ABR (ABR activator of RhoGEF and GTPase)

Gene

• Entrez ID: 29
• Gene name: ABR activator of RhoGEF and GTPase
• Gene symbol: ABR
• Synonyms (NCBI Gene): MDB
• Chromosome: 17
• Chromosome location: 17p13.3
• Summary: This gene encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. The protein encoded by this gene contains a GTPase-activating protein domain, a domain found in members of the Rho family of

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT050728	hsa-miR-18a-5p	CLASH	23622248
MIRT040702	hsa-miR-92b-3p	CLASH	23622248
MIRT038901	hsa-miR-93-3p	CLASH	23622248
MIRT037178	hsa-miR-877-3p	CLASH	23622248
MIRT733077	hsa-miR-762	Luciferase reporter assay, Western blotting, qRT-PCR	31823748
MIRT761001	hsa-miR-1324	CLIP-seq
MIRT761002	hsa-miR-199a-5p	CLIP-seq
MIRT761003	hsa-miR-199b-5p	CLIP-seq
MIRT761004	hsa-miR-202	CLIP-seq
MIRT761005	hsa-miR-214	CLIP-seq
MIRT761006	hsa-miR-3121-3p	CLIP-seq
MIRT761007	hsa-miR-3202	CLIP-seq
MIRT761008	hsa-miR-3616-3p	CLIP-seq
MIRT761009	hsa-miR-3619-5p	CLIP-seq
MIRT761010	hsa-miR-3689d	CLIP-seq
MIRT761011	hsa-miR-3713	CLIP-seq
MIRT761012	hsa-miR-4436b-3p	CLIP-seq
MIRT761013	hsa-miR-4459	CLIP-seq
MIRT761014	hsa-miR-4471	CLIP-seq
MIRT761015	hsa-miR-4654	CLIP-seq
MIRT761016	hsa-miR-4711-5p	CLIP-seq
MIRT761017	hsa-miR-4722-5p	CLIP-seq
MIRT761018	hsa-miR-4747-5p	CLIP-seq
MIRT761019	hsa-miR-4769-5p	CLIP-seq
MIRT761020	hsa-miR-4773	CLIP-seq
MIRT761021	hsa-miR-4802-5p	CLIP-seq
MIRT761022	hsa-miR-761	CLIP-seq
MIRT761023	hsa-miR-1270	CLIP-seq
MIRT761024	hsa-miR-1281	CLIP-seq
MIRT761025	hsa-miR-1285	CLIP-seq
MIRT761026	hsa-miR-139-3p	CLIP-seq
MIRT761027	hsa-miR-18a	CLIP-seq
MIRT761028	hsa-miR-18b	CLIP-seq
MIRT761029	hsa-miR-191	CLIP-seq
MIRT761030	hsa-miR-3180-5p	CLIP-seq
MIRT761031	hsa-miR-3187-5p	CLIP-seq
MIRT761032	hsa-miR-361-3p	CLIP-seq
MIRT761033	hsa-miR-3647-3p	CLIP-seq
MIRT761034	hsa-miR-378g	CLIP-seq
MIRT761035	hsa-miR-4486	CLIP-seq
MIRT761036	hsa-miR-4683	CLIP-seq
MIRT761037	hsa-miR-4735-3p	CLIP-seq
MIRT761038	hsa-miR-4761-5p	CLIP-seq
MIRT761039	hsa-miR-4795-5p	CLIP-seq
MIRT761040	hsa-miR-520a-5p	CLIP-seq
MIRT761041	hsa-miR-525-5p	CLIP-seq
MIRT761042	hsa-miR-612	CLIP-seq
MIRT761043	hsa-miR-620	CLIP-seq
MIRT761044	hsa-miR-622	CLIP-seq
MIRT761045	hsa-miR-624	CLIP-seq
MIRT761024	hsa-miR-1281	CLIP-seq
MIRT761046	hsa-miR-299-5p	CLIP-seq
MIRT761032	hsa-miR-361-3p	CLIP-seq
MIRT761047	hsa-miR-369-3p	CLIP-seq
MIRT761048	hsa-miR-374a	CLIP-seq
