Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
285761
Gene name Gene Name - the full gene name approved by the HGNC.
Discoidin, CUB and LCCL domain containing 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
DCBLD1
Synonyms (NCBI Gene) Gene synonyms aliases
dJ94G16.1
Chromosome Chromosome number
6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
6q22.1
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT048575 hsa-miR-100-5p CLASH 23622248
MIRT041861 hsa-miR-484 CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0016021 Component Integral component of membrane IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein
UniProt ID Q8N8Z6
Protein name Discoidin, CUB and LCCL domain-containing protein 1
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00431 CUB 41 147 CUB domain Domain
PF03815 LCCL 156 248 LCCL domain Domain
PF00754 F5_F8_type_C 266 409 F5/8 type C domain Domain
Sequence
MVPGARGGGALARAAGRGLLALLLAVSAPLRLQAEELGDGCGHLVTYQDSGTMTSKNYPG
TYPNHTVCEKTITVPKGKRLILRLGDLDIESQTCASDYLLFTSSSDQYGPYCGSMTVPKE
LLLNTSEVTVRFESGSHISGRGFLLTY
ASSDHPDLITCLERASHYLKTEYSKFCPAGCRD
VAGDISGNMVDGYRDTSLLCKAAIHAGIIADELGGQISVLQRKGISRYEGILANGVLSRD
GSLSDKRF
LFTSNGCSRSLSFEPDGQIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWA
SGDSSNNHKPREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSFVMNFKNNNSKWKTYKG
IVNNEEKVFQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQRIALKVEL
IGCQITQGNDS
LVWRKTSQSTSVSTKKEDETITRPIPSEETSTGINITTVAIPLVLLVVLVFAGMGIFAAF
RKKKKKGSPYGSAEAQKTDCWKQIKYPFARHQSAEFTISYDNEKEMTQKLDLITSDMADY
QQPLMIGTGTVTRKGSTFRPMDTDAEEAGVSTDAGGHYDCPQRAGRHEYALPLAPPEPEY
ATPIVERHVLRAHTFSAQSGYRVPGPQPGHKHSLSSGGFSPVAGVGAQDGDYQRPHSAQP
ADRGYDRPKAVSALATESGHPDSQKPPTHPGTSDSYSAPRDCLTPLNQTAMTALL
Sequence length 715
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Atrial fibrillation Atrial Fibrillation rs120074192, rs121908590, rs121908593, rs121434558, rs587776851, rs387906612, rs387906613, rs387906614, rs387906615, rs199472687, rs199472705, rs199473324, rs587777336, rs587777339, rs587777557
View all (6 more)
29892015
Colonic neoplasms Malignant tumor of colon rs267607789, rs774277300, rs781222233, rs1060502734, rs1060503333, rs1339238483 26151821
Colorectal cancer Colorectal Carcinoma, Adenocarcinoma of large intestine rs137854568, rs137854573, rs137854575, rs387906234, rs121908380, rs121908702, rs267606674, rs794729661, rs121909055, rs281865417, rs267606884, rs28934575, rs587776769, rs104893815, rs587776800
View all (467 more)
26151821
Colorectal neoplasms Colorectal Neoplasms, Malignant neoplasm of large intestine rs28929483, rs63751108, rs28929484, rs63749831, rs63750047, rs63751207, rs63749811, rs1553350126, rs63750875, rs63750955, rs587776706, rs63750871, rs587776715, rs63751466, rs63750049
View all (1682 more)
26151821
Unknown
Disease term Disease name Evidence References Source
Colorectal Cancer Colorectal Cancer In summary, our data strongly demonstrated that upregulation of GRB7 conferred MEKi resistance in CRC cells with KRAS mutations by mediating RTK signaling through the recruitment of PLK1. GWAS, CBGDA
Atrial Fibrillation Atrial Fibrillation GWAS
Bipolar Disorder Bipolar Disorder GWAS
Diabetes Diabetes GWAS
Associations from Text Mining
Disease Name Relationship Type References
Adenocarcinoma of Lung Associate 28025329
Adenocarcinoma of Lung Stimulate 30212242
Breast Neoplasms Associate 34140574
Carcinogenesis Associate 36308382
Carcinoma Non Small Cell Lung Associate 34140574
Carcinoma Squamous Cell Associate 37746966
Colorectal Neoplasms Associate 26383524, 35512400
Lung Neoplasms Associate 26689248, 36308382
Neoplasm Metastasis Associate 38291438
Neoplasms Associate 35844572, 38291438