GNAI1 (G protein subunit alpha i1)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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2770 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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G protein subunit alpha i1 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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GNAI1 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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Gi, HG1B, NEDHISB |
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Chromosome
Chromosome number
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7 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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7q21.11 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. The alpha subunit binds guanine nucleotide, can hydrolyze GTP, and can interact with other proteins. The protein encoded by |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | P63096 | ||||||||||
| Protein name | Guanine nucleotide-binding protein G(i) subunit alpha-1 (EC 3.6.5.-) (Adenylate cyclase-inhibiting G alpha protein) | ||||||||||
| Protein function | Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades (PubMed:18434541, PubMed:33762731, PubMed:34239069, PubMed:35610220, PubMed:37935376, PubMe | ||||||||||
| PDB | 1KJY , 1Y3A , 2G83 , 2GTP , 2IK8 , 2OM2 , 2XNS , 3ONW , 3QE0 , 3QI2 , 3UMR , 3UMS , 4G5Q , 5JS7 , 5JS8 , 5TDH , 6CMO , 6CRK , 6DDE , 6DDF , 6KPF , 6KPG , 6LFM , 6LFO , 6LML , 6N4B , 6OMM , 6OS9 , 6OSA , 6OT0 , 6PB0 , 6PB1 , 6PT0 , 6QNO , 6VU8 , 6XBJ , 6XBK , 6XBL , 6XBM , 7CMU , 7CMV , 7DB6 , 7DW9 , 7E2X , 7E2Y , 7E2Z , 7E32 , 7E33 , 7E9G , 7EB2 , 7EJX | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 354 | ||||||||||
| Interactions | View interactions | ||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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