Gene Gene information from NCBI Gene database.
Entrez ID 285672
Gene name SREK1 interacting protein 1
Gene symbol SREK1IP1
Synonyms (NCBI Gene)
P18SRPSFRS12IP1
Chromosome 5
Chromosome location 5q12.3
miRNA miRNA information provided by mirtarbase database.
813
miRTarBase ID miRNA Experiments Reference
MIRT016115 hsa-miR-421 Sequencing 20371350
MIRT027283 hsa-miR-101-3p Sequencing 20371350
MIRT029124 hsa-miR-26b-5p Microarray 19088304
MIRT032136 hsa-let-7d-5p Sequencing 20371350
MIRT049843 hsa-miR-92a-3p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
6
GO ID Ontology Definition Evidence Reference
GO:0003676 Function Nucleic acid binding IEA
GO:0005515 Function Protein binding IPI 25416956, 31515488, 32296183
GO:0006397 Process MRNA processing IEA
GO:0008270 Function Zinc ion binding IEA
GO:0008380 Process RNA splicing IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8N9Q2
Protein name Protein SREK1IP1 (SFRS12-interacting protein 1) (SREK1-interacting protein 1) (Splicing regulatory protein of 18 kDa) (p18SRP)
Protein function Possible splicing regulator involved in the control of cellular survival.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13917 zf-CCHC_3 9 50 Domain
Sequence
MAVPGCNKDSVRAGCKKCGYPGHLTFECRNFLRVDPKRDIVLDVSSTSSEDSDEENEELN
KLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKE
KKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK
Sequence length 155
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
5
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ATTENTION DEFICIT HYPERACTIVITY DISORDER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
AUTISM SPECTRUM DISORDER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
CENTRAL NERVOUS SYSTEM CANCER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
GLIOBLASTOMA MULTIFORME GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Colorectal Neoplasms Associate 21209843
★☆☆☆☆
Found in Text Mining only
Congenital anosmia Associate 38148624
★☆☆☆☆
Found in Text Mining only