SLC39A1 (solute carrier family 39 member 1)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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27173 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Solute carrier family 39 member 1 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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SLC39A1 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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ZIP1, ZIRTL |
Chromosome
Chromosome number
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1 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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1q21.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the zinc-iron permease family. The encoded protein is localized to the cell membrane and acts as a zinc uptake transporter. This gene has been linked to prostate cancer, breast cancer, and Alzheimer`s disease. Alternative spl |
miRNA
miRNA information provided by mirtarbase database.
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Transcription factors | ||||||||||
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q9NY26 | ||||||||||
Protein name | Zinc transporter ZIP1 (Solute carrier family 39 member 1) (Zinc-iron-regulated transporter-like) (Zrt- and Irt-like protein 1) (ZIP-1) (hZIP1) | ||||||||||
Protein function | Transporter for the divalent cation Zn(2+). Mediates the influx of Zn(2+) into cells from extracellular space (PubMed:11301334, PubMed:12888280, PubMed:16844077). Functions as the major importer of zinc from circulating blood plasma into prostat | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Ubiquitous (PubMed:10610721, PubMed:11301334). Expressed in most adult and fetal tissues including the epidermis. {ECO:0000269|PubMed:10610721, ECO:0000269|PubMed:11301334}. | ||||||||||
Sequence |
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Sequence length | 324 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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