GLDC (glycine decarboxylase)

Gene

• Entrez ID: 2731
• Gene name: Glycine decarboxylase
• Gene symbol: GLDC
• Synonyms (NCBI Gene): GCE, GCE1, GCSP, HYGN1
• Chromosome: 9
• Chromosome location: 9p24.1
• Summary: Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs121964974	C>A	Pathogenic	Coding sequence variant, missense variant
rs121964975	AAG>-	Pathogenic-likely-pathogenic	Coding sequence variant, inframe deletion
rs121964976	C>G,T	Pathogenic, benign	Coding sequence variant, synonymous variant, missense variant
rs121964977	G>A	Pathogenic	Coding sequence variant, missense variant
rs121964978	A>G	Pathogenic	Initiator codon variant, missense variant
rs121964979	G>A,T	Likely-pathogenic, pathogenic	Coding sequence variant, missense variant
rs121964980	C>T	Likely-pathogenic	Coding sequence variant, missense variant
rs140877566	G>A,C	Conflicting-interpretations-of-pathogenicity, likely-benign	Intron variant
rs144090917	C>G,T	Conflicting-interpretations-of-pathogenicity, benign	Missense variant, coding sequence variant
rs149070244	C>G,T	Pathogenic-likely-pathogenic, pathogenic	Splice donor variant
rs150171524	G>A,C	Conflicting-interpretations-of-pathogenicity, pathogenic	Missense variant, coding sequence variant
rs151163582	C>A	Likely-pathogenic	Missense variant, coding sequence variant
rs151268759	C>A,G,T	Likely-pathogenic, conflicting-interpretations-of-pathogenicity	Missense variant, coding sequence variant
rs188269735	A>C	Pathogenic	Missense variant, coding sequence variant
rs191905539	C>A	Pathogenic	Coding sequence variant, stop gained
rs201135624	G>A	Uncertain-significance, pathogenic	Missense variant, coding sequence variant
rs367781728	G>A,C	Likely-benign, conflicting-interpretations-of-pathogenicity	Synonymous variant, coding sequence variant
rs373618804	T>A	Likely-pathogenic	Stop gained, coding sequence variant
rs386833516	->A	Likely-pathogenic	Frameshift variant, coding sequence variant
rs386833517	G>A,C	Pathogenic	Stop gained, missense variant, coding sequence variant
rs386833518	T>-	Pathogenic-likely-pathogenic, pathogenic	Frameshift variant, coding sequence variant
rs386833519	G>A,C	Likely-pathogenic	Missense variant, coding sequence variant
rs386833520	G>-	Likely-pathogenic	Frameshift variant, coding sequence variant
rs386833521	G>A	Pathogenic-likely-pathogenic	Stop gained, coding sequence variant
rs386833522	->TTTG	Likely-pathogenic	Frameshift variant, coding sequence variant
rs386833523	A>G,T	Uncertain-significance, likely-pathogenic	Missense variant, coding sequence variant
rs386833524	C>T	Likely-pathogenic	Missense variant, coding sequence variant
rs386833525	C>G	Likely-pathogenic	Splice acceptor variant
rs386833526	->C	Likely-pathogenic	Frameshift variant, coding sequence variant
rs386833527	G>A,C	Likely-pathogenic	Missense variant, coding sequence variant
rs386833528	T>A	Likely-pathogenic	Missense variant, coding sequence variant
rs386833529	T>C	Pathogenic	Missense variant, coding sequence variant
rs386833530	C>G,T	Uncertain-significance, likely-pathogenic	Missense variant, coding sequence variant
rs386833531	G>A	Pathogenic-likely-pathogenic	Stop gained, coding sequence variant
rs386833532	GTCATAACCTG>-	Likely-pathogenic	Frameshift variant, coding sequence variant
rs386833533	A>C	Likely-pathogenic	Missense variant, coding sequence variant
rs386833534	C>T	Likely-pathogenic	Splice donor variant
rs386833535	C>A,T	Uncertain-significance, likely-pathogenic	Missense variant, coding sequence variant
rs386833536	T>C	Likely-pathogenic	Missense variant, coding sequence variant
rs386833537	G>A	Likely-pathogenic	Stop gained, coding sequence variant
rs386833538	C>G	Likely-pathogenic	Missense variant, coding sequence variant
rs386833539	G>C	Likely-pathogenic	Missense variant, coding sequence variant
rs386833540	G>A	Likely-pathogenic	Missense variant, coding sequence variant
rs386833541	GAT>TAAACCAGGA	Likely-pathogenic	Stop gained, inframe indel, coding sequence variant
rs386833542	C>G,T	Likely-pathogenic	Missense variant, coding sequence variant
rs386833543	G>-	Pathogenic	Frameshift variant, coding sequence variant
rs386833544	A>T	Likely-pathogenic	Missense variant, coding sequence variant
rs386833545	T>C	Pathogenic	Splice acceptor variant
rs386833546	CA>-	Likely-pathogenic	Frameshift variant, coding sequence variant
rs386833547	T>G	Likely-pathogenic	Missense variant, coding sequence variant
rs386833549	C>G,T	Pathogenic, likely-pathogenic	Missense variant, coding sequence variant
rs386833550	C>T	Pathogenic-likely-pathogenic	Missense variant, coding sequence variant
rs386833551	G>A	Likely-pathogenic	Missense variant, coding sequence variant
rs386833552	G>A	Likely-pathogenic	Missense variant, coding sequence variant
rs386833553	C>T	Pathogenic-likely-pathogenic	Missense variant, coding sequence variant
rs386833554	C>T	Pathogenic	Splice acceptor variant
rs386833555	T>A,C	Likely-pathogenic	Missense variant, coding sequence variant
rs386833556	G>A,C	Conflicting-interpretations-of-pathogenicity	Missense variant, coding sequence variant
rs386833557	C>T	Likely-pathogenic	Stop gained, coding sequence variant
rs386833558	T>-	Likely-pathogenic	Frameshift variant, coding sequence variant
rs386833559	A>C,G	Uncertain-significance, likely-pathogenic	Missense variant, coding sequence variant
rs386833560	G>A	Pathogenic-likely-pathogenic	Missense variant, coding sequence variant
rs386833563	C>T	Likely-pathogenic	Splice donor variant
rs386833564	A>C,G	Likely-pathogenic	Stop gained, synonymous variant, coding sequence variant
rs386833565	G>T	Pathogenic	Synonymous variant, coding sequence variant
rs386833566	T>A	Likely-pathogenic	Missense variant, coding sequence variant
rs386833567	G>A	Likely-pathogenic	Stop gained, coding sequence variant
rs386833568	C>T	Likely-pathogenic	Intron variant
rs386833569	C>G	Likely-pathogenic	Splice acceptor variant
rs386833570	G>A	Likely-pathogenic	Missense variant, coding sequence variant
rs386833571	A>G	Likely-pathogenic	Missense variant, coding sequence variant
rs386833572	->T	Likely-pathogenic	Stop gained, coding sequence variant
rs386833573	T>C	Likely-pathogenic	Missense variant, coding sequence variant
rs386833574	G>-	Likely-pathogenic	Frameshift variant, coding sequence variant
rs386833575	C>G,T	Pathogenic	Splice donor variant
rs386833576	G>A,C,T	Likely-pathogenic	Stop gained, missense variant, coding sequence variant
rs386833577	T>A	Likely-pathogenic	Missense variant, coding sequence variant
rs386833578	T>C,G	Likely-pathogenic	Missense variant, coding sequence variant
rs386833579	C>A	Likely-pathogenic	Stop gained, coding sequence variant
rs386833580	T>C	Likely-pathogenic	Missense variant, coding sequence variant
rs386833581	C>G	Likely-pathogenic	Synonymous variant, coding sequence variant
rs386833582	G>A,C,T	Likely-pathogenic	Missense variant, coding sequence variant
rs386833583	G>A	Likely-pathogenic	Missense variant, coding sequence variant
rs386833584	C>A,T	Likely-pathogenic	Missense variant, coding sequence variant
rs386833585	G>A,C	Likely-pathogenic	Stop gained, missense variant, coding sequence variant
rs386833586	G>-	Pathogenic-likely-pathogenic	Frameshift variant, coding sequence variant
