Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	29079
Gene name Gene Name - the full gene name approved by the HGNC.	Mediator complex subunit 4
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	MED4
Synonyms (NCBI Gene) Gene synonyms aliases	ARC36, DRIP36, HSPC126, TRAP36, VDRIP
Chromosome Chromosome number	13
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	13q14.2
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a component of the Mediator complex. The Mediator complex interacts with DNA-binding gene-specific transcription factors to modulate transcription by RNA polymerase II. Alternatively spliced transcript variants encoding multiple isoforms

Show/Hide all(303)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016676	hsa-miR-425-5p	Sequencing	20371350
MIRT021128	hsa-miR-186-5p	Sequencing	20371350
MIRT023475	hsa-miR-23b-3p	Sequencing	20371350
MIRT571407	hsa-miR-3133	PAR-CLIP	20371350
MIRT021128	hsa-miR-186-5p	PAR-CLIP	20371350
MIRT571405	hsa-miR-452-5p	PAR-CLIP	20371350
MIRT571403	hsa-miR-4676-3p	PAR-CLIP	20371350
MIRT571404	hsa-miR-892c-3p	PAR-CLIP	20371350
MIRT571402	hsa-miR-6752-3p	PAR-CLIP	20371350
MIRT571400	hsa-miR-670-5p	PAR-CLIP	20371350
MIRT571401	hsa-miR-5089-3p	PAR-CLIP	20371350
MIRT547419	hsa-miR-4755-5p	PAR-CLIP	20371350
MIRT547420	hsa-miR-5006-3p	PAR-CLIP	20371350
MIRT547418	hsa-miR-4446-5p	PAR-CLIP	20371350
MIRT571399	hsa-miR-1324	PAR-CLIP	20371350
MIRT547436	hsa-miR-190b	PAR-CLIP	21572407
MIRT547435	hsa-miR-190a-5p	PAR-CLIP	21572407
MIRT547434	hsa-miR-1245a	PAR-CLIP	21572407
MIRT547433	hsa-miR-8079	PAR-CLIP	21572407
MIRT547432	hsa-miR-8062	PAR-CLIP	21572407
MIRT547431	hsa-miR-8076	PAR-CLIP	21572407
MIRT547430	hsa-miR-1246	PAR-CLIP	21572407
MIRT547429	hsa-miR-3689a-5p	PAR-CLIP	21572407
MIRT547428	hsa-miR-3689b-5p	PAR-CLIP	21572407
MIRT547427	hsa-miR-3689e	PAR-CLIP	21572407
MIRT547426	hsa-miR-3689f	PAR-CLIP	21572407
MIRT547425	hsa-miR-3606-5p	PAR-CLIP	21572407
MIRT547424	hsa-miR-921	PAR-CLIP	21572407
MIRT547422	hsa-miR-3924	PAR-CLIP	21572407
MIRT547423	hsa-miR-642a-5p	PAR-CLIP	21572407
MIRT547421	hsa-miR-1261	PAR-CLIP	21572407
MIRT547436	hsa-miR-190b	PAR-CLIP	21572407
MIRT547435	hsa-miR-190a-5p	PAR-CLIP	21572407
MIRT547434	hsa-miR-1245a	PAR-CLIP	21572407
MIRT547433	hsa-miR-8079	PAR-CLIP	21572407
MIRT547432	hsa-miR-8062	PAR-CLIP	21572407
MIRT547431	hsa-miR-8076	PAR-CLIP	21572407
MIRT547430	hsa-miR-1246	PAR-CLIP	21572407
MIRT547429	hsa-miR-3689a-5p	PAR-CLIP	21572407
MIRT547428	hsa-miR-3689b-5p	PAR-CLIP	21572407
MIRT547427	hsa-miR-3689e	PAR-CLIP	21572407
MIRT547426	hsa-miR-3689f	PAR-CLIP	21572407
MIRT547425	hsa-miR-3606-5p	PAR-CLIP	21572407
MIRT547424	hsa-miR-921	PAR-CLIP	21572407
MIRT547422	hsa-miR-3924	PAR-CLIP	21572407
MIRT547423	hsa-miR-642a-5p	PAR-CLIP	21572407
MIRT547421	hsa-miR-1261	PAR-CLIP	21572407
MIRT547419	hsa-miR-4755-5p	PAR-CLIP	21572407
MIRT547420	hsa-miR-5006-3p	PAR-CLIP	21572407
MIRT547418	hsa-miR-4446-5p	PAR-CLIP	21572407
MIRT571407	hsa-miR-3133	PAR-CLIP	20371350
MIRT021128	hsa-miR-186-5p	PAR-CLIP	20371350
MIRT571405	hsa-miR-452-5p	PAR-CLIP	20371350
