SAP30BP (SAP30 binding protein)

Gene

• Entrez ID: 29115
• Gene name: SAP30 binding protein
• Gene symbol: SAP30BP
• Synonyms (NCBI Gene): HCNGP, HTRG, HTRP
• Chromosome: 17
• Chromosome location: 17q25.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT048958	hsa-miR-92a-3p	CLASH	23622248
MIRT048958	hsa-miR-92a-3p	CLASH	23622248
MIRT043616	hsa-miR-151a-3p	CLASH	23622248
MIRT043246	hsa-miR-324-5p	CLASH	23622248
MIRT1325799	hsa-miR-1207-5p	CLIP-seq
MIRT1325800	hsa-miR-1273f	CLIP-seq
MIRT1325801	hsa-miR-1286	CLIP-seq
MIRT1325802	hsa-miR-143	CLIP-seq
MIRT1325803	hsa-miR-148a	CLIP-seq
MIRT1325804	hsa-miR-148b	CLIP-seq
MIRT1325805	hsa-miR-152	CLIP-seq
MIRT1325806	hsa-miR-1825	CLIP-seq
MIRT1325807	hsa-miR-3125	CLIP-seq
MIRT1325808	hsa-miR-3151	CLIP-seq
MIRT1325809	hsa-miR-3200-5p	CLIP-seq
MIRT1325810	hsa-miR-3202	CLIP-seq
MIRT1325811	hsa-miR-3675-5p	CLIP-seq
MIRT1325812	hsa-miR-3916	CLIP-seq
MIRT1325813	hsa-miR-3945	CLIP-seq
MIRT1325814	hsa-miR-4251	CLIP-seq
MIRT1325815	hsa-miR-4283	CLIP-seq
MIRT1325816	hsa-miR-4329	CLIP-seq
MIRT1325817	hsa-miR-4476	CLIP-seq
MIRT1325818	hsa-miR-4480	CLIP-seq
MIRT1325819	hsa-miR-4489	CLIP-seq
MIRT1325820	hsa-miR-4708-5p	CLIP-seq
MIRT1325821	hsa-miR-4722-5p	CLIP-seq
MIRT1325822	hsa-miR-4736	CLIP-seq
MIRT1325823	hsa-miR-4763-3p	CLIP-seq
MIRT1325824	hsa-miR-4768-3p	CLIP-seq
MIRT1325825	hsa-miR-4770	CLIP-seq
MIRT1325826	hsa-miR-486-3p	CLIP-seq
MIRT1325827	hsa-miR-548al	CLIP-seq
MIRT1325828	hsa-miR-582-5p	CLIP-seq
MIRT1325829	hsa-miR-633	CLIP-seq
MIRT1325830	hsa-miR-873	CLIP-seq
MIRT2096681	hsa-miR-1285	CLIP-seq
MIRT2096682	hsa-miR-224	CLIP-seq
MIRT2096683	hsa-miR-300	CLIP-seq
MIRT2096684	hsa-miR-3156-3p	CLIP-seq
MIRT2096685	hsa-miR-3175	CLIP-seq
MIRT2096686	hsa-miR-3187-5p	CLIP-seq
MIRT2096687	hsa-miR-34a	CLIP-seq
MIRT2096688	hsa-miR-34c-5p	CLIP-seq
MIRT2096689	hsa-miR-3545-5p	CLIP-seq
MIRT2096690	hsa-miR-381	CLIP-seq
MIRT2096691	hsa-miR-4301	CLIP-seq
MIRT2096692	hsa-miR-449a	CLIP-seq
MIRT2096693	hsa-miR-449b	CLIP-seq
MIRT2096694	hsa-miR-4666-3p	CLIP-seq
MIRT2096695	hsa-miR-532-3p	CLIP-seq
MIRT2096696	hsa-miR-612	CLIP-seq
MIRT1325829	hsa-miR-633	CLIP-seq
MIRT2096697	hsa-miR-642b	CLIP-seq
MIRT2096698	hsa-miR-764	CLIP-seq
MIRT1325806	hsa-miR-1825	CLIP-seq
MIRT2321042	hsa-miR-188-3p	CLIP-seq
MIRT2321043	hsa-miR-1910	CLIP-seq
MIRT2096683	hsa-miR-300	CLIP-seq
MIRT2321044	hsa-miR-3064-5p	CLIP-seq
MIRT2321045	hsa-miR-3140-5p	CLIP-seq
MIRT1325808	hsa-miR-3151	CLIP-seq
MIRT2321046	hsa-miR-3158-3p	CLIP-seq
MIRT1325810	hsa-miR-3202	CLIP-seq
