Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	27113
Gene name Gene Name - the full gene name approved by the HGNC.	BCL2 binding component 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	BBC3
Synonyms (NCBI Gene) Gene synonyms aliases	JFY-1, JFY1, PUMA
Chromosome Chromosome number	19
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	19q13.32
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It

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miRTarBase ID	miRNA	Experiments	Reference
MIRT004500	hsa-miR-483-3p	qRT-PCR, Luciferase reporter assay, Western blot, Northern blot	20388800
MIRT003367	hsa-miR-221-3p	Immunohistochemistry, In situ hybridization, Luciferase reporter assay, Northern blot, Western blot	20813046
MIRT005369	hsa-miR-222-3p	Immunohistochemistry, In situ hybridization, Luciferase reporter assay, Northern blot, Western blot	20813046
MIRT005915	hsa-miR-125b-5p	Luciferase reporter assay, qRT-PCR, Western blot	20886540
MIRT006683	hsa-miR-296-5p	Luciferase reporter assay, qRT-PCR, Western blot	21633093
MIRT003367	hsa-miR-221-3p	Luciferase reporter assay	21042732
MIRT005369	hsa-miR-222-3p	Luciferase reporter assay	21042732
MIRT016253	hsa-miR-504-5p	qRT-PCR	20542001
MIRT003367	hsa-miR-221-3p	Reporter assay;Microarray	20018759
MIRT003367	hsa-miR-221-3p	Luciferase reporter assay, qRT-PCR, Western blot	22075712
MIRT003367	hsa-miR-221-3p	qRT-PCR, Western blot, Reporter assay	22075712
MIRT005369	hsa-miR-222-3p	qRT-PCR, Western blot, Reporter assay	22075712
MIRT438653	hsa-miR-149-5p	Immunofluorescence, Luciferase reporter assay, Northern blot, qRT-PCR, Western blot	23873935
MIRT438653	hsa-miR-149-5p	Immunofluorescence, Luciferase reporter assay, Northern blot, qRT-PCR, Western blot	23873935
MIRT005369	hsa-miR-222-3p	Immunofluorescence, Luciferase reporter assay, qRT-PCR, Western blot	24452416
MIRT438653	hsa-miR-149-5p	Immunofluorescence, Luciferase reporter assay, Northern blot, qRT-PCR, Western blot	23873935
MIRT438653	hsa-miR-149-5p	Immunofluorescence, Luciferase reporter assay, Northern blot, qRT-PCR, Western blot	23873935
MIRT005369	hsa-miR-222-3p	Immunofluorescence, Luciferase reporter assay, qRT-PCR, Western blot	24452416
MIRT481013	hsa-miR-6088	PAR-CLIP	24398324
MIRT481012	hsa-miR-143-3p	PAR-CLIP	24398324
MIRT481010	hsa-miR-4770	PAR-CLIP	24398324
MIRT481011	hsa-miR-4324	PAR-CLIP	24398324
MIRT480971	hsa-miR-544b	PAR-CLIP	24398324
