SLC27A6 (solute carrier family 27 member 6)

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID 28965
Gene name Solute carrier family 27 member 6
Gene symbol SLC27A6
Synonyms (NCBI Gene)
ACSVL2FACVL2FATP6VLCS-H1
Chromosome 5
Chromosome location 5q23.3
Summary This gene encodes a member of the fatty acid transport protein family (FATP). FATPs are involved in the uptake of long-chain fatty acids and have unique expression patterns. Alternatively spliced transcript variants encoding the same protein have been fou
miRNA miRNA information provided by mirtarbase database.
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Gene miRNA Gene ontology Other IDs Protein Pathways
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miRTarBase ID miRNA Experiments Reference
MIRT017231 hsa-miR-335-5p Microarray 18185580
MIRT029105 hsa-miR-26b-5p Microarray 19088304
MIRT1358077 hsa-miR-4282 CLIP-seq
MIRT1358078 hsa-miR-4477a CLIP-seq
MIRT1358079 hsa-miR-4477b CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Gene miRNA Gene ontology Other IDs Protein Pathways
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GO ID Ontology Definition Evidence Reference
GO:0000038 Process Very long-chain fatty acid metabolic process TAS 10471116
GO:0000166 Function Nucleotide binding IEA
GO:0001676 Process Long-chain fatty acid metabolic process IBA
GO:0004467 Function Long-chain fatty acid-CoA ligase activity IBA
GO:0004467 Function Long-chain fatty acid-CoA ligase activity IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein Pathways
MIM HGNC e!Ensembl
604196 11000 ENSG00000113396
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein Pathways
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9Y2P4
Protein name Long-chain fatty acid transport protein 6 (FATP-6) (Fatty acid transport protein 6) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Fatty-acid-coenzyme A ligase, very long-chain 2) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 membe
Protein function Mediates the import of long-chain fatty acids (LCFA) into the cell by facilitating their transport at the plasma membrane (PubMed:12556534). Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00501 AMP-binding 60 → 487 AMP-binding enzyme Family
PF13193 AMP-binding_C 495 → 571 AMP-binding enzyme C-terminal domain Domain
Tissue specificity TISSUE SPECIFICITY: Strongly expressed in heart and localizes to cardiac myocytes (PubMed:12556534). Expressed at moderate levels in placenta, testis, and adrenal glands. Expressed at very low levels in kidney, bladder and uterus. {ECO:0000269|PubMed:1255
Sequence
Sequence length 619
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Gene ontology Other IDs Protein Pathways
  KEGG  Reactome
  PPAR signaling pathway
Insulin resistance 		  Transport of fatty acids