rs386833587	G>A	Pathogenic-likely-pathogenic	Missense variant, coding sequence variant
rs386833588	C>A	Likely-pathogenic	Stop gained, coding sequence variant
rs386833589	C>G	Likely-pathogenic	Missense variant, coding sequence variant
rs386833590	C>A	Likely-pathogenic	Splice donor variant
rs386833591	A>C	Likely-pathogenic	Missense variant, coding sequence variant
rs386833592	C>A,G,T	Likely-pathogenic	Missense variant, coding sequence variant
rs386833593	G>T	Likely-pathogenic	Missense variant, coding sequence variant
rs542056100	C>T	Pathogenic	Splice donor variant
rs570097430	G>A,T	Likely-pathogenic	Stop gained, missense variant, coding sequence variant
rs751025203	G>A	Pathogenic	Coding sequence variant, stop gained
rs751822565	C>A	Pathogenic-likely-pathogenic	Coding sequence variant, missense variant
rs755313904	->GAAC	Pathogenic, likely-pathogenic	Coding sequence variant, frameshift variant
rs759133707	C>T	Pathogenic	Coding sequence variant, missense variant
rs762989914	G>A	Pathogenic	Coding sequence variant, stop gained
rs763517274	C>G,T	Likely-pathogenic	Coding sequence variant, missense variant
rs765906340	C>G,T	Pathogenic	Splice donor variant
rs766762760	GTTT>-	Likely-pathogenic	Coding sequence variant, frameshift variant
rs768091555	C>A	Likely-pathogenic	Intron variant
rs769625871	TGC>-	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, inframe deletion
rs772068893	->AT	Pathogenic-likely-pathogenic	Coding sequence variant, frameshift variant
rs772574530	T>C	Uncertain-significance, likely-pathogenic	Coding sequence variant, missense variant
rs772871471	G>C	Likely-pathogenic	Coding sequence variant, missense variant
rs774099283	C>A,G	Likely-pathogenic	Splice donor variant
rs777365335	C>A,G	Likely-pathogenic	Coding sequence variant, missense variant, stop gained
rs906049409	C>T	Likely-pathogenic	Coding sequence variant, missense variant
rs925908885	C>T	Pathogenic-likely-pathogenic	Missense variant, coding sequence variant
rs978795483	C>A,G	Likely-pathogenic, pathogenic	Splice donor variant
rs1114167353	A>T	Pathogenic	Coding sequence variant, missense variant
rs1163356968	C>G,T	Pathogenic	Coding sequence variant, missense variant, stop gained
rs1183976692	G>A	Likely-pathogenic	Coding sequence variant, missense variant
rs1196401015	ATGATAGC>-	Likely-pathogenic	Coding sequence variant, frameshift variant
rs1207147043	G>A	Likely-pathogenic	Coding sequence variant, missense variant
rs1211616091	C>T	Likely-pathogenic	Splice donor variant
rs1226098656	G>A,T	Likely-pathogenic	Synonymous variant, stop gained, coding sequence variant
rs1251443902	T>-	Pathogenic-likely-pathogenic	Coding sequence variant, frameshift variant
rs1259354298	T>C	Likely-pathogenic	Splice acceptor variant
rs1345599468	A>-	Pathogenic	Frameshift variant, coding sequence variant
rs1368757896	C>G,T	Likely-pathogenic	Splice donor variant
rs1399754800	C>-	Likely-pathogenic	Splice donor variant, coding sequence variant
rs1406713104	C>T	Likely-pathogenic	Coding sequence variant, missense variant
rs1429861000	C>T	Likely-pathogenic	Splice acceptor variant
rs1430968530	T>A	Pathogenic-likely-pathogenic	Stop gained, coding sequence variant
rs1477860542	C>A,T	Likely-pathogenic	Missense variant, coding sequence variant, stop gained
rs1554641737	->G	Likely-pathogenic	Coding sequence variant, frameshift variant
rs1554641887	A>G	Pathogenic-likely-pathogenic	Splice donor variant
rs1554642300	->G	Likely-pathogenic	Coding sequence variant, frameshift variant
rs1554643354	G>C	Pathogenic	Coding sequence variant, stop gained
rs1554643360	G>A	Pathogenic	Coding sequence variant, stop gained
rs1554643370	C>A	Likely-pathogenic	Splice acceptor variant
rs1554643619	G>A	Likely-pathogenic	Coding sequence variant, missense variant
rs1554643738	A>T	Likely-pathogenic	Splice donor variant
rs1554644678	C>T	Likely-pathogenic	Intron variant
rs1554646529	C>A	Pathogenic, likely-pathogenic	Coding sequence variant, stop gained
rs1554646653	G>C	Likely-pathogenic	Coding sequence variant, missense variant
rs1554646710	A>C	Pathogenic	Splice donor variant
rs1554648060	G>C	Likely-pathogenic	Coding sequence variant, missense variant
rs1554649675	C>G	Likely-pathogenic	Splice acceptor variant
rs1554652870	G>A,T	Uncertain-significance, likely-pathogenic	Coding sequence variant, missense variant, stop gained
rs1563834980	->G	Pathogenic	Coding sequence variant, frameshift variant
rs1563849699	CTG>-	Likely-pathogenic	Coding sequence variant, inframe deletion
rs1563864784	->TATT	Pathogenic	Coding sequence variant, frameshift variant
rs1587922096	T>C	Likely-pathogenic	Missense variant, coding sequence variant
rs1587950355	C>G	Likely-pathogenic	Missense variant, coding sequence variant
rs1587951033	A>-	Pathogenic	Frameshift variant, coding sequence variant
rs1587958061	C>A	Pathogenic	Splice acceptor variant
rs1587959976	A>T	Pathogenic	Splice donor variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT042509	hsa-miR-423-3p	CLASH	23622248
MIRT042509	hsa-miR-423-3p	CLASH	23622248
MIRT2235284	hsa-miR-3190	CLIP-seq
MIRT2235285	hsa-miR-4491	CLIP-seq
MIRT2235286	hsa-miR-4657	CLIP-seq
MIRT2235287	hsa-miR-671-5p	CLIP-seq
MIRT2539021	hsa-miR-1304	CLIP-seq
MIRT2539022	hsa-miR-143	CLIP-seq
MIRT2539023	hsa-miR-2467-5p	CLIP-seq
MIRT2539024	hsa-miR-3188	CLIP-seq
MIRT2539025	hsa-miR-342-5p	CLIP-seq
MIRT2539026	hsa-miR-3975	CLIP-seq
MIRT2539027	hsa-miR-4505	CLIP-seq
MIRT2539028	hsa-miR-4651	CLIP-seq
MIRT2539029	hsa-miR-4664-5p	CLIP-seq
MIRT2539030	hsa-miR-4731-5p	CLIP-seq
MIRT2539031	hsa-miR-4770	CLIP-seq
MIRT2539032	hsa-miR-485-5p	CLIP-seq
MIRT2539033	hsa-miR-608	CLIP-seq
MIRT2539021	hsa-miR-1304	CLIP-seq
MIRT2539022	hsa-miR-143	CLIP-seq
MIRT2539023	hsa-miR-2467-5p	CLIP-seq
MIRT2539024	hsa-miR-3188	CLIP-seq
MIRT2539025	hsa-miR-342-5p	CLIP-seq
MIRT2539026	hsa-miR-3975	CLIP-seq
MIRT2539027	hsa-miR-4505	CLIP-seq
MIRT2539028	hsa-miR-4651	CLIP-seq
MIRT2539029	hsa-miR-4664-5p	CLIP-seq
MIRT2539030	hsa-miR-4731-5p	CLIP-seq
MIRT2539031	hsa-miR-4770	CLIP-seq
MIRT2539032	hsa-miR-485-5p	CLIP-seq
MIRT2539033	hsa-miR-608	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004375	Function	Glycine dehydrogenase (decarboxylating) activity	IBA	21873635
GO:0004375	Function	Glycine dehydrogenase (decarboxylating) activity	IDA	28244183
GO:0005654	Component	Nucleoplasm	IDA
GO:0005739	Component	Mitochondrion	IBA	21873635
GO:0005739	Component	Mitochondrion	IDA	28244183
GO:0005759	Component	Mitochondrial matrix	TAS
GO:0005886	Component	Plasma membrane	IDA
GO:0005960	Component	Glycine cleavage complex	IBA	21873635
GO:0006546	Process	Glycine catabolic process	IDA	28244183
GO:0009055	Function	Electron transfer activity	TAS	2268343
GO:0016594	Function	Glycine binding	IBA	21873635
GO:0016829	Function	Lyase activity	IEA
GO:0019464	Process	Glycine decarboxylation via glycine cleavage system	IBA	21873635
GO:0019899	Function	Enzyme binding	IEA
GO:0022900	Process	Electron transport chain	IEA
GO:0030170	Function	Pyridoxal phosphate binding	IBA	21873635
GO:0036255	Process	Response to methylamine	ISS
GO:0042803	Function	Protein homodimerization activity	ISS
GO:0065003	Process	Protein-containing complex assembly	IEA
GO:0070280	Function	Pyridoxal binding	ISS
GO:1903442	Process	Response to lipoic acid	ISS

