LGALSL (galectin like)

Gene

• Entrez ID: 29094
• Gene name: Galectin like
• Gene symbol: LGALSL
• Synonyms (NCBI Gene): GRP, HSPC159
• Chromosome: 2
• Chromosome location: 2p14

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT025108	hsa-miR-181a-5p	Sequencing	20371350
MIRT029067	hsa-miR-26b-5p	Microarray	19088304
MIRT667650	hsa-miR-5088-5p	HITS-CLIP	23824327
MIRT667649	hsa-miR-1470	HITS-CLIP	23824327
MIRT667648	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT667647	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT667646	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT667645	hsa-miR-4469	HITS-CLIP	23824327
MIRT667644	hsa-miR-7106-3p	HITS-CLIP	23824327
MIRT667643	hsa-miR-4470	HITS-CLIP	23824327
MIRT667642	hsa-miR-503-3p	HITS-CLIP	23824327
MIRT667641	hsa-miR-1225-5p	HITS-CLIP	23824327
MIRT667640	hsa-miR-1229-5p	HITS-CLIP	23824327
MIRT667650	hsa-miR-5088-5p	HITS-CLIP	23824327
MIRT667649	hsa-miR-1470	HITS-CLIP	23824327
MIRT667648	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT667647	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT667646	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT667645	hsa-miR-4469	HITS-CLIP	23824327
MIRT667644	hsa-miR-7106-3p	HITS-CLIP	23824327
MIRT667643	hsa-miR-4470	HITS-CLIP	23824327
MIRT667642	hsa-miR-503-3p	HITS-CLIP	23824327
MIRT667641	hsa-miR-1225-5p	HITS-CLIP	23824327
MIRT667640	hsa-miR-1229-5p	HITS-CLIP	23824327

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	21044950, 25416956, 32296183
GO:0030246	Function	Carbohydrate binding	IBA
GO:0030246	Function	Carbohydrate binding	IEA

Other IDs

• MIM: 617902
• HGNC: 25012
• e!Ensembl: ENSG00000119862

Protein

• UniProt ID: Q3ZCW2
• Protein name: Galectin-related protein (Galectin-like protein) (Lectin galactoside-binding-like protein)
• Protein function: Does not bind lactose, and may not bind carbohydrates.
• PDB: 2JJ6, 3B9C
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00337	Gal-bind_lectin	39 → 172	Galactoside-binding lectin	Domain

• Sequence:

  MAGSVADSDAVVKLDDGHLNNSLSSPVQADVYFPRLIVPFCGHIKGGMRPGKKVLVMGIV
  DLNPESFAISLTCGDSEDPPADVAIELKAVFTDRQLLRNSCISGERGEEQSAIPYFPFIP
  DQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQITKLG

• Sequence length: 172

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
AMYOTROPHIC LATERAL SCLEROSIS	—	ClinGen, Disgenet ClinGen, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LIVER CIRRHOSIS, EXPERIMENTAL	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Relationship Type	References	Evidence Score
Multiple Myeloma	Associate	33675538	★☆☆☆☆ Found in Text Mining only
Osteoporosis	Associate	29568943	★☆☆☆☆ Found in Text Mining only
Periodontitis	Associate	39610070	★☆☆☆☆ Found in Text Mining only
Postural Orthostatic Tachycardia Syndrome	Associate	40022872	★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Associate	23052694	★☆☆☆☆ Found in Text Mining only