MIRT761049	hsa-miR-374b	CLIP-seq
MIRT761050	hsa-miR-433	CLIP-seq
MIRT761051	hsa-miR-4477a	CLIP-seq
MIRT761052	hsa-miR-499-3p	CLIP-seq
MIRT761053	hsa-miR-499a-3p	CLIP-seq
MIRT761054	hsa-miR-664	CLIP-seq
MIRT1924324	hsa-miR-106a	CLIP-seq
MIRT1924325	hsa-miR-106b	CLIP-seq
MIRT1924326	hsa-miR-1207-5p	CLIP-seq
MIRT1924327	hsa-miR-1238	CLIP-seq
MIRT1924328	hsa-miR-1245b-5p	CLIP-seq
MIRT1924329	hsa-miR-125a-5p	CLIP-seq
MIRT1924330	hsa-miR-125b	CLIP-seq
MIRT761025	hsa-miR-1285	CLIP-seq
MIRT1924331	hsa-miR-1287	CLIP-seq
MIRT1924332	hsa-miR-1587	CLIP-seq
MIRT1924333	hsa-miR-17	CLIP-seq
MIRT1924334	hsa-miR-1913	CLIP-seq
MIRT1924335	hsa-miR-1915	CLIP-seq
MIRT761004	hsa-miR-202	CLIP-seq
MIRT1924336	hsa-miR-20a	CLIP-seq
MIRT1924337	hsa-miR-20b	CLIP-seq
MIRT1924338	hsa-miR-219-1-3p	CLIP-seq
MIRT1924339	hsa-miR-302a	CLIP-seq
MIRT1924340	hsa-miR-302b	CLIP-seq
MIRT1924341	hsa-miR-302c	CLIP-seq
MIRT1924342	hsa-miR-302d	CLIP-seq
MIRT1924343	hsa-miR-302e	CLIP-seq
MIRT1924344	hsa-miR-3064-5p	CLIP-seq
MIRT1924345	hsa-miR-3135b	CLIP-seq
MIRT1924346	hsa-miR-3142	CLIP-seq
MIRT761031	hsa-miR-3187-5p	CLIP-seq
MIRT1924347	hsa-miR-3189-3p	CLIP-seq
MIRT761007	hsa-miR-3202	CLIP-seq
MIRT1924348	hsa-miR-324-3p	CLIP-seq
MIRT1924349	hsa-miR-326	CLIP-seq
MIRT1924350	hsa-miR-330-5p	CLIP-seq
MIRT1924351	hsa-miR-340	CLIP-seq
MIRT1924352	hsa-miR-3614-3p	CLIP-seq
MIRT761008	hsa-miR-3616-3p	CLIP-seq
MIRT1924353	hsa-miR-3622a-3p	CLIP-seq
MIRT1924354	hsa-miR-3622b-3p	CLIP-seq
MIRT1924355	hsa-miR-3649	CLIP-seq
MIRT1924356	hsa-miR-3652	CLIP-seq
MIRT1924357	hsa-miR-372	CLIP-seq
MIRT1924358	hsa-miR-373	CLIP-seq
MIRT1924359	hsa-miR-378	CLIP-seq
MIRT1924360	hsa-miR-378b	CLIP-seq
MIRT1924361	hsa-miR-378c	CLIP-seq
MIRT1924362	hsa-miR-378d	CLIP-seq
MIRT1924363	hsa-miR-378e	CLIP-seq
MIRT1924364	hsa-miR-378f	CLIP-seq
MIRT1924365	hsa-miR-378h	CLIP-seq
MIRT1924366	hsa-miR-378i	CLIP-seq
MIRT1924367	hsa-miR-3918	CLIP-seq
MIRT1924368	hsa-miR-3922-5p	CLIP-seq
MIRT1924369	hsa-miR-3937	CLIP-seq
MIRT1924370	hsa-miR-422a	CLIP-seq
MIRT1924371	hsa-miR-4286	CLIP-seq
MIRT1924372	hsa-miR-4293	CLIP-seq
MIRT1924373	hsa-miR-4319	CLIP-seq
MIRT1924374	hsa-miR-4430	CLIP-seq
MIRT761012	hsa-miR-4436b-3p	CLIP-seq
MIRT761013	hsa-miR-4459	CLIP-seq
MIRT1924375	hsa-miR-4476	CLIP-seq
MIRT761051	hsa-miR-4477a	CLIP-seq
MIRT1924376	hsa-miR-4492	CLIP-seq
MIRT1924377	hsa-miR-4498	CLIP-seq
MIRT1924378	hsa-miR-4505	CLIP-seq
MIRT1924379	hsa-miR-4512	CLIP-seq
