NKPD1 (NTPase KAP family P-loop domain containing 1)

Gene

• Entrez ID: 284353
• Gene name: NTPase KAP family P-loop domain containing 1
• Gene symbol: NKPD1
• Synonyms (NCBI Gene): -
• Chromosome: 19
• Chromosome location: 19q13.32

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT718649	hsa-miR-759	HITS-CLIP	19536157
MIRT718648	hsa-miR-4514	HITS-CLIP	19536157
MIRT718647	hsa-miR-4692	HITS-CLIP	19536157
MIRT718646	hsa-miR-6515-3p	HITS-CLIP	19536157
MIRT718645	hsa-miR-412-3p	HITS-CLIP	19536157
MIRT718644	hsa-miR-6754-3p	HITS-CLIP	19536157
MIRT718643	hsa-miR-6837-3p	HITS-CLIP	19536157
MIRT718642	hsa-miR-4660	HITS-CLIP	19536157
MIRT718641	hsa-miR-1207-5p	HITS-CLIP	19536157
MIRT718640	hsa-miR-4763-3p	HITS-CLIP	19536157
MIRT718639	hsa-miR-4736	HITS-CLIP	19536157
MIRT718638	hsa-miR-197-3p	HITS-CLIP	19536157
MIRT718637	hsa-miR-7150	HITS-CLIP	19536157
MIRT672601	hsa-miR-5693	HITS-CLIP	23824327
MIRT672600	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT675195	hsa-miR-3194-3p	HITS-CLIP	23824327
MIRT672599	hsa-miR-3135b	HITS-CLIP	23824327
MIRT672598	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT672597	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT672596	hsa-miR-593-5p	HITS-CLIP	23824327
MIRT672595	hsa-miR-3652	HITS-CLIP	23824327
MIRT672594	hsa-miR-4430	HITS-CLIP	23824327
MIRT672593	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT672592	hsa-miR-891a-3p	HITS-CLIP	23824327
MIRT675194	hsa-miR-5691	HITS-CLIP	23824327
MIRT675193	hsa-miR-6805-3p	HITS-CLIP	23824327
MIRT675192	hsa-miR-8057	HITS-CLIP	23824327
MIRT672591	hsa-miR-5698	HITS-CLIP	23824327
MIRT672601	hsa-miR-5693	HITS-CLIP	23824327
MIRT672600	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT672599	hsa-miR-3135b	HITS-CLIP	23824327
MIRT672598	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT672597	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT672596	hsa-miR-593-5p	HITS-CLIP	23824327
MIRT672595	hsa-miR-3652	HITS-CLIP	23824327
MIRT672594	hsa-miR-4430	HITS-CLIP	23824327
MIRT672593	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT672592	hsa-miR-891a-3p	HITS-CLIP	23824327
MIRT672591	hsa-miR-5698	HITS-CLIP	23824327
MIRT718649	hsa-miR-759	HITS-CLIP	19536157
MIRT718648	hsa-miR-4514	HITS-CLIP	19536157
MIRT718647	hsa-miR-4692	HITS-CLIP	19536157
MIRT718646	hsa-miR-6515-3p	HITS-CLIP	19536157
MIRT718645	hsa-miR-412-3p	HITS-CLIP	19536157
MIRT718644	hsa-miR-6754-3p	HITS-CLIP	19536157
MIRT718643	hsa-miR-6837-3p	HITS-CLIP	19536157
MIRT718642	hsa-miR-4660	HITS-CLIP	19536157
MIRT718641	hsa-miR-1207-5p	HITS-CLIP	19536157
MIRT718640	hsa-miR-4763-3p	HITS-CLIP	19536157
MIRT718639	hsa-miR-4736	HITS-CLIP	19536157
MIRT718638	hsa-miR-197-3p	HITS-CLIP	19536157
MIRT718637	hsa-miR-7150	HITS-CLIP	19536157
MIRT672601	hsa-miR-5693	HITS-CLIP	23824327
MIRT672600	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT675195	hsa-miR-3194-3p	HITS-CLIP	23824327
MIRT672599	hsa-miR-3135b	HITS-CLIP	23824327
MIRT672598	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT672597	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT672596	hsa-miR-593-5p	HITS-CLIP	23824327
MIRT672595	hsa-miR-3652	HITS-CLIP	23824327
MIRT672594	hsa-miR-4430	HITS-CLIP	23824327
MIRT672593	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT672592	hsa-miR-891a-3p	HITS-CLIP	23824327
MIRT675194	hsa-miR-5691	HITS-CLIP	23824327
MIRT675193	hsa-miR-6805-3p	HITS-CLIP	23824327
MIRT675192	hsa-miR-8057	HITS-CLIP	23824327
MIRT672591	hsa-miR-5698	HITS-CLIP	23824327
MIRT672601	hsa-miR-5693	HITS-CLIP	23824327
MIRT672600	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT672599	hsa-miR-3135b	HITS-CLIP	23824327
MIRT672598	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT672597	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT672596	hsa-miR-593-5p	HITS-CLIP	23824327
MIRT672595	hsa-miR-3652	HITS-CLIP	23824327
MIRT672594	hsa-miR-4430	HITS-CLIP	23824327
MIRT672593	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT672592	hsa-miR-891a-3p	HITS-CLIP	23824327
MIRT672591	hsa-miR-5698	HITS-CLIP	23824327
MIRT1186401	hsa-miR-122	CLIP-seq
MIRT1186402	hsa-miR-1224-3p	CLIP-seq
MIRT1186403	hsa-miR-1245	CLIP-seq
MIRT1186404	hsa-miR-1260	CLIP-seq
MIRT1186405	hsa-miR-1260b	CLIP-seq
