Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	27430
Gene name	Methionine adenosyltransferase 2 non-catalytic beta subunit
Gene symbol	MAT2B
Synonyms (NCBI Gene)	MAT-IIMATIIbetaNbla02999SDR23E1TGR
Chromosome	5
Chromosome location	5q34
Summary	The protein encoded by this gene belongs to the methionine adenosyltransferase (MAT) family. MAT catalyzes the biosynthesis of S-adenosylmethionine from methionine and ATP. This protein is the regulatory beta subunit of MAT. Alternative splicing results i

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Show/Hide all (304)

miRTarBase ID	miRNA	Experiments	Reference
MIRT019945	hsa-miR-375	Microarray	20215506
MIRT020796	hsa-miR-155-5p	Proteomics	18668040
MIRT029818	hsa-miR-26b-5p	Microarray	19088304
MIRT032407	hsa-let-7b-5p	Proteomics	18668040
MIRT437430	hsa-miR-21-3p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	24098708
MIRT437430	hsa-miR-21-3p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	24098708
MIRT543363	hsa-miR-5692a	PAR-CLIP	21572407
MIRT543362	hsa-miR-377-3p	PAR-CLIP	21572407
MIRT543363	hsa-miR-5692a	PAR-CLIP	21572407
MIRT543362	hsa-miR-377-3p	PAR-CLIP	21572407
MIRT1133628	hsa-miR-1202	CLIP-seq
MIRT1133629	hsa-miR-130a	CLIP-seq
MIRT1133630	hsa-miR-130b	CLIP-seq
MIRT1133631	hsa-miR-1323	CLIP-seq
MIRT1133632	hsa-miR-203	CLIP-seq
MIRT1133633	hsa-miR-2116	CLIP-seq
MIRT1133634	hsa-miR-300	CLIP-seq
MIRT1133635	hsa-miR-301a	CLIP-seq
MIRT1133636	hsa-miR-301b	CLIP-seq
MIRT1133637	hsa-miR-3121-5p	CLIP-seq
MIRT1133638	hsa-miR-3194-5p	CLIP-seq
MIRT1133639	hsa-miR-323b-3p	CLIP-seq
MIRT1133640	hsa-miR-335	CLIP-seq
MIRT1133641	hsa-miR-34c-3p	CLIP-seq
MIRT1133642	hsa-miR-3613-3p	CLIP-seq
MIRT1133643	hsa-miR-3666	CLIP-seq
MIRT1133644	hsa-miR-377	CLIP-seq
MIRT1133645	hsa-miR-381	CLIP-seq
MIRT1133646	hsa-miR-3972	CLIP-seq
MIRT1133647	hsa-miR-3974	CLIP-seq
MIRT1133648	hsa-miR-421	CLIP-seq
MIRT1133649	hsa-miR-4273	CLIP-seq
MIRT1133650	hsa-miR-4295	CLIP-seq
MIRT1133651	hsa-miR-4321	CLIP-seq
MIRT1133652	hsa-miR-4530	CLIP-seq
MIRT1133653	hsa-miR-454	CLIP-seq
MIRT1133654	hsa-miR-4666-5p	CLIP-seq
MIRT1133655	hsa-miR-4668-3p	CLIP-seq
MIRT1133656	hsa-miR-4671-3p	CLIP-seq
MIRT1133657	hsa-miR-4677-5p	CLIP-seq
MIRT1133658	hsa-miR-4696	CLIP-seq
MIRT1133659	hsa-miR-4709-5p	CLIP-seq
MIRT1133660	hsa-miR-4729	CLIP-seq