MIRT481009	hsa-miR-3124-3p	PAR-CLIP	24398324
MIRT481008	hsa-miR-4708-5p	PAR-CLIP	24398324
MIRT481007	hsa-miR-1273f	PAR-CLIP	24398324
MIRT481005	hsa-miR-6820-5p	PAR-CLIP	24398324
MIRT481003	hsa-miR-541-3p	PAR-CLIP	24398324
MIRT481002	hsa-miR-654-5p	PAR-CLIP	24398324
MIRT481001	hsa-miR-92a-2-5p	PAR-CLIP	24398324
MIRT481000	hsa-miR-6769a-5p	PAR-CLIP	24398324
MIRT480999	hsa-miR-6769b-5p	PAR-CLIP	24398324
MIRT480998	hsa-miR-323a-5p	PAR-CLIP	24398324
MIRT480997	hsa-miR-876-3p	PAR-CLIP	24398324
MIRT480996	hsa-miR-378a-5p	PAR-CLIP	24398324
MIRT480995	hsa-miR-1200	PAR-CLIP	24398324
MIRT480994	hsa-miR-1228-5p	PAR-CLIP	24398324
MIRT480993	hsa-miR-3074-5p	PAR-CLIP	24398324
MIRT480992	hsa-miR-7152-5p	PAR-CLIP	24398324
MIRT480990	hsa-miR-5586-3p	PAR-CLIP	23592263
MIRT480988	hsa-miR-759	PAR-CLIP	23592263
MIRT480987	hsa-miR-1252-5p	PAR-CLIP	23592263
MIRT480986	hsa-miR-3663-3p	PAR-CLIP	23592263
MIRT480967	hsa-miR-4755-3p	PAR-CLIP	23592263
MIRT480982	hsa-miR-29a-3p	PAR-CLIP	23592263
MIRT480981	hsa-miR-29c-3p	PAR-CLIP	23592263
MIRT005614	hsa-miR-29b-3p	PAR-CLIP	23592263
MIRT480980	hsa-miR-6753-5p	PAR-CLIP	23592263
MIRT480979	hsa-miR-4779	PAR-CLIP	23592263
MIRT480978	hsa-miR-4733-3p	PAR-CLIP	23592263
MIRT480977	hsa-miR-4459	PAR-CLIP	23592263
MIRT480976	hsa-miR-665	PAR-CLIP	23592263
MIRT480975	hsa-miR-6840-3p	PAR-CLIP	23592263
MIRT480974	hsa-miR-1915-3p	PAR-CLIP	23592263
MIRT480973	hsa-miR-6764-5p	PAR-CLIP	23592263
MIRT480972	hsa-miR-4726-3p	PAR-CLIP	23592263
MIRT480971	hsa-miR-544b	PAR-CLIP	23592263
MIRT480969	hsa-miR-4649-3p	PAR-CLIP	23592263
MIRT480970	hsa-miR-5008-5p	PAR-CLIP	23592263
MIRT480968	hsa-miR-6089	PAR-CLIP	23592263
MIRT480967	hsa-miR-4755-3p	PAR-CLIP	23592263
MIRT480966	hsa-miR-6828-5p	PAR-CLIP	23592263
MIRT480965	hsa-miR-765	PAR-CLIP	23592263
MIRT480963	hsa-miR-4271	PAR-CLIP	23592263
MIRT480962	hsa-miR-4725-3p	PAR-CLIP	23592263
MIRT480961	hsa-miR-6780b-5p	PAR-CLIP	23592263
MIRT480960	hsa-miR-625-5p	PAR-CLIP	23592263
MIRT480959	hsa-miR-6795-5p	PAR-CLIP	23592263
MIRT480958	hsa-miR-6887-5p	PAR-CLIP	23592263
MIRT481013	hsa-miR-6088	PAR-CLIP	23592263
MIRT481012	hsa-miR-143-3p	PAR-CLIP	23592263
MIRT481010	hsa-miR-4770	PAR-CLIP	23592263
MIRT481011	hsa-miR-4324	PAR-CLIP	23592263
MIRT480971	hsa-miR-544b	PAR-CLIP	23592263
MIRT481009	hsa-miR-3124-3p	PAR-CLIP	23592263
MIRT481008	hsa-miR-4708-5p	PAR-CLIP	23592263
MIRT481007	hsa-miR-1273f	PAR-CLIP	23592263
MIRT481005	hsa-miR-6820-5p	PAR-CLIP	23592263