MIRT1186406	hsa-miR-127-5p	CLIP-seq
MIRT1186407	hsa-miR-1280	CLIP-seq
MIRT1186408	hsa-miR-1296	CLIP-seq
MIRT1186409	hsa-miR-1297	CLIP-seq
MIRT1186410	hsa-miR-136	CLIP-seq
MIRT1186411	hsa-miR-137	CLIP-seq
MIRT1186412	hsa-miR-25	CLIP-seq
MIRT1186413	hsa-miR-26a	CLIP-seq
MIRT1186414	hsa-miR-26b	CLIP-seq
MIRT1186415	hsa-miR-2909	CLIP-seq
MIRT1186416	hsa-miR-3158-3p	CLIP-seq
MIRT1186417	hsa-miR-32	CLIP-seq
MIRT1186418	hsa-miR-363	CLIP-seq
MIRT1186419	hsa-miR-367	CLIP-seq
MIRT1186420	hsa-miR-4446-3p	CLIP-seq
MIRT1186421	hsa-miR-4465	CLIP-seq
MIRT1186422	hsa-miR-4532	CLIP-seq
MIRT1186423	hsa-miR-4729	CLIP-seq
MIRT1186424	hsa-miR-532-3p	CLIP-seq
MIRT1186425	hsa-miR-760	CLIP-seq
MIRT1186426	hsa-miR-767-5p	CLIP-seq
MIRT1186427	hsa-miR-92a	CLIP-seq
MIRT1186428	hsa-miR-92b	CLIP-seq
MIRT1551770	hsa-miR-1275	CLIP-seq
MIRT1551771	hsa-miR-4525	CLIP-seq
MIRT1551772	hsa-miR-4665-5p	CLIP-seq
MIRT1551773	hsa-miR-4723-5p	CLIP-seq
MIRT1551774	hsa-miR-625	CLIP-seq
MIRT2053983	hsa-miR-1237	CLIP-seq
MIRT2053984	hsa-miR-1248	CLIP-seq
MIRT1551770	hsa-miR-1275	CLIP-seq
MIRT2053985	hsa-miR-1303	CLIP-seq
MIRT2053986	hsa-miR-197	CLIP-seq
MIRT2053987	hsa-miR-3065-3p	CLIP-seq
MIRT1186416	hsa-miR-3158-3p	CLIP-seq
MIRT2053988	hsa-miR-412	CLIP-seq
MIRT2053989	hsa-miR-4438	CLIP-seq
MIRT2053990	hsa-miR-4447	CLIP-seq
MIRT2053991	hsa-miR-4472	CLIP-seq
MIRT1551771	hsa-miR-4525	CLIP-seq
MIRT2053992	hsa-miR-4649-3p	CLIP-seq
MIRT1551772	hsa-miR-4665-5p	CLIP-seq
MIRT2053993	hsa-miR-4716-5p	CLIP-seq
MIRT1551773	hsa-miR-4723-5p	CLIP-seq
MIRT2053994	hsa-miR-4781-3p	CLIP-seq
MIRT2053995	hsa-miR-4796-3p	CLIP-seq
MIRT2053996	hsa-miR-501-3p	CLIP-seq
MIRT2053997	hsa-miR-502-3p	CLIP-seq
MIRT2053998	hsa-miR-5095	CLIP-seq
MIRT1551774	hsa-miR-625	CLIP-seq
MIRT1186426	hsa-miR-767-5p	CLIP-seq
MIRT2053999	hsa-miR-939	CLIP-seq
MIRT2283168	hsa-miR-1200	CLIP-seq
MIRT1186401	hsa-miR-122	CLIP-seq
MIRT1186402	hsa-miR-1224-3p	CLIP-seq
MIRT1186403	hsa-miR-1245	CLIP-seq
MIRT1186404	hsa-miR-1260	CLIP-seq
MIRT1186405	hsa-miR-1260b	CLIP-seq
MIRT1186407	hsa-miR-1280	CLIP-seq
MIRT1186409	hsa-miR-1297	CLIP-seq
MIRT1186413	hsa-miR-26a	CLIP-seq
MIRT1186414	hsa-miR-26b	CLIP-seq
MIRT2283169	hsa-miR-338-3p	CLIP-seq
MIRT2283170	hsa-miR-4294	CLIP-seq
MIRT2283171	hsa-miR-431	CLIP-seq
MIRT2283172	hsa-miR-4324	CLIP-seq
MIRT2283173	hsa-miR-4435	CLIP-seq
MIRT2053989	hsa-miR-4438	CLIP-seq
MIRT1186421	hsa-miR-4465	CLIP-seq
MIRT1186422	hsa-miR-4532	CLIP-seq
MIRT2283174	hsa-miR-4695-5p	CLIP-seq
MIRT2053998	hsa-miR-5095	CLIP-seq
MIRT1186424	hsa-miR-532-3p	CLIP-seq
MIRT2283175	hsa-miR-544b	CLIP-seq
MIRT1186426	hsa-miR-767-5p	CLIP-seq
MIRT2283176	hsa-miR-924	CLIP-seq
MIRT2391590	hsa-miR-4474-3p	CLIP-seq
MIRT1186426	hsa-miR-767-5p	CLIP-seq
MIRT2283168	hsa-miR-1200	CLIP-seq
MIRT1186402	hsa-miR-1224-3p	CLIP-seq
MIRT1186404	hsa-miR-1260	CLIP-seq
MIRT1186405	hsa-miR-1260b	CLIP-seq
MIRT1186407	hsa-miR-1280	CLIP-seq
MIRT2283172	hsa-miR-4324	CLIP-seq
MIRT2053989	hsa-miR-4438	CLIP-seq
MIRT2053998	hsa-miR-5095	CLIP-seq
MIRT1186424	hsa-miR-532-3p	CLIP-seq
MIRT2283175	hsa-miR-544b	CLIP-seq
MIRT2283168	hsa-miR-1200	CLIP-seq
MIRT1186402	hsa-miR-1224-3p	CLIP-seq
MIRT1186404	hsa-miR-1260	CLIP-seq
MIRT1186405	hsa-miR-1260b	CLIP-seq
MIRT1186407	hsa-miR-1280	CLIP-seq
MIRT2283172	hsa-miR-4324	CLIP-seq
MIRT2053989	hsa-miR-4438	CLIP-seq
MIRT2053996	hsa-miR-501-3p	CLIP-seq
MIRT2053997	hsa-miR-502-3p	CLIP-seq
MIRT2053998	hsa-miR-5095	CLIP-seq
MIRT1186424	hsa-miR-532-3p	CLIP-seq
MIRT2283175	hsa-miR-544b	CLIP-seq
MIRT1186426	hsa-miR-767-5p	CLIP-seq
MIRT2283168	hsa-miR-1200	CLIP-seq
MIRT1186402	hsa-miR-1224-3p	CLIP-seq
MIRT1186404	hsa-miR-1260	CLIP-seq
MIRT1186405	hsa-miR-1260b	CLIP-seq
MIRT1186407	hsa-miR-1280	CLIP-seq
MIRT2283172	hsa-miR-4324	CLIP-seq
MIRT2053989	hsa-miR-4438	CLIP-seq
MIRT2053998	hsa-miR-5095	CLIP-seq
MIRT1186424	hsa-miR-532-3p	CLIP-seq
MIRT2283175	hsa-miR-544b	CLIP-seq
MIRT1186426	hsa-miR-767-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0016020	Component	Membrane	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q17RQ9
• Protein name: NTPase KAP family P-loop domain-containing protein 1
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07693	KAP_NTPase	36 → 414	KAP family P-loop domain	Domain

