Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	27242
Gene name Gene Name - the full gene name approved by the HGNC.	TNF receptor superfamily member 21
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	TNFRSF21
Synonyms (NCBI Gene) Gene synonyms aliases	BM-018, CD358, DR6
Chromosome Chromosome number	6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	6p12.3
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its deat

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miRTarBase ID	miRNA	Experiments	Reference
MIRT002620	hsa-miR-124-3p	Microarray	15685193
MIRT016429	hsa-miR-193b-3p	Microarray	20304954
MIRT020190	hsa-miR-130b-3p	Sequencing	20371350
MIRT002620	hsa-miR-124-3p	Microarray	18668037
MIRT002620	hsa-miR-124-3p	Microarray	15685193
MIRT027534	hsa-miR-98-5p	Microarray	19088304
MIRT028037	hsa-miR-93-5p	Sequencing	20371350
MIRT608425	hsa-miR-8485	HITS-CLIP	22927820
MIRT608425	hsa-miR-8485	HITS-CLIP	23313552
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT664409	hsa-miR-548c-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT620601	hsa-miR-3065-5p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT620601	hsa-miR-3065-5p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	24906430
MIRT608425	hsa-miR-8485	HITS-CLIP	24906430
MIRT565284	hsa-miR-4694-3p	PAR-CLIP	20371350
MIRT565283	hsa-miR-5583-3p	PAR-CLIP	20371350
MIRT565282	hsa-miR-8076	PAR-CLIP	20371350
MIRT565281	hsa-miR-3688-3p	PAR-CLIP	20371350
MIRT565280	hsa-miR-4698	PAR-CLIP	20371350
MIRT565279	hsa-miR-605-3p	PAR-CLIP	20371350
MIRT565278	hsa-miR-1468-3p	PAR-CLIP	20371350
MIRT565277	hsa-miR-4434	PAR-CLIP	20371350
MIRT565275	hsa-miR-4516	PAR-CLIP	20371350
MIRT565276	hsa-miR-5703	PAR-CLIP	20371350
MIRT565274	hsa-miR-3653-3p	PAR-CLIP	20371350
MIRT565273	hsa-miR-4531	PAR-CLIP	20371350
MIRT439412	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT546261	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT439410	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT028037	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT546260	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT546259	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT546258	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT546257	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT546256	hsa-miR-3609	PAR-CLIP	21572407
MIRT546255	hsa-miR-548ah-5p	PAR-CLIP	21572407
MIRT546254	hsa-miR-4796-3p	PAR-CLIP	21572407
MIRT546253	hsa-miR-3606-3p	PAR-CLIP	21572407
MIRT546252	hsa-miR-513a-3p	PAR-CLIP	21572407
MIRT546251	hsa-miR-513c-3p	PAR-CLIP	21572407
MIRT546250	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT546249	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT546248	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT546247	hsa-miR-217	PAR-CLIP	21572407
MIRT546245	hsa-miR-6807-3p	PAR-CLIP	21572407
MIRT546246	hsa-miR-5579-5p	PAR-CLIP	21572407
MIRT546244	hsa-miR-4729	PAR-CLIP	21572407
MIRT546243	hsa-miR-20a-3p	PAR-CLIP	21572407
