IGLV10-54 (immunoglobulin lambda variable 10-54)

Gene
Gene Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
28772
Gene name Gene Name - the full gene name approved by the HGNC.
Immunoglobulin lambda variable 10-54
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
IGLV10-54
Synonyms (NCBI Gene) Gene synonyms aliases
IGLV1054, V1-20
Chromosome Chromosome number
22
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
22q11.22
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Protein Associated diseases
Show/Hide all(6)
GO ID Ontology Definition Evidence Reference
GO:0002250 Process Adaptive immune response IEA
GO:0002377 Process Immunoglobulin production IBA 21873635
GO:0005615 Component Extracellular space IBA 21873635
GO:0005886 Component Plasma membrane IEA
GO:0006955 Process Immune response IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
HGNC N/A IGLV10-54
Protein
Gene Gene ontology Other IDs Protein Associated diseases
UniProt ID A0A075B6I4
Protein name Immunoglobulin lambda variable 10-54
Protein function V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07686 V-set 24 → 116 Immunoglobulin V-set domain Domain
Sequence
Sequence length 117
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene Gene ontology Other IDs Protein Associated diseases
Show/Hide Causal Diseases (2)
Causal
Disease term Disease name dbSNP ID References
Anemia Anemia rs118204044, rs118204045, rs118204046, rs121918330, rs869320719, rs869312029, rs121918332, rs869320724, rs767094129, rs786205058, rs786205059, rs137853119, rs137853120, rs137853121, rs1384933966
View all (89 more)		 21483845
Leukemia Leukemia, Myelocytic, Acute rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297 27903959
Show/Hide Unknown Diseases (1)
Unknown
Disease term Disease name Evidence References Source
Mental depression Major Depressive Disorder 27622933 ClinVar