FAM153A (family with sequence similarity 153 member A)

Gene

• Entrez ID: 285596
• Gene name: Family with sequence similarity 153 member A
• Gene symbol: FAM153A
• Synonyms (NCBI Gene): NY-REN-7
• Chromosome: 5
• Chromosome location: 5q35.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT980853	hsa-miR-1915	CLIP-seq
MIRT980854	hsa-miR-4459	CLIP-seq
MIRT980855	hsa-miR-4695-5p	CLIP-seq
MIRT980856	hsa-miR-4726-3p	CLIP-seq
MIRT980857	hsa-miR-665	CLIP-seq
MIRT2224795	hsa-miR-128	CLIP-seq
MIRT2224796	hsa-miR-130a	CLIP-seq
MIRT2224797	hsa-miR-130b	CLIP-seq
MIRT2224798	hsa-miR-148a	CLIP-seq
MIRT2224799	hsa-miR-148b	CLIP-seq
MIRT2224800	hsa-miR-152	CLIP-seq
MIRT2224801	hsa-miR-19a	CLIP-seq
MIRT2224802	hsa-miR-19b	CLIP-seq
MIRT2224803	hsa-miR-301a	CLIP-seq
MIRT2224804	hsa-miR-301b	CLIP-seq
MIRT2224805	hsa-miR-3666	CLIP-seq
MIRT2224806	hsa-miR-4295	CLIP-seq
MIRT2224807	hsa-miR-432	CLIP-seq
MIRT2224808	hsa-miR-454	CLIP-seq
MIRT2224809	hsa-miR-498	CLIP-seq
MIRT2224810	hsa-miR-518a-5p	CLIP-seq
MIRT2224811	hsa-miR-527	CLIP-seq
MIRT2224795	hsa-miR-128	CLIP-seq
MIRT2449153	hsa-miR-129-3p	CLIP-seq
MIRT2224796	hsa-miR-130a	CLIP-seq
MIRT2224797	hsa-miR-130b	CLIP-seq
MIRT2224798	hsa-miR-148a	CLIP-seq
MIRT2224799	hsa-miR-148b	CLIP-seq
MIRT2224800	hsa-miR-152	CLIP-seq
MIRT2224801	hsa-miR-19a	CLIP-seq
MIRT2224802	hsa-miR-19b	CLIP-seq
MIRT2224803	hsa-miR-301a	CLIP-seq
MIRT2224804	hsa-miR-301b	CLIP-seq
MIRT2224805	hsa-miR-3666	CLIP-seq
MIRT2224806	hsa-miR-4295	CLIP-seq
MIRT2224807	hsa-miR-432	CLIP-seq
MIRT2224808	hsa-miR-454	CLIP-seq
MIRT2224810	hsa-miR-518a-5p	CLIP-seq
MIRT2224811	hsa-miR-527	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q9UHL3
• Protein name: Protein FAM153A (Renal carcinoma antigen NY-REN-7)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15722	FAM153	1 → 77	FAM153 family	Family
  PF15722	FAM153	87 → 150	FAM153 family	Family
  PF15722	FAM153	145 → 211	FAM153 family	Family
  PF15722	FAM153	210 → 280	FAM153 family	Family

• Sequence:

  MVDKDTERDIEMKRQLRRLRELHLYSTWKKYQEAMKTSLGVPQCERDEGSLGKPLCPPEI
  LSETLPGSVKKRVCFPSEDHLEEFIAEHLPEASNQSLLTVAHADAGTQTNGDLEDLEEHG
  PGQTVSEEATEVHTMEGDPDTLAEFLIRDVLQELSSYNGEEEDPEEVKTSLGVPQRGDLE
  DLEEHVPGQTVSEEATGVHMMQVDPATLAKSDLEDLEEHVPEQTVSEEATGVHMMQVDPA
  TLAKQLEDSTITGSHQQMSASPSSAPAEEATEKTKVEEEVKTRKPKKKTRKPSKKSRWNV
  LKCWDIFNIF

• Sequence length: 310

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
MALIGNANT EPITHELIAL TUMOR OF OVARY	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OVARIAN CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations