Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
284996
Gene name Gene Name - the full gene name approved by the HGNC.
Ring finger protein 149
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
RNF149
Synonyms (NCBI Gene) Gene synonyms aliases
DNAPTP2
Chromosome Chromosome number
2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
2q11.2
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT002520 hsa-miR-373-3p Microarray 15685193
MIRT002520 hsa-miR-373-3p Microarray;Other 15685193
MIRT031790 hsa-miR-16-5p Sequencing 20371350
MIRT046533 hsa-miR-15b-5p CLASH 23622248
MIRT045180 hsa-miR-186-5p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005737 Component Cytoplasm IBA
GO:0005770 Component Late endosome IBA
GO:0005783 Component Endoplasmic reticulum IBA
GO:0005794 Component Golgi apparatus IBA
GO:0006511 Process Ubiquitin-dependent protein catabolic process IBA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein
UniProt ID Q8NC42
Protein name E3 ubiquitin-protein ligase RNF149 (EC 2.3.2.27) (DNA polymerase-transactivated protein 2) (RING finger protein 149) (RING-type E3 ubiquitin transferase RNF149)
Protein function E3 ubiquitin-protein ligase. Ubiquitinates BRAF, inducing its proteasomal degradation.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02225 PA 76 171 PA domain Family
PF13639 zf-RING_2 267 310 Ring finger domain Domain
Sequence
MAWRRREASVGARGVLALALLALALCVPGARGRALEWFSAVVNIEYVDPQTNLTVWSVSE
SGRFGDSSPKEGAHGLVGVPWAPGGDLEGCAPDTRFFVPEPGGRGAAPWVALVARGGCTF
KDKVLVAARRNASAVVLYNEERYGNITLPMSHAGTGNIVVIMISYPKGREI
LELVQKGIP
VTMTIGVGTRHVQEFISGQSVVFVAIAFITMMIISLAWLIFYYIQRFLYTGSQIGSQSHR
KETKKVIGQLLLHTVKHGEKGIDVDAENCAVCIENFKVKDIIRILPCKHIFHRICIDPWL
LDHRTCPMCK
LDVIKALGYWGEPGDVQEMPAPESPPGRDPAANLSLALPDDDGSDDSSPP
SASPAESEPQCDPSFKGDAGENTALLEAGRSDSRHGGPIS
Sequence length 400
Interactions View interactions
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