SLC39A1 (solute carrier family 39 member 1)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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27173 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Solute carrier family 39 member 1 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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SLC39A1 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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ZIP1, ZIRTL |
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Chromosome
Chromosome number
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1 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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1q21.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the zinc-iron permease family. The encoded protein is localized to the cell membrane and acts as a zinc uptake transporter. This gene has been linked to prostate cancer, breast cancer, and Alzheimer`s disease. Alternative spl |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q9NY26 | ||||||||||
| Protein name | Zinc transporter ZIP1 (Solute carrier family 39 member 1) (Zinc-iron-regulated transporter-like) (Zrt- and Irt-like protein 1) (ZIP-1) (hZIP1) | ||||||||||
| Protein function | Transporter for the divalent cation Zn(2+). Mediates the influx of Zn(2+) into cells from extracellular space (PubMed:11301334, PubMed:12888280, PubMed:16844077). Functions as the major importer of zinc from circulating blood plasma into prostat | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Ubiquitous (PubMed:10610721, PubMed:11301334). Expressed in most adult and fetal tissues including the epidermis. {ECO:0000269|PubMed:10610721, ECO:0000269|PubMed:11301334}. | ||||||||||
| Sequence |
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| Sequence length | 324 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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