MIRT481003	hsa-miR-541-3p	PAR-CLIP	23592263
MIRT481002	hsa-miR-654-5p	PAR-CLIP	23592263
MIRT481001	hsa-miR-92a-2-5p	PAR-CLIP	23592263
MIRT481000	hsa-miR-6769a-5p	PAR-CLIP	23592263
MIRT480999	hsa-miR-6769b-5p	PAR-CLIP	23592263
MIRT480998	hsa-miR-323a-5p	PAR-CLIP	23592263
MIRT480997	hsa-miR-876-3p	PAR-CLIP	23592263
MIRT480996	hsa-miR-378a-5p	PAR-CLIP	23592263
MIRT480995	hsa-miR-1200	PAR-CLIP	23592263
MIRT480994	hsa-miR-1228-5p	PAR-CLIP	23592263
MIRT480993	hsa-miR-3074-5p	PAR-CLIP	23592263
MIRT480992	hsa-miR-7152-5p	PAR-CLIP	23592263
MIRT481013	hsa-miR-6088	PAR-CLIP	23592263
MIRT481012	hsa-miR-143-3p	PAR-CLIP	23592263
MIRT481010	hsa-miR-4770	PAR-CLIP	23592263
MIRT481011	hsa-miR-4324	PAR-CLIP	23592263
MIRT481009	hsa-miR-3124-3p	PAR-CLIP	23592263
MIRT481008	hsa-miR-4708-5p	PAR-CLIP	23592263
MIRT481007	hsa-miR-1273f	PAR-CLIP	23592263
MIRT481006	hsa-miR-6087	PAR-CLIP	23592263
MIRT481005	hsa-miR-6820-5p	PAR-CLIP	23592263
MIRT481004	hsa-miR-4767	PAR-CLIP	23592263
MIRT481003	hsa-miR-541-3p	PAR-CLIP	23592263
MIRT481002	hsa-miR-654-5p	PAR-CLIP	23592263
MIRT481001	hsa-miR-92a-2-5p	PAR-CLIP	23592263
MIRT481000	hsa-miR-6769a-5p	PAR-CLIP	23592263
MIRT480999	hsa-miR-6769b-5p	PAR-CLIP	23592263
MIRT480998	hsa-miR-323a-5p	PAR-CLIP	23592263
MIRT480997	hsa-miR-876-3p	PAR-CLIP	23592263
MIRT480996	hsa-miR-378a-5p	PAR-CLIP	23592263
MIRT480995	hsa-miR-1200	PAR-CLIP	23592263
MIRT480994	hsa-miR-1228-5p	PAR-CLIP	23592263
MIRT480993	hsa-miR-3074-5p	PAR-CLIP	23592263
MIRT480992	hsa-miR-7152-5p	PAR-CLIP	23592263
MIRT480991	hsa-miR-4523	PAR-CLIP	23592263
MIRT480990	hsa-miR-5586-3p	PAR-CLIP	23592263
MIRT480989	hsa-miR-3943	PAR-CLIP	23592263
MIRT480988	hsa-miR-759	PAR-CLIP	23592263
MIRT480987	hsa-miR-1252-5p	PAR-CLIP	23592263
MIRT480986	hsa-miR-3663-3p	PAR-CLIP	23592263
MIRT480985	hsa-miR-1225-3p	PAR-CLIP	23592263
MIRT480984	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT480983	hsa-miR-4784	PAR-CLIP	23592263
MIRT480970	hsa-miR-5008-5p	PAR-CLIP	23592263
MIRT480968	hsa-miR-6089	PAR-CLIP	23592263
MIRT480967	hsa-miR-4755-3p	PAR-CLIP	23592263
MIRT480982	hsa-miR-29a-3p	PAR-CLIP	23592263
MIRT480981	hsa-miR-29c-3p	PAR-CLIP	23592263
MIRT005614	hsa-miR-29b-3p	PAR-CLIP	23592263
MIRT480980	hsa-miR-6753-5p	PAR-CLIP	23592263
MIRT480979	hsa-miR-4779	PAR-CLIP	23592263
MIRT480978	hsa-miR-4733-3p	PAR-CLIP	23592263
MIRT480977	hsa-miR-4459	PAR-CLIP	23592263
MIRT480976	hsa-miR-665	PAR-CLIP	23592263
MIRT480975	hsa-miR-6840-3p	PAR-CLIP	23592263
