Gene Gene information from NCBI Gene database.
Entrez ID 29799
Gene name Yippee like 1
Gene symbol YPEL1
Synonyms (NCBI Gene)
FKSG3
Chromosome 22
Chromosome location 22q11.21-q11.22
Summary This gene is located in the region associated with DiGeorge syndrome on chromosome 22. The encoded protein localizes to the centrosome and nucleolus and may play a role in the regulation of cell division. [provided by RefSeq, Feb 2015]
miRNA miRNA information provided by mirtarbase database.
411
miRTarBase ID miRNA Experiments Reference
MIRT019272 hsa-miR-148b-3p Microarray 17612493
MIRT021892 hsa-miR-128-3p Microarray 17612493
MIRT723140 hsa-miR-4686 HITS-CLIP 19536157
MIRT723139 hsa-miR-148a-3p HITS-CLIP 19536157
MIRT019272 hsa-miR-148b-3p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
2
GO ID Ontology Definition Evidence Reference
GO:0005634 Component Nucleus IEA
GO:0046872 Function Metal ion binding IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
608082 12845 ENSG00000100027
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O60688
Protein name Protein yippee-like 1
Protein function May play a role in epithelioid conversion of fibroblasts.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03226 Yippee-Mis18 19 119 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Domain
Sequence
Sequence length 119
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
8
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
AMYOTROPHIC LATERAL SCLEROSIS GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
BILE DUCT CANCER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
BIPOLAR DISORDER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
INSOMNIA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Carcinoma Renal Cell Associate 35674183
★☆☆☆☆
Found in Text Mining only
Stomach Neoplasms Associate 31599416
★☆☆☆☆
Found in Text Mining only