Gene Gene information from NCBI Gene database.
Entrez ID 2768
Gene name G protein subunit alpha 12
Gene symbol GNA12
Synonyms (NCBI Gene)
HG1M1NNX3RMPgep
Chromosome 7
Chromosome location 7p22.3-p22.2
miRNA miRNA information provided by mirtarbase database.
614
miRTarBase ID miRNA Experiments Reference
MIRT023075 hsa-miR-124-3p Microarray 18668037
MIRT027790 hsa-miR-98-5p Microarray 19088304
MIRT028098 hsa-miR-93-5p Sequencing 20371350
MIRT046311 hsa-miR-23b-3p CLASH 23622248
MIRT045616 hsa-miR-149-5p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
56
GO ID Ontology Definition Evidence Reference
GO:0000166 Function Nucleotide binding IEA
GO:0001664 Function G protein-coupled receptor binding IEA
GO:0001701 Process In utero embryonic development IEA
GO:0003924 Function GTPase activity IBA
GO:0003924 Function GTPase activity IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
604394 4380 ENSG00000146535
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q03113
Protein name Guanine nucleotide-binding protein subunit alpha-12 (G alpha-12) (G-protein subunit alpha-12)
Protein function Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (PubMed:12515866, PubMed:15240885, PubMed:15525651, PubMed:16705036, PubMed:16787920, PubMed:17565996, PubMed:2
PDB 7YDJ
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00503 G-alpha 37 370 G-protein alpha subunit Domain
Sequence
Sequence length 381
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  MAPK signaling pathway
cGMP-PKG signaling pathway
Sphingolipid signaling pathway
Phospholipase D signaling pathway
Hormone signaling
Vascular smooth muscle contraction
Long-term depression
Regulation of actin cytoskeleton
Parathyroid hormone synthesis, secretion and action
Pathogenic Escherichia coli infection
Human cytomegalovirus infection
Pathways in cancer
  G alpha (12/13) signalling events
Thrombin signalling through proteinase activated receptors (PARs)