Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	27342
Gene name Gene Name - the full gene name approved by the HGNC.	RAB guanine nucleotide exchange factor 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	RABGEF1
Synonyms (NCBI Gene) Gene synonyms aliases	RABEX5, RAP1, rabex-5
Chromosome Chromosome number	7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	7q11.21
Summary Summary of gene provided in NCBI Entrez Gene.	RABGEF1 forms a complex with rabaptin-5 (RABPT5; MIM 603616) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor (GEF) for RAB5 (RAB5A; MIM 179512) (Horiuchi et al., 1997 [PubMed 9323142]).[suppli

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miRTarBase ID	miRNA	Experiments	Reference
MIRT023256	hsa-miR-122-5p	Microarray	17612493
MIRT700311	hsa-miR-6508-5p	HITS-CLIP	23313552
MIRT700310	hsa-miR-8067	HITS-CLIP	23313552
MIRT700309	hsa-miR-4795-5p	HITS-CLIP	23313552
MIRT700308	hsa-miR-5687	HITS-CLIP	23313552
MIRT700307	hsa-miR-518d-5p	HITS-CLIP	23313552
MIRT700306	hsa-miR-518e-5p	HITS-CLIP	23313552
MIRT700305	hsa-miR-518f-5p	HITS-CLIP	23313552
MIRT700304	hsa-miR-519a-5p	HITS-CLIP	23313552
MIRT700303	hsa-miR-519b-5p	HITS-CLIP	23313552
MIRT700302	hsa-miR-519c-5p	HITS-CLIP	23313552
MIRT700301	hsa-miR-520c-5p	HITS-CLIP	23313552
MIRT700300	hsa-miR-522-5p	HITS-CLIP	23313552
MIRT700299	hsa-miR-523-5p	HITS-CLIP	23313552
MIRT700298	hsa-miR-526a	HITS-CLIP	23313552
MIRT700297	hsa-miR-4777-5p	HITS-CLIP	23313552
MIRT700296	hsa-miR-3616-5p	HITS-CLIP	23313552
MIRT700295	hsa-miR-573	HITS-CLIP	23313552
MIRT700294	hsa-miR-3611	HITS-CLIP	23313552
MIRT700293	hsa-miR-6818-5p	HITS-CLIP	23313552
MIRT700292	hsa-miR-4273	HITS-CLIP	23313552
MIRT700291	hsa-miR-7156-5p	HITS-CLIP	23313552
MIRT700290	hsa-miR-4677-5p	HITS-CLIP	23313552
MIRT700289	hsa-miR-6739-3p	HITS-CLIP	23313552
MIRT641375	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT641374	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT641373	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT641372	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT641371	hsa-miR-4648	HITS-CLIP	23824327
MIRT641370	hsa-miR-1233-5p	HITS-CLIP	23824327
MIRT641369	hsa-miR-6778-5p	HITS-CLIP	23824327
MIRT641368	hsa-miR-4654	HITS-CLIP	23824327
MIRT641367	hsa-miR-4769-5p	HITS-CLIP	23824327
MIRT641366	hsa-miR-4265	HITS-CLIP	23824327
MIRT641365	hsa-miR-4296	HITS-CLIP	23824327
MIRT641364	hsa-miR-4322	HITS-CLIP	23824327
MIRT641363	hsa-miR-6796-5p	HITS-CLIP	23824327
MIRT641362	hsa-miR-6759-5p	HITS-CLIP	23824327
MIRT641361	hsa-miR-2113	HITS-CLIP	23824327
MIRT641360	hsa-miR-5010-3p	HITS-CLIP	23824327
MIRT641375	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT641374	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT641373	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT641372	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT641371	hsa-miR-4648	HITS-CLIP	23824327
MIRT641370	hsa-miR-1233-5p	HITS-CLIP	23824327
MIRT641369	hsa-miR-6778-5p	HITS-CLIP	23824327
MIRT641368	hsa-miR-4654	HITS-CLIP	23824327
MIRT641367	hsa-miR-4769-5p	HITS-CLIP	23824327
MIRT641366	hsa-miR-4265	HITS-CLIP	23824327
MIRT641365	hsa-miR-4296	HITS-CLIP	23824327