MIRT546242	hsa-miR-4635	PAR-CLIP	21572407
MIRT546241	hsa-miR-584-5p	PAR-CLIP	21572407
MIRT439412	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT546261	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT439410	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT028037	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT546260	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT546259	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT546258	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT546257	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT546256	hsa-miR-3609	PAR-CLIP	21572407
MIRT546255	hsa-miR-548ah-5p	PAR-CLIP	21572407
MIRT546254	hsa-miR-4796-3p	PAR-CLIP	21572407
MIRT546253	hsa-miR-3606-3p	PAR-CLIP	21572407
MIRT546252	hsa-miR-513a-3p	PAR-CLIP	21572407
MIRT546251	hsa-miR-513c-3p	PAR-CLIP	21572407
MIRT546250	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT546249	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT546248	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT546247	hsa-miR-217	PAR-CLIP	21572407
MIRT546245	hsa-miR-6807-3p	PAR-CLIP	21572407
MIRT546246	hsa-miR-5579-5p	PAR-CLIP	21572407
MIRT546244	hsa-miR-4729	PAR-CLIP	21572407
MIRT546243	hsa-miR-20a-3p	PAR-CLIP	21572407
MIRT546242	hsa-miR-4635	PAR-CLIP	21572407
MIRT546241	hsa-miR-584-5p	PAR-CLIP	21572407
MIRT439412	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT439410	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT439412	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT546261	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT546258	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT028037	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT546259	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT439410	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT620601	hsa-miR-3065-5p	HITS-CLIP	27418678
MIRT575065	hsa-miR-329-3p	HITS-CLIP	27418678
MIRT575065	hsa-miR-329-3p	HITS-CLIP	27418678
MIRT575065	hsa-miR-329-3p	HITS-CLIP	27418678
MIRT575065	hsa-miR-329-3p	HITS-CLIP	27418678
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	27418678
MIRT575064	hsa-miR-362-3p	HITS-CLIP	27418678
MIRT575064	hsa-miR-362-3p	HITS-CLIP	27418678
MIRT575064	hsa-miR-362-3p	HITS-CLIP	27418678
MIRT575064	hsa-miR-362-3p	HITS-CLIP	27418678
MIRT664409	hsa-miR-548c-3p	HITS-CLIP	27418678
MIRT575066	hsa-miR-8485	HITS-CLIP	27418678
MIRT575066	hsa-miR-8485	HITS-CLIP	27418678
MIRT575066	hsa-miR-8485	HITS-CLIP	27418678
MIRT575066	hsa-miR-8485	HITS-CLIP	27418678
MIRT575066	hsa-miR-8485	HITS-CLIP	22927820
MIRT575066	hsa-miR-8485	HITS-CLIP	23313552
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT664409	hsa-miR-548c-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT620601	hsa-miR-3065-5p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT620601	hsa-miR-3065-5p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT565284	hsa-miR-4694-3p	PAR-CLIP	20371350
MIRT565283	hsa-miR-5583-3p	PAR-CLIP	20371350
