Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
2894
Gene name Gene Name - the full gene name approved by the HGNC.
Glutamate ionotropic receptor delta type subunit 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
GRID1
Synonyms (NCBI Gene) Gene synonyms aliases
GluD1, GluD1-b
Chromosome Chromosome number
10
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
10q23.1-q23.2
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a subunit of glutamate receptor channels. These channels mediate most of the fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity.[provided by RefSeq, Jan 2009]
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT710765 hsa-miR-6758-5p HITS-CLIP 19536157
MIRT710763 hsa-miR-6856-5p HITS-CLIP 19536157
MIRT710764 hsa-miR-6085 HITS-CLIP 19536157
MIRT710762 hsa-miR-6813-5p HITS-CLIP 19536157
MIRT710761 hsa-miR-3126-3p HITS-CLIP 19536157
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0004971 Function AMPA glutamate receptor activity IBA
GO:0005216 Function Monoatomic ion channel activity IEA
GO:0005515 Function Protein binding IPI 28514442, 33961781
GO:0005886 Component Plasma membrane IBA
GO:0005886 Component Plasma membrane IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
610659 4575 ENSG00000182771
Protein
UniProt ID Q9ULK0
Protein name Glutamate receptor ionotropic, delta-1 (GluD1) (GluR delta-1 subunit)
Protein function Member of the ionotropic glutamate receptor family, which plays a crucial role in synaptic organization and signal transduction in the central nervous system. Although it shares structural features with ionotropic glutamate receptors, does not b
PDB 8BLJ , 8BN2 , 8BN5
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01094 ANF_receptor 36 403 Receptor family ligand binding region Family
PF10613 Lig_chan-Glu_bd 437 549 Ligated ion channel L-glutamate- and glycine-binding site Domain
PF00060 Lig_chan 562 842 Ligand-gated ion channel Family
Sequence
MEALTLWLLPWICQCVSVRADSIIHIGAIFEENAAKDDRVFQLAVSDLSLNDDILQSEKI
TYSIKVIEANNPFQAVQEACDLMTQGILALVTSTGCASANALQSLTDAMHIPHLFVQRNP
GGSPRTACHLNPSPDGEAYTLASRPPVRLNDVMLRLVTELRWQKFVMFYDSEYDIRGLQS
FLDQASRLGLDVSLQKVDKNISHVFTSLFTTMKTEELNRYRDTLRRAILLLSPQGAHSFI
NEAVETNLASKDSHWVFVNEEISDPEILDLVHSALGRMTVVRQIFPSAKDNQKCTRNNHR
ISSLLCDPQEGYLQMLQISNLYLYDSVLMLANAFHRKLEDRKWHSMASLNCIRKSTKPWN
GGRSMLDTIKKGHITGLTGVMEFREDSSNPYVQFEILGTTYSE
TFGKDMRKLATWDSEKG
LNGSLQERPMGSRLQGLTLKVVTVLEEPFVMVAENILGQPKRYKGFSIDVLDALAKALGF
KYEIYQAPDGRYGHQLHNTSWNGMIGELISKRADLAISAITITPERESVVDFSKRYMDYS
VGILIKKPE
EKISIFSLFAPFDFAVWACIAAAIPVVGVLIFVLNRIQAVRAQSAAQPRPS
ASATLHSAIWIVYGAFVQQGGESSVNSMAMRIVMGSWWLFTLIVCSSYTANLAAFLTVSR
MDNPIRTFQDLSKQVEMSYGTVRDSAVYEYFRAKGTNPLEQDSTFAELWRTISKNGGADN
CVSSPSEGIRKAKKGNYAFLWDVAVVEYAALTDDDCSVTVIGNSISSKGYGIALQHGSPY
RDLFSQRILELQDTGDLDVLKQKWWPHMGRCDLTSHASAQADGKSLKLHSFAGVFCILAI
GL
LLACLVAALELWWNSNRCHQETPKEDKEVNLEQVHRRMNSLMDEDIAHKQISPASIEL
SALEMGGLAPTQTLEPTREYQNTQLSVSTFLPEQSSHGTSRTLSSGPSSNLPLPLSSSAT
MPSMQCKHRSPNGGLFRQSPVKTPIPMSFQPVPGGVLPEALDTSHGTSI
Sequence length 1009
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  Neuroactive ligand-receptor interaction  
<
Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Anorexia Anorexia nervosa N/A N/A GWAS
Asthma Asthma (childhood onset), Asthma N/A N/A GWAS
Barrett esophagus Barrett's esophagus N/A N/A GWAS
Diabetes Type 2 diabetes N/A N/A GWAS
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Adenocarcinoma of Lung Associate 35029906
Affective Disorders Psychotic Associate 38012695
Alcoholism Associate 22064162
Alzheimer Disease Associate 32193444
Autism Spectrum Disorder Associate 22543975
Bipolar Disorder Associate 29248581, 38012695
Depressive Disorder Associate 22064162, 38012695
Mental Disorders Associate 29248581
Psychotic Disorders Associate 16380905
Rett Syndrome Associate 24916645