MIRT480974	hsa-miR-1915-3p	PAR-CLIP	23592263
MIRT480973	hsa-miR-6764-5p	PAR-CLIP	23592263
MIRT480972	hsa-miR-4726-3p	PAR-CLIP	23592263
MIRT480971	hsa-miR-544b	PAR-CLIP	23592263
MIRT480969	hsa-miR-4649-3p	PAR-CLIP	23592263
MIRT480970	hsa-miR-5008-5p	PAR-CLIP	23592263
MIRT480968	hsa-miR-6089	PAR-CLIP	23592263
MIRT480967	hsa-miR-4755-3p	PAR-CLIP	23592263
MIRT480966	hsa-miR-6828-5p	PAR-CLIP	23592263
MIRT480965	hsa-miR-765	PAR-CLIP	23592263
MIRT480964	hsa-miR-2861	PAR-CLIP	23592263
MIRT480963	hsa-miR-4271	PAR-CLIP	23592263
MIRT480962	hsa-miR-4725-3p	PAR-CLIP	23592263
MIRT480961	hsa-miR-6780b-5p	PAR-CLIP	23592263
MIRT480960	hsa-miR-625-5p	PAR-CLIP	23592263
MIRT480959	hsa-miR-6795-5p	PAR-CLIP	23592263
MIRT480958	hsa-miR-6887-5p	PAR-CLIP	23592263
MIRT004500	hsa-miR-483-3p	Microarray, qRT-PCR, Western blot	27120784
MIRT003367	hsa-miR-221-3p	Immunoblot, In situ hybridization, Luciferase reporter assay, Microarray, qRT-PCR, AGO2 binding RNA immunoprecipitation qRT-PCR,	26249174
MIRT003367	hsa-miR-221-3p	Immunoblot, In situ hybridization, Luciferase reporter assay, Microarray, qRT-PCR, AGO2 binding RNA immunoprecipitation qRT-PCR,	26249174
MIRT005369	hsa-miR-222-3p	Immunoblot, In situ hybridization, Luciferase reporter assay, Microarray, qRT-PCR, AGO2 binding RNA immunoprecipitation qRT-PCR,	26249174
MIRT005369	hsa-miR-222-3p	Immunoblot, In situ hybridization, Luciferase reporter assay, Microarray, qRT-PCR, AGO2 binding RNA immunoprecipitation qRT-PCR,	26249174
MIRT480994	hsa-miR-1228-5p	PAR-CLIP	26701625
MIRT480994	hsa-miR-1228-5p	PAR-CLIP	26701625
MIRT480994	hsa-miR-1228-5p	PAR-CLIP	26701625
MIRT480994	hsa-miR-1228-5p	PAR-CLIP	26701625
MIRT480994	hsa-miR-1228-5p	PAR-CLIP	26701625
MIRT480994	hsa-miR-1228-5p	PAR-CLIP	26701625
MIRT480994	hsa-miR-1228-5p	PAR-CLIP	26701625
MIRT480994	hsa-miR-1228-5p	PAR-CLIP	26701625
MIRT481007	hsa-miR-1273f	PAR-CLIP	26701625
MIRT481007	hsa-miR-1273f	PAR-CLIP	26701625
MIRT481012	hsa-miR-143-3p	PAR-CLIP	26701625
MIRT481012	hsa-miR-143-3p	PAR-CLIP	26701625
MIRT480998	hsa-miR-323a-5p	PAR-CLIP	26701625
MIRT480998	hsa-miR-323a-5p	PAR-CLIP	26701625
MIRT480998	hsa-miR-323a-5p	PAR-CLIP	26701625
MIRT480998	hsa-miR-323a-5p	PAR-CLIP	26701625
MIRT480998	hsa-miR-323a-5p	PAR-CLIP	26701625
MIRT480998	hsa-miR-323a-5p	PAR-CLIP	26701625
MIRT480998	hsa-miR-323a-5p	PAR-CLIP	26701625
MIRT480998	hsa-miR-323a-5p	PAR-CLIP	26701625
MIRT481008	hsa-miR-4708-5p	PAR-CLIP	26701625
