PROX2 (prospero homeobox 2)

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein
Entrez ID 283571
Gene name Prospero homeobox 2
Gene symbol PROX2
Synonyms (NCBI Gene)
PROX-2
Chromosome 14
Chromosome location 14q24.3
miRNA miRNA information provided by mirtarbase database.
57
Gene miRNA Gene ontology Other IDs Protein
Show/Hide all (57)
miRTarBase ID miRNA Experiments Reference
MIRT018506 hsa-miR-335-5p Microarray 18185580
MIRT525437 hsa-miR-6782-3p PAR-CLIP 22012620
MIRT525436 hsa-miR-5000-5p PAR-CLIP 22012620
MIRT525435 hsa-miR-128-3p PAR-CLIP 22012620
MIRT525434 hsa-miR-216a-3p PAR-CLIP 22012620
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
20
Gene miRNA Gene ontology Other IDs Protein
Show/Hide all (20)
GO ID Ontology Definition Evidence Reference
GO:0000785 Component Chromatin ISA
GO:0000978 Function RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific ISA
GO:0003677 Function DNA binding IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein
MIM HGNC e!Ensembl
615094 26715 ENSG00000119608
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q3B8N5
Protein name Prospero homeobox protein 2 (Homeobox prospero-like protein PROX2) (PROX-2)
Protein function Transcription regulator. Does not seem to be essential for embryonic development and postnatal survival (By similarity).
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05044 HPD 439 → 592 Homeo-prospero domain Domain
Sequence 
MDPNSILLSPQPQICSHLAEACTEGERSSSPPELDRDSPFPWSQVPSSSPTDPEWFGDEH
IQAKRARVETIVRGMCLSPNPLVPGNAQAGVSPRCPKKARERKRKQNLPTPQGLLMPAPA
WDQGNRKGGPRVREQLHLLKQQLRHLQEHILQAAKPRDTAQGPGGCGTGKGPLSAKQGNG
CGPRPWVVDGDHQQGTSKDLSGAEKHQESEKPSFLPSGAPASLEILRKELTRAVSQAVDS
VLQKVLLDPPGHLTQLGRSFQGQVAEGRSEPSPPVGGACKDPLALAALPRRVQLQAGVPV
GNLSLAKRLDSPRYPIPPRMTPKPCQDPPANFPLTAPSHIQENQILSQLLGHRYNNGHWS
SSPPQDSSSQRHPSSEPALRPWRTTKPQPLVLSQQQCPLPFTSAHLESLPLLPSVKMEQR
GLHAVMEALPFSLLHIQEGLNPGHLKKAKLMFFFTRYPSSNLLKVYFPDVQFNRCITSQM
IKWFSNFREFYYIQMEKSARQAISDGVTNPKMLVVLRNSELFQALNMHYNKGNDFEVPDC
FLEIASLTLQEFFRAVSAGRDSDPSWKKPIYKIISKLDSDIPEIFKSSSYPQ
Sequence length 592
Interactions View interactions