PALD1 (phosphatase domain containing paladin 1)

Gene
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
27143
Gene name Gene Name - the full gene name approved by the HGNC.
Phosphatase domain containing paladin 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
PALD1
Synonyms (NCBI Gene) Gene synonyms aliases
KIAA1274, PALD
Chromosome Chromosome number
10
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
10q22.1
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(58)
miRTarBase ID miRNA Experiments Reference
MIRT020931 hsa-miR-155-5p Other 18262046
MIRT020931 hsa-miR-155-5p Reporter assay;Other 20584899
MIRT052627 hsa-let-7a-5p CLASH 23622248
MIRT052051 hsa-let-7b-5p CLASH 23622248
MIRT048127 hsa-miR-197-3p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(5)
GO ID Ontology Definition Evidence Reference
GO:0004725 Function Protein tyrosine phosphatase activity IBA 21873635
GO:0005515 Function Protein binding IPI 21903422
GO:0005737 Component Cytoplasm IBA 21873635
GO:0005829 Component Cytosol IDA 22354871
GO:0035335 Process Peptidyl-tyrosine dephosphorylation IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
614656 23530 ENSG00000107719
Protein
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Q9ULE6
Protein name Paladin
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF14566 PTPlike_phytase 161 → 330 Domain
PF14566 PTPlike_phytase 545 → 679 Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in endothelial cells, and in certain larger vessels, in mural cells. In the brain, possibly expressed in microglia. Expressed in peripheral blood mononuclear cells (at protein level). {ECO:0000269|PubMed:22354871}.
Sequence 
MGTTASTAQQTVSAGTPFEGLQGSGTMDSRHSVSIHSFQSTSLHNSKAKSIIPNKVAPVV
ITYNCKEEFQIHDELLKAHYTLGRLSDNTPEHYLVQGRYFLVRDVTEKMDVLGTVGSCGA
PNFRQVQGGLTVFGMGQPSLSGFRRVLQKLQKDGHRECVIFCVREEPVLFLRADEDFVSY
TPRDKQNLHENLQGLGPGVRVESLELAIRKEIHDFAQLSENTYHVYHNTEDLWGEPHAVA
IHGEDDLHVTEEVYKRPLFLQPTYRYHRLPLPEQGSPLEAQLDAFVSVLRETPSLLQLRD
AHGPPPALVFSCQMGVGRTNLGMVLGTLILLHRSGTTSQPEAAPTQAKPLPMEQFQVIQS
FLRMVPQGRRMVEEVDRAITACAELHDLKEVVLENQKKLEGIRPESPAQGSGSRHSVWQR
ALWSLERYFYLILFNYYLHEQYPLAFALSFSRWLCAHPELYRLPVTLSSAGPVAPRDLIA
RGSLREDDLVSPDALSTVREMDVANFRRVPRMPIYGTAQPSAKALGSILAYLTDAKRRLR
KVVWVSLREEAVLECDGHTYSLRWPGPPVAPDQLETLEAQLKAHLSEPPPGKEGPLTYRF
QTCLTMQEVFSQHRRACPGLTYHRIPMPDFCAPREEDFDQLLEALRAALSKDPGTGFVFS
CLSGQGRTTTAMVVAVLAFWHIQGFPEVGEEELVSVPDAKFTKGEFQVVMKVVQLLPDGH
RVKKEVDAALDTVSETMTPMHYHLREIIICTYRQAKAAKEAQEMRRLQLRSLQYLERYVC
LILFNAYLHLEKADSWQRPFSTWMQEVASKAGIYEILNELGFPELESGEDQPFSRLRYRW
QEQSCSLEPSAPEDLL
Sequence length 856
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide Causal Diseases (1)
Causal
Disease term Disease name dbSNP ID References
Diabetes mellitus Diabetes Mellitus, Non-Insulin-Dependent rs587776515, rs61730328, rs606231121, rs606231122, rs79020217, rs77625743, rs78378398, rs606231123, rs1362648752, rs104893649, rs80356624, rs80356616, rs80356625, rs80356611, rs104894237
View all (293 more)		 30130595
Show/Hide Unknown Diseases (2)
Unknown
Disease term Disease name Evidence References Source
Diabetes Diabetes GWAS
Carpal Tunnel Syndrome Carpal Tunnel Syndrome GWAS
Show/Hide Text Mining Associations (3)
Associations from Text Mining
Disease Name Relationship Type References
Carcinoma Pancreatic Ductal Associate 34313325
Lymphoma Large B Cell Diffuse Associate 26311899
Subarachnoid Hemorrhage Associate 32450902