MIRT1325811	hsa-miR-3675-5p	CLIP-seq
MIRT2096690	hsa-miR-381	CLIP-seq
MIRT1325813	hsa-miR-3945	CLIP-seq
MIRT2321047	hsa-miR-4257	CLIP-seq
MIRT1325815	hsa-miR-4283	CLIP-seq
MIRT1325817	hsa-miR-4476	CLIP-seq
MIRT1325819	hsa-miR-4489	CLIP-seq
MIRT2321048	hsa-miR-4539	CLIP-seq
MIRT2321049	hsa-miR-4652-5p	CLIP-seq
MIRT2321050	hsa-miR-4659a-5p	CLIP-seq
MIRT2321051	hsa-miR-4659b-5p	CLIP-seq
MIRT2096694	hsa-miR-4666-3p	CLIP-seq
MIRT1325821	hsa-miR-4722-5p	CLIP-seq
MIRT1325826	hsa-miR-486-3p	CLIP-seq
MIRT2321052	hsa-miR-520d-5p	CLIP-seq
MIRT2321053	hsa-miR-524-5p	CLIP-seq
MIRT2096695	hsa-miR-532-3p	CLIP-seq
MIRT2321054	hsa-miR-542-5p	CLIP-seq
MIRT2321055	hsa-miR-582-3p	CLIP-seq
MIRT2617067	hsa-miR-1	CLIP-seq
MIRT2617068	hsa-miR-10a	CLIP-seq
MIRT2617069	hsa-miR-10b	CLIP-seq
MIRT2617070	hsa-miR-1229	CLIP-seq
MIRT2617071	hsa-miR-1237	CLIP-seq
MIRT2617072	hsa-miR-1245	CLIP-seq
MIRT2617073	hsa-miR-125a-3p	CLIP-seq
MIRT2617074	hsa-miR-1266	CLIP-seq
MIRT2617075	hsa-miR-1281	CLIP-seq
MIRT2096681	hsa-miR-1285	CLIP-seq
MIRT2617076	hsa-miR-129-3p	CLIP-seq
MIRT2617077	hsa-miR-1299	CLIP-seq
MIRT2617078	hsa-miR-1343	CLIP-seq
MIRT2617079	hsa-miR-149	CLIP-seq
MIRT1325806	hsa-miR-1825	CLIP-seq
MIRT2321043	hsa-miR-1910	CLIP-seq
MIRT2617080	hsa-miR-199a-5p	CLIP-seq
MIRT2617081	hsa-miR-199b-5p	CLIP-seq
MIRT2617082	hsa-miR-206	CLIP-seq
MIRT2096683	hsa-miR-300	CLIP-seq
MIRT2617083	hsa-miR-3121-3p	CLIP-seq
MIRT2617084	hsa-miR-3130-3p	CLIP-seq
MIRT2321045	hsa-miR-3140-5p	CLIP-seq
MIRT2617085	hsa-miR-3150a-3p	CLIP-seq
MIRT2096684	hsa-miR-3156-3p	CLIP-seq
MIRT2096685	hsa-miR-3175	CLIP-seq
MIRT2617086	hsa-miR-3179	CLIP-seq
MIRT2617087	hsa-miR-3183	CLIP-seq
MIRT2096686	hsa-miR-3187-5p	CLIP-seq
MIRT2617088	hsa-miR-331-3p	CLIP-seq
MIRT2617089	hsa-miR-339-5p	CLIP-seq
MIRT2096687	hsa-miR-34a	CLIP-seq
MIRT2096688	hsa-miR-34c-5p	CLIP-seq
MIRT2096689	hsa-miR-3545-5p	CLIP-seq
MIRT2617090	hsa-miR-3609	CLIP-seq
MIRT2617091	hsa-miR-3614-3p	CLIP-seq
MIRT2617092	hsa-miR-3650	CLIP-seq
MIRT2617093	hsa-miR-3657	CLIP-seq
MIRT2617094	hsa-miR-3663-5p	CLIP-seq
MIRT2617095	hsa-miR-3664-3p	CLIP-seq
MIRT2617096	hsa-miR-3667-3p	CLIP-seq
MIRT2617097	hsa-miR-3673	CLIP-seq
MIRT2096690	hsa-miR-381	CLIP-seq
MIRT2617098	hsa-miR-3925-3p	CLIP-seq
MIRT2617099	hsa-miR-3934	CLIP-seq
MIRT2617100	hsa-miR-4261	CLIP-seq
MIRT2617101	hsa-miR-4268	CLIP-seq
MIRT2617102	hsa-miR-4279	CLIP-seq
MIRT2617103	hsa-miR-4286	CLIP-seq
MIRT2617104	hsa-miR-4297	CLIP-seq
MIRT2096691	hsa-miR-4301	CLIP-seq
MIRT2617105	hsa-miR-4434	CLIP-seq