MIRT565282	hsa-miR-8076	PAR-CLIP	20371350
MIRT565281	hsa-miR-3688-3p	PAR-CLIP	20371350
MIRT565280	hsa-miR-4698	PAR-CLIP	20371350
MIRT565279	hsa-miR-605-3p	PAR-CLIP	20371350
MIRT565278	hsa-miR-1468-3p	PAR-CLIP	20371350
MIRT565277	hsa-miR-4434	PAR-CLIP	20371350
MIRT565275	hsa-miR-4516	PAR-CLIP	20371350
MIRT565276	hsa-miR-5703	PAR-CLIP	20371350
MIRT565274	hsa-miR-3653-3p	PAR-CLIP	20371350
MIRT565273	hsa-miR-4531	PAR-CLIP	20371350
MIRT439412	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT546261	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT439410	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT028037	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT546260	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT546259	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT546258	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT546257	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT546256	hsa-miR-3609	PAR-CLIP	21572407
MIRT546255	hsa-miR-548ah-5p	PAR-CLIP	21572407
MIRT546254	hsa-miR-4796-3p	PAR-CLIP	21572407
MIRT546253	hsa-miR-3606-3p	PAR-CLIP	21572407
MIRT546252	hsa-miR-513a-3p	PAR-CLIP	21572407
MIRT546251	hsa-miR-513c-3p	PAR-CLIP	21572407
MIRT546250	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT546249	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT546248	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT546247	hsa-miR-217	PAR-CLIP	21572407
MIRT546245	hsa-miR-6807-3p	PAR-CLIP	21572407
MIRT546246	hsa-miR-5579-5p	PAR-CLIP	21572407
MIRT546244	hsa-miR-4729	PAR-CLIP	21572407
MIRT546243	hsa-miR-20a-3p	PAR-CLIP	21572407
MIRT546242	hsa-miR-4635	PAR-CLIP	21572407
MIRT546241	hsa-miR-584-5p	PAR-CLIP	21572407
MIRT439412	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT546261	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT439410	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT028037	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT546260	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT546259	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT546258	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT546257	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT546256	hsa-miR-3609	PAR-CLIP	21572407
MIRT546255	hsa-miR-548ah-5p	PAR-CLIP	21572407
MIRT546254	hsa-miR-4796-3p	PAR-CLIP	21572407
MIRT546253	hsa-miR-3606-3p	PAR-CLIP	21572407
MIRT546252	hsa-miR-513a-3p	PAR-CLIP	21572407
MIRT546251	hsa-miR-513c-3p	PAR-CLIP	21572407
MIRT546250	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT546249	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT546248	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT546247	hsa-miR-217	PAR-CLIP	21572407
MIRT546245	hsa-miR-6807-3p	PAR-CLIP	21572407
MIRT546246	hsa-miR-5579-5p	PAR-CLIP	21572407
MIRT546244	hsa-miR-4729	PAR-CLIP	21572407
MIRT546243	hsa-miR-20a-3p	PAR-CLIP	21572407
MIRT546242	hsa-miR-4635	PAR-CLIP	21572407
MIRT546241	hsa-miR-584-5p	PAR-CLIP	21572407
MIRT1443080	hsa-miR-106a	CLIP-seq
