Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
2894
Gene name Gene Name - the full gene name approved by the HGNC.
Glutamate ionotropic receptor delta type subunit 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
GRID1
Synonyms (NCBI Gene) Gene synonyms aliases
GluD1, GluD1-b
Chromosome Chromosome number
10
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
10q23.1-q23.2
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a subunit of glutamate receptor channels. These channels mediate most of the fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity.[provided by RefSeq, Jan 2009]
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT710765 hsa-miR-6758-5p HITS-CLIP 19536157
MIRT710763 hsa-miR-6856-5p HITS-CLIP 19536157
MIRT710764 hsa-miR-6085 HITS-CLIP 19536157
MIRT710762 hsa-miR-6813-5p HITS-CLIP 19536157
MIRT710761 hsa-miR-3126-3p HITS-CLIP 19536157
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0004970 Function Ionotropic glutamate receptor activity IEA
GO:0005886 Component Plasma membrane IBA 21873635
GO:0008066 Function Glutamate receptor activity IBA 21873635
GO:0015276 Function Ligand-gated ion channel activity IBA 21873635
GO:0034220 Process Ion transmembrane transport IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
610659 4575 ENSG00000182771
Protein
UniProt ID Q9ULK0
Protein name Glutamate receptor ionotropic, delta-1 (GluD1) (GluR delta-1 subunit)
Protein function Member of the ionotropic glutamate receptor family, which plays a crucial role in synaptic organization and signal transduction in the central nervous system. Although it shares structural features with ionotropic glutamate receptors, does not b
PDB 8BLJ , 8BN2 , 8BN5
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01094 ANF_receptor 36 403 Receptor family ligand binding region Family
PF10613 Lig_chan-Glu_bd 437 549 Ligated ion channel L-glutamate- and glycine-binding site Domain
PF00060 Lig_chan 562 842 Ligand-gated ion channel Family
Sequence
MEALTLWLLPWICQCVSVRADSIIHIGAIFEENAAKDDRVFQLAVSDLSLNDDILQSEKI
TYSIKVIEANNPFQAVQEACDLMTQGILALVTSTGCASANALQSLTDAMHIPHLFVQRNP
GGSPRTACHLNPSPDGEAYTLASRPPVRLNDVMLRLVTELRWQKFVMFYDSEYDIRGLQS
FLDQASRLGLDVSLQKVDKNISHVFTSLFTTMKTEELNRYRDTLRRAILLLSPQGAHSFI
NEAVETNLASKDSHWVFVNEEISDPEILDLVHSALGRMTVVRQIFPSAKDNQKCTRNNHR
ISSLLCDPQEGYLQMLQISNLYLYDSVLMLANAFHRKLEDRKWHSMASLNCIRKSTKPWN
GGRSMLDTIKKGHITGLTGVMEFREDSSNPYVQFEILGTTYSE
TFGKDMRKLATWDSEKG
LNGSLQERPMGSRLQGLTLKVVTVLEEPFVMVAENILGQPKRYKGFSIDVLDALAKALGF
KYEIYQAPDGRYGHQLHNTSWNGMIGELISKRADLAISAITITPERESVVDFSKRYMDYS
VGILIKKPE
EKISIFSLFAPFDFAVWACIAAAIPVVGVLIFVLNRIQAVRAQSAAQPRPS
ASATLHSAIWIVYGAFVQQGGESSVNSMAMRIVMGSWWLFTLIVCSSYTANLAAFLTVSR
MDNPIRTFQDLSKQVEMSYGTVRDSAVYEYFRAKGTNPLEQDSTFAELWRTISKNGGADN
CVSSPSEGIRKAKKGNYAFLWDVAVVEYAALTDDDCSVTVIGNSISSKGYGIALQHGSPY
RDLFSQRILELQDTGDLDVLKQKWWPHMGRCDLTSHASAQADGKSLKLHSFAGVFCILAI
GL
LLACLVAALELWWNSNRCHQETPKEDKEVNLEQVHRRMNSLMDEDIAHKQISPASIEL
SALEMGGLAPTQTLEPTREYQNTQLSVSTFLPEQSSHGTSRTLSSGPSSNLPLPLSSSAT
MPSMQCKHRSPNGGLFRQSPVKTPIPMSFQPVPGGVLPEALDTSHGTSI
Sequence length 1009
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  Neuroactive ligand-receptor interaction  
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Breast cancer Malignant neoplasm of breast rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158
View all (309 more)
20852631
Colorectal cancer Colorectal Carcinoma rs137854568, rs137854573, rs137854575, rs387906234, rs121908380, rs121908702, rs267606674, rs794729661, rs121909055, rs281865417, rs267606884, rs28934575, rs587776769, rs104893815, rs587776800
View all (467 more)
21278247
Colorectal neoplasms Colorectal Neoplasms rs28929483, rs63751108, rs28929484, rs63749831, rs63750047, rs63751207, rs63749811, rs1553350126, rs63750875, rs63750955, rs587776706, rs63750871, rs587776715, rs63751466, rs63750049
View all (1682 more)
21278247
Leukemia Leukemia, Myelocytic, Acute rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297 27903959
Unknown
Disease term Disease name Evidence References Source
Asthma Asthma 27611488 ClinVar, GWAS
Mental depression Mental Depression, Depressive disorder 22064162, 22412961, 23560106 ClinVar
Hyperopia Hyperopia GWAS
Anorexia Anorexia GWAS
Associations from Text Mining
Disease Name Relationship Type References
Adenocarcinoma of Lung Associate 35029906
Affective Disorders Psychotic Associate 38012695
Alcoholism Associate 22064162
Alzheimer Disease Associate 32193444
Autism Spectrum Disorder Associate 22543975
Bipolar Disorder Associate 29248581, 38012695
Depressive Disorder Associate 22064162, 38012695
Mental Disorders Associate 29248581
Psychotic Disorders Associate 16380905
Rett Syndrome Associate 24916645