MIRT1133661	hsa-miR-4766-5p	CLIP-seq
MIRT1133662	hsa-miR-4795-3p	CLIP-seq
MIRT1133663	hsa-miR-485-3p	CLIP-seq
MIRT1133664	hsa-miR-505	CLIP-seq
MIRT1133665	hsa-miR-513c	CLIP-seq
MIRT1133666	hsa-miR-514b-5p	CLIP-seq
MIRT1133667	hsa-miR-548a-3p	CLIP-seq
MIRT1133668	hsa-miR-548ac	CLIP-seq
MIRT1133669	hsa-miR-548ae	CLIP-seq
MIRT1133670	hsa-miR-548aj	CLIP-seq
MIRT1133671	hsa-miR-548am	CLIP-seq
MIRT1133672	hsa-miR-548c-3p	CLIP-seq
MIRT1133673	hsa-miR-548d-3p	CLIP-seq
MIRT1133674	hsa-miR-548e	CLIP-seq
MIRT1133675	hsa-miR-548f	CLIP-seq
MIRT1133676	hsa-miR-548g	CLIP-seq
MIRT1133677	hsa-miR-548o	CLIP-seq
MIRT1133678	hsa-miR-548x	CLIP-seq
MIRT1133679	hsa-miR-548z	CLIP-seq
MIRT1133680	hsa-miR-653	CLIP-seq
MIRT1133681	hsa-miR-656	CLIP-seq
MIRT1133629	hsa-miR-130a	CLIP-seq
MIRT1133630	hsa-miR-130b	CLIP-seq
MIRT1133635	hsa-miR-301a	CLIP-seq
MIRT1133636	hsa-miR-301b	CLIP-seq
MIRT1133682	hsa-miR-3145-5p	CLIP-seq
MIRT1133640	hsa-miR-335	CLIP-seq
MIRT1133641	hsa-miR-34c-3p	CLIP-seq
MIRT1133643	hsa-miR-3666	CLIP-seq
MIRT1133683	hsa-miR-3691-3p	CLIP-seq
MIRT1133684	hsa-miR-371-5p	CLIP-seq
MIRT1133685	hsa-miR-4253	CLIP-seq
MIRT1133650	hsa-miR-4295	CLIP-seq
MIRT1133651	hsa-miR-4321	CLIP-seq
MIRT1133686	hsa-miR-4436a	CLIP-seq
MIRT1133653	hsa-miR-454	CLIP-seq
MIRT1133687	hsa-miR-4662a-5p	CLIP-seq
MIRT1133656	hsa-miR-4671-3p	CLIP-seq
MIRT1133688	hsa-miR-4676-5p	CLIP-seq
MIRT1133658	hsa-miR-4696	CLIP-seq
MIRT1133660	hsa-miR-4729	CLIP-seq
MIRT1133689	hsa-miR-4761-3p	CLIP-seq
MIRT1133690	hsa-miR-4789-3p	CLIP-seq
MIRT1133691	hsa-miR-575	CLIP-seq
MIRT1133692	hsa-miR-888	CLIP-seq
MIRT1133693	hsa-miR-938	CLIP-seq
MIRT1133629	hsa-miR-130a	CLIP-seq
MIRT1133630	hsa-miR-130b	CLIP-seq
MIRT1133635	hsa-miR-301a	CLIP-seq
MIRT1133636	hsa-miR-301b	CLIP-seq
MIRT1133640	hsa-miR-335	CLIP-seq
MIRT1133643	hsa-miR-3666	CLIP-seq
MIRT1133650	hsa-miR-4295	CLIP-seq
MIRT1133653	hsa-miR-454	CLIP-seq
MIRT1133658	hsa-miR-4696	CLIP-seq
MIRT1133660	hsa-miR-4729	CLIP-seq
MIRT1133661	hsa-miR-4766-5p	CLIP-seq
MIRT1133631	hsa-miR-1323	CLIP-seq
MIRT2038022	hsa-miR-139-5p	CLIP-seq
MIRT2038023	hsa-miR-3120-3p	CLIP-seq
MIRT1133641	hsa-miR-34c-3p	CLIP-seq
MIRT2038024	hsa-miR-3618	CLIP-seq
MIRT2038025	hsa-miR-3671	CLIP-seq
MIRT1133684	hsa-miR-371-5p	CLIP-seq
MIRT2038026	hsa-miR-371b-5p	CLIP-seq
