ZNF638 (zinc finger protein 638)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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27332 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Zinc finger protein 638 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ZNF638 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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NP220, ZFML, Zfp638 |
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Chromosome
Chromosome number
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2 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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2p13.2 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is a nucleoplasmic protein. It binds cytidine-rich sequences in double-stranded DNA. This protein has three types of domains: MH1, MH2 (repeated three times) and MH3. It is associated with packaging, transferring, or proce |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||
| UniProt ID | Q14966 | |||||||||||||||
| Protein name | Zinc finger protein 638 (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL-associated antigen se33-1) (Nuclear protein 220) (Zinc finger matrin-like protein) | |||||||||||||||
| Protein function | Transcription factor that binds to cytidine clusters in double-stranded DNA (PubMed:30487602, PubMed:8647861). Plays a key role in the silencing of unintegrated retroviral DNA: some part of the retroviral DNA formed immediately after infection r | |||||||||||||||
| PDB | 6SXW | |||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 1978 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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