SLC22A24 (solute carrier family 22 member 24)

Gene
Gene Gene ontology Other IDs Protein
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
283238
Gene name Gene Name - the full gene name approved by the HGNC.
Solute carrier family 22 member 24
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
SLC22A24
Synonyms (NCBI Gene) Gene synonyms aliases
NET46
Chromosome Chromosome number
11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
11q12.3
Summary Summary of gene provided in NCBI Entrez Gene.
SLC22A24 belongs to a large family of transmembrane proteins that function as uniporters, symporters, and antiporters to transport organic ions across cell membranes (Jacobsson et al., 2007 [PubMed 17714910]).[supplied by OMIM, Mar 2008]
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Protein
Show/Hide all(5)
GO ID Ontology Definition Evidence Reference
GO:0008202 Process Steroid metabolic process IDA 31553721
GO:0015711 Process Organic anion transport IBA 21873635
GO:0016021 Component Integral component of membrane IEA
GO:0022857 Function Transmembrane transporter activity IEA
GO:0035382 Process Sterol transmembrane transport IDA 31553721
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Protein
MIM HGNC e!Ensembl
611698 28542 ENSG00000197658
Protein
Gene Gene ontology Other IDs Protein
UniProt ID Q8N4F4
Protein name Steroid transmembrane transporter SLC22A24 (Solute carrier family 22 member 24)
Protein function Renal transmembrane organic anion/dicarboxylate exchanger that participates in the reabsorption of conjugated steroids including estradiol-17beta-D-glucuronide (or 17beta-estradiol 17-O-(beta-D-glucuronate)), androstanediol glucuronide (or 5alph
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07690 MFS_1 16 → 312 Major Facilitator Superfamily Family
Tissue specificity TISSUE SPECIFICITY: [Isoform 1]: Localized to the kidney (PubMed:31553721). Highly specific expression pattern in the nephron, localized to segment 3 of the proximal tubule (PubMed:31553721). {ECO:0000269|PubMed:31553721}.; TISSUE SPECIFICITY: [Isoform 2]
Sequence 
MGFDVLLDQVGGMGRFQICLIAFFCITNILLFPNIVLENFTAFTPSHRCWVPLLDNDTVS
DNDTGTLSKDDLLRISIPLDSNLRPQKCQRFIHPQWQLLHLNGTFPNTNEPDTEPCVDGW
VYDRSSFLSTIVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDRVGRKIICKLCF
LQLAISNTCAAFAPTFLVYCILRFLAGFSTMTILGNTFILSLEWTLPRSRSMTIMVLLCS
YSVGQMLLGGLAFAIQDWHILQLTVSTPIIVLFLSSWKMVESARWLIINNQLDEGLKELR
RVAHINGKKNTEETLTTELVRSTMKKELDAVRIKTSIFSLFRAPKLRMRVFGLCFVRFAI
TVPFYGLILNLQHLGSNVSLFQILCGAVTFTARCVSLLTLNHMGRRISQILFTFPVGLFI
LVNTFLPQEMQILRVVLATLGIGSVSAASNSASVHHNELVPTILRSTVAGINAVSGRTGA
ALAPLLMTLMAYSPHLPWISYGVFPILAVPVILLLPETRDLPLPNTIQDVENDRKDSRNI
KQEDTCMKVTQF
Sequence length 552
Interactions View interactions