MIRT2617106	hsa-miR-4455	CLIP-seq
MIRT2617107	hsa-miR-4474-5p	CLIP-seq
MIRT2096692	hsa-miR-449a	CLIP-seq
MIRT2096693	hsa-miR-449b	CLIP-seq
MIRT2617108	hsa-miR-4516	CLIP-seq
MIRT2617109	hsa-miR-4518	CLIP-seq
MIRT2617110	hsa-miR-4527	CLIP-seq
MIRT2617111	hsa-miR-4531	CLIP-seq
MIRT2321048	hsa-miR-4539	CLIP-seq
MIRT2617112	hsa-miR-4639-3p	CLIP-seq
MIRT2617113	hsa-miR-4642	CLIP-seq
MIRT2096694	hsa-miR-4666-3p	CLIP-seq
MIRT2617114	hsa-miR-4667-5p	CLIP-seq
MIRT2617115	hsa-miR-4669	CLIP-seq
MIRT2617116	hsa-miR-4695-3p	CLIP-seq
MIRT2617117	hsa-miR-4700-5p	CLIP-seq
MIRT2617118	hsa-miR-4723-3p	CLIP-seq
MIRT2617119	hsa-miR-4725-5p	CLIP-seq
MIRT2617120	hsa-miR-4738-3p	CLIP-seq
MIRT2617121	hsa-miR-4782-5p	CLIP-seq
MIRT2617122	hsa-miR-4793-3p	CLIP-seq
MIRT2617123	hsa-miR-4796-3p	CLIP-seq
MIRT2617124	hsa-miR-504	CLIP-seq
MIRT2617125	hsa-miR-516b	CLIP-seq
MIRT2321052	hsa-miR-520d-5p	CLIP-seq
MIRT2617126	hsa-miR-520g	CLIP-seq
MIRT2617127	hsa-miR-520h	CLIP-seq
MIRT2321053	hsa-miR-524-5p	CLIP-seq
MIRT2096695	hsa-miR-532-3p	CLIP-seq
MIRT2617128	hsa-miR-548ah	CLIP-seq
MIRT2617129	hsa-miR-548t	CLIP-seq
MIRT2617130	hsa-miR-566	CLIP-seq
MIRT2617131	hsa-miR-572	CLIP-seq
MIRT2617132	hsa-miR-609	CLIP-seq
MIRT2096696	hsa-miR-612	CLIP-seq
MIRT2617133	hsa-miR-613	CLIP-seq
MIRT2617134	hsa-miR-617	CLIP-seq
MIRT2617135	hsa-miR-637	CLIP-seq
MIRT2096697	hsa-miR-642b	CLIP-seq
MIRT2096698	hsa-miR-764	CLIP-seq
MIRT2617136	hsa-miR-875-3p	CLIP-seq
MIRT2617137	hsa-miR-892b	CLIP-seq
MIRT2617138	hsa-miR-939	CLIP-seq
MIRT2617067	hsa-miR-1	CLIP-seq
MIRT2617068	hsa-miR-10a	CLIP-seq
MIRT2617069	hsa-miR-10b	CLIP-seq
MIRT2617070	hsa-miR-1229	CLIP-seq
MIRT2617071	hsa-miR-1237	CLIP-seq
MIRT2617073	hsa-miR-125a-3p	CLIP-seq
MIRT2617074	hsa-miR-1266	CLIP-seq
MIRT2617075	hsa-miR-1281	CLIP-seq
MIRT2617076	hsa-miR-129-3p	CLIP-seq
MIRT2617077	hsa-miR-1299	CLIP-seq
MIRT2617078	hsa-miR-1343	CLIP-seq
MIRT2617079	hsa-miR-149	CLIP-seq
MIRT1325806	hsa-miR-1825	CLIP-seq
MIRT2321043	hsa-miR-1910	CLIP-seq
MIRT2690198	hsa-miR-1915	CLIP-seq
MIRT2617080	hsa-miR-199a-5p	CLIP-seq
MIRT2617081	hsa-miR-199b-5p	CLIP-seq
MIRT2617082	hsa-miR-206	CLIP-seq
MIRT2096683	hsa-miR-300	CLIP-seq
MIRT2617083	hsa-miR-3121-3p	CLIP-seq
MIRT2617084	hsa-miR-3130-3p	CLIP-seq
MIRT2321045	hsa-miR-3140-5p	CLIP-seq
MIRT2617085	hsa-miR-3150a-3p	CLIP-seq
MIRT2690199	hsa-miR-3153	CLIP-seq
MIRT2321046	hsa-miR-3158-3p	CLIP-seq
MIRT2096685	hsa-miR-3175	CLIP-seq
MIRT2617086	hsa-miR-3179	CLIP-seq
MIRT2617087	hsa-miR-3183	CLIP-seq