MIRT481008	hsa-miR-4708-5p	PAR-CLIP	26701625
MIRT481004	hsa-miR-4767	PAR-CLIP	26701625
MIRT481004	hsa-miR-4767	PAR-CLIP	26701625
MIRT481004	hsa-miR-4767	PAR-CLIP	26701625
MIRT481004	hsa-miR-4767	PAR-CLIP	26701625
MIRT481004	hsa-miR-4767	PAR-CLIP	26701625
MIRT481004	hsa-miR-4767	PAR-CLIP	26701625
MIRT481004	hsa-miR-4767	PAR-CLIP	26701625
MIRT481004	hsa-miR-4767	PAR-CLIP	26701625
MIRT481010	hsa-miR-4770	PAR-CLIP	26701625
MIRT481010	hsa-miR-4770	PAR-CLIP	26701625
MIRT481003	hsa-miR-541-3p	PAR-CLIP	26701625
MIRT481003	hsa-miR-541-3p	PAR-CLIP	26701625
MIRT481003	hsa-miR-541-3p	PAR-CLIP	26701625
MIRT481003	hsa-miR-541-3p	PAR-CLIP	26701625
MIRT481003	hsa-miR-541-3p	PAR-CLIP	26701625
MIRT481003	hsa-miR-541-3p	PAR-CLIP	26701625
MIRT481003	hsa-miR-541-3p	PAR-CLIP	26701625
MIRT481003	hsa-miR-541-3p	PAR-CLIP	26701625
MIRT481006	hsa-miR-6087	PAR-CLIP	26701625
MIRT481006	hsa-miR-6087	PAR-CLIP	26701625
MIRT481006	hsa-miR-6087	PAR-CLIP	26701625
MIRT481006	hsa-miR-6087	PAR-CLIP	26701625
MIRT481006	hsa-miR-6087	PAR-CLIP	26701625
MIRT481006	hsa-miR-6087	PAR-CLIP	26701625
MIRT481006	hsa-miR-6087	PAR-CLIP	26701625
MIRT481006	hsa-miR-6087	PAR-CLIP	26701625
MIRT481013	hsa-miR-6088	PAR-CLIP	26701625
MIRT481013	hsa-miR-6088	PAR-CLIP	26701625
MIRT481002	hsa-miR-654-5p	PAR-CLIP	26701625
MIRT481002	hsa-miR-654-5p	PAR-CLIP	26701625
MIRT481002	hsa-miR-654-5p	PAR-CLIP	26701625
MIRT481002	hsa-miR-654-5p	PAR-CLIP	26701625
MIRT481002	hsa-miR-654-5p	PAR-CLIP	26701625
MIRT481002	hsa-miR-654-5p	PAR-CLIP	26701625
MIRT481002	hsa-miR-654-5p	PAR-CLIP	26701625
MIRT481002	hsa-miR-654-5p	PAR-CLIP	26701625
MIRT481000	hsa-miR-6769a-5p	PAR-CLIP	26701625
MIRT481000	hsa-miR-6769a-5p	PAR-CLIP	26701625
MIRT481000	hsa-miR-6769a-5p	PAR-CLIP	26701625
MIRT481000	hsa-miR-6769a-5p	PAR-CLIP	26701625
MIRT481000	hsa-miR-6769a-5p	PAR-CLIP	26701625
MIRT481000	hsa-miR-6769a-5p	PAR-CLIP	26701625
MIRT481000	hsa-miR-6769a-5p	PAR-CLIP	26701625
MIRT481000	hsa-miR-6769a-5p	PAR-CLIP	26701625
MIRT480999	hsa-miR-6769b-5p	PAR-CLIP	26701625
MIRT480999	hsa-miR-6769b-5p	PAR-CLIP	26701625
MIRT480999	hsa-miR-6769b-5p	PAR-CLIP	26701625
MIRT480999	hsa-miR-6769b-5p	PAR-CLIP	26701625
MIRT480999	hsa-miR-6769b-5p	PAR-CLIP	26701625
MIRT480999	hsa-miR-6769b-5p	PAR-CLIP	26701625
MIRT480999	hsa-miR-6769b-5p	PAR-CLIP	26701625
MIRT480999	hsa-miR-6769b-5p	PAR-CLIP	26701625
MIRT481005	hsa-miR-6820-5p	PAR-CLIP	26701625
MIRT481005	hsa-miR-6820-5p	PAR-CLIP	26701625
