GNS (glucosamine (N-acetyl)-6-sulfatase)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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2799 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Glucosamine (N-acetyl)-6-sulfatase |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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GNS |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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G6S |
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Chromosome
Chromosome number
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12 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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12q14.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | P15586 | ||||||||||
| Protein name | N-acetylglucosamine-6-sulfatase (EC 3.1.6.14) (Glucosamine-6-sulfatase) (G6S) | ||||||||||
| Protein function | Hydrolyzes 6-sulfate groups in N-acetyl-d-glucosaminide units of heparin sulfate and keratan sulfate. | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 552 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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