CCDC57 (coiled-coil domain containing 57)

Gene

• Entrez ID: 284001
• Gene name: Coiled-coil domain containing 57
• Gene symbol: CCDC57
• Synonyms (NCBI Gene): -
• Chromosome: 17
• Chromosome location: 17q25.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT049379	hsa-miR-92a-3p	CLASH	23622248
MIRT869312	hsa-miR-1266	CLIP-seq
MIRT869313	hsa-miR-1291	CLIP-seq
MIRT869314	hsa-miR-1321	CLIP-seq
MIRT869315	hsa-miR-146b-3p	CLIP-seq
MIRT869316	hsa-miR-1914	CLIP-seq
MIRT869317	hsa-miR-296-5p	CLIP-seq
MIRT869318	hsa-miR-4270	CLIP-seq
MIRT869319	hsa-miR-4441	CLIP-seq
MIRT869320	hsa-miR-4506	CLIP-seq
MIRT869321	hsa-miR-4518	CLIP-seq
MIRT869322	hsa-miR-4739	CLIP-seq
MIRT869323	hsa-miR-4756-5p	CLIP-seq
MIRT1957907	hsa-miR-103a	CLIP-seq
MIRT1957908	hsa-miR-107	CLIP-seq
MIRT1957909	hsa-miR-15a	CLIP-seq
MIRT1957910	hsa-miR-15b	CLIP-seq
MIRT1957911	hsa-miR-16	CLIP-seq
MIRT1957912	hsa-miR-195	CLIP-seq
MIRT1957913	hsa-miR-214	CLIP-seq
MIRT1957914	hsa-miR-3122	CLIP-seq
MIRT1957915	hsa-miR-3619-5p	CLIP-seq
MIRT1957916	hsa-miR-3689a-3p	CLIP-seq
MIRT1957917	hsa-miR-3689c	CLIP-seq
MIRT1957918	hsa-miR-3913-5p	CLIP-seq
MIRT1957919	hsa-miR-424	CLIP-seq
MIRT1957920	hsa-miR-4291	CLIP-seq
MIRT1957921	hsa-miR-4300	CLIP-seq
MIRT1957922	hsa-miR-4310	CLIP-seq
MIRT1957923	hsa-miR-4763-5p	CLIP-seq
MIRT1957924	hsa-miR-497	CLIP-seq
MIRT1957925	hsa-miR-596	CLIP-seq
MIRT1957926	hsa-miR-761	CLIP-seq
MIRT1957927	hsa-miR-920	CLIP-seq
MIRT1957928	hsa-miR-922	CLIP-seq
MIRT1957907	hsa-miR-103a	CLIP-seq
MIRT1957908	hsa-miR-107	CLIP-seq
MIRT2194908	hsa-miR-1281	CLIP-seq
MIRT1957909	hsa-miR-15a	CLIP-seq
MIRT1957910	hsa-miR-15b	CLIP-seq
MIRT1957911	hsa-miR-16	CLIP-seq
MIRT1957912	hsa-miR-195	CLIP-seq
MIRT1957913	hsa-miR-214	CLIP-seq
MIRT1957914	hsa-miR-3122	CLIP-seq
MIRT1957915	hsa-miR-3619-5p	CLIP-seq
MIRT1957916	hsa-miR-3689a-3p	CLIP-seq
MIRT1957917	hsa-miR-3689c	CLIP-seq
MIRT1957918	hsa-miR-3913-5p	CLIP-seq
MIRT1957919	hsa-miR-424	CLIP-seq
MIRT1957920	hsa-miR-4291	CLIP-seq
MIRT1957921	hsa-miR-4300	CLIP-seq
MIRT1957922	hsa-miR-4310	CLIP-seq
MIRT2194909	hsa-miR-4704-3p	CLIP-seq
MIRT1957924	hsa-miR-497	CLIP-seq
MIRT1957926	hsa-miR-761	CLIP-seq
MIRT1957927	hsa-miR-920	CLIP-seq
MIRT1957928	hsa-miR-922	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000086	Process	G2/M transition of mitotic cell cycle	IDA	32402286
GO:0005515	Function	Protein binding	IPI	25416956, 25910212, 26871637, 32296183, 32402286, 36217029
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IDA	32402286
GO:0005813	Component	Centrosome	IEA
GO:0005814	Component	Centriole	IBA
GO:0005814	Component	Centriole	IDA	32402286
GO:0005814	Component	Centriole	IEA
GO:0005819	Component	Spindle	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005876	Component	Spindle microtubule	IBA
GO:0005876	Component	Spindle microtubule	IDA	32402286
GO:0007020	Process	Microtubule nucleation	IBA
GO:0007020	Process	Microtubule nucleation	IDA	32402286
GO:0007099	Process	Centriole replication	IBA
GO:0007099	Process	Centriole replication	IDA	32402286
GO:0034451	Component	Centriolar satellite	IBA
GO:0034451	Component	Centriolar satellite	IDA	32402286
GO:0034451	Component	Centriolar satellite	IEA
GO:0045931	Process	Positive regulation of mitotic cell cycle	IBA
GO:0045931	Process	Positive regulation of mitotic cell cycle	IDA	32402286
GO:0060271	Process	Cilium assembly	IBA
GO:0060271	Process	Cilium assembly	IDA	32402286