MIRT571403	hsa-miR-4676-3p	PAR-CLIP	20371350
MIRT571404	hsa-miR-892c-3p	PAR-CLIP	20371350
MIRT571402	hsa-miR-6752-3p	PAR-CLIP	20371350
MIRT571400	hsa-miR-670-5p	PAR-CLIP	20371350
MIRT571401	hsa-miR-5089-3p	PAR-CLIP	20371350
MIRT547419	hsa-miR-4755-5p	PAR-CLIP	20371350
MIRT547420	hsa-miR-5006-3p	PAR-CLIP	20371350
MIRT547418	hsa-miR-4446-5p	PAR-CLIP	20371350
MIRT571399	hsa-miR-1324	PAR-CLIP	20371350
MIRT547436	hsa-miR-190b	PAR-CLIP	21572407
MIRT547435	hsa-miR-190a-5p	PAR-CLIP	21572407
MIRT547434	hsa-miR-1245a	PAR-CLIP	21572407
MIRT547433	hsa-miR-8079	PAR-CLIP	21572407
MIRT547432	hsa-miR-8062	PAR-CLIP	21572407
MIRT547431	hsa-miR-8076	PAR-CLIP	21572407
MIRT547430	hsa-miR-1246	PAR-CLIP	21572407
MIRT547429	hsa-miR-3689a-5p	PAR-CLIP	21572407
MIRT547428	hsa-miR-3689b-5p	PAR-CLIP	21572407
MIRT547427	hsa-miR-3689e	PAR-CLIP	21572407
MIRT547426	hsa-miR-3689f	PAR-CLIP	21572407
MIRT547425	hsa-miR-3606-5p	PAR-CLIP	21572407
MIRT547424	hsa-miR-921	PAR-CLIP	21572407
MIRT547422	hsa-miR-3924	PAR-CLIP	21572407
MIRT547423	hsa-miR-642a-5p	PAR-CLIP	21572407
MIRT547421	hsa-miR-1261	PAR-CLIP	21572407
MIRT547436	hsa-miR-190b	PAR-CLIP	21572407
MIRT547435	hsa-miR-190a-5p	PAR-CLIP	21572407
MIRT547434	hsa-miR-1245a	PAR-CLIP	21572407
MIRT547433	hsa-miR-8079	PAR-CLIP	21572407
MIRT547432	hsa-miR-8062	PAR-CLIP	21572407
MIRT547431	hsa-miR-8076	PAR-CLIP	21572407
MIRT547430	hsa-miR-1246	PAR-CLIP	21572407
MIRT547429	hsa-miR-3689a-5p	PAR-CLIP	21572407
MIRT547428	hsa-miR-3689b-5p	PAR-CLIP	21572407
MIRT547427	hsa-miR-3689e	PAR-CLIP	21572407
MIRT547426	hsa-miR-3689f	PAR-CLIP	21572407
MIRT547425	hsa-miR-3606-5p	PAR-CLIP	21572407
MIRT547424	hsa-miR-921	PAR-CLIP	21572407
MIRT547422	hsa-miR-3924	PAR-CLIP	21572407
MIRT547423	hsa-miR-642a-5p	PAR-CLIP	21572407
MIRT547421	hsa-miR-1261	PAR-CLIP	21572407
MIRT547419	hsa-miR-4755-5p	PAR-CLIP	21572407
MIRT547420	hsa-miR-5006-3p	PAR-CLIP	21572407
MIRT547418	hsa-miR-4446-5p	PAR-CLIP	21572407
MIRT1141753	hsa-miR-101	CLIP-seq
MIRT1141754	hsa-miR-139-5p	CLIP-seq
MIRT1141755	hsa-miR-144	CLIP-seq
MIRT1141756	hsa-miR-186	CLIP-seq
MIRT1141757	hsa-miR-3646	CLIP-seq
MIRT1141758	hsa-miR-3686	CLIP-seq
MIRT1141759	hsa-miR-425	CLIP-seq
MIRT1141760	hsa-miR-4272	CLIP-seq
MIRT1141761	hsa-miR-4328	CLIP-seq
MIRT1141762	hsa-miR-4477b	CLIP-seq
MIRT1141763	hsa-miR-452	CLIP-seq
MIRT1141764	hsa-miR-4742-3p	CLIP-seq
MIRT1141765	hsa-miR-4778-5p	CLIP-seq
MIRT1141766	hsa-miR-511	CLIP-seq
MIRT1141767	hsa-miR-642b	CLIP-seq
MIRT1141768	hsa-miR-670	CLIP-seq
MIRT2040293	hsa-miR-1183	CLIP-seq
MIRT2040294	hsa-miR-1272	CLIP-seq
MIRT2040295	hsa-miR-1305	CLIP-seq
MIRT2040296	hsa-miR-1322	CLIP-seq
MIRT2040297	hsa-miR-4279	CLIP-seq
MIRT2040298	hsa-miR-4517	CLIP-seq
MIRT2040299	hsa-miR-4693-5p	CLIP-seq
MIRT1141764	hsa-miR-4742-3p	CLIP-seq
MIRT1141765	hsa-miR-4778-5p	CLIP-seq
MIRT2040300	hsa-miR-590-3p	CLIP-seq
MIRT1141767	hsa-miR-642b	CLIP-seq
MIRT1141753	hsa-miR-101	CLIP-seq
MIRT2270059	hsa-miR-105	CLIP-seq
MIRT2270060	hsa-miR-1243	CLIP-seq
MIRT2270061	hsa-miR-1245	CLIP-seq
MIRT2270062	hsa-miR-1266	CLIP-seq