Other IDs

• MIM: 238300
• HGNC: 4313
• e!Ensembl: ENSG00000178445

Protein

• UniProt ID: P23378
• Protein name: Glycine dehydrogenase (decarboxylating), mitochondrial (EC 1.4.4.2) (Glycine cleavage system P protein) (Glycine decarboxylase) (Glycine dehydrogenase (aminomethyl-transferring))
• Protein function: The glycine cleavage system catalyzes the degradation of glycine. The P protein (GLDC) binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to
• PDB: 6I33, 6I34, 6I35
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02347	GDC-P	65 → 488	Glycine cleavage system P-protein	Domain
  PF01212	Beta_elim_lyase	584 → 743	Beta-eliminating lyase	Domain

• Sequence:

  MQSCARAWGLRLGRGVGGGRRLAGGSGPCWAPRSRDSSSGGGDSAAAGASRLLERLLPRH
  DDFARRHIGPGDKDQREMLQTLGLASIDELIEKTVPANIRLKRPLKMEDPVCENEILATL
  HAISSKNQIWRSYIGMGYYNCSVPQTILRNLLENSGWITQYTPYQPEVSQGRLESLLNYQ
  TMVCDITGLDMANASLLDEGTAAAEALQLCYRHNKRRKFLVDPRCHPQTIAVVQTRAKYT
  GVLTELKLPCEMDFSGKDVSGVLFQYPDTEGKVEDFTELVERAHQSGSLACCATDLLALC
  ILRPPGEFGVDIALGSSQRFGVPLGYGGPHAAFFAVRESLVRMMPGRMVGVTRDATGKEV
  YRLALQTREQHIRRDKATSNICTAQALLANMAAMFAIYHGSHGLEHIARRVHNATLILSE
  GLKRAGHQLQHDLFFDTLKIQCGCSVKEVLGRAAQRQINFRLFEDGTLGISLDETVNEKD
  LDDLLWIFGCESSAELVAESMGEECRGIPGSVFKRTSPFLTHQVFNSYHSETNIVRYMKK
  LENKDISLVHSMIPLGSCTMKLNSSSELAPITWKEFANIHPFVPLDQAQGYQQLFRELEK
  DLCELTGYDQVCFQPNSGAQGEYAGLATIRAYLNQKGEGHRTVCLIPKSAHGTNPASAHM
  AGMKIQPVEVDKYGNIDAVHLKAMVDKHKENLAAIMITYPSTNGVFEENISDVCDLIHQH
  GGQVYLDGANMNAQVGICRPGDFGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKKHLAPFL
  PNHPVISLKRNEDACPVGTVSAAPWGSSSILPISWAYIKMMGGKGLKQATETAILNANYM
  AKRLETHYRILFRGARGYVGHEFILDTRPFKKSANIEAVDVAKRLQDYGFHAPTMSWPVA
  GTLMVEPTESEDKAELDRFCDAMISIRQEIADIEEGRIDPRVNPLKMSPHSLTCVTSSHW
  DRPYSREVAAFPLPFVKPENKFWPTIARIDDIYGDQHLVCTCPPMEVYESPFSEQKRASS
  

• Sequence length: 1020

Pathways

KEGG:

Glycine, serine and threonine metabolism
Glyoxylate and dicarboxylate metabolism
One carbon pool by folate
Lipoic acid metabolism
Metabolic pathways
Carbon metabolism

Reactome:

Glycine degradation

Associated diseases

Causal
Disease term	Disease name	dbSNP ID	References
Agenesis of corpus callosum	Agenesis of corpus callosum	rs754914260, rs1057519053, rs1057519056, rs1057519054, rs1057519055, rs1057519057, rs1384496494, rs1599017933
Epilepsy	Epilepsy, Generalized	rs113994140, rs28937874, rs1589762127, rs104894166, rs28939075, rs2134001459, rs104894167, rs119488099, rs119488100, rs387906420, rs121917752, rs121918622, rs281865564, rs387907313, rs397514670, rs768241563, rs587776973, rs587776974, rs587776975, rs879255234, rs587776976, rs587776977, rs121917993, rs398123588, rs13306758, rs587777458, rs587777459, rs541024038, rs797044545, rs730882240, rs786205703, rs794726859, rs796053126, rs796053035, rs796053216, rs796052839, rs869025201, rs797044999, rs797044998, rs797045045, rs794726762, rs869312971, rs869312972, rs879255652, rs886037938, rs886037958, rs886037959, rs886037960, rs886037961, rs886037962, rs886037965, rs886037966, rs886039245, rs886039246, rs886039251, rs886039252, rs772872014, rs886039253, rs886039256, rs757511744, rs886039261, rs886039263, rs578185749, rs886039266, rs886039268, rs886039269, rs886039273, rs368820286, rs1057518801, rs1057518688, rs1057519107, rs1057519273, rs752753379, rs767795673, rs1057519424, rs755946598, rs760609867, rs1057521066, rs1057524233, rs1060501488, rs1060501487, rs755127868, rs751533302, rs771373457, rs1475605360, rs1555401942, rs1553567864, rs200661329, rs766667249, rs1556607762, rs1555882921, rs1555882867, rs1555900914, rs1553546836, rs77216276, rs755595256, rs747661902, rs2105890565, rs1021001959, rs1555441032, rs1555439541, rs1556526609, rs1315483224, rs759952667, rs1555885023, rs1553456695, rs1555942720, rs1569083500, rs1559127505, rs1206309859, rs1567139896, rs1567134495, rs1431914212, rs1569166925, rs1569255443, rs1568955379, rs1567152003, rs374158137, rs1567129567, rs1569523728, rs1568991466, rs1569186093, rs1569254004, rs1372605067, rs1569067939, rs1568963062, rs1563959514, rs1569012755, rs1559118914, rs1602338615, rs1596522356, rs1364913665, rs1596522300, rs1596526976, rs1229740428, rs1596385588, rs1596500172, rs1596505517, rs1601925213, rs1601970168, rs1602010382, rs1602903591, rs1603014297, rs1603014708, rs1601875057, rs1601970824, rs1601755632, rs1587393982, rs1592977444, rs1575562076, rs1570998206, rs1588057922, rs1596528731, rs1602349641, rs1587401875, rs2065899210, rs1596526915, rs2093486364, rs2056165149, rs2056100951, rs781482552, rs1899868619, rs1900088045, rs1898675878, rs1898686157, rs1898837245, rs1898844513, rs2082841677, rs2085727988, rs2092933941, rs2091657024, rs1899864955, rs1898844907, rs2083056830, rs2084070588, rs1899713412, rs2082695884, rs1977106116, rs1977105425, rs1443687532	10873393
Epileptic encephalopathy	Encephalopathies	rs587776508, rs121918334, rs121918317, rs121918321, rs74315390, rs28939684, rs74315391, rs74315392, rs118192244, rs121918622, rs121918623, rs121917953, rs121917955, rs121918624, rs121918625, rs121918626, rs121918629, rs121918632, rs118192218, rs118192219, rs118192222, rs118192226, rs118192228, rs118192234, rs118192236, rs118192235, rs118192242, rs118192185, rs118192188, rs118192246, rs118192186, rs118192194, rs118192199, rs118192201, rs118192202, rs118192203, rs118192204, rs118192205, rs118192206, rs118192208, rs118192215, rs118192216, rs118192239, rs397514458, rs387906686, rs202151337, rs121917957, rs121917929, rs121917927, rs121917966, rs121917941, rs121917964, rs121917943, rs121917965, rs121917918, rs121917963, rs121917911, rs121917912, rs121917986, rs121917987, rs121917913, rs121917945, rs121917996, rs121917975, rs121917919, rs121917993, rs121917915, rs121917995, rs121917976, rs121917994, rs121917926, rs121917951, rs121917952, rs121917980, rs121917921, rs121917935, rs121917936, rs121917984, rs121917937, rs121917985, rs121917938, rs121917928, rs121918753, rs121918781, rs121918782, rs121918784, rs121918734, rs121918788, rs121917969, rs121918775, rs121918786, rs121918796, rs121918745, rs121918740, rs121918741, rs121918789, rs121918742, rs121918791, rs121918811, rs121917922, rs121918744, rs121918778, rs121918767, rs121918779, rs121918770, rs121918783, rs121918773, rs121918793, rs267606051, rs398123585, rs398123588, rs398123593, rs587777164, rs587777219, rs587777310, rs587780446, rs587777492, rs587777495, rs587777577, rs267608501, rs587777721, rs587783192, rs587783200, rs104894745, rs587784453, rs587784454, rs587784438, rs587784440, rs727504136, rs727503974, rs727504140, rs727504173, rs201497300, rs786204967, rs794726739, rs794726845, rs779614747, rs794726726, rs794726763, rs794726754, rs794726760, rs794726759, rs199727342, rs794726800, rs794726752, rs794726825, rs794726809, rs794726696, rs794726699, rs794726705, rs794726784, rs794726779, rs794726821, rs146878122, rs794726816, rs794726744, rs794726854, rs794726710, rs794726733, rs542420576, rs794726772, rs794726842, rs794726718, rs794726761, rs794726697, rs794726775, rs397514459, rs767045134, rs794726766, rs794726742, rs794726730, rs794726778, rs794726736, rs794726773, rs794726790, rs794726826, rs794726753, rs794726799, rs794726844, rs794726782, rs794726798, rs794726824, rs794726827, rs794726803, rs794726711, rs794726762, rs786205598, rs863223345, rs794727128, rs794727337, rs794727361, rs794727444, rs794727740, rs794727792, rs794727970, rs863225068, rs796053181, rs796053130, rs796053048, rs796053086, rs796053103, rs796053043, rs796053085, rs796053035, rs796053031, rs796053029, rs796053022, rs139300715, rs796053014, rs1553522472, rs796053010, rs121917908, rs796053008, rs794726789, rs796053004, rs796053072, rs796052995, rs796053067, rs796052990, rs796052987, rs796052985, rs796053065, rs1553543316, rs796053064, rs796052977, rs796052976, rs796052973, rs796052972, rs781746113, rs796052960, rs796052959, rs796053054, rs1553551312, rs796052953, rs758871507, rs796053350, rs1554776228, rs796053352, rs796053390, rs796053353, rs796053359, rs796053361, rs796053366, rs796053367, rs796053370, rs796053368, rs796053373, rs796053376, rs796053377, rs1554768992, rs796053335, rs796053233, rs796053214, rs796053216, rs796053224, rs796053228, rs796053229, rs796052658, rs796052670, rs796052654, rs796052653, rs796052652, rs773171451, rs1555853593, rs759584387, rs796052650, rs118192233, rs796052657, rs796052644, rs796052645, rs796052641, rs796052640, rs775918190, rs796052636, rs796052626, rs796052623, rs796052621, rs796052620, rs796052618, rs796052617, rs796052663, rs797044983, rs797045013, rs797044878, rs797044951, rs797044873, rs797044938, rs797045969, rs118192212, rs863225037, rs863225036, rs863225030, rs863225031, rs864321707, rs864321712, rs869312684, rs869312920, rs869312939, rs878853250, rs878854263, rs878854262, rs751170778, rs878854974, rs878855236, rs1555794286, rs879255652, rs879255695, rs879255697, rs879255704, rs879255705, rs879255709, rs879255710, rs886039323, rs886039435, rs886039494, rs886039903, rs1135401734, rs1135401733, rs1135401732, rs886042004, rs886041716, rs886041961, rs886041668, rs886041246, rs886041339, rs886041766, rs886041262, rs886041715, rs886042528, rs886042605, rs886063501, rs1555850151, rs1057516123, rs1555853971, rs1057516115, rs1057516106, rs1057516105, rs1057516099, rs1057516098, rs1057516094, rs1057516089, rs1057516086, rs1057516085, rs1057516080, rs1057516079, rs1057516076, rs1057518325, rs1057517862, rs1057517849, rs1057518243, rs1057518258, rs1057517958, rs121917974, rs1057517959, rs796053374, rs1057