MIRT1924380	hsa-miR-4514	CLIP-seq
MIRT1924381	hsa-miR-4517	CLIP-seq
MIRT1924382	hsa-miR-4533	CLIP-seq
MIRT1924383	hsa-miR-4535	CLIP-seq
MIRT1924384	hsa-miR-4639-3p	CLIP-seq
MIRT1924385	hsa-miR-4640-5p	CLIP-seq
MIRT1924386	hsa-miR-4645-5p	CLIP-seq
MIRT1924387	hsa-miR-4646-5p	CLIP-seq
MIRT1924388	hsa-miR-4651	CLIP-seq
MIRT761015	hsa-miR-4654	CLIP-seq
MIRT1924389	hsa-miR-4656	CLIP-seq
MIRT1924390	hsa-miR-4667-5p	CLIP-seq
MIRT1924391	hsa-miR-4673	CLIP-seq
MIRT1924392	hsa-miR-4674	CLIP-seq
MIRT1924393	hsa-miR-4675	CLIP-seq
MIRT1924394	hsa-miR-4677-3p	CLIP-seq
MIRT1924395	hsa-miR-4682	CLIP-seq
MIRT1924396	hsa-miR-4685-5p	CLIP-seq
MIRT1924397	hsa-miR-4690-3p	CLIP-seq
MIRT1924398	hsa-miR-4692	CLIP-seq
MIRT1924399	hsa-miR-4700-5p	CLIP-seq
MIRT1924400	hsa-miR-4717-5p	CLIP-seq
MIRT761017	hsa-miR-4722-5p	CLIP-seq
MIRT1924401	hsa-miR-4725-5p	CLIP-seq
MIRT1924402	hsa-miR-4726-5p	CLIP-seq
MIRT1924403	hsa-miR-4731-5p	CLIP-seq
MIRT1924404	hsa-miR-4741	CLIP-seq
MIRT761018	hsa-miR-4747-5p	CLIP-seq
MIRT1924405	hsa-miR-4753-5p	CLIP-seq
MIRT1924406	hsa-miR-4757-5p	CLIP-seq
MIRT1924407	hsa-miR-4763-3p	CLIP-seq
MIRT761019	hsa-miR-4769-5p	CLIP-seq
MIRT761020	hsa-miR-4773	CLIP-seq
MIRT1924408	hsa-miR-4776-5p	CLIP-seq
MIRT761021	hsa-miR-4802-5p	CLIP-seq
MIRT1924409	hsa-miR-498	CLIP-seq
MIRT1924410	hsa-miR-504	CLIP-seq
MIRT1924411	hsa-miR-510	CLIP-seq
MIRT1924412	hsa-miR-512-3p	CLIP-seq
MIRT1924413	hsa-miR-513a-5p	CLIP-seq
MIRT1924414	hsa-miR-519d	CLIP-seq
MIRT1924415	hsa-miR-520a-3p	CLIP-seq
MIRT1924416	hsa-miR-520b	CLIP-seq
MIRT1924417	hsa-miR-520c-3p	CLIP-seq
MIRT1924418	hsa-miR-520d-3p	CLIP-seq
MIRT1924419	hsa-miR-520e	CLIP-seq
MIRT1924420	hsa-miR-571	CLIP-seq
MIRT1924421	hsa-miR-608	CLIP-seq
MIRT761042	hsa-miR-612	CLIP-seq
MIRT1924422	hsa-miR-635	CLIP-seq
MIRT1924423	hsa-miR-637	CLIP-seq
MIRT1924424	hsa-miR-711	CLIP-seq
MIRT1924425	hsa-miR-765	CLIP-seq
MIRT1924426	hsa-miR-93	CLIP-seq
MIRT1924427	hsa-miR-940	CLIP-seq
MIRT1924334	hsa-miR-1913	CLIP-seq
MIRT1924338	hsa-miR-219-1-3p	CLIP-seq
MIRT1924345	hsa-miR-3135b	CLIP-seq
MIRT1924348	hsa-miR-324-3p	CLIP-seq
MIRT2165644	hsa-miR-346	CLIP-seq
MIRT2165645	hsa-miR-3659	CLIP-seq
MIRT1924371	hsa-miR-4286	CLIP-seq
MIRT2165646	hsa-miR-4288	CLIP-seq
MIRT1924380	hsa-miR-4514	CLIP-seq
MIRT2165647	hsa-miR-4658	CLIP-seq
MIRT1924395	hsa-miR-4682	CLIP-seq
MIRT1924398	hsa-miR-4692	CLIP-seq
MIRT2165648	hsa-miR-4711-3p	CLIP-seq
MIRT1924403	hsa-miR-4731-5p	CLIP-seq
