Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
29015
Gene name Gene Name - the full gene name approved by the HGNC.
Solute carrier family 43 member 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
SLC43A3
Synonyms (NCBI Gene) Gene synonyms aliases
EEG1, ENBT1, FOAP-13, PRO1659, SEEEG-1
Chromosome Chromosome number
11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
11q12.1
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT022191 hsa-miR-124-3p Microarray 18668037
MIRT691680 hsa-miR-548a-5p HITS-CLIP 23313552
MIRT691679 hsa-miR-548ab HITS-CLIP 23313552
MIRT691678 hsa-miR-548ad-5p HITS-CLIP 23313552
MIRT691677 hsa-miR-548ae-5p HITS-CLIP 23313552
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32814053
GO:0005886 Component Plasma membrane IEA
GO:0006869 Process Lipid transport IEA
GO:0015207 Function Adenine transmembrane transporter activity IDA 26455426, 30910793, 32339528
GO:0015208 Function Guanine transmembrane transporter activity IDA 26455426
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
618034 17466 ENSG00000134802
Protein
UniProt ID Q8NBI5
Protein name Equilibrative nucleobase transporter 1 (Protein FOAP-13) (Solute carrier family 43 member 3)
Protein function Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobases such as adenine, guanine and hypoxanthine (PubMed:26455426, PubMed:32339528). May regulate fatty acid (FA)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07690 MFS_1 12 441 Major Facilitator Superfamily Family
Tissue specificity TISSUE SPECIFICITY: Widely expressed with highest levels in the liver and lung, followed by the pancreas (PubMed:26455426). Highly expressed in macrophages (Ref.1). {ECO:0000269|PubMed:26455426, ECO:0000269|Ref.1}.
Sequence
Sequence length 491
Interactions View interactions
<
Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Crohn Disease Crohn's disease N/A N/A GWAS
Gout Gout N/A N/A GWAS
Hypothyroidism Hypothyroidism N/A N/A GWAS
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Atherosclerosis Associate 21827714