517919, rs1057518489, rs1057518801, rs1057518816, rs759766243, rs1057518795, rs1057518985, rs1057519000, rs1057519269, rs1057519270, rs1057519452, rs375659415, rs1057519501, rs1057519528, rs1057519526, rs1057519527, rs1057519524, rs796053083, rs1057519529, rs1057519531, rs1057519547, rs1057519548, rs1057519545, rs1057519538, rs1057519539, rs1057519537, rs1057519540, rs1057519549, rs1057519550, rs1057519535, rs1057519536, rs1057519542, rs778291283, rs1057520486, rs794726765, rs750209664, rs121917753, rs1057521746, rs1057523858, rs1057520753, rs1057520413, rs1057521080, rs1057524599, rs778481061, rs768633670, rs796052655, rs1060502190, rs1060502183, rs121918780, rs1060502185, rs1057521537, rs1060502187, rs121918765, rs1060502182, rs121917981, rs1060502188, rs1060502189, rs1060503108, rs1060501724, rs1060501722, rs1060501723, rs1060501012, rs1060504137, rs1060500603, rs1060500602, rs1060499592, rs796053138, rs1064795579, rs1553520298, rs121918805, rs1064795733, rs1064796177, rs1064795735, rs1064794634, rs1064796384, rs1064796213, rs1064793923, rs1064794727, rs1064794533, rs1064795384, rs1555850842, rs1064794001, rs1064796151, rs1064795435, rs1064797284, rs1085307930, rs1085307730, rs1085307916, rs1085307876, rs1085307920, rs1131691773, rs1131691774, rs1131691675, rs1131691775, rs1131691693, rs1131691465, rs1131691830, rs1131691936, rs1057523728, rs1199412903, rs1555228303, rs1555507477, rs1554965669, rs1555499800, rs1553923787, rs922847767, rs368609628, rs1553286282, rs1266877537, rs794726749, rs1553551425, rs1553552390, rs1554778657, rs1555889130, rs1555881741, rs1553520320, rs1553522517, rs796053006, rs1553534296, rs1553541028, rs1553544579, rs1553551385, rs1553520380, rs1553525210, rs1553541473, rs761333438, rs1553520982, rs1553522321, rs1553520318, rs1553540503, rs1553540389, rs1553542199, rs1553543215, rs1553541172, rs1553549483, rs750901301, rs794726743, rs1553545660, rs1553561023, rs1553548096, rs1553552319, rs1553560760, rs1554037381, rs1554776948, rs1554778417, rs1057522982, rs1555219147, rs1555218657, rs1555850590, rs1555869758, rs1555873823, rs1553525325, rs794727813, rs1555228771, rs1553520530, rs1555870346, rs1555955296, rs1553551493, rs1555546796, rs1555870554, rs1555871832, rs77216276, rs1554689320, rs1554777496, rs1555881809, rs1553529461, rs12131800, rs1553517274, rs1555889127, rs1555951141, rs1553590192, rs1553531178, rs1555870470, rs927722314, rs1553523142, rs1041924436, rs1553544559, rs1553544821, rs1553520319, rs1553560677, rs1553521567, rs1553522331, rs1553519872, rs1553529426, rs1553519902, rs1553520029, rs1553545522, rs1553520439, rs146515561, rs1553549461, rs1553549834, rs1553546789, rs1553553614, rs1553560676, rs1553520227, rs1553524865, rs1553525036, rs1553560740, rs1553561016, rs1193718145, rs1554769099, rs936639741, rs1352024223, rs758779535, rs1555870506, rs747376305, rs1555869700, rs1555873656, rs1555873981, rs536000212, rs959316981, rs1554777470, rs1555889108, rs1559144583, rs1569219844, rs1564346538, rs1562159088, rs1559101839, rs1559114303, rs1559140110, rs1559140306, rs1043031572, rs121918756, rs1559199628, rs1559200672, rs796053095, rs1559210063, rs1559225495, rs1553549471, rs1559103294, rs1559105368, rs121918764, rs1559114837, rs1559122124, rs1559127505, rs1559128532, rs1559140855, rs1559149128, rs1559217391, rs1559220874, rs794726695, rs1559249734, rs1553553527, rs1559101585, rs1559110846, rs1559193050, rs1559216338, rs1559231284, rs148442069, rs1559105301, rs1559114202, rs121917954, rs1559195296, rs1553546763, rs1559238432, rs1559884460, rs1559887808, rs1564352002, rs1564349850, rs1564351103, rs1565933795, rs1565886685, rs1555228668, rs587777723, rs1564333757, rs375363057, rs1568932480, rs1568925719, rs770187706, rs1568864658, rs1568899375, rs118192209, rs1568932462, rs1568927747, rs1057518555, rs1559119345, rs1085307520, rs1559200901, rs970867558, rs1568940442, rs775162839, rs1568986619, rs1558308998, rs1553546668, rs1569017015, rs1569017045, rs1569017073, rs1555889090, rs1569017143, rs1569017148, rs1569017205, rs1179351306, rs1569017257, rs1569017337, rs1555889162, rs1568658507, rs1485894376, rs1561139569, rs1574716488, rs1553519865, rs1573946994, rs1573948129, rs121918812, rs1573950349, rs1573952908, rs1573964264, rs1573964628, rs372425457, rs1573984004, rs1574004452, rs1574005235, rs1574006637, rs1574006857, rs1574039742, rs121918801, rs1574051496, rs1574051665, rs1574060250, rs1574060717, rs1574169179, rs1574170908, rs121918774, rs1574192005, rs1574192998, rs1574201591, rs1574216450, rs1574223964, rs1574224274, rs1574225593, rs748267258, rs1553547380, rs1574263819, rs1574265144, rs762927460, rs1574266490, rs1574271827, rs1574302195, rs1574371399, rs1575603683, rs763339068, rs1588313568, rs1589416130, rs1592380672, rs1592148206, rs1592149793, rs1592149906, rs1592162415, rs1592162506, rs1596787821, rs1600755607, rs1600755429, rs1600731888, rs1601573302, rs1601566621, rs1601542702, rs1601542417, rs1600886270, rs1600766500, rs1574370981, rs1573962555, rs1574068971, rs1057524737, rs1574263047, rs1575601202, rs1554777464, rs1589393179, rs1597696047, rs1247507359, rs752927520, rs1473654961, rs1592380834, rs796053036, rs1573953706, rs1573973548, rs1573984110, rs1574007140, rs1574166948, rs745378416, rs1574209023, rs796053094, rs1574264920, rs1600714727, rs755159935, rs1574281711, rs779324355, rs1053767552, rs201894374, rs770456604, rs113094436, rs1578264574, rs1260191836, rs1578265048, rs1578265068, rs1578269200, rs1186496501, rs1578269761, rs756467468, rs1381665298, rs1578270476, rs1578274054, rs769243823, rs200059198, rs749975104, rs1578282133, rs1306655122, rs1600785769, rs1580990072, rs1584399108, rs1057519189, rs1595440453, rs1596872804, rs1597653264, rs1597676610, rs1599719527, rs1600755440, rs1600786071, rs770904422, rs1574525321, rs1840653547, rs749965674, rs1841611651, rs1841766225, rs1852152679, rs1853919580, rs1858669268, rs1941650264, rs1941714576, rs1938725748, rs2037920694, rs2037920791, rs2079949302, rs2079962041, rs2079972258, rs2080188103, rs2080189052, rs1057520773, rs2081071680, rs2081187047, rs2081187692, rs2081358991, rs2081378550, rs1698943949, rs1698602170, rs1698192456, rs1698176171, rs1369404945, rs1698003832, rs1698002491, rs1697999557, rs398123581, rs1697674296, rs1697473667, rs1697277384, rs1697160366, rs1697157422, rs1426666349, rs1697134047, rs1696883051, rs1696628056, rs794726823, rs1696403750, rs897883046, rs1696401617, rs1696356978, rs1696338792, rs1693176153, rs1692577292, rs1240187329, rs1553529527, rs1692166604, rs1691093633, rs1691039670, rs1690583220, rs1690345764, rs1690011364, rs1553521530, rs1553521051, rs1386425283, rs1573952473, rs1689300152, rs1689298888, rs1689285717, rs1689278461, rs1238612161, rs1689271621, rs1253117981, rs1689218857, rs1689211960, rs1689211569, rs1689200375, rs1689142827, rs1684673339, rs1684663586, rs1699367901, rs1553553462, rs1699149959, rs1698958802, rs746440689, rs1692586274, rs1697876590, rs727504142, rs1689985819, rs794726764, rs1704944478, rs1178244073, rs1840967817, rs2080693649, rs1938214529, rs2080696874, rs2081190512, rs1691073965, rs1689488709, rs1691048388, rs1692581621, rs1692870117, rs121918785, rs749539763, rs1842042825, rs2081190344, rs1600789325
Glycine encephalopathy	Atypical glycine encephalopathy, Neonatal glycine encephalopathy, Infantile glycine encephalopathy	rs121964983, rs121964984, rs121964985, rs121964986, rs181134220, rs386833679, rs386833682, rs386833683, rs386833684, rs386833686, rs1057519313, rs1057519314, rs1057519315, rs781466698, rs757918826, rs866625610, rs201437896, rs773988915