MIRT2040295	hsa-miR-1305	CLIP-seq
MIRT1141754	hsa-miR-139-5p	CLIP-seq
MIRT1141755	hsa-miR-144	CLIP-seq
MIRT1141756	hsa-miR-186	CLIP-seq
MIRT2270063	hsa-miR-190	CLIP-seq
MIRT2270064	hsa-miR-3140-3p	CLIP-seq
MIRT2270065	hsa-miR-3163	CLIP-seq
MIRT2270066	hsa-miR-335	CLIP-seq
MIRT2270067	hsa-miR-340	CLIP-seq
MIRT2270068	hsa-miR-34a	CLIP-seq
MIRT2270069	hsa-miR-34c-5p	CLIP-seq
MIRT2270070	hsa-miR-3606	CLIP-seq
MIRT2270071	hsa-miR-3622a-3p	CLIP-seq
MIRT2270072	hsa-miR-3622b-3p	CLIP-seq
MIRT2270073	hsa-miR-3662	CLIP-seq
MIRT2270074	hsa-miR-3664-3p	CLIP-seq
MIRT2270075	hsa-miR-3689b	CLIP-seq
MIRT2270076	hsa-miR-421	CLIP-seq
MIRT1141761	hsa-miR-4328	CLIP-seq
MIRT2270077	hsa-miR-449a	CLIP-seq
MIRT2270078	hsa-miR-449b	CLIP-seq
MIRT2270079	hsa-miR-4518	CLIP-seq
MIRT1141763	hsa-miR-452	CLIP-seq
MIRT2040299	hsa-miR-4693-5p	CLIP-seq
MIRT2270080	hsa-miR-4703-3p	CLIP-seq
MIRT2270081	hsa-miR-4709-5p	CLIP-seq
MIRT2270082	hsa-miR-4773	CLIP-seq
MIRT2270083	hsa-miR-555	CLIP-seq
MIRT1141767	hsa-miR-642b	CLIP-seq
MIRT1141768	hsa-miR-670	CLIP-seq
MIRT2270084	hsa-miR-873	CLIP-seq
MIRT2270085	hsa-miR-891b	CLIP-seq
MIRT1141753	hsa-miR-101	CLIP-seq
MIRT2270061	hsa-miR-1245	CLIP-seq
MIRT2040294	hsa-miR-1272	CLIP-seq
MIRT2040295	hsa-miR-1305	CLIP-seq
MIRT2040296	hsa-miR-1322	CLIP-seq
MIRT2569096	hsa-miR-1343	CLIP-seq
MIRT1141754	hsa-miR-139-5p	CLIP-seq
MIRT2569097	hsa-miR-140-5p	CLIP-seq
MIRT1141755	hsa-miR-144	CLIP-seq
MIRT1141756	hsa-miR-186	CLIP-seq
MIRT2270063	hsa-miR-190	CLIP-seq
MIRT2569098	hsa-miR-199a-5p	CLIP-seq
MIRT2569099	hsa-miR-199b-5p	CLIP-seq
MIRT2569100	hsa-miR-2110	CLIP-seq
MIRT2569101	hsa-miR-3119	CLIP-seq
MIRT2569102	hsa-miR-3125	CLIP-seq
MIRT2270064	hsa-miR-3140-3p	CLIP-seq
MIRT2270070	hsa-miR-3606	CLIP-seq
MIRT2569103	hsa-miR-3613-3p	CLIP-seq
MIRT2270071	hsa-miR-3622a-3p	CLIP-seq
MIRT2270072	hsa-miR-3622b-3p	CLIP-seq
MIRT2569104	hsa-miR-3653	CLIP-seq
MIRT2270073	hsa-miR-3662	CLIP-seq
MIRT2569105	hsa-miR-3677-5p	CLIP-seq
MIRT1141758	hsa-miR-3686	CLIP-seq
MIRT2270075	hsa-miR-3689b	CLIP-seq
MIRT2569106	hsa-miR-3916	CLIP-seq
MIRT2569107	hsa-miR-3938	CLIP-seq
MIRT2569108	hsa-miR-409-5p	CLIP-seq
MIRT2270076	hsa-miR-421	CLIP-seq
MIRT2569109	hsa-miR-4257	CLIP-seq
MIRT2569110	hsa-miR-4263	CLIP-seq
MIRT2569111	hsa-miR-4271	CLIP-seq
MIRT1141760	hsa-miR-4272	CLIP-seq
MIRT2569112	hsa-miR-4282	CLIP-seq
MIRT2569113	hsa-miR-4422	CLIP-seq
MIRT2569114	hsa-miR-4471	CLIP-seq
MIRT2569115	hsa-miR-4476	CLIP-seq
MIRT2040298	hsa-miR-4517	CLIP-seq
MIRT1141763	hsa-miR-452	CLIP-seq
MIRT2569116	hsa-miR-4645-3p	CLIP-seq
MIRT2569117	hsa-miR-4666-3p	CLIP-seq
MIRT2569118	hsa-miR-4667-5p	CLIP-seq
MIRT2569119	hsa-miR-4676-5p	CLIP-seq
MIRT2569120	hsa-miR-4699-3p	CLIP-seq
MIRT2569121	hsa-miR-4700-5p	CLIP-seq
MIRT2270080	hsa-miR-4703-3p	CLIP-seq
MIRT2569122	hsa-miR-4704-3p	CLIP-seq
MIRT2270081	hsa-miR-4709-5p	CLIP-seq
MIRT2569123	hsa-miR-4725-3p	CLIP-seq
MIRT1141764	hsa-miR-4742-3p	CLIP-seq
MIRT2270082	hsa-miR-4773	CLIP-seq
MIRT1141765	hsa-miR-4778-5p	CLIP-seq
MIRT2569124	hsa-miR-4796-3p	CLIP-seq
MIRT2569125	hsa-miR-4799-5p	CLIP-seq
