Gene Gene information from NCBI Gene database.
Entrez ID 284443
Gene name Zinc finger protein 493
Gene symbol ZNF493
Synonyms (NCBI Gene)
-
Chromosome 19
Chromosome location 19p12
miRNA miRNA information provided by mirtarbase database.
785
miRTarBase ID miRNA Experiments Reference
MIRT020784 hsa-miR-155-5p Reporter assay;Other 20584899
MIRT1526578 hsa-miR-1179 CLIP-seq
MIRT1526579 hsa-miR-1185 CLIP-seq
MIRT1526580 hsa-miR-1207-5p CLIP-seq
MIRT1526581 hsa-miR-1224-5p CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
9
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IEA
GO:0001227 Function DNA-binding transcription repressor activity, RNA polymerase II-specific IEA
GO:0003677 Function DNA binding IEA
GO:0005515 Function Protein binding IPI 32296183
GO:0005634 Component Nucleus IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q6ZR52
Protein name Zinc finger protein 493
Protein function May be involved in transcriptional regulation.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00096 zf-C2H2 82 104 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 111 131 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 137 159 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 249 271 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 277 299 Zinc finger, C2H2 type Domain
PF13912 zf-C2H2_6 305 330 Domain
PF00096 zf-C2H2 333 355 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 361 383 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 389 411 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 417 439 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 445 467 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 473 495 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 501 523 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 529 551 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 557 579 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 585 607 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 613 635 Zinc finger, C2H2 type Domain
Sequence
Sequence length 646
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Generic Transcription Pathway
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
STROKE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Bipolar Disorder Associate 30318722
★☆☆☆☆
Found in Text Mining only
Respiratory Distress Syndrome Associate 33818300
★☆☆☆☆
Found in Text Mining only
Sepsis Associate 33818300
★☆☆☆☆
Found in Text Mining only