Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
286046
Gene name Gene Name - the full gene name approved by the HGNC.
XK related 6
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
XKR6
Synonyms (NCBI Gene) Gene synonyms aliases
C8orf21, C8orf5, C8orf7, XRG6
Chromosome Chromosome number
8
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
8p23.1
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT017113 hsa-miR-335-5p Microarray 18185580
MIRT707490 hsa-miR-6074 HITS-CLIP 21572407
MIRT707489 hsa-miR-3924 HITS-CLIP 21572407
MIRT518127 hsa-miR-5011-5p HITS-CLIP 21572407
MIRT518126 hsa-miR-190a-3p HITS-CLIP 21572407
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005886 Component Plasma membrane IBA
GO:0005886 Component Plasma membrane IEA
GO:0005886 Component Plasma membrane IEA
GO:0005886 Component Plasma membrane ISS
GO:0016020 Component Membrane IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein
UniProt ID Q5GH73
Protein name XK-related protein 6
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF09815 XK-related 130 501 XK-related protein Family
Sequence
MAAKSDGGGVGVGFAQLHNLDEAVGSGGEEDGEPGGGGCGGGGDGSEPGESSSMHICHCC
NTSSCYWGCRSACLRSLLGRKPRRSAAADGGDQPLQPPAAPGAGRQPPTPSAARPEPPPP
QVERPWLDCLWIVLALLVFFGDVGTDLWLALDYYRKGDYVYFGLTLFFVLVPSLLVQSLS
FRWFVQDYTGGGLGAVEGLTSRGPPMMGAGYVHGAARGGPGVRVSPTPGAQRLCRLSVWI
WQSVIHLLQMGQVWRYIRTMYLGIQSQRRKEHQRRFYWAMMYEYADVNMLRLLETFLESA
PQLVLQLYIMLQKNSAETLPCVSSVTSLMSLAWVLASYHKLLRDSRDDKKSMSYRGAIIQ
VFWRLFTISSRVISFALFASIFQLYFGIFVVVHWCAMAFWIIHGGTDFCMSKWEEILFNM
VVGIVYIFCWFNVKEGRTRYRMFAYYTIVLTENAALTFLWYFYRDPETTDSYAVPALCCV
FISFVAGIAMMLLYYGVLHPT
GPRAKILASSCCAELLWGIPLPPDVEPMAPEIPGYRGTQ
VTPTRAVTEQQEDLTADTCLPVFQVRPMGPPTPLGRPYLPEGPLIKIDMPRKRYPAWDAH
FVDRRLRRTINILQYVTPTAVGIRYRDGPLLYELLQYESSL
Sequence length 641
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  Efferocytosis  
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Anxiety Disorder Anxiety N/A N/A GWAS
Diabetes Type 2 diabetes N/A N/A GWAS
Eosinophilia Eosinophilic esophagitis N/A N/A GWAS
Hypertension Hypertension N/A N/A GWAS
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Cerebral Infarction Associate 31429711, 32024373
Coronary Artery Disease Associate 31429711
Coronary Disease Associate 32024373
Dementia Vascular Associate 39909351
Hypertension Associate 32024373
Idiopathic Pulmonary Fibrosis Associate 37266442
Lupus Erythematosus Systemic Associate 23049788, 28289186, 29967481
Lupus Nephritis Associate 23049788
Melanoma Associate 32241263
Sjogren's Syndrome Associate 35896530