• Sequence:

  MQQEAAQRESEELQHVQWRPRAVSGWGVPQLLWYLVFLQPIITEVHLRRRNVQFLFIRFS
  AWQYAGTDKLWAGLVTTLCEGIRRHYGALPFSVYSVLGNKPATRQDCCQSEWHCRRRVCL
  GLLALLAALGLGVGLLYLSLGGHALGHGSPSGSLLKVFGGAATTLSGSGLLMAVYSVGKH
  LFVSQRKKIERLVSREKFGSQLGFMCEVKKEVELLTDFLCFLEIYQRRRLRVVLEVTGLD
  TCYPERVVGVLNAINTLLSDSHAPFIFILVVDPSILAACLESAGNMKGTADNGYLFLNRT
  VTLPFSVPIMGRRTKLQFLHDAVQSRDDLLYREMTRKPWLPGDAGGESAQLLAVQAQAGT
  ERGQGRIDDEAARRIQEALFCLHDERDCLYEYVPDNVVSMRRIVNTVPITVRLLQQQQQQ
  GDFGGPTPRQAVAWVVLANQWPCRLSWALQCLEDRQQTGGAPEGRARLWDVFRDNSRELH
  TMTKALQNVLDLDGDPELFERFLGADFPFTVAEAQSLLRCTVNLDHSIRRRMGLIRAVSA
  LKPPSPPKSPTRDTPHAAHRANSASRAPPSGRASGQAGEGHHTGDLAHRGKLWPVACALF
  RPGQSSPGGP

• Sequence length: 610

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ALZHEIMER DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Relationship Type	References	Evidence Score
Ichthyosis Lamellar	Associate	38642798	★☆☆☆☆ Found in Text Mining only
Lamellar ichthyosis autosomal dominant form	Associate	38642798	★☆☆☆☆ Found in Text Mining only