MIRT2690200	hsa-miR-3192	CLIP-seq
MIRT2617088	hsa-miR-331-3p	CLIP-seq
MIRT2617089	hsa-miR-339-5p	CLIP-seq
MIRT2617091	hsa-miR-3614-3p	CLIP-seq
MIRT2617092	hsa-miR-3650	CLIP-seq
MIRT2617093	hsa-miR-3657	CLIP-seq
MIRT2617094	hsa-miR-3663-5p	CLIP-seq
MIRT2617095	hsa-miR-3664-3p	CLIP-seq
MIRT2617096	hsa-miR-3667-3p	CLIP-seq
MIRT2617097	hsa-miR-3673	CLIP-seq
MIRT2096690	hsa-miR-381	CLIP-seq
MIRT2617098	hsa-miR-3925-3p	CLIP-seq
MIRT2617099	hsa-miR-3934	CLIP-seq
MIRT2617100	hsa-miR-4261	CLIP-seq
MIRT2617101	hsa-miR-4268	CLIP-seq
MIRT2617102	hsa-miR-4279	CLIP-seq
MIRT2617103	hsa-miR-4286	CLIP-seq
MIRT2617104	hsa-miR-4297	CLIP-seq
MIRT2690201	hsa-miR-4314	CLIP-seq
MIRT2617105	hsa-miR-4434	CLIP-seq
MIRT2617106	hsa-miR-4455	CLIP-seq
MIRT2617107	hsa-miR-4474-5p	CLIP-seq
MIRT2617108	hsa-miR-4516	CLIP-seq
MIRT2617109	hsa-miR-4518	CLIP-seq
MIRT2617110	hsa-miR-4527	CLIP-seq
MIRT2617111	hsa-miR-4531	CLIP-seq
MIRT2321048	hsa-miR-4539	CLIP-seq
MIRT2617112	hsa-miR-4639-3p	CLIP-seq
MIRT2617113	hsa-miR-4642	CLIP-seq
MIRT2690202	hsa-miR-4646-5p	CLIP-seq
MIRT2096694	hsa-miR-4666-3p	CLIP-seq
MIRT2617114	hsa-miR-4667-5p	CLIP-seq
MIRT2690203	hsa-miR-4668-5p	CLIP-seq
MIRT2617115	hsa-miR-4669	CLIP-seq
MIRT2617116	hsa-miR-4695-3p	CLIP-seq
MIRT2617117	hsa-miR-4700-5p	CLIP-seq
MIRT2617118	hsa-miR-4723-3p	CLIP-seq
MIRT2617119	hsa-miR-4725-5p	CLIP-seq
MIRT2690204	hsa-miR-4726-3p	CLIP-seq
MIRT2617120	hsa-miR-4738-3p	CLIP-seq
MIRT2617121	hsa-miR-4782-5p	CLIP-seq
MIRT2617122	hsa-miR-4793-3p	CLIP-seq
MIRT2617123	hsa-miR-4796-3p	CLIP-seq
MIRT2617124	hsa-miR-504	CLIP-seq
MIRT2617125	hsa-miR-516b	CLIP-seq
MIRT2321052	hsa-miR-520d-5p	CLIP-seq
MIRT2617126	hsa-miR-520g	CLIP-seq
MIRT2617127	hsa-miR-520h	CLIP-seq
MIRT2321053	hsa-miR-524-5p	CLIP-seq
MIRT2617130	hsa-miR-566	CLIP-seq
MIRT2617131	hsa-miR-572	CLIP-seq
MIRT2617132	hsa-miR-609	CLIP-seq
MIRT2617133	hsa-miR-613	CLIP-seq
MIRT2617134	hsa-miR-617	CLIP-seq
MIRT2617135	hsa-miR-637	CLIP-seq
MIRT2096697	hsa-miR-642b	CLIP-seq
MIRT2690205	hsa-miR-665	CLIP-seq
MIRT2096698	hsa-miR-764	CLIP-seq
MIRT2617136	hsa-miR-875-3p	CLIP-seq
MIRT2617137	hsa-miR-892b	CLIP-seq
MIRT2617138	hsa-miR-939	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	15496587, 16189514, 18255255, 21516116, 22365833, 25416956, 31515488, 32296183, 32814053, 33961781
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	15496587
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0009615	Process	Response to virus	IEP	15496587
GO:0045111	Component	Intermediate filament cytoskeleton	IDA

