TINAG (tubulointerstitial nephritis antigen)

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein
Entrez ID 27283
Gene name Tubulointerstitial nephritis antigen
Gene symbol TINAG
Synonyms (NCBI Gene)
TIN-AG
Chromosome 6
Chromosome location 6p12.1
Summary This gene encodes a glycoprotein that is restricted within the kidney to the basement membranes underlying the epithelium of Bowman`s capsule and proximal and distal tubules. Autoantibodies against this protein are found in sera of patients with tubuloint
miRNA miRNA information provided by mirtarbase database.
2
Gene miRNA Gene ontology Other IDs Protein
Show/Hide all (2)
miRTarBase ID miRNA Experiments Reference
MIRT2349249 hsa-miR-1252 CLIP-seq
MIRT2349250 hsa-miR-4517 CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
11
Gene miRNA Gene ontology Other IDs Protein
Show/Hide all (11)
GO ID Ontology Definition Evidence Reference
GO:0000166 Function Nucleotide binding TAS 10652240
GO:0004197 Function Cysteine-type endopeptidase activity TAS 10652240
GO:0005576 Component Extracellular region IEA
GO:0005604 Component Basement membrane IDA 1762287
GO:0005604 Component Basement membrane IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein
MIM HGNC e!Ensembl
606749 14599 ENSG00000137251
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9UJW2
Protein name Tubulointerstitial nephritis antigen (TIN-Ag)
Protein function Mediates adhesion of proximal tubule epithelial cells via integrins alpha3-beta1 and alphaV-beta3. This is a non catalytic peptidase C1 family protein.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01033 Somatomedin_B 61 → 105 Somatomedin B domain Family
PF00112 Peptidase_C1 227 → 467 Papain family cysteine protease Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in the kidney cortex, small intestine and cornea. {ECO:0000269|PubMed:10652240, ECO:0000269|PubMed:10752525, ECO:0000269|PubMed:1762287}.
Sequence
Sequence length 476
Interactions View interactions