MIRT2569126	hsa-miR-499-3p	CLIP-seq
MIRT2569127	hsa-miR-499a-3p	CLIP-seq
MIRT1141766	hsa-miR-511	CLIP-seq
MIRT2569128	hsa-miR-513a-3p	CLIP-seq
MIRT2569129	hsa-miR-520d-5p	CLIP-seq
MIRT2569130	hsa-miR-524-5p	CLIP-seq
MIRT2569131	hsa-miR-548a-3p	CLIP-seq
MIRT2569132	hsa-miR-548c-3p	CLIP-seq
MIRT2569133	hsa-miR-548e	CLIP-seq
MIRT2569134	hsa-miR-548f	CLIP-seq
MIRT2569135	hsa-miR-548n	CLIP-seq
MIRT2569136	hsa-miR-548t	CLIP-seq
MIRT2270083	hsa-miR-555	CLIP-seq
MIRT2569137	hsa-miR-556-3p	CLIP-seq
MIRT2569138	hsa-miR-568	CLIP-seq
MIRT2569139	hsa-miR-575	CLIP-seq
MIRT2569140	hsa-miR-576-5p	CLIP-seq
MIRT2569141	hsa-miR-619	CLIP-seq
MIRT1141767	hsa-miR-642b	CLIP-seq
MIRT1141768	hsa-miR-670	CLIP-seq
MIRT2569142	hsa-miR-9	CLIP-seq
MIRT1141753	hsa-miR-101	CLIP-seq
MIRT2040294	hsa-miR-1272	CLIP-seq
MIRT2040295	hsa-miR-1305	CLIP-seq
MIRT2040296	hsa-miR-1322	CLIP-seq
MIRT2569096	hsa-miR-1343	CLIP-seq
MIRT1141754	hsa-miR-139-5p	CLIP-seq
MIRT2569097	hsa-miR-140-5p	CLIP-seq
MIRT1141755	hsa-miR-144	CLIP-seq
MIRT1141756	hsa-miR-186	CLIP-seq
MIRT2569098	hsa-miR-199a-5p	CLIP-seq
MIRT2569099	hsa-miR-199b-5p	CLIP-seq
MIRT2569100	hsa-miR-2110	CLIP-seq
MIRT2569101	hsa-miR-3119	CLIP-seq
MIRT2569102	hsa-miR-3125	CLIP-seq
MIRT2270064	hsa-miR-3140-3p	CLIP-seq
MIRT2684801	hsa-miR-3179	CLIP-seq
MIRT2569103	hsa-miR-3613-3p	CLIP-seq
MIRT2270071	hsa-miR-3622a-3p	CLIP-seq
MIRT2270072	hsa-miR-3622b-3p	CLIP-seq
MIRT2569104	hsa-miR-3653	CLIP-seq
MIRT2270073	hsa-miR-3662	CLIP-seq
MIRT1141758	hsa-miR-3686	CLIP-seq
MIRT2569106	hsa-miR-3916	CLIP-seq
MIRT2569107	hsa-miR-3938	CLIP-seq
MIRT2569108	hsa-miR-409-5p	CLIP-seq
MIRT2270076	hsa-miR-421	CLIP-seq
MIRT2569109	hsa-miR-4257	CLIP-seq
MIRT2569111	hsa-miR-4271	CLIP-seq
MIRT1141760	hsa-miR-4272	CLIP-seq
MIRT2569112	hsa-miR-4282	CLIP-seq
MIRT2569113	hsa-miR-4422	CLIP-seq
MIRT2569114	hsa-miR-4471	CLIP-seq
MIRT2569115	hsa-miR-4476	CLIP-seq
MIRT2040298	hsa-miR-4517	CLIP-seq
MIRT1141763	hsa-miR-452	CLIP-seq
MIRT2569116	hsa-miR-4645-3p	CLIP-seq
MIRT2569117	hsa-miR-4666-3p	CLIP-seq
MIRT2569118	hsa-miR-4667-5p	CLIP-seq
MIRT2569119	hsa-miR-4676-5p	CLIP-seq
MIRT2569121	hsa-miR-4700-5p	CLIP-seq
MIRT2270080	hsa-miR-4703-3p	CLIP-seq
MIRT2569122	hsa-miR-4704-3p	CLIP-seq
MIRT2270081	hsa-miR-4709-5p	CLIP-seq
MIRT2569123	hsa-miR-4725-3p	CLIP-seq
MIRT1141764	hsa-miR-4742-3p	CLIP-seq
MIRT2270082	hsa-miR-4773	CLIP-seq
MIRT1141765	hsa-miR-4778-5p	CLIP-seq
MIRT2569124	hsa-miR-4796-3p	CLIP-seq
MIRT2569126	hsa-miR-499-3p	CLIP-seq
MIRT2569127	hsa-miR-499a-3p	CLIP-seq
MIRT1141766	hsa-miR-511	CLIP-seq
MIRT2569128	hsa-miR-513a-3p	CLIP-seq
MIRT2569131	hsa-miR-548a-3p	CLIP-seq
MIRT2569132	hsa-miR-548c-3p	CLIP-seq
MIRT2569133	hsa-miR-548e	CLIP-seq
MIRT2569134	hsa-miR-548f	CLIP-seq
MIRT2569135	hsa-miR-548n	CLIP-seq
MIRT2569136	hsa-miR-548t	CLIP-seq
MIRT2270083	hsa-miR-555	CLIP-seq
MIRT2569137	hsa-miR-556-3p	CLIP-seq
MIRT2569138	hsa-miR-568	CLIP-seq
MIRT2569139	hsa-miR-575	CLIP-seq
MIRT2569141	hsa-miR-619	CLIP-seq
MIRT1141767	hsa-miR-642b	CLIP-seq
MIRT1141768	hsa-miR-670	CLIP-seq
MIRT2569142	hsa-miR-9	CLIP-seq

Show/Hide all(25)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003712	Function	Transcription coregulator activity	IBA
GO:0003712	Function	Transcription coregulator activity	IDA	10882111
GO:0003712	Function	Transcription coregulator activity	IEA
GO:0003713	Function	Transcription coactivator activity	IDA
GO:0003713	Function	Transcription coactivator activity	NAS	10235266
GO:0005515	Function	Protein binding	IPI	14638676, 15175163, 16189514, 17438371, 21293490, 21729782, 24882805, 24981860, 25281560, 25416956, 26496610, 28514442, 32296183, 33961781, 35271311
GO:0005634	Component	Nucleus	IDA	10235267, 24882805
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IEA
GO:0006366	Process	Transcription by RNA polymerase II	IDA	10882111
GO:0016020	Component	Membrane	HDA	19946888
GO:0016592	Component	Mediator complex	IDA	10882111, 14638676
GO:0016592	Component	Mediator complex	IEA
GO:0032968	Process	Positive regulation of transcription elongation by RNA polymerase II	NAS	11559591
GO:0042809	Function	Nuclear vitamin D receptor binding	NAS	10235266
GO:0045893	Process	Positive regulation of DNA-templated transcription	IDA
GO:0046966	Function	Nuclear thyroid hormone receptor binding	IDA
GO:0051123	Process	RNA polymerase II preinitiation complex assembly	NAS	11559591
GO:0060261	Process	Positive regulation of transcription initiation by RNA polymerase II	IDA
GO:0060261	Process	Positive regulation of transcription initiation by RNA polymerase II	NAS	11559591
GO:0070847	Component	Core mediator complex	IBA
GO:0070847	Component	Core mediator complex	IPI	24882805