MIRT2038027	hsa-miR-3977	CLIP-seq
MIRT1133651	hsa-miR-4321	CLIP-seq
MIRT2038028	hsa-miR-4522	CLIP-seq
MIRT2038029	hsa-miR-4686	CLIP-seq
MIRT1133661	hsa-miR-4766-5p	CLIP-seq
MIRT2038030	hsa-miR-4793-5p	CLIP-seq
MIRT1133662	hsa-miR-4795-3p	CLIP-seq
MIRT1133663	hsa-miR-485-3p	CLIP-seq
MIRT2038031	hsa-miR-548a-5p	CLIP-seq
MIRT2038032	hsa-miR-548ab	CLIP-seq
MIRT2038033	hsa-miR-548ak	CLIP-seq
MIRT2038034	hsa-miR-548b-5p	CLIP-seq
MIRT2038035	hsa-miR-548c-5p	CLIP-seq
MIRT2038036	hsa-miR-548d-5p	CLIP-seq
MIRT2038037	hsa-miR-548h	CLIP-seq
MIRT2038038	hsa-miR-548i	CLIP-seq
MIRT2038039	hsa-miR-548j	CLIP-seq
MIRT2038040	hsa-miR-548k	CLIP-seq
MIRT2038041	hsa-miR-548l	CLIP-seq
MIRT1133677	hsa-miR-548o	CLIP-seq
MIRT2038042	hsa-miR-548w	CLIP-seq
MIRT2038043	hsa-miR-548y	CLIP-seq
MIRT2038044	hsa-miR-559	CLIP-seq
MIRT1133681	hsa-miR-656	CLIP-seq
MIRT2038045	hsa-miR-922	CLIP-seq
MIRT2267986	hsa-miR-106a	CLIP-seq
MIRT2267987	hsa-miR-106b	CLIP-seq
MIRT2267988	hsa-miR-1227	CLIP-seq
MIRT1133629	hsa-miR-130a	CLIP-seq
MIRT1133630	hsa-miR-130b	CLIP-seq
MIRT1133631	hsa-miR-1323	CLIP-seq
MIRT2038022	hsa-miR-139-5p	CLIP-seq
MIRT2267989	hsa-miR-17	CLIP-seq
MIRT2267990	hsa-miR-20a	CLIP-seq
MIRT2267991	hsa-miR-20b	CLIP-seq
MIRT1133633	hsa-miR-2116	CLIP-seq
MIRT1133635	hsa-miR-301a	CLIP-seq
MIRT1133636	hsa-miR-301b	CLIP-seq
MIRT2267992	hsa-miR-3064-3p	CLIP-seq
MIRT2038023	hsa-miR-3120-3p	CLIP-seq
MIRT2267993	hsa-miR-3140-5p	CLIP-seq
MIRT1133640	hsa-miR-335	CLIP-seq
MIRT1133641	hsa-miR-34c-3p	CLIP-seq
MIRT1133642	hsa-miR-3613-3p	CLIP-seq
MIRT2038024	hsa-miR-3618	CLIP-seq
MIRT2267994	hsa-miR-3647-3p	CLIP-seq
MIRT1133643	hsa-miR-3666	CLIP-seq
MIRT2267995	hsa-miR-3689d	CLIP-seq
MIRT1133684	hsa-miR-371-5p	CLIP-seq
MIRT1133644	hsa-miR-377	CLIP-seq
MIRT1133647	hsa-miR-3974	CLIP-seq
MIRT2038027	hsa-miR-3977	CLIP-seq
MIRT1133648	hsa-miR-421	CLIP-seq
MIRT1133649	hsa-miR-4273	CLIP-seq
MIRT1133650	hsa-miR-4295	CLIP-seq
MIRT1133651	hsa-miR-4321	CLIP-seq
MIRT1133653	hsa-miR-454	CLIP-seq
MIRT1133687	hsa-miR-4662a-5p	CLIP-seq
MIRT1133655	hsa-miR-4668-3p	CLIP-seq
MIRT1133656	hsa-miR-4671-3p	CLIP-seq
MIRT1133688	hsa-miR-4676-5p	CLIP-seq
MIRT1133657	hsa-miR-4677-5p	CLIP-seq
MIRT2038029	hsa-miR-4686	CLIP-seq
MIRT1133658	hsa-miR-4696	CLIP-seq
MIRT1133659	hsa-miR-4709-5p	CLIP-seq
MIRT1133660	hsa-miR-4729	CLIP-seq