MIRT1443081	hsa-miR-106b	CLIP-seq
MIRT1443082	hsa-miR-17	CLIP-seq
MIRT1443083	hsa-miR-20a	CLIP-seq
MIRT1443084	hsa-miR-20b	CLIP-seq
MIRT1443085	hsa-miR-219-2-3p	CLIP-seq
MIRT1443086	hsa-miR-224	CLIP-seq
MIRT1443087	hsa-miR-2964a-3p	CLIP-seq
MIRT1443088	hsa-miR-3133	CLIP-seq
MIRT1443089	hsa-miR-3159	CLIP-seq
MIRT1443090	hsa-miR-329	CLIP-seq
MIRT1443091	hsa-miR-33a	CLIP-seq
MIRT1443092	hsa-miR-33b	CLIP-seq
MIRT1443093	hsa-miR-3647-3p	CLIP-seq
MIRT1443094	hsa-miR-3653	CLIP-seq
MIRT1443095	hsa-miR-3658	CLIP-seq
MIRT740224	hsa-miR-3925-3p	CLIP-seq
MIRT1443096	hsa-miR-3973	CLIP-seq
MIRT1443097	hsa-miR-3978	CLIP-seq
MIRT1443098	hsa-miR-4252	CLIP-seq
MIRT1443099	hsa-miR-4311	CLIP-seq
MIRT1443100	hsa-miR-4428	CLIP-seq
MIRT1443101	hsa-miR-4452	CLIP-seq
MIRT1443102	hsa-miR-4457	CLIP-seq
MIRT1443103	hsa-miR-4511	CLIP-seq
MIRT1443104	hsa-miR-4528	CLIP-seq
MIRT740222	hsa-miR-4690-3p	CLIP-seq
MIRT1443105	hsa-miR-513b	CLIP-seq
MIRT740225	hsa-miR-515-5p	CLIP-seq
MIRT1443106	hsa-miR-519a	CLIP-seq
MIRT1443107	hsa-miR-519d	CLIP-seq
MIRT1443108	hsa-miR-520g	CLIP-seq
MIRT1443109	hsa-miR-520h	CLIP-seq
MIRT1443110	hsa-miR-548ah	CLIP-seq
MIRT1443111	hsa-miR-548u	CLIP-seq
MIRT740226	hsa-miR-579	CLIP-seq
MIRT1443112	hsa-miR-584	CLIP-seq
MIRT740223	hsa-miR-766	CLIP-seq
MIRT1443113	hsa-miR-888	CLIP-seq
MIRT1443114	hsa-miR-93	CLIP-seq
MIRT1443080	hsa-miR-106a	CLIP-seq
MIRT1443081	hsa-miR-106b	CLIP-seq
MIRT2353613	hsa-miR-1179	CLIP-seq
MIRT2353614	hsa-miR-125a-3p	CLIP-seq
MIRT2353615	hsa-miR-1301	CLIP-seq
MIRT2353616	hsa-miR-147	CLIP-seq
MIRT1443082	hsa-miR-17	CLIP-seq
MIRT2353617	hsa-miR-1825	CLIP-seq
MIRT2353618	hsa-miR-197	CLIP-seq
MIRT2353619	hsa-miR-198	CLIP-seq
MIRT2353620	hsa-miR-199a-5p	CLIP-seq
MIRT2353621	hsa-miR-199b-5p	CLIP-seq
MIRT2353622	hsa-miR-205	CLIP-seq
MIRT1443083	hsa-miR-20a	CLIP-seq
MIRT1443084	hsa-miR-20b	CLIP-seq
MIRT1443086	hsa-miR-224	CLIP-seq
MIRT2353623	hsa-miR-3128	CLIP-seq
MIRT2353624	hsa-miR-3153	CLIP-seq
MIRT1443090	hsa-miR-329	CLIP-seq
MIRT1443094	hsa-miR-3653	CLIP-seq
MIRT2353625	hsa-miR-3911	CLIP-seq
MIRT2353626	hsa-miR-412	CLIP-seq
MIRT1443098	hsa-miR-4252	CLIP-seq
MIRT2353627	hsa-miR-4302	CLIP-seq
MIRT2353628	hsa-miR-4648	CLIP-seq
MIRT2353629	hsa-miR-4654	CLIP-seq
MIRT2353630	hsa-miR-4668-5p	CLIP-seq
MIRT2353631	hsa-miR-4670-3p	CLIP-seq
MIRT2353632	hsa-miR-4769-5p	CLIP-seq
MIRT2353633	hsa-miR-5047	CLIP-seq
MIRT1443106	hsa-miR-519a	CLIP-seq
MIRT1443107	hsa-miR-519d	CLIP-seq
MIRT2353634	hsa-miR-548aa	CLIP-seq
MIRT2353635	hsa-miR-570	CLIP-seq
MIRT2353636	hsa-miR-582-5p	CLIP-seq
MIRT2353637	hsa-miR-600	CLIP-seq
MIRT2353638	hsa-miR-602	CLIP-seq
MIRT2353639	hsa-miR-644	CLIP-seq
MIRT1443114	hsa-miR-93	CLIP-seq
MIRT2396121	hsa-miR-3910	CLIP-seq
MIRT2396122	hsa-miR-4493	CLIP-seq
MIRT2396123	hsa-miR-4762-3p	CLIP-seq
MIRT2462070	hsa-miR-103a	CLIP-seq
MIRT1443080	hsa-miR-106a	CLIP-seq
MIRT1443081	hsa-miR-106b	CLIP-seq
MIRT2462071	hsa-miR-107	CLIP-seq
MIRT1443082	hsa-miR-17	CLIP-seq
MIRT1443083	hsa-miR-20a	CLIP-seq