MIRT641364	hsa-miR-4322	HITS-CLIP	23824327
MIRT641363	hsa-miR-6796-5p	HITS-CLIP	23824327
MIRT641362	hsa-miR-6759-5p	HITS-CLIP	23824327
MIRT641361	hsa-miR-2113	HITS-CLIP	23824327
MIRT641360	hsa-miR-5010-3p	HITS-CLIP	23824327
MIRT321066	hsa-miR-4282	PAR-CLIP	20371350
MIRT321067	hsa-miR-3646	PAR-CLIP	20371350
MIRT574155	hsa-miR-1252-3p	PAR-CLIP	20371350
MIRT321069	hsa-miR-4731-3p	PAR-CLIP	20371350
MIRT321070	hsa-miR-4801	PAR-CLIP	20371350
MIRT574154	hsa-miR-4742-3p	PAR-CLIP	20371350
MIRT574153	hsa-miR-4524a-3p	PAR-CLIP	20371350
MIRT574152	hsa-miR-8064	PAR-CLIP	20371350
MIRT574151	hsa-miR-3672	PAR-CLIP	20371350
MIRT574150	hsa-miR-6864-3p	PAR-CLIP	20371350
MIRT321064	hsa-miR-507	PAR-CLIP	20371350
MIRT321065	hsa-miR-557	PAR-CLIP	20371350
MIRT571339	hsa-miR-3154	PAR-CLIP	20371350
MIRT571338	hsa-miR-181a-2-3p	PAR-CLIP	20371350
MIRT571337	hsa-miR-1273g-3p	PAR-CLIP	20371350
MIRT571336	hsa-miR-6509-3p	PAR-CLIP	20371350
MIRT571335	hsa-miR-4436b-5p	PAR-CLIP	20371350
MIRT571339	hsa-miR-3154	PAR-CLIP	20371350
MIRT571338	hsa-miR-181a-2-3p	PAR-CLIP	20371350
MIRT571337	hsa-miR-1273g-3p	PAR-CLIP	20371350
MIRT571336	hsa-miR-6509-3p	PAR-CLIP	20371350
MIRT571335	hsa-miR-4436b-5p	PAR-CLIP	20371350
MIRT450378	hsa-miR-590-3p	PAR-CLIP	22100165
MIRT450377	hsa-miR-6512-5p	PAR-CLIP	22100165
MIRT450376	hsa-miR-4635	PAR-CLIP	22100165
MIRT450375	hsa-miR-4775	PAR-CLIP	22100165
MIRT450374	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT450373	hsa-miR-1263	PAR-CLIP	22100165
MIRT450372	hsa-miR-578	PAR-CLIP	22100165
MIRT700311	hsa-miR-6508-5p	HITS-CLIP	23313552
MIRT700310	hsa-miR-8067	HITS-CLIP	23313552
MIRT700309	hsa-miR-4795-5p	HITS-CLIP	23313552
MIRT700308	hsa-miR-5687	HITS-CLIP	23313552
MIRT700307	hsa-miR-518d-5p	HITS-CLIP	23313552
MIRT700306	hsa-miR-518e-5p	HITS-CLIP	23313552
MIRT700305	hsa-miR-518f-5p	HITS-CLIP	23313552
MIRT700304	hsa-miR-519a-5p	HITS-CLIP	23313552
MIRT700303	hsa-miR-519b-5p	HITS-CLIP	23313552
MIRT700302	hsa-miR-519c-5p	HITS-CLIP	23313552
MIRT700301	hsa-miR-520c-5p	HITS-CLIP	23313552
MIRT700300	hsa-miR-522-5p	HITS-CLIP	23313552
MIRT700299	hsa-miR-523-5p	HITS-CLIP	23313552
MIRT700298	hsa-miR-526a	HITS-CLIP	23313552
MIRT700297	hsa-miR-4777-5p	HITS-CLIP	23313552
MIRT700296	hsa-miR-3616-5p	HITS-CLIP	23313552
MIRT700295	hsa-miR-573	HITS-CLIP	23313552
MIRT700294	hsa-miR-3611	HITS-CLIP	23313552
MIRT700293	hsa-miR-6818-5p	HITS-CLIP	23313552
MIRT700292	hsa-miR-4273	HITS-CLIP	23313552
MIRT700291	hsa-miR-7156-5p	HITS-CLIP	23313552
MIRT700290	hsa-miR-4677-5p	HITS-CLIP	23313552
MIRT700289	hsa-miR-6739-3p	HITS-CLIP	23313552
MIRT641375	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT641374	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT641373	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT641372	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT641371	hsa-miR-4648	HITS-CLIP	23824327
MIRT641370	hsa-miR-1233-5p	HITS-CLIP	23824327
MIRT641369	hsa-miR-6778-5p	HITS-CLIP	23824327
MIRT641368	hsa-miR-4654	HITS-CLIP	23824327
MIRT641367	hsa-miR-4769-5p	HITS-CLIP	23824327
MIRT641366	hsa-miR-4265	HITS-CLIP	23824327
MIRT641365	hsa-miR-4296	HITS-CLIP	23824327
MIRT641364	hsa-miR-4322	HITS-CLIP	23824327
MIRT641363	hsa-miR-6796-5p	HITS-CLIP	23824327