Mental retardation	Intellectual Disability	rs5742905, rs267607136, rs267607137, rs2131714307, rs267607038, rs267607042, rs80338685, rs137853127, rs80338815, rs28940893, rs387906309, rs121908096, rs121908099, rs587784365, rs121918315, rs121918316, rs397515320, rs121434489, rs1585215916, rs267607233, rs267606752, rs137852214, rs606231193, rs132630297, rs80338758, rs137852815, rs122455132, rs28935171, rs122453113, rs122445108, rs28934904, rs28934908, rs28935468, rs61748421, rs121918624, rs202060209, rs80338708, rs113994198, rs199422192, rs387906635, rs1554770064, rs1057519611, rs1060499526, rs387906636, rs1057519612, rs281875189, rs281875322, rs387906799, rs387906804, rs875989800, rs797045262, rs387906845, rs387906846, rs876657378, rs281875227, rs281875228, rs281875229, rs281875230, rs387906861, rs370667926, rs387906932, rs387906943, rs1557612719, rs387907190, rs387907191, rs2126499522, rs587776908, rs1560982564, rs80359505, rs398123009, rs587776929, rs587776930, rs397514555, rs398122824, rs398122825, rs397514556, rs2147483647, rs587776937, rs397514627, rs397514655, rs397514656, rs730882192, rs1587520018, rs1581995953, rs1554121970, rs1581987445, rs397514670, rs376395543, rs137854128, rs397509411, rs397509412, rs397514741, rs398122394, rs879255516, rs397518483, rs398122406, rs398122412, rs398123561, rs200667343, rs587777162, rs587777202, rs62507350, rs587777219, rs587777225, rs587777226, rs587779750, rs587777326, rs587777334, rs281875332, rs587780470, rs587780474, rs587780486, rs587777378, rs587777406, rs587777408, rs587777409, rs587777411, rs587777522, rs527236034, rs527236035, rs267608571, rs267608382, rs267608597, rs61753979, rs61751444, rs267608493, rs587777644, rs587777645, rs587777646, rs587777703, rs587779388, rs606231266, rs606231267, rs672601340, rs606231268, rs672601341, rs606231269, rs672601342, rs606231270, rs606231271, rs606231272, rs606231273, rs587784566, rs587784092, rs587783749, rs587783747, rs587783640, rs587783483, rs606231456, rs606231457, rs606231458, rs606231459, rs672601370, rs672601369, rs672601371, rs672601367, rs672601366, rs672601365, rs672601364, rs672601363, rs672601362, rs672601376, rs672601377, rs672601378, rs724159949, rs724159950, rs724159948, rs724159956, rs724159953, rs727502860, rs727502861, rs730882197, rs749995448, rs786205143, rs794726770, rs1135401808, rs786205583, rs786205595, rs786205859, rs794727792, rs794727928, rs794729221, rs797044519, rs797044523, rs797044521, rs797044524, rs797044526, rs797044522, rs797044520, rs794727642, rs796052719, rs781746113, rs796052510, rs796052733, rs796052724, rs796052728, rs796052676, rs796053353, rs796053366, rs796053368, rs1555103986, rs1555110818, rs796052571, rs1555110843, rs796052626, rs796052618, rs796053290, rs796052217, rs672601368, rs797045164, rs797044961, rs797044962, rs200070245, rs797044963, rs869320675, rs869320676, rs797045012, rs752746786, rs797044885, rs797044925, rs797044854, rs797044849, rs797044930, rs797044901, rs797044918, rs797044884, rs797045177, rs797045178, rs797045050, rs797045036, rs797045053, rs797045047, rs797045037, rs797045042, rs797045041, rs879255261, rs782397980, rs797045263, rs797045264, rs797045655, rs797045586, rs545185248, rs797046031, rs797046028, rs797046029, rs797046030, rs797045249, rs797045529, rs797045952, rs797045984, rs797045540, rs797045539, rs797045989, rs863224930, rs869025202, rs863225264, rs863225077, rs876661308, rs869025222, rs864309560, rs758252808, rs745756308, rs869025286, rs869025287, rs869025578, rs143038880, rs869025579, rs869025580, rs869025581, rs869312704, rs869312674, rs869312677, rs869312689, rs869312693, rs869312698, rs869312708, rs869312711, rs869312826, rs869312825, rs869312824, rs869312823, rs758432471, rs869312821, rs761993070, rs869312844, rs869312842, rs869312843, rs869312841, rs869312847, rs869320632, rs869312955, rs773432002, rs869320713, rs869320772, rs869320773, rs879255270, rs875989848, rs875989849, rs1716457622, rs2108414289, rs878854401, rs875989786, rs1085307109, rs1085307108, rs876657679, rs876661167, rs876661076, rs876661055, rs876661219, rs876661064, rs876661151, rs876661041, rs200440467, rs876661295, rs878853045, rs878853143, rs878853142, rs878853149, rs1555910048, rs878853152, rs878853146, rs878853145, rs878853141, rs878853151, rs878853144, rs878853148, rs878853147, rs878853251, rs878853269, rs879253762, rs886037841, rs879253888, rs879253931, rs879254016, rs879255618, rs879255619, rs879255620, rs886037847, rs879255621, rs886039332, rs746177928, rs886039520, rs886041003, rs886041058, rs750035706, rs886041059, rs886041060, rs886041061, rs886041090, rs886041088, rs886041089, rs886041095, rs886041097, rs886041989, rs886041944, rs886041692, rs886041593, rs886041687, rs886041207, rs886041309, rs886041239, rs886041448, rs138336847, rs149644940, rs886041295, rs886041521, rs886041125, rs886042041, rs886041238, rs886041469, rs886041197, rs886041291, rs886041658, rs886041705, rs886041876, rs139716296, rs1057516030, rs1057517408, rs749655461, rs141179774, rs370916968, rs1057517676, rs1057517933, rs1057517708, rs1057518352, rs1057518183, rs1057518474, rs1057518204, rs1057517825, rs1057518796, rs1057518961, rs1057518772, rs1057518988, rs1057519004, rs1057518700, rs772450541, rs371310428, rs1057519019, rs1057519491, rs1057519546, rs1057519560, rs1057519565, rs1057519400, rs1057519402, rs1057519405, rs1057519593, rs1057519594, rs1057519628, rs1556912828, rs1060505029, rs1060505030, rs147001633, rs1057519947, rs1057519617, rs1057524832, rs774592932, rs797045045, rs1039571136, rs1555910821, rs1060499626, rs1060499655, rs1554770185, rs1060499936, rs1060501153, rs1060501151, rs1064792984, rs1060503378, rs1060503386, rs1060503383, rs1060500046, rs1064792999, rs1060505033, rs1064796564, rs1064797002, rs1064793161, rs150802299, rs1064796830, rs1064794996, rs1064795444, rs1064796034, rs1064796403, rs1064794979, rs1064796765, rs1064793539, rs760933323, rs1064793546, rs1064796406, rs1064796367, rs780441716, rs1064794894, rs1064796023, rs1064797355, rs1085307484, rs1064794935, rs1085307547, rs1131690804, rs757511770, rs1131691875, rs1131691979, rs398122823, rs1131691866, rs1131692159, rs1131692228, rs1131692154, rs113331868, rs1554121872, rs1554121875, rs926027867, rs1554122123, rs1554122129, rs1287121256, rs1554122526, rs1554123982, rs1554385102, rs1554385111, rs1554385305, rs1554386687, rs1554389088, rs1554402092, rs1554434435, rs1135401778, rs1135401760, rs1135401770, rs1135401771, rs1135401768, rs1135401779, rs1135401805, rs1135401797, rs1135401799, rs1135401816, rs1135401823, rs1135401824, rs1555769968, rs1135401825, rs1135401955, rs1135401956, rs1135401957, rs1135401958, rs1554129040, rs1554150543, rs1553188463, rs1553146165, rs1485978447, rs1361547443, rs750079325, rs369692236, rs1554231836, rs749188610, rs1554122735, rs1554689877, rs1174482090, rs781053477, rs1554623112, rs1555409836, rs1555411305, rs770014321, rs1555984461, rs1555990958, rs762292772, rs1554944271, rs1057524157, rs1485749468, rs1555984343, rs1293450628, rs373584239, rs1553722309, rs1553738686, rs1376334317, rs1553722294, rs1553283831, rs1554120589, rs1555985554, rs1555877287, rs1555411378, rs750922282, rs1553264873, rs1554263326, rs1554264268, rs1554263626, rs1554263625, rs766614772, rs1553620494, rs1555050158, rs1555050165, rs1555050171, rs1555050174, rs765