Other IDs

• MIM: 610218
• HGNC: 30785
• e!Ensembl: ENSG00000161526

Protein

• UniProt ID: Q9UHR5
• Protein name: SAP30-binding protein (Transcriptional regulator protein HCNGP)
• Protein function: Plays a role in transcriptional repression by promoting histone deacetylase activity, leading to deacetylation of histone H3 (PubMed:21221920). May be involved in the regulation of beta-2-microglobulin genes (By similarity). {ECO:0000250|UniProt
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07818	HCNGP	119 → 213	HCNGP-like protein	Family

• Sequence:

  MAGKKNVLSSLAVYAEDSEPESDGEAGIEAVGSAAEEKGGLVSDAYGEDDFSRLGGDEDG
  YEEEEDENSRQSEDDDSETEKPEADDPKDNTEAEKRDPQELVASFSERVRNMSPDEIKIP
  PEPPGRCSNHLQDKIQKLYERKIKEGMDMNYIIQRKKEFRNPSIYEKLIQFCAIDELGTN
  YPKDMFDPHGWSEDSYYEALAKAQKIEMDKLEKAKKERTKIEFVTGTKKGTTTNATSTTT
  TTASTAVADAQKRKSKWDSAIPVTTIAQPTILTTTATLPAVVTVTTSASGSKTTVISAVG
  TIVKKAKQ

• Sequence length: 308

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
Hepatocellular carcinoma	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PARAPLEGIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ROTATOR CUFF TEAR	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	CTD, Disgenet CTD, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Relationship Type	References	Evidence Score
Diabetes Mellitus Type 2	Associate	24455749	★☆☆☆☆ Found in Text Mining only
Obesity	Associate	24455749	★☆☆☆☆ Found in Text Mining only