Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
27131
Gene name Gene Name - the full gene name approved by the HGNC.
Sorting nexin 5
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
SNX5
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
20
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
20p11.23
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein functions in endosomal sorting, the phosphoi
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT027465 hsa-miR-98-5p Microarray 19088304
MIRT039538 hsa-miR-652-3p CLASH 23622248
MIRT498068 hsa-miR-454-3p PAR-CLIP 20371350
MIRT498067 hsa-miR-301b-3p PAR-CLIP 20371350
MIRT498066 hsa-miR-3666 PAR-CLIP 20371350
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0001726 Component Ruffle IEA
GO:0001891 Component Phagocytic cup IEA
GO:0005515 Function Protein binding IPI 19619496, 23085988, 25416956, 25588945, 28514442
GO:0005768 Component Endosome IBA 21873635
GO:0005829 Component Cytosol IDA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
605937 14969 ENSG00000089006
Protein
UniProt ID Q9Y5X3
Protein name Sorting nexin-5
Protein function Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) (PubMed:15561769). Acts in part as component of t
PDB 1SYS , 5TGH , 5TGI , 5TGJ , 5WY2 , 6N5X , 6N5Y , 6N5Z , 8A1G , 8ABQ , 8AFZ
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00787 PX 55 169 PX domain Domain
PF09325 Vps5 179 398 Vps5 C terminal like Domain
Sequence
Sequence length 404
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  Endocytosis   Golgi Associated Vesicle Biogenesis
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Gastric cancer Hereditary Diffuse Gastric Cancer rs137854571, rs63751108, rs34612342, rs121908383, rs121909144, rs121909775, rs121909219, rs121909223, rs63750871, rs80359530, rs121964873, rs121913530, rs606231203, rs121918505, rs587776802
View all (244 more)
21364753
Associations from Text Mining
Disease Name Relationship Type References
Glioma Associate 33982667
Squamous Cell Carcinoma of Head and Neck Associate 36528556
Stomach Neoplasms Stimulate 35715463
Stomach Neoplasms Associate 35831348