MIRT641362	hsa-miR-6759-5p	HITS-CLIP	23824327
MIRT641361	hsa-miR-2113	HITS-CLIP	23824327
MIRT641360	hsa-miR-5010-3p	HITS-CLIP	23824327
MIRT641375	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT641374	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT641373	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT641372	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT641371	hsa-miR-4648	HITS-CLIP	23824327
MIRT641370	hsa-miR-1233-5p	HITS-CLIP	23824327
MIRT641369	hsa-miR-6778-5p	HITS-CLIP	23824327
MIRT641368	hsa-miR-4654	HITS-CLIP	23824327
MIRT641367	hsa-miR-4769-5p	HITS-CLIP	23824327
MIRT641366	hsa-miR-4265	HITS-CLIP	23824327
MIRT641365	hsa-miR-4296	HITS-CLIP	23824327
MIRT641364	hsa-miR-4322	HITS-CLIP	23824327
MIRT641363	hsa-miR-6796-5p	HITS-CLIP	23824327
MIRT641362	hsa-miR-6759-5p	HITS-CLIP	23824327
MIRT641361	hsa-miR-2113	HITS-CLIP	23824327
MIRT641360	hsa-miR-5010-3p	HITS-CLIP	23824327
MIRT321066	hsa-miR-4282	PAR-CLIP	20371350
MIRT321067	hsa-miR-3646	PAR-CLIP	20371350
MIRT574155	hsa-miR-1252-3p	PAR-CLIP	20371350
MIRT321069	hsa-miR-4731-3p	PAR-CLIP	20371350
MIRT321070	hsa-miR-4801	PAR-CLIP	20371350
MIRT574154	hsa-miR-4742-3p	PAR-CLIP	20371350
MIRT574153	hsa-miR-4524a-3p	PAR-CLIP	20371350
MIRT574152	hsa-miR-8064	PAR-CLIP	20371350
MIRT574151	hsa-miR-3672	PAR-CLIP	20371350
MIRT574150	hsa-miR-6864-3p	PAR-CLIP	20371350
MIRT321064	hsa-miR-507	PAR-CLIP	20371350
MIRT321065	hsa-miR-557	PAR-CLIP	20371350
MIRT571339	hsa-miR-3154	PAR-CLIP	20371350
MIRT571338	hsa-miR-181a-2-3p	PAR-CLIP	20371350
MIRT571337	hsa-miR-1273g-3p	PAR-CLIP	20371350
MIRT571336	hsa-miR-6509-3p	PAR-CLIP	20371350
MIRT571335	hsa-miR-4436b-5p	PAR-CLIP	20371350
MIRT571339	hsa-miR-3154	PAR-CLIP	20371350
MIRT571338	hsa-miR-181a-2-3p	PAR-CLIP	20371350
MIRT571337	hsa-miR-1273g-3p	PAR-CLIP	20371350
MIRT571336	hsa-miR-6509-3p	PAR-CLIP	20371350
MIRT571335	hsa-miR-4436b-5p	PAR-CLIP	20371350
MIRT450378	hsa-miR-590-3p	PAR-CLIP	22100165
MIRT450377	hsa-miR-6512-5p	PAR-CLIP	22100165
MIRT450376	hsa-miR-4635	PAR-CLIP	22100165
MIRT450375	hsa-miR-4775	PAR-CLIP	22100165
MIRT450374	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT450373	hsa-miR-1263	PAR-CLIP	22100165
MIRT450372	hsa-miR-578	PAR-CLIP	22100165
MIRT1286435	hsa-miR-1251	CLIP-seq
MIRT1286436	hsa-miR-148a	CLIP-seq
MIRT1286437	hsa-miR-148b	CLIP-seq
MIRT1286438	hsa-miR-152	CLIP-seq
MIRT1286439	hsa-miR-154	CLIP-seq
MIRT1286440	hsa-miR-181a	CLIP-seq
MIRT1286441	hsa-miR-181b	CLIP-seq
MIRT1286442	hsa-miR-181c	CLIP-seq
MIRT1286443	hsa-miR-181d	CLIP-seq
MIRT1286444	hsa-miR-190	CLIP-seq
MIRT1286445	hsa-miR-190b	CLIP-seq
MIRT1286446	hsa-miR-208a	CLIP-seq
MIRT1286447	hsa-miR-208b	CLIP-seq
MIRT1286448	hsa-miR-2115	CLIP-seq
MIRT1286449	hsa-miR-27a	CLIP-seq
MIRT1286450	hsa-miR-27b	CLIP-seq
MIRT1286451	hsa-miR-3123	CLIP-seq
MIRT1286452	hsa-miR-3143	CLIP-seq
MIRT1286453	hsa-miR-3163	CLIP-seq
MIRT1286454	hsa-miR-3177-5p	CLIP-seq
MIRT1286455	hsa-miR-3185	CLIP-seq
MIRT1286456	hsa-miR-3659	CLIP-seq
MIRT1286457	hsa-miR-3662	CLIP-seq
MIRT1286458	hsa-miR-4262	CLIP-seq
MIRT1286459	hsa-miR-4276	CLIP-seq
MIRT1286460	hsa-miR-4280	CLIP-seq
MIRT1286461	hsa-miR-4420	CLIP-seq
MIRT1286462	hsa-miR-4421	CLIP-seq