MIRT2165649	hsa-miR-485-5p	CLIP-seq
MIRT1924420	hsa-miR-571	CLIP-seq
MIRT2165650	hsa-miR-574-5p	CLIP-seq
MIRT2165651	hsa-miR-632	CLIP-seq
MIRT2383789	hsa-miR-4691-3p	CLIP-seq
MIRT2441917	hsa-miR-370	CLIP-seq
MIRT2468097	hsa-miR-103b	CLIP-seq
MIRT1924326	hsa-miR-1207-5p	CLIP-seq
MIRT2468098	hsa-miR-1225-3p	CLIP-seq
MIRT2468099	hsa-miR-1227	CLIP-seq
MIRT2468100	hsa-miR-1229	CLIP-seq
MIRT2468101	hsa-miR-1237	CLIP-seq
MIRT2468102	hsa-miR-128	CLIP-seq
MIRT761025	hsa-miR-1285	CLIP-seq
MIRT2468103	hsa-miR-1301	CLIP-seq
MIRT2468104	hsa-miR-134	CLIP-seq
MIRT2468105	hsa-miR-149	CLIP-seq
MIRT2468106	hsa-miR-1538	CLIP-seq
MIRT1924334	hsa-miR-1913	CLIP-seq
MIRT2468107	hsa-miR-1976	CLIP-seq
MIRT2468108	hsa-miR-2114	CLIP-seq
MIRT2468109	hsa-miR-2117	CLIP-seq
MIRT761005	hsa-miR-214	CLIP-seq
MIRT2468110	hsa-miR-3064-3p	CLIP-seq
MIRT1924344	hsa-miR-3064-5p	CLIP-seq
MIRT2468111	hsa-miR-3118	CLIP-seq
MIRT761006	hsa-miR-3121-3p	CLIP-seq
MIRT2468112	hsa-miR-3121-5p	CLIP-seq
MIRT2468113	hsa-miR-3122	CLIP-seq
MIRT2468114	hsa-miR-3127-3p	CLIP-seq
MIRT2468115	hsa-miR-3152-5p	CLIP-seq
MIRT2468116	hsa-miR-3181	CLIP-seq
MIRT2468117	hsa-miR-3182	CLIP-seq
MIRT761031	hsa-miR-3187-5p	CLIP-seq
MIRT1924347	hsa-miR-3189-3p	CLIP-seq
MIRT761007	hsa-miR-3202	CLIP-seq
MIRT1924348	hsa-miR-324-3p	CLIP-seq
MIRT1924349	hsa-miR-326	CLIP-seq
MIRT2468118	hsa-miR-329	CLIP-seq
MIRT1924350	hsa-miR-330-5p	CLIP-seq
MIRT2468119	hsa-miR-331-3p	CLIP-seq
MIRT2468120	hsa-miR-33a	CLIP-seq
MIRT2468121	hsa-miR-33b	CLIP-seq
MIRT1924351	hsa-miR-340	CLIP-seq
MIRT2468122	hsa-miR-345	CLIP-seq
MIRT1924352	hsa-miR-3614-3p	CLIP-seq
MIRT761009	hsa-miR-3619-5p	CLIP-seq
MIRT2468123	hsa-miR-3620	CLIP-seq
MIRT1924353	hsa-miR-3622a-3p	CLIP-seq
MIRT1924354	hsa-miR-3622b-3p	CLIP-seq
MIRT2468124	hsa-miR-362-3p	CLIP-seq
MIRT1924355	hsa-miR-3649	CLIP-seq
MIRT2468125	hsa-miR-3667-3p	CLIP-seq
MIRT2468126	hsa-miR-3689a-3p	CLIP-seq
MIRT2468127	hsa-miR-3689c	CLIP-seq
MIRT761010	hsa-miR-3689d	CLIP-seq
MIRT2441917	hsa-miR-370	CLIP-seq
MIRT2468128	hsa-miR-3913-5p	CLIP-seq
MIRT2468129	hsa-miR-3929	CLIP-seq
MIRT2468130	hsa-miR-3944-3p	CLIP-seq
MIRT2468131	hsa-miR-4254	CLIP-seq
MIRT2468132	hsa-miR-4260	CLIP-seq
MIRT2468133	hsa-miR-4269	CLIP-seq
MIRT2468134	hsa-miR-4273	CLIP-seq
MIRT2468135	hsa-miR-4281	CLIP-seq
MIRT2468136	hsa-miR-4283	CLIP-seq
MIRT2468137	hsa-miR-4284	CLIP-seq
MIRT1924371	hsa-miR-4286	CLIP-seq
MIRT2468138	hsa-miR-4292	CLIP-seq
