Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
29079
|
Gene name
Gene Name - the full gene name approved by the HGNC.
|
Mediator complex subunit 4 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
MED4 |
Synonyms (NCBI Gene)
Gene synonyms aliases
|
ARC36, DRIP36, HSPC126, TRAP36, VDRIP |
Chromosome
Chromosome number
|
13 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
13q14.2 |
Summary
Summary of gene provided in NCBI Entrez Gene.
|
This gene encodes a component of the Mediator complex. The Mediator complex interacts with DNA-binding gene-specific transcription factors to modulate transcription by RNA polymerase II. Alternatively spliced transcript variants encoding multiple isoforms |
UniProt ID |
Q9NPJ6
|
Protein name |
Mediator of RNA polymerase II transcription subunit 4 (Activator-recruited cofactor 36 kDa component) (ARC36) (Mediator complex subunit 4) (TRAP/SMCC/PC2 subunit p36 subunit) (Vitamin D3 receptor-interacting protein complex 36 kDa component) (DRIP36) |
Protein function |
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RN |
PDB |
7EMF
,
7ENA
,
7ENC
,
7ENJ
,
7LBM
,
7NVR
,
8GXQ
,
8GXS
,
8T9D
,
8TQW
,
8TRH
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF10018
|
Med4 |
63 → 206 |
Vitamin-D-receptor interacting Mediator subunit 4 |
Family |
|
Sequence |
|
Sequence length |
270 |
Interactions |
View interactions
|