MIRT1286463	hsa-miR-4658	CLIP-seq
MIRT1286464	hsa-miR-4659a-5p	CLIP-seq
MIRT1286465	hsa-miR-4659b-5p	CLIP-seq
MIRT1286466	hsa-miR-4728-3p	CLIP-seq
MIRT1286467	hsa-miR-4729	CLIP-seq
MIRT1286468	hsa-miR-4733-5p	CLIP-seq
MIRT1286469	hsa-miR-4747-5p	CLIP-seq
MIRT1286470	hsa-miR-4758-5p	CLIP-seq
MIRT1286471	hsa-miR-4781-5p	CLIP-seq
MIRT1286472	hsa-miR-4790-3p	CLIP-seq
MIRT1286473	hsa-miR-4797-5p	CLIP-seq
MIRT1286474	hsa-miR-4803	CLIP-seq
MIRT1286475	hsa-miR-495	CLIP-seq
MIRT1286476	hsa-miR-499-5p	CLIP-seq
MIRT1286477	hsa-miR-5096	CLIP-seq
MIRT1286478	hsa-miR-513a-5p	CLIP-seq
MIRT1286479	hsa-miR-516a-3p	CLIP-seq
MIRT1286480	hsa-miR-574-5p	CLIP-seq
MIRT1286481	hsa-miR-576-3p	CLIP-seq
MIRT1286482	hsa-miR-592	CLIP-seq
MIRT1286483	hsa-miR-597	CLIP-seq
MIRT1286484	hsa-miR-628-5p	CLIP-seq
MIRT1286485	hsa-miR-633	CLIP-seq
MIRT1286486	hsa-miR-642b	CLIP-seq
MIRT1286487	hsa-miR-668	CLIP-seq
MIRT1286488	hsa-miR-7	CLIP-seq
MIRT1286489	hsa-miR-759	CLIP-seq
MIRT1286490	hsa-miR-892a	CLIP-seq
MIRT2084909	hsa-miR-1179	CLIP-seq
MIRT2084910	hsa-miR-1193	CLIP-seq
MIRT2084911	hsa-miR-1207-5p	CLIP-seq
MIRT2084912	hsa-miR-1246	CLIP-seq
MIRT2084913	hsa-miR-1257	CLIP-seq
MIRT2084914	hsa-miR-128	CLIP-seq
MIRT2084915	hsa-miR-140-3p	CLIP-seq
MIRT2084916	hsa-miR-193a-3p	CLIP-seq
MIRT2084917	hsa-miR-193b	CLIP-seq
MIRT2084918	hsa-miR-3125	CLIP-seq
MIRT1286453	hsa-miR-3163	CLIP-seq
MIRT2084919	hsa-miR-3201	CLIP-seq
MIRT2084920	hsa-miR-342-5p	CLIP-seq
MIRT2084921	hsa-miR-3674	CLIP-seq
MIRT2084922	hsa-miR-3916	CLIP-seq
MIRT2084923	hsa-miR-4496	CLIP-seq
MIRT2084924	hsa-miR-4664-5p	CLIP-seq
MIRT2084925	hsa-miR-4699-3p	CLIP-seq
MIRT2084926	hsa-miR-4736	CLIP-seq
MIRT2084927	hsa-miR-4763-3p	CLIP-seq
MIRT1286471	hsa-miR-4781-5p	CLIP-seq
MIRT2084928	hsa-miR-4787-5p	CLIP-seq
MIRT2084929	hsa-miR-4791	CLIP-seq
MIRT2084930	hsa-miR-543	CLIP-seq
MIRT2084931	hsa-miR-548aa	CLIP-seq
MIRT2084932	hsa-miR-579	CLIP-seq
MIRT2084933	hsa-miR-664	CLIP-seq
MIRT1286488	hsa-miR-7	CLIP-seq
MIRT2084934	hsa-miR-892b	CLIP-seq
MIRT2084935	hsa-miR-944	CLIP-seq
MIRT2310398	hsa-miR-1207-3p	CLIP-seq
MIRT2310399	hsa-miR-1229	CLIP-seq
MIRT2310400	hsa-miR-1237	CLIP-seq
MIRT2084913	hsa-miR-1257	CLIP-seq
MIRT1286439	hsa-miR-154	CLIP-seq
MIRT1286444	hsa-miR-190	CLIP-seq
MIRT1286445	hsa-miR-190b	CLIP-seq
MIRT2310401	hsa-miR-2116	CLIP-seq
MIRT2310402	hsa-miR-22	CLIP-seq
MIRT2084918	hsa-miR-3125	CLIP-seq
MIRT2310403	hsa-miR-3148	CLIP-seq
MIRT1286453	hsa-miR-3163	CLIP-seq
MIRT2310404	hsa-miR-3182	CLIP-seq
MIRT2310405	hsa-miR-345	CLIP-seq
MIRT2310406	hsa-miR-3653	CLIP-seq
MIRT1286456	hsa-miR-3659	CLIP-seq
MIRT2084922	hsa-miR-3916	CLIP-seq
MIRT2310407	hsa-miR-3936	CLIP-seq
MIRT1286460	hsa-miR-4280	CLIP-seq
MIRT2310408	hsa-miR-4453	CLIP-seq
MIRT2084923	hsa-miR-4496	CLIP-seq
MIRT2310409	hsa-miR-4517	CLIP-seq
MIRT2310410	hsa-miR-4538	CLIP-seq
MIRT1286463	hsa-miR-4658	CLIP-seq
MIRT2084925	hsa-miR-4699-3p	CLIP-seq
MIRT1286470	hsa-miR-4758-5p	CLIP-seq
MIRT1286480	hsa-miR-574-5p	CLIP-seq
MIRT2310411	hsa-miR-589	CLIP-seq
MIRT2084910	hsa-miR-1193	CLIP-seq
MIRT2084911	hsa-miR-1207-5p	CLIP-seq
MIRT2606757	hsa-miR-122	CLIP-seq
MIRT2606758	hsa-miR-1228	CLIP-seq
MIRT2310399	hsa-miR-1229	CLIP-seq
MIRT2084912	hsa-miR-1246	CLIP-seq