MIRT1133661	hsa-miR-4766-5p	CLIP-seq
MIRT1133690	hsa-miR-4789-3p	CLIP-seq
MIRT2038030	hsa-miR-4793-5p	CLIP-seq
MIRT1133662	hsa-miR-4795-3p	CLIP-seq
MIRT2267996	hsa-miR-4802-5p	CLIP-seq
MIRT1133663	hsa-miR-485-3p	CLIP-seq
MIRT2267997	hsa-miR-496	CLIP-seq
MIRT1133664	hsa-miR-505	CLIP-seq
MIRT1133665	hsa-miR-513c	CLIP-seq
MIRT1133666	hsa-miR-514b-5p	CLIP-seq
MIRT2267998	hsa-miR-519d	CLIP-seq
MIRT1133667	hsa-miR-548a-3p	CLIP-seq
MIRT2038031	hsa-miR-548a-5p	CLIP-seq
MIRT2038032	hsa-miR-548ab	CLIP-seq
MIRT1133668	hsa-miR-548ac	CLIP-seq
MIRT1133669	hsa-miR-548ae	CLIP-seq
MIRT1133670	hsa-miR-548aj	CLIP-seq
MIRT2038033	hsa-miR-548ak	CLIP-seq
MIRT1133671	hsa-miR-548am	CLIP-seq
MIRT2038034	hsa-miR-548b-5p	CLIP-seq
MIRT1133672	hsa-miR-548c-3p	CLIP-seq
MIRT2038035	hsa-miR-548c-5p	CLIP-seq
MIRT1133673	hsa-miR-548d-3p	CLIP-seq
MIRT2038036	hsa-miR-548d-5p	CLIP-seq
MIRT1133674	hsa-miR-548e	CLIP-seq
MIRT1133675	hsa-miR-548f	CLIP-seq
MIRT1133676	hsa-miR-548g	CLIP-seq
MIRT2038037	hsa-miR-548h	CLIP-seq
MIRT2038038	hsa-miR-548i	CLIP-seq
MIRT2038039	hsa-miR-548j	CLIP-seq
MIRT2038040	hsa-miR-548k	CLIP-seq
MIRT2038041	hsa-miR-548l	CLIP-seq
MIRT1133677	hsa-miR-548o	CLIP-seq
MIRT2267999	hsa-miR-548t	CLIP-seq
MIRT2038042	hsa-miR-548w	CLIP-seq
MIRT1133678	hsa-miR-548x	CLIP-seq
MIRT2038043	hsa-miR-548y	CLIP-seq
MIRT1133679	hsa-miR-548z	CLIP-seq
MIRT2038044	hsa-miR-559	CLIP-seq
MIRT1133691	hsa-miR-575	CLIP-seq
MIRT2038045	hsa-miR-922	CLIP-seq
MIRT2268000	hsa-miR-93	CLIP-seq
MIRT1133629	hsa-miR-130a	CLIP-seq
MIRT1133630	hsa-miR-130b	CLIP-seq
MIRT2431032	hsa-miR-142-5p	CLIP-seq
MIRT1133635	hsa-miR-301a	CLIP-seq
MIRT1133636	hsa-miR-301b	CLIP-seq
MIRT1133682	hsa-miR-3145-5p	CLIP-seq
MIRT2431033	hsa-miR-3200-5p	CLIP-seq
MIRT2431034	hsa-miR-330-3p	CLIP-seq
MIRT1133640	hsa-miR-335	CLIP-seq
MIRT2431035	hsa-miR-3662	CLIP-seq
MIRT1133643	hsa-miR-3666	CLIP-seq
MIRT2431036	hsa-miR-3670	CLIP-seq
MIRT1133683	hsa-miR-3691-3p	CLIP-seq
MIRT2431037	hsa-miR-4269	CLIP-seq
MIRT1133650	hsa-miR-4295	CLIP-seq
MIRT2431038	hsa-miR-4303	CLIP-seq
MIRT1133686	hsa-miR-4436a	CLIP-seq
MIRT2431039	hsa-miR-4514	CLIP-seq
MIRT1133653	hsa-miR-454	CLIP-seq
MIRT2431040	hsa-miR-4659a-3p	CLIP-seq
MIRT2431041	hsa-miR-4659b-3p	CLIP-seq
MIRT1133687	hsa-miR-4662a-5p	CLIP-seq
MIRT1133656	hsa-miR-4671-3p	CLIP-seq