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q2TAC2
• Protein name: Coiled-coil domain-containing protein 57
• Protein function: Pleiotropic regulator of centriole duplication, mitosis, and ciliogenesis. Critical interface between centrosome and microtubule-mediated cellular processes. Centriole duplication protein required for recruitment of CEP63, CEP152, and PLK4 to th
• Sequence:

  MLPLGSEPALNELLLRKEEEWRALQAHRTQLQEAALQDTRSQLEEAQGKLRCLQEDFVYN
  LQVLEERDLELERYDAAFAQAREWEEARRAEVSELKIEAAKLRQALAREARKVEELQQQQ
  QLAFQEHRLELERVHSDKNGEIDHHREQYENLKWTLERKLEELDGELALQRQELLLEFES
  KMRKREHEFRLQADNMSNTALSRELKVKLLHKELEALKEAGAKAAESLQRAEATNAELER
  KLQSRAGELQDLEAMSRARVKDLEDKLHSVQLTRKKEEETFKRKHEELDRLAREKDAVLV
  AVKGAHVEQLQELQTRVLELQAHCETLEAQLRRAEWRQADTAKEKDAAIDQLREDASTVK
  SAWDAQIAQLSKEMVSRDLQIQTLQEEEVKLKAQVARSQQDIERYKQQLSLAVERERSLE
  RDQVQLGLDWQRRCDDIERDQIQKSEALIQGLSMAKSQVAAKLQETEQALQEQEVVLKAV
  TLERDQAVQALRMHGLPRPGAQMLLRQHEEEISKDFPSSEIQRLREQNTSLRNAIAQMRK
  EMEALSHQIPPPIQTAAESTDANQPDPEAGGDAATPDYVLALEAEIRTLKHKFKTLEKHL
  EDVLDPLKMSSPHAESQPSVRTSTETTGGSAQAGQAGGSVQAGQAGGSVQAGPVSSGLAL
  RKLGDRVQLLNLLVTRLRQKVLREPLEPAALQRELPREVDQVHLEVLELRKQVAELGKHL
  RIAQHGGAEPSGRKQPPASDAVALGREDAKSAEDEAPSRHLGKHQPRSAQVGSRLDALQG
  PKTQHSIHTVTCKSPRQKEDRSPKPPQAPQHPEEHGRQSHSSSSFASGTLQDMWRLLDLG
  SSPSGVTSQGDSTPELPAPPAADRRPVKMQAGIATPGMKTAAQAKAKTTGASRSHPAKAK
  GCQRPPKIRNYNIMD

• Sequence length: 915