MIRT2606759	hsa-miR-1256	CLIP-seq
MIRT2606760	hsa-miR-1266	CLIP-seq
MIRT2606761	hsa-miR-1302	CLIP-seq
MIRT1286439	hsa-miR-154	CLIP-seq
MIRT2606762	hsa-miR-1587	CLIP-seq
MIRT1286440	hsa-miR-181a	CLIP-seq
MIRT1286441	hsa-miR-181b	CLIP-seq
MIRT1286442	hsa-miR-181c	CLIP-seq
MIRT1286443	hsa-miR-181d	CLIP-seq
MIRT2606763	hsa-miR-1972	CLIP-seq
MIRT2606764	hsa-miR-203	CLIP-seq
MIRT2606765	hsa-miR-2114	CLIP-seq
MIRT2310401	hsa-miR-2116	CLIP-seq
MIRT2606766	hsa-miR-2276	CLIP-seq
MIRT2606767	hsa-miR-2681	CLIP-seq
MIRT2606768	hsa-miR-296-5p	CLIP-seq
MIRT2606769	hsa-miR-3065-5p	CLIP-seq
MIRT2084918	hsa-miR-3125	CLIP-seq
MIRT2606770	hsa-miR-3140-5p	CLIP-seq
MIRT2606771	hsa-miR-3144-3p	CLIP-seq
MIRT2310403	hsa-miR-3148	CLIP-seq
MIRT1286453	hsa-miR-3163	CLIP-seq
MIRT2606772	hsa-miR-3190	CLIP-seq
MIRT2606773	hsa-miR-3194-3p	CLIP-seq
MIRT2084919	hsa-miR-3201	CLIP-seq
MIRT2606774	hsa-miR-34b	CLIP-seq
MIRT2606775	hsa-miR-3591-5p	CLIP-seq
MIRT2606776	hsa-miR-3614-5p	CLIP-seq
MIRT2606777	hsa-miR-3620	CLIP-seq
MIRT2606778	hsa-miR-3647-3p	CLIP-seq
MIRT2310406	hsa-miR-3653	CLIP-seq
MIRT2606779	hsa-miR-3658	CLIP-seq
MIRT1286456	hsa-miR-3659	CLIP-seq
MIRT1286457	hsa-miR-3662	CLIP-seq
MIRT2606780	hsa-miR-3664-3p	CLIP-seq
MIRT2606781	hsa-miR-3671	CLIP-seq
MIRT2606782	hsa-miR-376c	CLIP-seq
MIRT2606783	hsa-miR-380	CLIP-seq
MIRT2606784	hsa-miR-3907	CLIP-seq
MIRT2084922	hsa-miR-3916	CLIP-seq
MIRT2310407	hsa-miR-3936	CLIP-seq
MIRT1286458	hsa-miR-4262	CLIP-seq
MIRT1286460	hsa-miR-4280	CLIP-seq
MIRT2606785	hsa-miR-4298	CLIP-seq
MIRT2606786	hsa-miR-4318	CLIP-seq
MIRT2606787	hsa-miR-4426	CLIP-seq
MIRT2606788	hsa-miR-4437	CLIP-seq
MIRT2606789	hsa-miR-4460	CLIP-seq
MIRT2606790	hsa-miR-4461	CLIP-seq
MIRT2606791	hsa-miR-4476	CLIP-seq
MIRT2606792	hsa-miR-4484	CLIP-seq
MIRT2606793	hsa-miR-4495	CLIP-seq
MIRT2084923	hsa-miR-4496	CLIP-seq
MIRT2606794	hsa-miR-4509	CLIP-seq
MIRT2310409	hsa-miR-4517	CLIP-seq
MIRT2606795	hsa-miR-4518	CLIP-seq
MIRT2606796	hsa-miR-4534	CLIP-seq
MIRT2606797	hsa-miR-4647	CLIP-seq
MIRT2606798	hsa-miR-4650-5p	CLIP-seq
MIRT1286463	hsa-miR-4658	CLIP-seq
MIRT2606799	hsa-miR-4662b	CLIP-seq
MIRT2606800	hsa-miR-4668-3p	CLIP-seq
MIRT2606801	hsa-miR-4668-5p	CLIP-seq
MIRT2606802	hsa-miR-4674	CLIP-seq
MIRT2606803	hsa-miR-4699-5p	CLIP-seq
MIRT2606804	hsa-miR-4717-5p	CLIP-seq
MIRT2606805	hsa-miR-4720-5p	CLIP-seq
MIRT2606806	hsa-miR-4726-3p	CLIP-seq
MIRT2606807	hsa-miR-4727-3p	CLIP-seq
MIRT1286467	hsa-miR-4729	CLIP-seq
MIRT1286468	hsa-miR-4733-5p	CLIP-seq
MIRT2084926	hsa-miR-4736	CLIP-seq
MIRT2606808	hsa-miR-4740-3p	CLIP-seq
MIRT2606809	hsa-miR-4758-3p	CLIP-seq
MIRT1286470	hsa-miR-4758-5p	CLIP-seq
MIRT2084927	hsa-miR-4763-3p	CLIP-seq
MIRT2606810	hsa-miR-4772-3p	CLIP-seq
MIRT2084929	hsa-miR-4791	CLIP-seq
MIRT2606811	hsa-miR-4799-3p	CLIP-seq
MIRT2606812	hsa-miR-4802-5p	CLIP-seq
MIRT2606813	hsa-miR-490-5p	CLIP-seq
MIRT1286475	hsa-miR-495	CLIP-seq
MIRT2606814	hsa-miR-513a-3p	CLIP-seq
MIRT2606815	hsa-miR-516a-5p	CLIP-seq
MIRT2606816	hsa-miR-522	CLIP-seq
MIRT2084930	hsa-miR-543	CLIP-seq
MIRT2606817	hsa-miR-548an	CLIP-seq
MIRT2606818	hsa-miR-548g	CLIP-seq
MIRT2606819	hsa-miR-570	CLIP-seq
MIRT1286480	hsa-miR-574-5p	CLIP-seq