MIRT1924372	hsa-miR-4293	CLIP-seq
MIRT2468139	hsa-miR-4297	CLIP-seq
MIRT2468140	hsa-miR-4300	CLIP-seq
MIRT2468141	hsa-miR-4308	CLIP-seq
MIRT2468142	hsa-miR-4419b	CLIP-seq
MIRT2468143	hsa-miR-4421	CLIP-seq
MIRT2468144	hsa-miR-4423-5p	CLIP-seq
MIRT2468145	hsa-miR-4453	CLIP-seq
MIRT2468146	hsa-miR-4455	CLIP-seq
MIRT761014	hsa-miR-4471	CLIP-seq
MIRT1924375	hsa-miR-4476	CLIP-seq
MIRT2468147	hsa-miR-4478	CLIP-seq
MIRT2468148	hsa-miR-4489	CLIP-seq
MIRT1924380	hsa-miR-4514	CLIP-seq
MIRT1924381	hsa-miR-4517	CLIP-seq
MIRT2468149	hsa-miR-4538	CLIP-seq
MIRT2468150	hsa-miR-4633-3p	CLIP-seq
MIRT1924384	hsa-miR-4639-3p	CLIP-seq
MIRT1924385	hsa-miR-4640-5p	CLIP-seq
MIRT1924386	hsa-miR-4645-5p	CLIP-seq
MIRT1924388	hsa-miR-4651	CLIP-seq
MIRT761015	hsa-miR-4654	CLIP-seq
MIRT2468151	hsa-miR-4660	CLIP-seq
MIRT1924390	hsa-miR-4667-5p	CLIP-seq
MIRT1924391	hsa-miR-4673	CLIP-seq
MIRT1924394	hsa-miR-4677-3p	CLIP-seq
MIRT2468152	hsa-miR-4686	CLIP-seq
MIRT1924397	hsa-miR-4690-3p	CLIP-seq
MIRT2468153	hsa-miR-4690-5p	CLIP-seq
MIRT1924398	hsa-miR-4692	CLIP-seq
MIRT1924399	hsa-miR-4700-5p	CLIP-seq
MIRT2468154	hsa-miR-4707-5p	CLIP-seq
MIRT2468155	hsa-miR-4722-3p	CLIP-seq
MIRT761017	hsa-miR-4722-5p	CLIP-seq
MIRT1924401	hsa-miR-4725-5p	CLIP-seq
MIRT1924402	hsa-miR-4726-5p	CLIP-seq
MIRT1924403	hsa-miR-4731-5p	CLIP-seq
MIRT2468156	hsa-miR-4745-3p	CLIP-seq
MIRT761018	hsa-miR-4747-5p	CLIP-seq
MIRT2468157	hsa-miR-4749-3p	CLIP-seq
MIRT2468158	hsa-miR-4750	CLIP-seq
MIRT2468159	hsa-miR-4755-3p	CLIP-seq
MIRT1924407	hsa-miR-4763-3p	CLIP-seq
MIRT2468160	hsa-miR-4768-3p	CLIP-seq
MIRT761019	hsa-miR-4769-5p	CLIP-seq
MIRT761020	hsa-miR-4773	CLIP-seq
MIRT2468161	hsa-miR-4794	CLIP-seq
MIRT2165649	hsa-miR-485-5p	CLIP-seq
MIRT2468162	hsa-miR-502-5p	CLIP-seq
MIRT1924410	hsa-miR-504	CLIP-seq
MIRT2468163	hsa-miR-5047	CLIP-seq
MIRT1924413	hsa-miR-513a-5p	CLIP-seq
MIRT2468164	hsa-miR-556-5p	CLIP-seq
MIRT2468165	hsa-miR-558	CLIP-seq
MIRT2468166	hsa-miR-582-3p	CLIP-seq
MIRT2468167	hsa-miR-596	CLIP-seq
MIRT1924421	hsa-miR-608	CLIP-seq
MIRT2468168	hsa-miR-609	CLIP-seq
MIRT761042	hsa-miR-612	CLIP-seq
MIRT2468169	hsa-miR-627	CLIP-seq
MIRT2468170	hsa-miR-629	CLIP-seq
MIRT1924423	hsa-miR-637	CLIP-seq
MIRT2468171	hsa-miR-645	CLIP-seq
MIRT2468172	hsa-miR-671-5p	CLIP-seq
MIRT761022	hsa-miR-761	CLIP-seq
MIRT2468173	hsa-miR-767-3p	CLIP-seq
MIRT2468174	hsa-miR-885-3p	CLIP-seq
MIRT2468175	hsa-miR-888	CLIP-seq
MIRT2468176	hsa-miR-892b	CLIP-seq