556214, rs1402086660, rs1554645052, rs1555661648, rs1293246328, rs749494995, rs775592405, rs1553265189, rs1553242856, rs1553247374, rs1553241570, rs1553997065, rs1553998565, rs1380822792, rs1555028154, rs1555023232, rs1553194155, rs1553130904, rs1553152590, rs1553567864, rs1553638614, rs120074160, rs1554486894, rs1554767754, rs1554843977, rs1555443581, rs1555443600, rs1555439545, rs1555525088, rs770680174, rs1555889130, rs373178770, rs1555985532, rs1553519853, rs781325598, rs1410587479, rs1553638086, rs150259543, rs1554093891, rs1554121228, rs1554120498, rs1554121189, rs1212517874, rs1554770628, rs1555979158, rs1554770054, rs771610568, rs1451230055, rs1554770624, rs1555906707, rs1555906768, rs1555906781, rs1555907620, rs1555907623, rs1555907626, rs1555907653, rs1555907864, rs1554094145, rs1554202698, rs1554200722, rs773327091, rs1555607621, rs1555604778, rs1555607159, rs1555607682, rs1553364018, rs1553324416, rs1555411394, rs1554102556, rs1554122363, rs1555705966, rs1555103971, rs1555408401, rs1554461593, rs1554304254, rs1554120978, rs1047509819, rs1555982601, rs767774867, rs1554789246, rs1555111511, rs1555950676, rs1555954380, rs1555985649, rs1553194162, rs1553518509, rs1274633498, rs1554274371, rs1554122252, rs1554122458, rs1554122729, rs1554297905, rs1554776342, rs1554770046, rs1554770667, rs1554792556, rs1452715535, rs1555444885, rs1555534147, rs1427624649, rs1555611722, rs1555744282, rs1555706391, rs1178702025, rs1555984102, rs1554770589, rs1554121443, rs1559791842, rs1559824939, rs1555889127, rs1236702036, rs1553510280, rs1553511175, rs1553511226, rs1554150552, rs1554275163, rs1554201137, rs1553517991, rs1553518511, rs1553517984, rs1553518752, rs1554119814, rs1554122293, rs1554122341, rs1554122689, rs1554770243, rs1554770444, rs1557045250, rs959316981, rs1556270312, rs1553270640, rs978179634, rs1554093884, rs1491240980, rs1555943484, rs1554121453, rs1334099693, rs1554048616, rs1555660806, rs1555644480, rs1555651572, rs1567844992, rs1567855081, rs1567855669, rs1567855704, rs1567856045, rs1567856331, rs1567860075, rs1567860112, rs1567860640, rs1567860891, rs754919272, rs1567860919, rs1567861468, rs1567861489, rs1567861501, rs1567861894, rs1567863732, rs1567864750, rs1567877108, rs1567878511, rs758785463, rs1553808301, rs1553245038, rs1553789166, rs1553813646, rs1553631860, rs1554121265, rs1554770262, rs1555034768, rs1555984433, rs779009256, rs1553994814, rs1553996086, rs1553996072, rs1553270599, rs1553153291, rs760262127, rs1554119274, rs1554121878, rs1554387293, rs1554385203, rs757077698, rs750612085, rs1554776500, rs1564360978, rs1554776933, rs1554776938, rs1565278132, rs1567368243, rs1558478047, rs375695605, rs1558479778, rs1558501648, rs1565240833, rs114727354, rs1557591264, rs1557620758, rs1559099927, rs1561788984, rs369459721, rs1563831738, rs1562159088, rs1562159562, rs1562159599, rs1559094754, rs1559328283, rs755634856, rs1561784687, rs1554122296, rs1561789313, rs1562720119, rs1564363665, rs1561697465, rs1561785003, rs1561787845, rs1561789215, rs1554122305, rs1561784553, rs1561784560, rs1561787690, rs1554122888, rs749632782, rs1567139896, rs1569370887, rs1569371303, rs1564493599, rs1561875779, rs1569146542, rs1569146649, rs1275489527, rs1560115921, rs1468772495, rs749969789, rs1560108090, rs1569376809, rs1569355102, rs1560103306, rs1564365418, rs1559855453, rs1562928193, rs1558149913, rs1253072668, rs141976414, rs1558371790, rs1557898800, rs1567758622, rs1567844041, rs1567844114, rs1567920106, rs1567920209, rs138247472, rs1567974030, rs1567995650, rs1283838287, rs1568003569, rs1568006217, rs1568018905, rs1562505675, rs1561783309, rs1555980234, rs1559087186, rs1560966086, rs1560330387, rs769471341, rs1562493608, rs1562505335, rs1554121861, rs1554122200, rs1562957809, rs1568097623, rs1391600900, rs1568234874, rs1568235086, rs1555990955, rs1567870541, rs1557570794, rs1562869207, rs1571818248, rs1431778557, rs369691608, rs1595808957, rs1597665063, rs1597846084, rs1603401125, rs1603350606, rs1601946481, rs1601932069, rs1602880906, rs1602308324, rs1574554519, rs1573882268, rs1603198937, rs1558148010, rs1558498928, rs1569459580, rs1569380375, rs1560062082, rs1557889974, rs1558414255, rs756429763, rs781663444, rs1569016820, rs1569017025, rs1569017160, rs1557612048, rs1568504941, rs1581987022, rs1576983339, rs1599892470, rs1265340906, rs1602284689, rs1574949440, rs1576220938, rs1576280892, rs1576288424, rs1574459612, rs1574511051, rs1575654528, rs1577094794, rs1294683568, rs771819481, rs1580984895, rs1581338441, rs1580988138, rs1581980317, rs1581986872, rs1554121207, rs1581987268, rs1581987476, rs1581987885, rs763770519, rs1581991929, rs1581992099, rs1581992998, rs1581995453, rs1554122242, rs1581996778, rs1581997228, rs1588735247, rs1555980467, rs1555985742, rs1601319086, rs1601970168, rs1574451881, rs876661168, rs1576994053, rs1573589807, rs1581036396, rs1601267617, rs1572531830, rs1573483715, rs1590954686, rs1601315812, rs1573965358, rs1573972562, rs529087882, rs1570609440, rs1598940393, rs1575333081, rs1576028676, rs1596476657, rs1599375711, rs1603290366, rs1603060007, rs1603069440, rs1592939069, rs1591612223, rs2062994512, rs373701249, rs1600471396, rs1600501018, rs1600504088, rs1600514073, rs748436953, rs765723607, rs758170522, rs1561785045, rs1357591960, rs1591609136, rs1596891223, rs1579370234, rs2047850664, rs1579109565, rs1870202051, rs1574887674, rs778229060, rs1572531281, rs1570622663, rs1573501865, rs1576086299, rs1576164991, rs1574907198, rs1576656734, rs1554121438, rs1581995425, rs1581996813, rs1582001015, rs1588324025, rs1591371152, rs1590008294, rs1590956245, rs1590028691, rs1591606580, rs1591611001, rs1591612317, rs1591612370, rs763436882, rs997044541, rs1595897117, rs747706524, rs1579377990, rs1201878175, rs1894051550, rs1572531730, rs1579576029, rs1577017863, rs752545577, rs1582461267, rs1589460606, rs1588727276, rs1598620094, rs1599368323, rs1600082188, rs1601319352, rs1598226304, rs2076013475, rs2076017638, rs1600596180, rs1554121932, rs1680676671, rs1570607996, rs1382444181, rs1570640673, rs1574994308, rs1596667777, rs1602226289, rs1595629181, rs1595609005, rs1227643933, rs1572705473, rs1570621899, rs1722830922, rs1575094649, rs1417035592, rs1581997098, rs1589457762, rs1598211790, rs758726258, rs1601071971, rs863224922, rs1586692481, rs1586692548, rs1586692551, rs1580988074, rs1594129609, rs1588732344, rs1579368865, rs1586660389, rs1586660370, rs1586660338, rs1586657848, rs1586660381, rs1791701214, rs752676391, rs1680673822, rs758098717, rs1726676630, rs762288077, rs1759964009, rs1760905766, rs1761021165, rs1554121934, rs2055849544, rs1049773, rs587784300, rs1861628072, rs1761241410, rs1064797322, rs1948652423, rs2059194330, rs1777174302, rs2054280202, rs2081190512, rs772665884, rs1400164869, rs1861593395, rs1760897843, rs1761087122, rs1388355040, rs2068797192, rs1777175608, rs376898131
Obesity	Obesity	rs74315349, rs1474810899, rs121918111, rs796065034, rs753856820, rs796065035, rs121918112, rs104894023, rs137852821, rs1580764441, rs137852822, rs137852823, rs137852824, rs13447324, rs121913562, rs121913564, rs193922650, rs193922685, rs193922687, rs751160202, rs747681609, rs1553400259, rs13447339, rs370479598, rs1554394014, rs1553174844, rs756232889, rs369841551, rs1557670950, rs1571321748, rs148538980, rs1572820988, rs1591461970, rs1419374563, rs745921568, rs144159890, rs1570714352, rs779783209, rs1573250294, rs1573254045, rs1580744791, rs1580746829	10873393

