PRR18 (proline rich 18)

Gene

• Entrez ID: 285800
• Gene name: Proline rich 18
• Gene symbol: PRR18
• Synonyms (NCBI Gene): -
• Chromosome: 6
• Chromosome location: 6q27

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT1266909	hsa-miR-1226	CLIP-seq
MIRT1266910	hsa-miR-1237	CLIP-seq
MIRT1266911	hsa-miR-1248	CLIP-seq
MIRT1266912	hsa-miR-1303	CLIP-seq
MIRT1266913	hsa-miR-3135	CLIP-seq
MIRT1266914	hsa-miR-3143	CLIP-seq
MIRT1266915	hsa-miR-3195	CLIP-seq
MIRT1266916	hsa-miR-4284	CLIP-seq
MIRT1266917	hsa-miR-4302	CLIP-seq
MIRT1266918	hsa-miR-4437	CLIP-seq
MIRT1266919	hsa-miR-4685-5p	CLIP-seq
MIRT1266920	hsa-miR-4733-3p	CLIP-seq
MIRT1266921	hsa-miR-4738-5p	CLIP-seq
MIRT1266922	hsa-miR-543	CLIP-seq

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q8N4B5
• Protein name: Proline-rich protein 18
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15671	PRR18	28 → 295	Proline-rich protein family 18	Family

• Sequence:

  MPFPPMPPPPAPAPGAQAARQLPRRPCAAGDKKKRPPQRPEGLLSSSWPSATLKRPPARR
  GPGLDRTQPPAPPGVSPQALPSRARAPATCAPPRPAGSGHSPARTTYAATSAGTGTTAAG
  TSSGAGPCPDSAARFCLNLTPEAVLVIQKRHLEKQLLARPRRPFPSPSAEPRRLLAPCLP
  ARAAGPRRGGPASDPDAPPTAGQGRRAPPPGAQLLHGGLQVPQLSPRPGALRPMLKVSLL
  NERHRYDDVEYEEEPEAVDEGLVRKCTEWLRGVESAAAARGRAGALDSRRHLSTL

• Sequence length: 295

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
BREAST CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLORECTAL CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCOLIOSIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations