Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID	2831
Gene name	Neuropeptides B and W receptor 1
Gene symbol	NPBWR1
Synonyms (NCBI Gene)	GPR7
Chromosome	8
Chromosome location	8q11.23

104

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miRTarBase ID	miRNA	Experiments	Reference
MIRT718355	hsa-miR-6805-5p	HITS-CLIP	19536157
MIRT718354	hsa-miR-6798-5p	HITS-CLIP	19536157
MIRT718353	hsa-miR-1292-3p	HITS-CLIP	19536157
MIRT718352	hsa-miR-3195	HITS-CLIP	19536157
MIRT718351	hsa-miR-4783-5p	HITS-CLIP	19536157
MIRT718350	hsa-miR-1237-5p	HITS-CLIP	19536157
MIRT718349	hsa-miR-4488	HITS-CLIP	19536157
MIRT718348	hsa-miR-4697-5p	HITS-CLIP	19536157
MIRT611211	hsa-miR-8485	HITS-CLIP	23824327
MIRT611209	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT611208	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT611207	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT611211	hsa-miR-8485	HITS-CLIP	23824327
MIRT611208	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT611207	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT611206	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT611211	hsa-miR-8485	HITS-CLIP	23824327
MIRT611209	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT611208	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT611207	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT611211	hsa-miR-8485	HITS-CLIP	23824327
MIRT611209	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT611208	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT611207	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT611211	hsa-miR-8485	HITS-CLIP	23824327
MIRT611209	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT611208	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT611207	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT611206	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT611211	hsa-miR-8485	HITS-CLIP	23824327
MIRT611209	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT611208	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT611207	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT611206	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT611211	hsa-miR-8485	HITS-CLIP	23824327
MIRT619951	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619950	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT619949	hsa-miR-603	HITS-CLIP	23824327
MIRT611209	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT611208	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT611207	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT619948	hsa-miR-3941	HITS-CLIP	23824327
MIRT611206	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT611211	hsa-miR-8485	HITS-CLIP	23824327
MIRT611209	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT611208	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT611207	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT611211	hsa-miR-8485	HITS-CLIP	23824327
MIRT611209	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT611208	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT611207	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT611206	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT718355	hsa-miR-6805-5p	HITS-CLIP	19536157
MIRT718354	hsa-miR-6798-5p	HITS-CLIP	19536157
MIRT718353	hsa-miR-1292-3p	HITS-CLIP	19536157
MIRT718352	hsa-miR-3195	HITS-CLIP	19536157
MIRT718351	hsa-miR-4783-5p	HITS-CLIP	19536157
MIRT718350	hsa-miR-1237-5p	HITS-CLIP	19536157
MIRT718349	hsa-miR-4488	HITS-CLIP	19536157
MIRT718348	hsa-miR-4697-5p	HITS-CLIP	19536157
MIRT611211	hsa-miR-8485	HITS-CLIP	23824327
MIRT611209	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT611208	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT611207	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT611211	hsa-miR-8485	HITS-CLIP	23824327
MIRT611208	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT611207	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT611206	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT611211	hsa-miR-8485	HITS-CLIP	23824327
MIRT611209	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT611208	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT611207	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT611211	hsa-miR-8485	HITS-CLIP	23824327
MIRT611209	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT611208	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT611207	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT611211	hsa-miR-8485	HITS-CLIP	23824327
MIRT611209	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT611208	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT611207	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT611206	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT611211	hsa-miR-8485	HITS-CLIP	23824327
MIRT611209	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT611208	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT611207	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT611206	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT611211	hsa-miR-8485	HITS-CLIP	23824327
MIRT619951	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619950	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT619949	hsa-miR-603	HITS-CLIP	23824327
MIRT611209	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT611208	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT611207	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT619948	hsa-miR-3941	HITS-CLIP	23824327
MIRT611206	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT611211	hsa-miR-8485	HITS-CLIP	23824327
MIRT611209	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT611208	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT611207	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT611211	hsa-miR-8485	HITS-CLIP	23824327
MIRT611209	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT611208	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT611207	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT611206	hsa-miR-4789-5p	HITS-CLIP	23824327

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GO ID	Ontology	Definition	Evidence	Reference
GO:0004930	Function	G protein-coupled receptor activity	IBA
GO:0004930	Function	G protein-coupled receptor activity	IEA
GO:0004985	Function	G protein-coupled opioid receptor activity	IEA
GO:0004985	Function	G protein-coupled opioid receptor activity	TAS	7590751
GO:0005515	Function	Protein binding	IPI	12401809, 32296183
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0007165	Process	Signal transduction	IEA
GO:0007186	Process	G protein-coupled receptor signaling pathway	IDA	12401809
GO:0007186	Process	G protein-coupled receptor signaling pathway	IEA
GO:0007218	Process	Neuropeptide signaling pathway	IBA
GO:0007268	Process	Chemical synaptic transmission	TAS	7590751
GO:0008188	Function	Neuropeptide receptor activity	IEA
GO:0016020	Component	Membrane	IC	12401809
GO:0016020	Component	Membrane	IEA
GO:0019222	Process	Regulation of metabolic process	IEA
GO:0038003	Process	G protein-coupled opioid receptor signaling pathway	IEA
GO:0042923	Function	Neuropeptide binding	IBA
GO:0043005	Component	Neuron projection	IBA
GO:0045202	Component	Synapse	IEA

MIM	HGNC	e!Ensembl
600730	4522	ENSG00000288611

P48145

Protein name

Neuropeptides B/W receptor type 1 (G-protein coupled receptor 7)

Protein function

Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00001	7tm_1	54 → 307	7 transmembrane receptor (rhodopsin family)	Family

Tissue specificity

TISSUE SPECIFICITY: Found in cerebellum and frontal cortex. Detected at high levels in hippocampus, amygdala and trachea; at moderate levels in fetal brain, pituitary gland and prostate. Not in caudate, accumbens, kidney or liver. Also detected at high le

Sequence

MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLY
VLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNT
FSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLD
DEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAK
ALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANS
CLNPFLYAFLDASFRRNLRQLITCRAAA

Sequence length

328

Interactions

View interactions

	KEGG		Reactome
	Neuroactive ligand-receptor interaction		Peptide ligand-binding receptors G alpha (i) signalling events

NPBWR1 (neuropeptides B and W receptor 1)