Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	28978
Gene name Gene Name - the full gene name approved by the HGNC.	Transmembrane protein 14A
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	TMEM14A
Synonyms (NCBI Gene) Gene synonyms aliases	C6orf73, PTD011
Chromosome Chromosome number	6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	6p12.2

Show/Hide all(138)

miRTarBase ID	miRNA	Experiments	Reference
MIRT002540	hsa-miR-373-3p	Microarray	15685193
MIRT019430	hsa-miR-148b-3p	Microarray	17612493
MIRT002540	hsa-miR-373-3p	Microarray;Other	15685193
MIRT025139	hsa-miR-181a-5p	Microarray	17612493
MIRT025971	hsa-miR-148a-3p	Sequencing	20371350
MIRT439437	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT439437	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT1431369	hsa-miR-181a	CLIP-seq
MIRT1431370	hsa-miR-181b	CLIP-seq
MIRT1431371	hsa-miR-181c	CLIP-seq
MIRT1431372	hsa-miR-181d	CLIP-seq
MIRT1431373	hsa-miR-200b	CLIP-seq
MIRT1431374	hsa-miR-200c	CLIP-seq
MIRT1431375	hsa-miR-3647-3p	CLIP-seq
MIRT1431376	hsa-miR-4262	CLIP-seq
MIRT1431377	hsa-miR-429	CLIP-seq
MIRT1431378	hsa-miR-4427	CLIP-seq
MIRT1431379	hsa-miR-4724-5p	CLIP-seq
MIRT1431380	hsa-miR-664	CLIP-seq
MIRT2129295	hsa-miR-4282	CLIP-seq
MIRT2129296	hsa-miR-570	CLIP-seq
MIRT2350846	hsa-miR-3672	CLIP-seq
MIRT2644438	hsa-miR-1179	CLIP-seq
MIRT2644439	hsa-miR-1206	CLIP-seq
MIRT2644440	hsa-miR-1279	CLIP-seq
MIRT2644441	hsa-miR-129-5p	CLIP-seq
MIRT2644442	hsa-miR-1305	CLIP-seq
MIRT2644443	hsa-miR-208a	CLIP-seq
MIRT2644444	hsa-miR-208b	CLIP-seq
MIRT2644445	hsa-miR-3121-3p	CLIP-seq
MIRT2644446	hsa-miR-3129-3p	CLIP-seq
MIRT2644447	hsa-miR-3148	CLIP-seq
MIRT2644448	hsa-miR-3163	CLIP-seq
MIRT2644449	hsa-miR-3194-3p	CLIP-seq
MIRT2644450	hsa-miR-323-3p	CLIP-seq
MIRT2644451	hsa-miR-3613-3p	CLIP-seq
MIRT2644452	hsa-miR-3616-5p	CLIP-seq
MIRT2644453	hsa-miR-3647-5p	CLIP-seq
MIRT2644454	hsa-miR-3662	CLIP-seq
MIRT2644455	hsa-miR-3671	CLIP-seq
MIRT2350846	hsa-miR-3672	CLIP-seq
MIRT2644456	hsa-miR-3673	CLIP-seq
MIRT2644457	hsa-miR-3688-3p	CLIP-seq
MIRT2644458	hsa-miR-371-5p	CLIP-seq
MIRT2644459	hsa-miR-382	CLIP-seq
MIRT2644460	hsa-miR-3942-5p	CLIP-seq
MIRT2644461	hsa-miR-409-3p	CLIP-seq
MIRT2644462	hsa-miR-410	CLIP-seq
MIRT2644463	hsa-miR-4263	CLIP-seq
MIRT2129295	hsa-miR-4282	CLIP-seq
MIRT2644464	hsa-miR-4422	CLIP-seq
MIRT2644465	hsa-miR-4432	CLIP-seq
MIRT2644466	hsa-miR-4436b-5p	CLIP-seq
MIRT2644467	hsa-miR-4503	CLIP-seq
MIRT2644468	hsa-miR-4645-3p	CLIP-seq
MIRT2644469	hsa-miR-4666-3p	CLIP-seq
MIRT2644470	hsa-miR-4670-3p	CLIP-seq
MIRT2644471	hsa-miR-4677-3p	CLIP-seq
MIRT2644472	hsa-miR-4679	CLIP-seq
MIRT2644473	hsa-miR-4680-5p	CLIP-seq
MIRT2644474	hsa-miR-4694-3p	CLIP-seq