MIRT1133688	hsa-miR-4676-5p	CLIP-seq
MIRT2431042	hsa-miR-4692	CLIP-seq
MIRT1133658	hsa-miR-4696	CLIP-seq
MIRT2431043	hsa-miR-4698	CLIP-seq
MIRT1133660	hsa-miR-4729	CLIP-seq
MIRT2431044	hsa-miR-4742-5p	CLIP-seq
MIRT1133661	hsa-miR-4766-5p	CLIP-seq
MIRT2431045	hsa-miR-561	CLIP-seq
MIRT1133691	hsa-miR-575	CLIP-seq
MIRT2038025	hsa-miR-3671	CLIP-seq
MIRT1133684	hsa-miR-371-5p	CLIP-seq
MIRT2038026	hsa-miR-371b-5p	CLIP-seq
MIRT2438540	hsa-miR-4477b	CLIP-seq
MIRT2038028	hsa-miR-4522	CLIP-seq
MIRT1133631	hsa-miR-1323	CLIP-seq
MIRT1133633	hsa-miR-2116	CLIP-seq
MIRT2567689	hsa-miR-217	CLIP-seq
MIRT1133637	hsa-miR-3121-5p	CLIP-seq
MIRT1133682	hsa-miR-3145-5p	CLIP-seq
MIRT2431035	hsa-miR-3662	CLIP-seq
MIRT2038025	hsa-miR-3671	CLIP-seq
MIRT1133683	hsa-miR-3691-3p	CLIP-seq
MIRT1133684	hsa-miR-371-5p	CLIP-seq
MIRT2038026	hsa-miR-371b-5p	CLIP-seq
MIRT1133685	hsa-miR-4253	CLIP-seq
MIRT1133649	hsa-miR-4273	CLIP-seq
MIRT2567690	hsa-miR-4418	CLIP-seq
MIRT1133686	hsa-miR-4436a	CLIP-seq
MIRT2438540	hsa-miR-4477b	CLIP-seq
MIRT2038028	hsa-miR-4522	CLIP-seq
MIRT1133687	hsa-miR-4662a-5p	CLIP-seq
MIRT1133688	hsa-miR-4676-5p	CLIP-seq
MIRT1133657	hsa-miR-4677-5p	CLIP-seq
MIRT2431043	hsa-miR-4698	CLIP-seq
MIRT2567691	hsa-miR-4699-3p	CLIP-seq
MIRT1133689	hsa-miR-4761-3p	CLIP-seq
MIRT1133663	hsa-miR-485-3p	CLIP-seq
MIRT2567692	hsa-miR-509-3-5p	CLIP-seq
MIRT2567693	hsa-miR-509-5p	CLIP-seq
MIRT1133677	hsa-miR-548o	CLIP-seq
MIRT1133691	hsa-miR-575	CLIP-seq
MIRT1133692	hsa-miR-888	CLIP-seq
MIRT1133693	hsa-miR-938	CLIP-seq
MIRT2567689	hsa-miR-217	CLIP-seq
MIRT1133682	hsa-miR-3145-5p	CLIP-seq
MIRT2431035	hsa-miR-3662	CLIP-seq
MIRT2038025	hsa-miR-3671	CLIP-seq
MIRT1133683	hsa-miR-3691-3p	CLIP-seq
MIRT1133684	hsa-miR-371-5p	CLIP-seq
MIRT2038026	hsa-miR-371b-5p	CLIP-seq
MIRT1133685	hsa-miR-4253	CLIP-seq
MIRT2567690	hsa-miR-4418	CLIP-seq
MIRT1133686	hsa-miR-4436a	CLIP-seq
MIRT2438540	hsa-miR-4477b	CLIP-seq
MIRT2038028	hsa-miR-4522	CLIP-seq
MIRT1133687	hsa-miR-4662a-5p	CLIP-seq
MIRT1133688	hsa-miR-4676-5p	CLIP-seq
MIRT2431043	hsa-miR-4698	CLIP-seq
MIRT2567691	hsa-miR-4699-3p	CLIP-seq
MIRT1133689	hsa-miR-4761-3p	CLIP-seq
MIRT2567692	hsa-miR-509-3-5p	CLIP-seq
MIRT2567693	hsa-miR-509-5p	CLIP-seq
MIRT1133691	hsa-miR-575	CLIP-seq
MIRT1133692	hsa-miR-888	CLIP-seq
MIRT1133693	hsa-miR-938	CLIP-seq