MIRT2468177	hsa-miR-920	CLIP-seq
MIRT2468178	hsa-miR-924	CLIP-seq
MIRT2468179	hsa-miR-936	CLIP-seq
MIRT2468180	hsa-miR-939	CLIP-seq
MIRT1924427	hsa-miR-940	CLIP-seq
MIRT2441917	hsa-miR-370	CLIP-seq
MIRT1924401	hsa-miR-4725-5p	CLIP-seq
MIRT1924410	hsa-miR-504	CLIP-seq
MIRT2441917	hsa-miR-370	CLIP-seq
MIRT1924401	hsa-miR-4725-5p	CLIP-seq
MIRT1924410	hsa-miR-504	CLIP-seq
MIRT1924326	hsa-miR-1207-5p	CLIP-seq
MIRT2468098	hsa-miR-1225-3p	CLIP-seq
MIRT2468099	hsa-miR-1227	CLIP-seq
MIRT2468101	hsa-miR-1237	CLIP-seq
MIRT2468102	hsa-miR-128	CLIP-seq
MIRT761025	hsa-miR-1285	CLIP-seq
MIRT2468104	hsa-miR-134	CLIP-seq
MIRT2468105	hsa-miR-149	CLIP-seq
MIRT2468106	hsa-miR-1538	CLIP-seq
MIRT1924334	hsa-miR-1913	CLIP-seq
MIRT2468107	hsa-miR-1976	CLIP-seq
MIRT2468108	hsa-miR-2114	CLIP-seq
MIRT2468110	hsa-miR-3064-3p	CLIP-seq
MIRT2468111	hsa-miR-3118	CLIP-seq
MIRT2468112	hsa-miR-3121-5p	CLIP-seq
MIRT2468114	hsa-miR-3127-3p	CLIP-seq
MIRT2468116	hsa-miR-3181	CLIP-seq
MIRT2468117	hsa-miR-3182	CLIP-seq
MIRT761031	hsa-miR-3187-5p	CLIP-seq
MIRT1924347	hsa-miR-3189-3p	CLIP-seq
MIRT1924348	hsa-miR-324-3p	CLIP-seq
MIRT1924349	hsa-miR-326	CLIP-seq
MIRT2468118	hsa-miR-329	CLIP-seq
MIRT1924350	hsa-miR-330-5p	CLIP-seq
MIRT2468119	hsa-miR-331-3p	CLIP-seq
MIRT2468120	hsa-miR-33a	CLIP-seq
MIRT2468121	hsa-miR-33b	CLIP-seq
MIRT1924351	hsa-miR-340	CLIP-seq
MIRT1924352	hsa-miR-3614-3p	CLIP-seq
MIRT2468123	hsa-miR-3620	CLIP-seq
MIRT2468124	hsa-miR-362-3p	CLIP-seq
MIRT1924355	hsa-miR-3649	CLIP-seq
MIRT2468125	hsa-miR-3667-3p	CLIP-seq
MIRT761010	hsa-miR-3689d	CLIP-seq
MIRT2441917	hsa-miR-370	CLIP-seq
MIRT2468129	hsa-miR-3929	CLIP-seq
MIRT2468130	hsa-miR-3944-3p	CLIP-seq
MIRT2468131	hsa-miR-4254	CLIP-seq
MIRT2468135	hsa-miR-4281	CLIP-seq
MIRT2468137	hsa-miR-4284	CLIP-seq
MIRT1924371	hsa-miR-4286	CLIP-seq
MIRT2468138	hsa-miR-4292	CLIP-seq
MIRT2468140	hsa-miR-4300	CLIP-seq
MIRT2468141	hsa-miR-4308	CLIP-seq
MIRT2468142	hsa-miR-4419b	CLIP-seq
MIRT2468143	hsa-miR-4421	CLIP-seq
MIRT2468146	hsa-miR-4455	CLIP-seq
MIRT2468147	hsa-miR-4478	CLIP-seq
MIRT1924380	hsa-miR-4514	CLIP-seq
MIRT1924381	hsa-miR-4517	CLIP-seq
MIRT2468150	hsa-miR-4633-3p	CLIP-seq
MIRT1924384	hsa-miR-4639-3p	CLIP-seq
MIRT1924386	hsa-miR-4645-5p	CLIP-seq
MIRT1924388	hsa-miR-4651	CLIP-seq
MIRT761015	hsa-miR-4654	CLIP-seq
MIRT1924390	hsa-miR-4667-5p	CLIP-seq
MIRT1924391	hsa-miR-4673	CLIP-seq
MIRT2468152	hsa-miR-4686	CLIP-seq
MIRT1924397	hsa-miR-4690-3p	CLIP-seq