MIRT2644475	hsa-miR-4703-3p	CLIP-seq
MIRT2644476	hsa-miR-4703-5p	CLIP-seq
MIRT2644477	hsa-miR-4777-3p	CLIP-seq
MIRT2644478	hsa-miR-4778-5p	CLIP-seq
MIRT2644479	hsa-miR-496	CLIP-seq
MIRT2644480	hsa-miR-499-5p	CLIP-seq
MIRT2644481	hsa-miR-542-3p	CLIP-seq
MIRT2644482	hsa-miR-548ae	CLIP-seq
MIRT2644483	hsa-miR-548aj	CLIP-seq
MIRT2644484	hsa-miR-548am	CLIP-seq
MIRT2644485	hsa-miR-548x	CLIP-seq
MIRT2129296	hsa-miR-570	CLIP-seq
MIRT2644486	hsa-miR-573	CLIP-seq
MIRT2644487	hsa-miR-576-5p	CLIP-seq
MIRT2644488	hsa-miR-587	CLIP-seq
MIRT2644489	hsa-miR-599	CLIP-seq
MIRT2644490	hsa-miR-607	CLIP-seq
MIRT2644491	hsa-miR-617	CLIP-seq
MIRT2644492	hsa-miR-877	CLIP-seq
MIRT2644493	hsa-miR-885-3p	CLIP-seq
MIRT2644438	hsa-miR-1179	CLIP-seq
MIRT2644439	hsa-miR-1206	CLIP-seq
MIRT2644440	hsa-miR-1279	CLIP-seq
MIRT2644441	hsa-miR-129-5p	CLIP-seq
MIRT2644442	hsa-miR-1305	CLIP-seq
MIRT2644443	hsa-miR-208a	CLIP-seq
MIRT2644444	hsa-miR-208b	CLIP-seq
MIRT2644445	hsa-miR-3121-3p	CLIP-seq
MIRT2644446	hsa-miR-3129-3p	CLIP-seq
MIRT2644447	hsa-miR-3148	CLIP-seq
MIRT2644448	hsa-miR-3163	CLIP-seq
MIRT2644450	hsa-miR-323-3p	CLIP-seq
MIRT2644451	hsa-miR-3613-3p	CLIP-seq
MIRT2644452	hsa-miR-3616-5p	CLIP-seq
MIRT2644453	hsa-miR-3647-5p	CLIP-seq
MIRT2644454	hsa-miR-3662	CLIP-seq
MIRT2350846	hsa-miR-3672	CLIP-seq
MIRT2644456	hsa-miR-3673	CLIP-seq
MIRT2644457	hsa-miR-3688-3p	CLIP-seq
MIRT2644458	hsa-miR-371-5p	CLIP-seq
MIRT2644459	hsa-miR-382	CLIP-seq
MIRT2644460	hsa-miR-3942-5p	CLIP-seq
MIRT2644461	hsa-miR-409-3p	CLIP-seq
MIRT2644462	hsa-miR-410	CLIP-seq
MIRT2129295	hsa-miR-4282	CLIP-seq
MIRT2644464	hsa-miR-4422	CLIP-seq
MIRT2644465	hsa-miR-4432	CLIP-seq
MIRT2644466	hsa-miR-4436b-5p	CLIP-seq
MIRT2693410	hsa-miR-4501	CLIP-seq
MIRT2644467	hsa-miR-4503	CLIP-seq
MIRT2693411	hsa-miR-4504	CLIP-seq
MIRT2644468	hsa-miR-4645-3p	CLIP-seq
MIRT2644469	hsa-miR-4666-3p	CLIP-seq
MIRT2644470	hsa-miR-4670-3p	CLIP-seq
MIRT2644471	hsa-miR-4677-3p	CLIP-seq
MIRT2644472	hsa-miR-4679	CLIP-seq
MIRT2644473	hsa-miR-4680-5p	CLIP-seq
MIRT2644474	hsa-miR-4694-3p	CLIP-seq
MIRT2644475	hsa-miR-4703-3p	CLIP-seq
MIRT2644476	hsa-miR-4703-5p	CLIP-seq
MIRT2644477	hsa-miR-4777-3p	CLIP-seq
MIRT2644478	hsa-miR-4778-5p	CLIP-seq
MIRT2644479	hsa-miR-496	CLIP-seq
MIRT2644480	hsa-miR-499-5p	CLIP-seq
MIRT2644481	hsa-miR-542-3p	CLIP-seq
MIRT2644482	hsa-miR-548ae	CLIP-seq
MIRT2644483	hsa-miR-548aj	CLIP-seq
MIRT2644484	hsa-miR-548am	CLIP-seq
MIRT2644485	hsa-miR-548x	CLIP-seq
MIRT2129296	hsa-miR-570	CLIP-seq
MIRT2644486	hsa-miR-573	CLIP-seq
MIRT2644488	hsa-miR-587	CLIP-seq
MIRT2644489	hsa-miR-599	CLIP-seq
MIRT2644490	hsa-miR-607	CLIP-seq
MIRT2644491	hsa-miR-617	CLIP-seq
MIRT2644492	hsa-miR-877	CLIP-seq
MIRT2644493	hsa-miR-885-3p	CLIP-seq