MIRT1443084	hsa-miR-20b	CLIP-seq
MIRT1443090	hsa-miR-329	CLIP-seq
MIRT2462072	hsa-miR-3944-5p	CLIP-seq
MIRT1443106	hsa-miR-519a	CLIP-seq
MIRT1443107	hsa-miR-519d	CLIP-seq
MIRT1443108	hsa-miR-520g	CLIP-seq
MIRT1443109	hsa-miR-520h	CLIP-seq
MIRT1443114	hsa-miR-93	CLIP-seq
MIRT2462070	hsa-miR-103a	CLIP-seq
MIRT1443080	hsa-miR-106a	CLIP-seq
MIRT1443081	hsa-miR-106b	CLIP-seq
MIRT2462071	hsa-miR-107	CLIP-seq
MIRT2647791	hsa-miR-1185	CLIP-seq
MIRT2647792	hsa-miR-1224-5p	CLIP-seq
MIRT2647793	hsa-miR-1297	CLIP-seq
MIRT2647794	hsa-miR-135a	CLIP-seq
MIRT2647795	hsa-miR-135b	CLIP-seq
MIRT1443082	hsa-miR-17	CLIP-seq
MIRT1443083	hsa-miR-20a	CLIP-seq
MIRT1443084	hsa-miR-20b	CLIP-seq
MIRT2647796	hsa-miR-26a	CLIP-seq
MIRT2647797	hsa-miR-26b	CLIP-seq
MIRT2647798	hsa-miR-3121-3p	CLIP-seq
MIRT2647799	hsa-miR-3136-3p	CLIP-seq
MIRT2647800	hsa-miR-3167	CLIP-seq
MIRT2647801	hsa-miR-3180-5p	CLIP-seq
MIRT2647802	hsa-miR-3605-5p	CLIP-seq
MIRT2647803	hsa-miR-3679-5p	CLIP-seq
MIRT2647804	hsa-miR-3908	CLIP-seq
MIRT2647805	hsa-miR-3915	CLIP-seq
MIRT2462072	hsa-miR-3944-5p	CLIP-seq
MIRT2647806	hsa-miR-4465	CLIP-seq
MIRT2353631	hsa-miR-4670-3p	CLIP-seq
MIRT2647807	hsa-miR-4689	CLIP-seq
MIRT2647808	hsa-miR-4762-5p	CLIP-seq
MIRT2647809	hsa-miR-4773	CLIP-seq
MIRT1443106	hsa-miR-519a	CLIP-seq
MIRT1443107	hsa-miR-519d	CLIP-seq
MIRT2647810	hsa-miR-520a-5p	CLIP-seq
MIRT1443108	hsa-miR-520g	CLIP-seq
MIRT1443109	hsa-miR-520h	CLIP-seq
MIRT2647811	hsa-miR-525-5p	CLIP-seq
MIRT2647812	hsa-miR-548p	CLIP-seq
MIRT2647813	hsa-miR-663b	CLIP-seq
MIRT2647814	hsa-miR-876-5p	CLIP-seq
MIRT2647815	hsa-miR-9	CLIP-seq
MIRT1443114	hsa-miR-93	CLIP-seq
MIRT2462070	hsa-miR-103a	CLIP-seq
MIRT1443080	hsa-miR-106a	CLIP-seq
MIRT1443081	hsa-miR-106b	CLIP-seq
MIRT2462071	hsa-miR-107	CLIP-seq
MIRT2647791	hsa-miR-1185	CLIP-seq
MIRT2647792	hsa-miR-1224-5p	CLIP-seq
MIRT2647793	hsa-miR-1297	CLIP-seq
MIRT2647794	hsa-miR-135a	CLIP-seq
MIRT2647795	hsa-miR-135b	CLIP-seq
MIRT1443082	hsa-miR-17	CLIP-seq
MIRT1443083	hsa-miR-20a	CLIP-seq
MIRT1443084	hsa-miR-20b	CLIP-seq
MIRT2647796	hsa-miR-26a	CLIP-seq
MIRT2647797	hsa-miR-26b	CLIP-seq
MIRT2647798	hsa-miR-3121-3p	CLIP-seq
MIRT2647799	hsa-miR-3136-3p	CLIP-seq
MIRT2647800	hsa-miR-3167	CLIP-seq
MIRT2647801	hsa-miR-3180-5p	CLIP-seq
MIRT2647802	hsa-miR-3605-5p	CLIP-seq
MIRT2647803	hsa-miR-3679-5p	CLIP-seq
MIRT2647804	hsa-miR-3908	CLIP-seq
MIRT2647805	hsa-miR-3915	CLIP-seq
MIRT2462072	hsa-miR-3944-5p	CLIP-seq
MIRT2647806	hsa-miR-4465	CLIP-seq
MIRT2353631	hsa-miR-4670-3p	CLIP-seq
MIRT2647807	hsa-miR-4689	CLIP-seq
MIRT2647808	hsa-miR-4762-5p	CLIP-seq
MIRT2647809	hsa-miR-4773	CLIP-seq
MIRT1443106	hsa-miR-519a	CLIP-seq
MIRT1443107	hsa-miR-519d	CLIP-seq
MIRT2647810	hsa-miR-520a-5p	CLIP-seq
MIRT1443108	hsa-miR-520g	CLIP-seq
MIRT1443109	hsa-miR-520h	CLIP-seq
MIRT2647811	hsa-miR-525-5p	CLIP-seq
MIRT2647812	hsa-miR-548p	CLIP-seq
MIRT2647813	hsa-miR-663b	CLIP-seq
MIRT2647814	hsa-miR-876-5p	CLIP-seq
MIRT2647815	hsa-miR-9	CLIP-seq
MIRT1443114	hsa-miR-93	CLIP-seq

