Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
283349
Gene name Gene Name - the full gene name approved by the HGNC.
Ras association domain family member 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
RASSF3
Synonyms (NCBI Gene) Gene synonyms aliases
RASSF5
Chromosome Chromosome number
12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12q14.2
Summary Summary of gene provided in NCBI Entrez Gene.
The RAS oncogene (MIM 190020) is mutated in nearly one-third of all human cancers. Members of the RAS superfamily are plasma membrane GTP-binding proteins that modulate intracellular signal transduction pathways. A subfamily of RAS effectors, including RA
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT016387 hsa-miR-193b-3p Microarray 20304954
MIRT031332 hsa-miR-18a-5p Sequencing 20371350
MIRT038969 hsa-miR-20a-3p CLASH 23622248
MIRT1292752 hsa-miR-101 CLIP-seq
MIRT1292753 hsa-miR-1197 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 20920251, 23455922, 24255178, 24366813, 28514442, 32296183
GO:0005737 Component Cytoplasm IBA 21873635
GO:0005829 Component Cytosol IDA
GO:0005874 Component Microtubule IEA
GO:0005886 Component Plasma membrane IDA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
607019 14271 ENSG00000153179
Protein
UniProt ID Q86WH2
Protein name Ras association domain-containing protein 3
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00788 RA 79 187 Ras association (RalGDS/AF-6) domain Domain
PF16517 Nore1-SARAH 192 231 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Domain
Tissue specificity TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:11965544}.
Sequence
Sequence length 238
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Lung adenocarcinoma Adenocarcinoma of lung (disorder) rs28934576, rs121913530, rs397516975, rs587776805, rs121913469, rs121913364, rs121913351, rs121913366, rs397516896, rs397516977, rs397516981, rs397517127, rs121913344, rs727504233, rs121913370
View all (5 more)
28604730
Prostate cancer Prostate carcinoma, Prostate cancer, familial rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 29892016
Prostate cancer, hereditary PROSTATE CANCER, HEREDITARY, 1 rs387906327, rs193929331, rs74315365, rs397516896, rs794729219, rs121913349, rs587782641, rs1114167673, rs1597371666, rs2073394466 29892016
Associations from Text Mining
Disease Name Relationship Type References
Gastrointestinal Neoplasms Associate 32883271
Glaucoma Open Angle Associate 21310917
Low Tension Glaucoma Associate 23421332
Neoplasms Inhibit 24295637, 24367615
Oropharyngeal Neoplasms Associate 24295637
Squamous Cell Carcinoma of Head and Neck Associate 24295637