Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
28232
Gene name Gene Name - the full gene name approved by the HGNC.
Solute carrier organic anion transporter family member 3A1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
SLCO3A1
Synonyms (NCBI Gene) Gene synonyms aliases
OATP-D, OATP-RP3, OATP3A1, OATPD, OATPRP3, SLC21A11
Chromosome Chromosome number
15
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
15q26.1
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT024914 hsa-miR-215-5p Microarray 19074876
MIRT026667 hsa-miR-192-5p Microarray 19074876
MIRT051495 hsa-let-7e-5p CLASH 23622248
MIRT038665 hsa-miR-218-1-3p CLASH 23622248
MIRT699236 hsa-miR-6758-5p HITS-CLIP 23313552
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32296183
GO:0005886 Component Plasma membrane IDA 21278488
GO:0005886 Component Plasma membrane IEA
GO:0005886 Component Plasma membrane TAS
GO:0006811 Process Monoatomic ion transport IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
612435 10952 ENSG00000176463
Protein
UniProt ID Q9UIG8
Protein name Solute carrier organic anion transporter family member 3A1 (OATP3A1) (Organic anion transporter polypeptide-related protein 3) (OATP-RP3) (OATPRP3) (Organic anion-transporting polypeptide D) (OATP-D) (PGE1 transporter) (Sodium-independent organic anion tr
Protein function Putative organic anion antiporter with apparent broad substrate specificity. Recognizes various substrates including thyroid hormone L-thyroxine, prostanoids such as prostaglandin E1 and E2, bile acids such as taurocholate, glycolate and glycoch
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03137 OATP 41 622 Organic Anion Transporter Polypeptide (OATP) family Family
PF07648 Kazal_2 472 513 Kazal-type serine protease inhibitor domain Domain
Tissue specificity TISSUE SPECIFICITY: Generally the expression of isoform 1 is higher than that of isoform 2. {ECO:0000269|PubMed:16971491}.; TISSUE SPECIFICITY: [Isoform 1]: Expressed in placental trophoblasts (PubMed:10873595, PubMed:12409283). Expressed in pancreas, kid
Sequence
Sequence length 710
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Transport of organic anions
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Dementia Dementia N/A N/A GWAS
Hypertension Hypertension (confirmatory factor analysis Factor 12) N/A N/A GWAS
Insomnia Insomnia N/A N/A GWAS
Metabolic Syndrome Metabolic syndrome N/A N/A GWAS
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
3C syndrome Stimulate 21383546
Antisocial Personality Disorder Associate 37756443
Carcinoma Hepatocellular Associate 21383546
Cholestasis Stimulate 34971708
Colonic Neoplasms Associate 21383546
Corneal Perforation Associate 24945726
Crohn Disease Associate 24945726
Inflammation Associate 24945726, 40076698
Intestinal Perforation Associate 24945726
Intrahepatic Cholestasis of Pregnancy Associate 34638773