MIRT1924398	hsa-miR-4692	CLIP-seq
MIRT1924399	hsa-miR-4700-5p	CLIP-seq
MIRT2468154	hsa-miR-4707-5p	CLIP-seq
MIRT2468155	hsa-miR-4722-3p	CLIP-seq
MIRT761017	hsa-miR-4722-5p	CLIP-seq
MIRT1924401	hsa-miR-4725-5p	CLIP-seq
MIRT1924403	hsa-miR-4731-5p	CLIP-seq
MIRT2468156	hsa-miR-4745-3p	CLIP-seq
MIRT2468157	hsa-miR-4749-3p	CLIP-seq
MIRT2468158	hsa-miR-4750	CLIP-seq
MIRT2468159	hsa-miR-4755-3p	CLIP-seq
MIRT1924407	hsa-miR-4763-3p	CLIP-seq
MIRT2468160	hsa-miR-4768-3p	CLIP-seq
MIRT761019	hsa-miR-4769-5p	CLIP-seq
MIRT2468161	hsa-miR-4794	CLIP-seq
MIRT2165649	hsa-miR-485-5p	CLIP-seq
MIRT2468162	hsa-miR-502-5p	CLIP-seq
MIRT1924410	hsa-miR-504	CLIP-seq
MIRT1924413	hsa-miR-513a-5p	CLIP-seq
MIRT2468164	hsa-miR-556-5p	CLIP-seq
MIRT2468165	hsa-miR-558	CLIP-seq
MIRT2468166	hsa-miR-582-3p	CLIP-seq
MIRT1924421	hsa-miR-608	CLIP-seq
MIRT2468168	hsa-miR-609	CLIP-seq
MIRT761042	hsa-miR-612	CLIP-seq
MIRT1924423	hsa-miR-637	CLIP-seq
MIRT2468171	hsa-miR-645	CLIP-seq
MIRT2468172	hsa-miR-671-5p	CLIP-seq
MIRT2468173	hsa-miR-767-3p	CLIP-seq
MIRT2468174	hsa-miR-885-3p	CLIP-seq
MIRT2468175	hsa-miR-888	CLIP-seq
MIRT2468176	hsa-miR-892b	CLIP-seq
MIRT2468177	hsa-miR-920	CLIP-seq
MIRT2468180	hsa-miR-939	CLIP-seq
MIRT1924427	hsa-miR-940	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IDA	7479768
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IEA
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	TAS
GO:0005096	Function	GTPase activator activity	IDA	7479768
GO:0005096	Function	GTPase activator activity	IEA
GO:0005096	Function	GTPase activator activity	TAS	8262969
GO:0005515	Function	Protein binding	IPI	20962234
GO:0005829	Component	Cytosol	TAS
GO:0007165	Process	Signal transduction	IEA
GO:0007264	Process	Small GTPase-mediated signal transduction	IEA
GO:0007264	Process	Small GTPase-mediated signal transduction	TAS	8262969
GO:0016020	Component	Membrane	HDA	19946888
GO:0016020	Component	Membrane	IBA
GO:0030424	Component	Axon	IEA
GO:0035556	Process	Intracellular signal transduction	IEA
GO:0042995	Component	Cell projection	IEA
GO:0043197	Component	Dendritic spine	IEA
GO:0045202	Component	Synapse	IEA
GO:0050804	Process	Modulation of chemical synaptic transmission	ISS
GO:0051056	Process	Regulation of small GTPase mediated signal transduction	TAS
GO:0090630	Process	Activation of GTPase activity	IDA	7479768
GO:0098685	Component	Schaffer collateral - CA1 synapse	ISS
GO:0098978	Component	Glutamatergic synapse	ISS