Unknown
Disease term	Disease name	Evidence	References	Source
Asthma	Asthma		31619474	ClinVar, GWAS
Hyperglycinuria	HYPERGLYCINURIA (disorder)			ClinVar
Glycine Encephalopathy	glycine encephalopathy, glycine encephalopathy 1, neonatal glycine encephalopathy, infantile glycine encephalopathy, atypical glycine encephalopathy			GenCC

Associations from Text Mining
Disease Name	Relationship Type	References
Anti N Methyl D Aspartate Receptor Encephalitis	Associate	31279534
Breast Neoplasms	Associate	25496516
Carcinogenesis	Associate	22225612
Carcinoma Ductal	Associate	25053597
Carcinoma Hepatocellular	Inhibit	30804330
Carcinoma Hepatocellular	Associate	35508111
Carcinoma Lobular	Associate	25053597
Carcinoma Non Small Cell Lung	Associate	22225612
Cerebral Infarction	Associate	26352407
Colorectal Neoplasms	Associate	25117815
Corticobasal Degeneration	Associate	28271184
Endometrial Neoplasms	Associate	31692912
Heredodegenerative Disorders Nervous System	Associate	32421718
Hyperglycinemia Nonketotic	Associate	17361008, 24334290, 26947380, 27362913, 28416785, 28737873, 29232014, 29304759, 31349202, 32421718
Hypertension Pulmonary	Associate	26352407
Lung Neoplasms	Associate	22225612
Neoplasm Metastasis	Associate	30575323, 37781511
Neoplasm Metastasis	Inhibit	30804330
Neoplasms	Associate	22225612, 24979213, 32055850, 35508111, 36275705
Neural Tube Defects	Associate	29232014
Neuroblastoma	Associate	37545226
Neurodegenerative Diseases	Associate	22121227
Osteosarcoma	Associate	29210060
Periodontitis	Associate	27531006
Primary hyperoxaluria type 1	Inhibit	31279534
Prostatic Neoplasms	Associate	37781511
Psychotic Disorders	Associate	31279534
Renal Insufficiency Chronic	Associate	26352407
Schizophrenia	Associate	29232014
Squamous Cell Carcinoma of Head and Neck	Associate	37245006
Supranuclear Palsy Progressive	Associate	28271184
Thyroid Neoplasms	Associate	27277113
Triple Negative Breast Neoplasms	Associate	24390667, 40217479