Transcription factors

Show/Hide all(1)

Transcription factor	Regulation	Reference
VDR	Activation	12520529

Show/Hide all(46)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001783	Process	B cell apoptotic process	IEA
GO:0001783	Process	B cell apoptotic process	ISS
GO:0002250	Process	Adaptive immune response	IBA
GO:0002250	Process	Adaptive immune response	IEA
GO:0002250	Process	Adaptive immune response	ISS
GO:0002376	Process	Immune system process	IEA
GO:0005515	Function	Protein binding	IPI	23559013, 32296183
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA	19654028
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	ISS
GO:0005886	Component	Plasma membrane	TAS
GO:0006915	Process	Apoptotic process	IEA
GO:0006915	Process	Apoptotic process	IMP	22761420
GO:0006959	Process	Humoral immune response	IBA
GO:0006959	Process	Humoral immune response	IEA
GO:0006959	Process	Humoral immune response	ISS
GO:0007165	Process	Signal transduction	IEA
GO:0007413	Process	Axonal fasciculation	IEA
GO:0016020	Component	Membrane	IEA
GO:0030889	Process	Negative regulation of B cell proliferation	IBA
GO:0030889	Process	Negative regulation of B cell proliferation	IEA
GO:0030889	Process	Negative regulation of B cell proliferation	ISS
GO:0031642	Process	Negative regulation of myelination	IBA
GO:0031642	Process	Negative regulation of myelination	IMP	21725297
GO:0032693	Process	Negative regulation of interleukin-10 production	IEA
GO:0032693	Process	Negative regulation of interleukin-10 production	ISS
GO:0032696	Process	Negative regulation of interleukin-13 production	IEA
GO:0032696	Process	Negative regulation of interleukin-13 production	ISS
GO:0032714	Process	Negative regulation of interleukin-5 production	IEA
GO:0032714	Process	Negative regulation of interleukin-5 production	ISS
GO:0042130	Process	Negative regulation of T cell proliferation	IBA
GO:0042130	Process	Negative regulation of T cell proliferation	IEA
GO:0042130	Process	Negative regulation of T cell proliferation	ISS
GO:0042552	Process	Myelination	IEA
GO:0042552	Process	Myelination	ISS
GO:0048713	Process	Regulation of oligodendrocyte differentiation	IEA
GO:0048713	Process	Regulation of oligodendrocyte differentiation	ISS
GO:0050852	Process	T cell receptor signaling pathway	IEA
GO:0050852	Process	T cell receptor signaling pathway	ISS
GO:0051402	Process	Neuron apoptotic process	IBA
GO:0051402	Process	Neuron apoptotic process	IEA
GO:0071356	Process	Cellular response to tumor necrosis factor	IDA	19654028
GO:0097252	Process	Oligodendrocyte apoptotic process	IBA
GO:0097252	Process	Oligodendrocyte apoptotic process	IEA
GO:0097252	Process	Oligodendrocyte apoptotic process	ISS

MIM	HGNC	e!Ensembl
605732	13469	ENSG00000146072

Protein

UniProt ID

O75509

Protein name

Tumor necrosis factor receptor superfamily member 21 (Death receptor 6) (CD antigen CD358)

Protein function

Promotes apoptosis, possibly via a pathway that involves the activation of NF-kappa-B. Can also promote apoptosis mediated by BAX and by the release of cytochrome c from the mitochondria into the cytoplasm. Trophic-factor deprivation triggers th

PDB

2DBH , 3QO4 , 3U3P , 3U3Q , 3U3S , 3U3T , 3U3V

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00020	TNFR_c6	51 → 88	TNFR/NGFR cysteine-rich region	Domain
PF00020	TNFR_c6	91 → 131	TNFR/NGFR cysteine-rich region	Domain
PF00020	TNFR_c6	171 → 211	TNFR/NGFR cysteine-rich region	Domain
PF00531	Death	417 → 498	Death domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Detected in fetal spinal cord and in brain neurons, with higher levels in brain from Alzheimer disease patients (at protein level). Highly expressed in heart, brain, placenta, pancreas, lymph node, thymus and prostate. Detected at lowe