MIM	HGNC	e!Ensembl
605718	17903	ENSG00000136146

Protein

UniProt ID

Q9NPJ6

Protein name

Mediator of RNA polymerase II transcription subunit 4 (Activator-recruited cofactor 36 kDa component) (ARC36) (Mediator complex subunit 4) (TRAP/SMCC/PC2 subunit p36 subunit) (Vitamin D3 receptor-interacting protein complex 36 kDa component) (DRIP36)

Protein function

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RN

PDB

7EMF , 7ENA , 7ENC , 7ENJ , 7LBM , 7NVR , 8GXQ , 8GXS , 8T9D , 8TQW , 8TRH

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF10018	Med4	63 → 206	Vitamin-D-receptor interacting Mediator subunit 4	Family

Sequence

MAASSSGEKEKERLGGGLGVAGGNSTRERLLSALEDLEVLSRELIEMLAISRNQKLLQAG
EENQVLELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQI
LATAVYQAKEKLKSIEKARKGAISSEEIIKYAHRISASNAVCAPLTWVPGDPRRPYPTDL
EMRSGLLGQMNNPSTNGVNGHLPGDALAAGRLPDVLAPQYPWQSNDMSMNMLPPNHSSDF
LLEPPGHNKENEDDVEIMSTDSSSSSSESD

Sequence length

270

Interactions

View interactions

	KEGG		Reactome
	Thyroid hormone signaling pathway		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation

Show/Hide Unknown Diseases (1)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Oligodendroglioma	Oligodendroglioma	N/A	N/A	GWAS

Show/Hide Text Mining Associations (9)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenocarcinoma of Lung	Associate	32533823
Carcinogenesis	Associate	31695025
Carcinoma Non Small Cell Lung	Associate	31638248
Constipation	Associate	21505449
Heart Defects Congenital	Associate	21505449
Lymphatic Metastasis	Associate	31638248
Neoplasms	Inhibit	31695025
Retinoblastoma	Associate	21505449
Uterine Cervical Neoplasms	Associate	19911042

MED4 (mediator complex subunit 4)