Show/Hide all (1)

Transcription factor	Regulation	Reference
SP1	Activation	11337507

Show/Hide all (15)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25075345, 25416956, 32296183, 32353859, 33060197, 33961781, 36217030
GO:0005634	Component	Nucleus	HDA	21630459
GO:0005634	Component	Nucleus	IDA
GO:0005829	Component	Cytosol	TAS
GO:0006556	Process	S-adenosylmethionine biosynthetic process	IBA
GO:0006556	Process	S-adenosylmethionine biosynthetic process	IDA	10644686, 25075345
GO:0006556	Process	S-adenosylmethionine biosynthetic process	IEA
GO:0006730	Process	One-carbon metabolic process	IEA
GO:0019899	Function	Enzyme binding	IPI	10644686
GO:0048269	Component	Methionine adenosyltransferase complex	IBA
GO:0048269	Component	Methionine adenosyltransferase complex	IDA	10644686, 25075345
GO:0048269	Component	Methionine adenosyltransferase complex	IPI	25075345
GO:0048270	Function	Methionine adenosyltransferase regulator activity	IBA
GO:0048270	Function	Methionine adenosyltransferase regulator activity	IDA	10644686, 25075345
GO:0070062	Component	Extracellular exosome	HDA	23533145

MIM	HGNC	e!Ensembl
605527	6905	ENSG00000038274

Q9NZL9

Protein name

Methionine adenosyltransferase 2 subunit beta (Methionine adenosyltransferase II beta) (MAT II beta) (Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase)

Protein function

Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L

PDB

2YDX , 2YDY , 4KTT , 4KTV , 4NDN

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04321	RmlD_sub_bind	29 → 324	RmlD substrate binding domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:10644686, ECO:0000269|PubMed:11337507}.

Sequence

MVGREKELSIHFVPGSCRLVEEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGF
RRARPKFEQVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNL
AKEAAAVGAFLIYISSDYVFDGTNPPYREEDIPAPLNLYGKTKLDGEKAVLENNLGAAVL
RIPILYGEVEKLEESAVTVMFDKVQFSNKSANMDHWQQRFPTHVKDVATVCRQLAEKRML
DPSIKGTFHWSGNEQMTKYEMACAIADAFNLPSSHLRPITDSPVLGAQRPRNAQLDCSKL
ETLGIGQRTPFRIGIKESLWPFLIDKRWRQTVFH

Sequence length

334

Interactions

View interactions

	KEGG		Reactome
	Cysteine and methionine metabolism One carbon pool by folate Metabolic pathways Biosynthesis of amino acids Biosynthesis of cofactors		Methylation Ub-specific processing proteases

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (5)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ATTENTION DEFICIT HYPERACTIVITY DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEMENTIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HUMAN PAPILLOMA VIRUS INFECTION	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OROPHARYNX CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SUBSTANCE ABUSE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (10)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Breast Neoplasms	Associate	38116315	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Associate	18045590, 20421296, 23814050, 24098708, 25794709	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Non Small Cell Lung	Stimulate	34288814	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Associate	23325601, 25794709	★★★★★ ★☆☆☆☆ Found in Text Mining only
Leiomyoma	Associate	30196971	★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver Failure	Associate	25794709	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malformations of Cortical Development Group I	Associate	18045590	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Associate	18698677, 19025580, 24098708, 25794709, 25921176, 30379973	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Stimulate	34288814	★★★★★ ★☆☆☆☆ Found in Text Mining only
Urinary Bladder Neoplasms	Associate	25921176	★★★★★ ★☆☆☆☆ Found in Text Mining only

MAT2B (methionine adenosyltransferase 2 non-catalytic beta subunit)