MIRT1286481	hsa-miR-576-3p	CLIP-seq
MIRT1286482	hsa-miR-592	CLIP-seq
MIRT1286483	hsa-miR-597	CLIP-seq
MIRT1286485	hsa-miR-633	CLIP-seq
MIRT2606820	hsa-miR-635	CLIP-seq
MIRT1286486	hsa-miR-642b	CLIP-seq
MIRT2606821	hsa-miR-663b	CLIP-seq
MIRT1286488	hsa-miR-7	CLIP-seq
MIRT2606822	hsa-miR-888	CLIP-seq
MIRT2084935	hsa-miR-944	CLIP-seq
MIRT2084910	hsa-miR-1193	CLIP-seq
MIRT2084911	hsa-miR-1207-5p	CLIP-seq
MIRT2606757	hsa-miR-122	CLIP-seq
MIRT2606758	hsa-miR-1228	CLIP-seq
MIRT2084912	hsa-miR-1246	CLIP-seq
MIRT2606760	hsa-miR-1266	CLIP-seq
MIRT2606761	hsa-miR-1302	CLIP-seq
MIRT1286439	hsa-miR-154	CLIP-seq
MIRT1286440	hsa-miR-181a	CLIP-seq
MIRT1286441	hsa-miR-181b	CLIP-seq
MIRT1286442	hsa-miR-181c	CLIP-seq
MIRT1286443	hsa-miR-181d	CLIP-seq
MIRT2606763	hsa-miR-1972	CLIP-seq
MIRT2606765	hsa-miR-2114	CLIP-seq
MIRT2310401	hsa-miR-2116	CLIP-seq
MIRT2606767	hsa-miR-2681	CLIP-seq
MIRT2606768	hsa-miR-296-5p	CLIP-seq
MIRT2606769	hsa-miR-3065-5p	CLIP-seq
MIRT2084918	hsa-miR-3125	CLIP-seq
MIRT2606771	hsa-miR-3144-3p	CLIP-seq
MIRT2310403	hsa-miR-3148	CLIP-seq
MIRT1286453	hsa-miR-3163	CLIP-seq
MIRT2084919	hsa-miR-3201	CLIP-seq
MIRT2606774	hsa-miR-34b	CLIP-seq
MIRT2606775	hsa-miR-3591-5p	CLIP-seq
MIRT2606776	hsa-miR-3614-5p	CLIP-seq
MIRT2606777	hsa-miR-3620	CLIP-seq
MIRT2606778	hsa-miR-3647-3p	CLIP-seq
MIRT2310406	hsa-miR-3653	CLIP-seq
MIRT2606779	hsa-miR-3658	CLIP-seq
MIRT1286456	hsa-miR-3659	CLIP-seq
MIRT1286457	hsa-miR-3662	CLIP-seq
MIRT2606780	hsa-miR-3664-3p	CLIP-seq
MIRT2606781	hsa-miR-3671	CLIP-seq
MIRT2606782	hsa-miR-376c	CLIP-seq
MIRT2606783	hsa-miR-380	CLIP-seq
MIRT2606784	hsa-miR-3907	CLIP-seq
MIRT2084922	hsa-miR-3916	CLIP-seq
MIRT2310407	hsa-miR-3936	CLIP-seq
MIRT1286458	hsa-miR-4262	CLIP-seq
MIRT1286460	hsa-miR-4280	CLIP-seq
MIRT2606785	hsa-miR-4298	CLIP-seq
MIRT2606787	hsa-miR-4426	CLIP-seq
MIRT2606789	hsa-miR-4460	CLIP-seq
MIRT2606790	hsa-miR-4461	CLIP-seq
MIRT2606793	hsa-miR-4495	CLIP-seq
MIRT2084923	hsa-miR-4496	CLIP-seq
MIRT2310409	hsa-miR-4517	CLIP-seq
MIRT2606795	hsa-miR-4518	CLIP-seq
MIRT2606796	hsa-miR-4534	CLIP-seq
MIRT2606797	hsa-miR-4647	CLIP-seq
MIRT2606798	hsa-miR-4650-5p	CLIP-seq
MIRT1286463	hsa-miR-4658	CLIP-seq
MIRT2606799	hsa-miR-4662b	CLIP-seq
MIRT2606800	hsa-miR-4668-3p	CLIP-seq
MIRT2606801	hsa-miR-4668-5p	CLIP-seq
MIRT2606804	hsa-miR-4717-5p	CLIP-seq
MIRT2606806	hsa-miR-4726-3p	CLIP-seq
MIRT2606807	hsa-miR-4727-3p	CLIP-seq
MIRT1286467	hsa-miR-4729	CLIP-seq
MIRT1286468	hsa-miR-4733-5p	CLIP-seq
MIRT2084926	hsa-miR-4736	CLIP-seq
MIRT2606808	hsa-miR-4740-3p	CLIP-seq
MIRT2606809	hsa-miR-4758-3p	CLIP-seq
MIRT1286470	hsa-miR-4758-5p	CLIP-seq
MIRT2084927	hsa-miR-4763-3p	CLIP-seq
MIRT2084929	hsa-miR-4791	CLIP-seq
MIRT2606812	hsa-miR-4802-5p	CLIP-seq
MIRT2606813	hsa-miR-490-5p	CLIP-seq
MIRT1286475	hsa-miR-495	CLIP-seq
MIRT2606814	hsa-miR-513a-3p	CLIP-seq
MIRT2606815	hsa-miR-516a-5p	CLIP-seq
MIRT2606816	hsa-miR-522	CLIP-seq
MIRT2084930	hsa-miR-543	CLIP-seq
MIRT1286480	hsa-miR-574-5p	CLIP-seq
MIRT1286481	hsa-miR-576-3p	CLIP-seq
MIRT1286482	hsa-miR-592	CLIP-seq
MIRT1286483	hsa-miR-597	CLIP-seq
MIRT1286485	hsa-miR-633	CLIP-seq
MIRT2606820	hsa-miR-635	CLIP-seq
MIRT1286486	hsa-miR-642b	CLIP-seq
MIRT2606821	hsa-miR-663b	CLIP-seq