Other IDs

• MIM: 600365
• HGNC: 81
• e!Ensembl: ENSG00000159842

Protein

• UniProt ID: Q12979
• Protein name: Active breakpoint cluster region-related protein
• Protein function: Protein with a unique structure having two opposing regulatory activities toward small GTP-binding proteins. The C-terminus is a GTPase-activating protein domain which stimulates GTP hydrolysis by RAC1, RAC2 and CDC42. Accelerates the intrinsic
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00621	RhoGEF	95 → 282	RhoGEF domain	Domain
  PF00169	PH	302 → 459	PH domain	Domain
  PF00168	C2	504 → 610	C2 domain	Domain
  PF00620	RhoGAP	661 → 813	RhoGAP domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Highly enriched in the brain. Much weaker expression in heart, lung and muscle.
• Sequence:

  MEPLSHRGLPRLSWIDTLYSNFSYGTDEYDGEGNEEQKGPPEGSETMPYIDESPTMSPQL
  SARSQGGGDGVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEIYINQLEALLLPMKPL
  KATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQ
  LGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPI
  DRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKGETR
  QLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSP
  EESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLL
  NSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCF
  KLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKT
  RVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQLDP
  QTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERSKV
  PYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGT
  LKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLK
  RVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQH
  PPISFAELKRNTLYFSTDV

• Sequence length: 859

Pathways

Reactome:

NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events

Associated diseases

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
ABR-related disorder	Likely benign; Benign	rs936800749, rs1187822011, rs573129548, rs76552953, rs1417425135	RCV003896650 RCV003931890 RCV003971874 RCV003907354 RCV003946934
Cervical cancer	Benign	rs143549153	RCV005904633
Colon adenocarcinoma	Benign	rs143549153	RCV005904632
Lung cancer	Benign	rs143549153	RCV005904634

Associations from Text Mining
Disease Name	Relationship Type	References
Carcinoma Non Small Cell Lung	Inhibit	34783629
Classical Lissencephalies and Subcortical Band Heterotopias	Associate	8262969
Colorectal Neoplasms	Associate	24966994
Neoplasms	Associate	16948864
Neoplasms	Inhibit	34783629
Neurologic Manifestations	Associate	8262969
Pulmonary Disease Chronic Obstructive	Associate	37650285
Sarcoma	Associate	16948864
Thyroid Cancer Papillary	Associate	37324256
Thyroid Neoplasms	Associate	37854594