536157
MIRT719939	hsa-miR-24-2-5p	HITS-CLIP	19536157
MIRT719940	hsa-miR-4312	HITS-CLIP	19536157
MIRT719938	hsa-miR-4774-3p	HITS-CLIP	19536157
MIRT1378321	hsa-miR-1207-5p	CLIP-seq
MIRT1378322	hsa-miR-1470	CLIP-seq
MIRT1378323	hsa-miR-1537	CLIP-seq
MIRT1378324	hsa-miR-15a	CLIP-seq
MIRT1378325	hsa-miR-15b	CLIP-seq
MIRT1378326	hsa-miR-16	CLIP-seq
MIRT1378327	hsa-miR-185	CLIP-seq
MIRT1378328	hsa-miR-195	CLIP-seq
MIRT1378329	hsa-miR-30a	CLIP-seq
MIRT1378330	hsa-miR-30b	CLIP-seq
MIRT1378331	hsa-miR-30c	CLIP-seq
MIRT1378332	hsa-miR-30d	CLIP-seq
MIRT1378333	hsa-miR-30e	CLIP-seq
MIRT1378334	hsa-miR-3135b	CLIP-seq
MIRT1378335	hsa-miR-3607-5p	CLIP-seq
MIRT1378336	hsa-miR-3616-5p	CLIP-seq
MIRT1378337	hsa-miR-3622b-5p	CLIP-seq
MIRT1378338	hsa-miR-3647-5p	CLIP-seq
MIRT1378339	hsa-miR-3652	CLIP-seq
MIRT1378340	hsa-miR-3714	CLIP-seq
MIRT1378341	hsa-miR-424	CLIP-seq
MIRT1378342	hsa-miR-4270	CLIP-seq
MIRT1378343	hsa-miR-4287	CLIP-seq
MIRT1378344	hsa-miR-4306	CLIP-seq
MIRT1378345	hsa-miR-4430	CLIP-seq
MIRT1378346	hsa-miR-4436b-3p	CLIP-seq
MIRT1378347	hsa-miR-4441	CLIP-seq
MIRT1378348	hsa-miR-4469	CLIP-seq
MIRT1378349	hsa-miR-4476	CLIP-seq
MIRT1378350	hsa-miR-4644	CLIP-seq
MIRT1378351	hsa-miR-4667-3p	CLIP-seq
MIRT1378352	hsa-miR-4670-3p	CLIP-seq
MIRT1378353	hsa-miR-4685-3p	CLIP-seq
MIRT1378354	hsa-miR-4690-3p	CLIP-seq
MIRT1378355	hsa-miR-4698	CLIP-seq
MIRT1378356	hsa-miR-4708-5p	CLIP-seq
MIRT1378357	hsa-miR-4763-3p	CLIP-seq
MIRT1378358	hsa-miR-497	CLIP-seq
MIRT1378359	hsa-miR-532-3p	CLIP-seq
MIRT1378360	hsa-miR-573	CLIP-seq
MIRT1378361	hsa-miR-625	CLIP-seq
MIRT1378362	hsa-miR-662	CLIP-seq
MIRT1378363	hsa-miR-922	CLIP-seq
MIRT2112812	hsa-miR-1184	CLIP-seq
MIRT2112813	hsa-miR-1226	CLIP-seq
MIRT2112814	hsa-miR-1275	CLIP-seq
MIRT2112815	hsa-miR-1289	CLIP-seq
MIRT2112816	hsa-miR-146a	CLIP-seq
MIRT2112817	hsa-miR-146b-5p	CLIP-seq
MIRT2112818	hsa-miR-214	CLIP-seq
MIRT2112819	hsa-miR-3127-3p	CLIP-seq
MIRT2112820	hsa-miR-3180-5p	CLIP-seq
MIRT2112821	hsa-miR-3183	CLIP-seq
MIRT2112822	hsa-miR-3189-3p	CLIP-seq
MIRT2112823	hsa-miR-338-3p	CLIP-seq
MIRT2112824	hsa-miR-3615	CLIP-seq
MIRT2112825	hsa-miR-3619-5p	CLIP-seq
MIRT2112826	hsa-miR-3620	CLIP-seq
MIRT1378340	hsa-miR-3714	CLIP-seq
MIRT2112827	hsa-miR-3919	CLIP-seq
MIRT2112828	hsa-miR-3925-5p	CLIP-seq
MIRT2112829	hsa-miR-412	CLIP-seq
MIRT2112830	hsa-miR-4251	CLIP-seq
MIRT1378342	hsa-miR-4270	CLIP-seq
MIRT2112831	hsa-miR-4290	CLIP-seq
MIRT2112832	hsa-miR-4432	CLIP-seq
MIRT2112833	hsa-miR-4433	CLIP-seq
MIRT1378347	hsa-miR-4441	CLIP-seq
MIRT2112834	hsa-miR-4459	CLIP-seq
MIRT2112835	hsa-miR-4488	CLIP-seq
MIRT2112836	hsa-miR-4496	CLIP-seq
MIRT2112837	hsa-miR-4642	CLIP-seq
MIRT2112838	hsa-miR-4665-5p	CLIP-seq
MIRT1378351	hsa-miR-4667-3p	CLIP-seq
MIRT2112839	hsa-miR-4675	CLIP-seq
MIRT1378354	hsa-miR-4690-3p	CLIP-seq
MIRT2112840	hsa-miR-4690-5p	CLIP-seq
MIRT2112841	hsa-miR-4697-5p	CLIP-seq
