Gene Gene information from NCBI Gene database.
Entrez ID 283130
Gene name Solute carrier family 25 member 45
Gene symbol SLC25A45
Synonyms (NCBI Gene)
-
Chromosome 11
Chromosome location 11q13.1
Summary SLC25A45 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 [PubMed 16949250]).[supplied by OMIM, Mar 2008]
miRNA miRNA information provided by mirtarbase database.
546
miRTarBase ID miRNA Experiments Reference
MIRT503439 hsa-miR-890 HITS-CLIP 23706177
MIRT503438 hsa-miR-6808-5p HITS-CLIP 23706177
MIRT503437 hsa-miR-6893-5p HITS-CLIP 23706177
MIRT503436 hsa-miR-940 HITS-CLIP 23706177
MIRT503435 hsa-miR-3929 HITS-CLIP 23706177
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
6
GO ID Ontology Definition Evidence Reference
GO:0005739 Component Mitochondrion IBA
GO:0005739 Component Mitochondrion IEA
GO:0005743 Component Mitochondrial inner membrane IEA
GO:0016020 Component Membrane IEA
GO:0022857 Function Transmembrane transporter activity IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
610825 27442 ENSG00000162241
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8N413
Protein name Solute carrier family 25 member 45
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00153 Mito_carr 1 87 Mitochondrial carrier protein Family
PF00153 Mito_carr 95 195 Mitochondrial carrier protein Family
PF00153 Mito_carr 197 288 Mitochondrial carrier protein Family
Sequence
Sequence length 288
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
MELANOMA CTD
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Adenocarcinoma Mucinous Associate 26091520
★☆☆☆☆
Found in Text Mining only
Carcinoma Ovarian Epithelial Associate 26091520
★☆☆☆☆
Found in Text Mining only