Show/Hide all(48)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002686	Process	Negative regulation of leukocyte migration	IEA
GO:0003677	Function	DNA binding	IEA
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IBA
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IDA	11452015, 20937701
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IEA
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IMP	23382462
GO:0005515	Function	Protein binding	IPI	16189514, 16499958, 17450153, 25416956, 28514442, 32296183, 32814053, 33961781, 35271311
GO:0005730	Component	Nucleolus	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005768	Component	Endosome	IEA
GO:0005769	Component	Early endosome	IEA
GO:0005769	Component	Early endosome	IMP	23382462
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0006612	Process	Protein targeting to membrane	IMP	23382462
GO:0006897	Process	Endocytosis	IEA
GO:0006898	Process	Receptor-mediated endocytosis	IEA
GO:0007265	Process	Ras protein signal transduction	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0015031	Process	Protein transport	IEA
GO:0016192	Process	Vesicle-mediated transport	IEA
GO:0016197	Process	Endosomal transport	IDA	11452015
GO:0030139	Component	Endocytic vesicle	IBA
GO:0030425	Component	Dendrite	IEA
GO:0031267	Function	Small GTPase binding	IBA
GO:0031267	Function	Small GTPase binding	IPI	23382462
GO:0031901	Component	Early endosome membrane	IDA	11452015
GO:0031901	Component	Early endosome membrane	TAS
GO:0031982	Component	Vesicle	IEA
GO:0032715	Process	Negative regulation of interleukin-6 production	IEA
GO:0032764	Process	Negative regulation of mast cell cytokine production	IEA
GO:0033004	Process	Negative regulation of mast cell activation	IEA
GO:0038109	Process	Kit signaling pathway	IEA
GO:0043303	Process	Mast cell degranulation	IEA
GO:0043305	Process	Negative regulation of mast cell degranulation	IEA
GO:0046580	Process	Negative regulation of Ras protein signal transduction	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0048261	Process	Negative regulation of receptor-mediated endocytosis	IEA
GO:0050728	Process	Negative regulation of inflammatory response	IEA
GO:0051649	Process	Establishment of localization in cell	IEA
GO:0055037	Component	Recycling endosome	IEA
GO:0060368	Process	Regulation of Fc receptor mediated stimulatory signaling pathway	IEA
GO:0061630	Function	Ubiquitin protein ligase activity	IEA
GO:0097531	Process	Mast cell migration	IEA
GO:0098830	Component	Presynaptic endosome	IEA
GO:0098935	Process	Dendritic transport	IEA
GO:1900235	Process	Negative regulation of Kit signaling pathway	IEA