MIRT2112842	hsa-miR-4706	CLIP-seq
MIRT1378356	hsa-miR-4708-5p	CLIP-seq
MIRT2112843	hsa-miR-4720-5p	CLIP-seq
MIRT2112844	hsa-miR-4722-5p	CLIP-seq
MIRT2112845	hsa-miR-4723-3p	CLIP-seq
MIRT2112846	hsa-miR-4725-5p	CLIP-seq
MIRT2112847	hsa-miR-4741	CLIP-seq
MIRT2112848	hsa-miR-4749-5p	CLIP-seq
MIRT2112849	hsa-miR-4763-5p	CLIP-seq
MIRT2112850	hsa-miR-4768-3p	CLIP-seq
MIRT2112851	hsa-miR-4799-3p	CLIP-seq
MIRT2112852	hsa-miR-504	CLIP-seq
MIRT2112853	hsa-miR-520a-5p	CLIP-seq
MIRT2112854	hsa-miR-525-5p	CLIP-seq
MIRT2112855	hsa-miR-589	CLIP-seq
MIRT2112856	hsa-miR-621	CLIP-seq
MIRT2112857	hsa-miR-634	CLIP-seq
MIRT2112858	hsa-miR-635	CLIP-seq
MIRT2112859	hsa-miR-649	CLIP-seq
MIRT2112860	hsa-miR-761	CLIP-seq
MIRT2112861	hsa-miR-885-3p	CLIP-seq
MIRT2112812	hsa-miR-1184	CLIP-seq
MIRT2112813	hsa-miR-1226	CLIP-seq
MIRT2335810	hsa-miR-1229	CLIP-seq
MIRT2335811	hsa-miR-1291	CLIP-seq
MIRT1378322	hsa-miR-1470	CLIP-seq
MIRT1378327	hsa-miR-185	CLIP-seq
MIRT2335812	hsa-miR-22	CLIP-seq
MIRT2335813	hsa-miR-3065-3p	CLIP-seq
MIRT2112819	hsa-miR-3127-3p	CLIP-seq
MIRT1378334	hsa-miR-3135b	CLIP-seq
MIRT2335814	hsa-miR-328	CLIP-seq
MIRT2112823	hsa-miR-338-3p	CLIP-seq
MIRT1378342	hsa-miR-4270	CLIP-seq
MIRT2335815	hsa-miR-4279	CLIP-seq
MIRT2112831	hsa-miR-4290	CLIP-seq
MIRT1378344	hsa-miR-4306	CLIP-seq
MIRT2335816	hsa-miR-4421	CLIP-seq
MIRT1378346	hsa-miR-4436b-3p	CLIP-seq
MIRT2335817	hsa-miR-4438	CLIP-seq
MIRT1378347	hsa-miR-4441	CLIP-seq
MIRT1378348	hsa-miR-4469	CLIP-seq
MIRT1378350	hsa-miR-4644	CLIP-seq
MIRT1378351	hsa-miR-4667-3p	CLIP-seq
MIRT1378361	hsa-miR-625	CLIP-seq
MIRT2112857	hsa-miR-634	CLIP-seq
MIRT2112812	hsa-miR-1184	CLIP-seq
MIRT2394939	hsa-miR-1976	CLIP-seq
MIRT2394940	hsa-miR-2467-3p	CLIP-seq
MIRT2394941	hsa-miR-3158-5p	CLIP-seq
MIRT2394942	hsa-miR-3184	CLIP-seq
MIRT2394943	hsa-miR-3678-3p	CLIP-seq
MIRT2394944	hsa-miR-370	CLIP-seq
MIRT1378342	hsa-miR-4270	CLIP-seq
MIRT1378347	hsa-miR-4441	CLIP-seq
MIRT2460229	hsa-miR-1224-3p	CLIP-seq
MIRT2460230	hsa-miR-124	CLIP-seq
MIRT2460231	hsa-miR-1293	CLIP-seq
MIRT1378322	hsa-miR-1470	CLIP-seq
MIRT2460232	hsa-miR-1913	CLIP-seq
MIRT2394939	hsa-miR-1976	CLIP-seq
MIRT2394940	hsa-miR-2467-3p	CLIP-seq
MIRT2460233	hsa-miR-3202	CLIP-seq
MIRT2460234	hsa-miR-324-3p	CLIP-seq
MIRT2460235	hsa-miR-4297	CLIP-seq
MIRT2460236	hsa-miR-4313	CLIP-seq
MIRT1378348	hsa-miR-4469	CLIP-seq
MIRT1378349	hsa-miR-4476	CLIP-seq
MIRT2460237	hsa-miR-4483	CLIP-seq
MIRT1378351	hsa-miR-4667-3p	CLIP-seq
MIRT2460238	hsa-miR-4722-3p	CLIP-seq
MIRT2460239	hsa-miR-506	CLIP-seq
MIRT2460230	hsa-miR-124	CLIP-seq
MIRT2630010	hsa-miR-2355-5p	CLIP-seq
MIRT2630011	hsa-miR-3622a-5p	CLIP-seq
MIRT2630012	hsa-miR-3938	CLIP-seq
MIRT1378351	hsa-miR-4667-3p	CLIP-seq
MIRT2460239	hsa-miR-506	CLIP-seq
MIRT2630013	hsa-miR-564	CLIP-seq
MIRT2630010	hsa-miR-2355-5p	CLIP-seq
MIRT2630012	hsa-miR-3938	CLIP-seq
MIRT1378351	hsa-miR-4667-3p	CLIP-seq