Sequence

MGTSPSSSTALASCSRIARRATATMIAGSLLLLGFLSTTTAQPEQKASNLIGTYRHVDRA
TGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEK
LPCAALTDRECTCPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVP
SSVMKCKAYTDCLSQNLVVIKPGTKETDNVCGTLPSFSSSTSPSPGTAIFPRPEHMETHE
VPSSTYVPKGMNSTESNSSASVRPKVLSSIQEGTVPDNTSSARGKEDVNKTLPNLQVVNH
QQGPHHRHILKLLPSMEATGGEKSSTPIKGPKRGHPRQNLHKHFDINEHLPWMIVLFLLL
VLVVIVVCSIRKSSRTLKKGPRQDPSAIVEKAGLKKSMTPTQNREKWIYYCNGHGIDILK
LVAAQVGSQWKDIYQFLCNASEREVAAFSNGYTADHERAYAALQHWTIRGPEASLAQLIS
ALRQHRRNDVVEKIRGLMEDTTQLETDKLALPMSPSPLSPSPIPSPNAKLENSALLTVEP
SPQDKNKGFFVDESEPLLRCDSTSSGSSALSRNGSFITKEKKDTVLRQVRLDPCDLQPIF
DDMLHFLNPEELRVIEEIPQAEDKLDRLFEIIGVKSQEASQTLLDSVYSHLPDLL

Sequence length

655

Interactions

View interactions

	KEGG		Reactome
	Cytokine-cytokine receptor interaction		PPARA activates gene expression

Show/Hide Unknown Diseases (2)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Ischemic Stroke	Ischemic stroke	N/A	N/A	GWAS
Panic Disorder	Panic disorder	N/A	N/A	GWAS

Show/Hide Text Mining Associations (44)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenocarcinoma	Associate	34724890
Adenocarcinoma of Lung	Stimulate	40109864
Alopecia Areata	Associate	16417220
Arthritis Juvenile	Associate	10513798
Arthritis Rheumatoid	Associate	10765920, 37510374
Arthritis Rheumatoid	Inhibit	11247876, 6428222, 7788148
Biliary Atresia	Associate	9149338
Breast Neoplasms	Associate	40332226
Carcinoma Squamous Cell	Associate	35593591
CD8 Deficiency Familial	Associate	7972086
Dental Caries	Associate	9824493
Diabetes Mellitus Type 1	Associate	3456197
GATA2 Deficiency	Associate	19965620
Genital Neoplasms Female	Associate	25113253
Glaucoma	Associate	7742275
Glioma	Associate	22802048
Gliosarcoma	Associate	22567163
Hepatitis Alcoholic	Associate	40649881
Hepatitis C	Stimulate	28743875
HTLV I Infections	Associate	7972086
Hypertension	Inhibit	7742275
Inflammation	Associate	28348459
Leukemia Biphenotypic Acute	Associate	34101758
Lung Neoplasms	Associate	40109864
Lymphoma T Cell	Associate	28148900
Multiple Sclerosis Relapsing Remitting	Associate	15834022
Neoplasm Metastasis	Associate	36807122
Neoplasms	Associate	25113253, 40109864, 9714541
Neoplasms	Inhibit	33430890
Neuroinflammatory Diseases	Associate	36631443
Optic Nerve Diseases	Inhibit	7742275
Osteosarcoma	Associate	36807122
Ovarian Neoplasms	Associate	22567163, 25113253
Pemphigus	Associate	10417627, 8426112
Periodontitis	Associate	35154475
Renal Insufficiency Chronic	Associate	37510374
Retinitis	Inhibit	7742275
Sarcoidosis	Associate	7742275
Sarcoma	Stimulate	22567163
Sarcoma Synovial	Stimulate	22567163
Severe Acute Respiratory Syndrome	Associate	32778874
Stomach Neoplasms	Associate	39702278
Stress Disorders Post Traumatic	Associate	36631443
Thyroiditis Autoimmune	Associate	3456197

TNFRSF21 (TNF receptor superfamily member 21)