Show/Hide all(11)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 32296183
GO:0005789	Component	Endoplasmic reticulum membrane	IBA	21873635
GO:0005789	Component	Endoplasmic reticulum membrane	IDA	21723035
GO:0006839	Process	Mitochondrial transport	IBA	21873635
GO:0006915	Process	Apoptotic process	IEA
GO:0016021	Component	Integral component of membrane	IEA
GO:0031966	Component	Mitochondrial membrane	IBA	21873635
GO:0031966	Component	Mitochondrial membrane	IDA	21723035
GO:0043066	Process	Negative regulation of apoptotic process	IMP	21723035
GO:1901029	Process	Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	IBA	21873635
GO:1901029	Process	Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	IMP	21723035

MIM	HGNC	e!Ensembl
616870	21076	ENSG00000096092

Protein

UniProt ID

Q9Y6G1

Protein name

Transmembrane protein 14A

Protein function

Inhibits apoptosis via negative regulation of the mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.

PDB

2LOO , 2LOP

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF03647	Tmemb_14	3 → 94	Transmembrane proteins 14C	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed at significantly higher levels in ovarian cancer tissues than in normal tissues (at protein level). {ECO:0000269|PubMed:26896463}.

Sequence

MDLIGFGYAALVTFGSIFGYKRRGGVPSLIAGLFVGCLAGYGAYRVSNDKRDVKVSLFTA
FFLATIMGVRFKRSKKIMPAGLVAGLSLMMILRLVLLLL

Sequence length

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Leukemia	Leukemia, Myelocytic, Acute	rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297	27903959

Show/Hide Text Mining Associations (9)

Disease Name	Relationship Type	References
Associations from Text Mining
Adenocarcinoma of Lung	Associate	37839105
Breast Neoplasms	Associate	25148458
Carcinogenesis	Associate	26896463
Carcinoma Non Small Cell Lung	Associate	37839105
Fractures Bone	Associate	25148458
Neoplasm Metastasis	Associate	26896463
Neoplasms	Stimulate	37839105
Osteoporosis	Associate	25148458
Ovarian Neoplasms	Associate	26896463

TMEM14A (transmembrane protein 14A)