Show/Hide all(9)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	17474147, 32296183
GO:0005829	Component	Cytosol	IEA
GO:0006886	Process	Intracellular protein transport	IMP	19782049
GO:0030904	Component	Retromer complex	IDA	19782049
GO:0031901	Component	Early endosome membrane	IDA	19782049
GO:0034498	Process	Early endosome to Golgi transport	IMP	19782049
GO:0035091	Function	Phosphatidylinositol binding	IMP	19782049
GO:0042802	Function	Identical protein binding	IPI	23085988
GO:0043231	Component	Intracellular membrane-bounded organelle	IDA

MIM	HGNC	e!Ensembl
614905	14972	ENSG00000106266

Protein

UniProt ID

Q9Y5X2

Protein name

Sorting nexin-8

Protein function

May be involved in several stages of intracellular trafficking. May play a role in intracellular protein transport from early endosomes to the trans-Golgi network.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00787	PX	96 → 178	PX domain	Domain

Sequence

MTGRAMDPLPAAAVGAAAEAEADEEADPPASDLPTPQAIEPQAIVQQVPAPSRMQMPQGN
PLLLSHTLQELLARDTVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFQEML
LHKFPYRMVPALPPKRMLGADREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSGS
DVQNKLKESAQCVGDEFLNCKLATRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRAE
RIASRAIDNAADLLIFGKELSAIGSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLAD
KAAQQGKQEENDVVEKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMMSAT
AQNREPESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHVYLPLTSHILRAFVN
SQIQGHKEMSKVWNDLRPKLSCLFAGPHSTLTPPCSPPEDGLCPH

Sequence length

465

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Colorectal cancer	Colorectal Carcinoma	rs137854568, rs137854573, rs137854575, rs387906234, rs121908380, rs121908702, rs267606674, rs794729661, rs121909055, rs281865417, rs267606884, rs28934575, rs587776769, rs104893815, rs587776800 View all (467 more)

Show/Hide Unknown Diseases (3)

Disease term	Disease name	References	Source
Unknown
Head and neck cancer	Malignant Head and Neck Neoplasm	29884837	ClinVar
Alzheimer disease	Alzheimer disease		GWAS
Schizophrenia	Schizophrenia		GWAS

Show/Hide Text Mining Associations (3)

Disease Name	Relationship Type	References
Associations from Text Mining
Alzheimer Disease	Associate	34524084
Head and Neck Neoplasms	Associate	29884837
Neuralgia	Associate	29884837

SNX8 (sorting nexin 8)