MIM	HGNC	e!Ensembl
609700	17676	ENSG00000154710

Protein

UniProt ID

Q9UJ41

Protein name

Rab5 GDP/GTP exchange factor (RAP1) (Rabaptin-5-associated exchange factor for Rab5) (Rabex-5)

Protein function

Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase (By simila

PDB

1TXU , 2C7M , 2C7N , 2OT3 , 4N3X , 4N3Y , 4N3Z , 4Q9U

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01754	zf-A20	17 → 40	A20-like zinc finger	Family
PF18151	DUF5601	158 → 220	Domain of unknown function (DUF5601)	Domain
PF02204	VPS9	268 → 371	Vacuolar sorting protein 9 (VPS9) domain	Family

Sequence

MSLKSERRGIHVDQSDLLCKKGCGYYGNPAWQGFCSKCWREEYHKARQKQIQEDWELAER
LQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTTVKKFFSASSRVGSKKEIQEA
KAPSPSINRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQTKLFLEGMHYKRDLSIEEQSE
CAQDFYHNVAERMQTRGKVPPERVEKIMDQIEKYIMTRLYKYVFCPETTDDEKKDLAIQK
RIRALRWVTPQMLCVPVNEDIPEVSDMVVKAITDIIEMDSKRVPRDKLACITKCSKHIFN
AIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLC
CAVAFIEKLDAQSLNLSQEDFDRYMSGQTSPRKQEAESWSPDACLGVKQMYKNLDLLSQL
NERQERIMNEAKKLEKDLIDWTDGIAREVQDIVEKYPLEIKPPNQPLAAIDSENVENDKL
PPPLQPQVYAG

Sequence length

491

Interactions

View interactions

	KEGG		Reactome
	Mitophagy - animal		TBC/RABGAPs RAB GEFs exchange GTP for GDP on RABs

Show/Hide Unknown Diseases (2)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Alzheimer disease	Alzheimer's disease or family history of Alzheimer's disease	N/A	N/A	GWAS
Ischemic Stroke	Ischemic stroke	N/A	N/A	GWAS

Show/Hide Text Mining Associations (9)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenocarcinoma of Lung	Associate	37682707
Carcinoma Non Small Cell Lung	Associate	35836137
Colorectal Neoplasms	Associate	24716822, 28617553
Inflammatory Bowel Diseases	Associate	24155895
Leukemia Lymphocytic Chronic B Cell	Associate	14615375
Lymphatic Metastasis	Stimulate	24716822
Neoplasms	Associate	16224153, 24716822, 26002576
Prostatic Neoplasms	Stimulate	24716822
Small Cell Lung Carcinoma	Associate	26002576

RABGEF1 (RAB guanine nucleotide exchange factor 1)