MIRT481005	hsa-miR-6820-5p	PAR-CLIP	26701625
MIRT481005	hsa-miR-6820-5p	PAR-CLIP	26701625
MIRT481005	hsa-miR-6820-5p	PAR-CLIP	26701625
MIRT481005	hsa-miR-6820-5p	PAR-CLIP	26701625
MIRT481005	hsa-miR-6820-5p	PAR-CLIP	26701625
MIRT481005	hsa-miR-6820-5p	PAR-CLIP	26701625
MIRT480997	hsa-miR-876-3p	PAR-CLIP	26701625
MIRT480997	hsa-miR-876-3p	PAR-CLIP	26701625
MIRT480997	hsa-miR-876-3p	PAR-CLIP	26701625
MIRT480997	hsa-miR-876-3p	PAR-CLIP	26701625
MIRT480997	hsa-miR-876-3p	PAR-CLIP	26701625
MIRT480997	hsa-miR-876-3p	PAR-CLIP	26701625
MIRT480997	hsa-miR-876-3p	PAR-CLIP	26701625
MIRT480997	hsa-miR-876-3p	PAR-CLIP	26701625
MIRT481001	hsa-miR-92a-2-5p	PAR-CLIP	26701625
MIRT481001	hsa-miR-92a-2-5p	PAR-CLIP	26701625
MIRT481001	hsa-miR-92a-2-5p	PAR-CLIP	26701625
MIRT481001	hsa-miR-92a-2-5p	PAR-CLIP	26701625
MIRT481001	hsa-miR-92a-2-5p	PAR-CLIP	26701625
MIRT481001	hsa-miR-92a-2-5p	PAR-CLIP	26701625
MIRT481001	hsa-miR-92a-2-5p	PAR-CLIP	26701625
MIRT481001	hsa-miR-92a-2-5p	PAR-CLIP	26701625
MIRT003367	hsa-miR-221-3p	qRT-PCR	33336275
MIRT004500	hsa-miR-483-3p	Luciferase reporter assay, Western blotting, Northern blotting, qRT-PCR, in vivo gain/loss-of-function experiments	20388800
MIRT004500	hsa-miR-483-3p	Luciferase reporter assay, Western blotting, Microarray, in vitro cullelar assays, qRT-PCR	21859927
MIRT481013	hsa-miR-6088	PAR-CLIP	24398324
MIRT481012	hsa-miR-143-3p	PAR-CLIP	24398324
MIRT481010	hsa-miR-4770	PAR-CLIP	24398324
MIRT481011	hsa-miR-4324	PAR-CLIP	24398324
MIRT480971	hsa-miR-544b	PAR-CLIP	24398324
MIRT481009	hsa-miR-3124-3p	PAR-CLIP	24398324
MIRT481008	hsa-miR-4708-5p	PAR-CLIP	24398324
MIRT481007	hsa-miR-1273f	PAR-CLIP	24398324
MIRT481005	hsa-miR-6820-5p	PAR-CLIP	24398324
MIRT481003	hsa-miR-541-3p	PAR-CLIP	24398324
MIRT481002	hsa-miR-654-5p	PAR-CLIP	24398324
MIRT481001	hsa-miR-92a-2-5p	PAR-CLIP	24398324
MIRT481000	hsa-miR-6769a-5p	PAR-CLIP	24398324
MIRT480999	hsa-miR-6769b-5p	PAR-CLIP	24398324
MIRT480998	hsa-miR-323a-5p	PAR-CLIP	24398324
MIRT480997	hsa-miR-876-3p	PAR-CLIP	24398324
MIRT480996	hsa-miR-378a-5p	PAR-CLIP	24398324
MIRT480995	hsa-miR-1200	PAR-CLIP	24398324
MIRT480994	hsa-miR-1228-5p	PAR-CLIP	24398324
MIRT480993	hsa-miR-3074-5p	PAR-CLIP	24398324
MIRT480992	hsa-miR-7152-5p	PAR-CLIP	24398324
MIRT480990	hsa-miR-5586-3p	PAR-CLIP	23592263
MIRT480988	hsa-miR-759	PAR-CLIP	23592263
MIRT480987	hsa-miR-1252-5p	PAR-CLIP	23592263
MIRT480986	hsa-miR-3663-3p	PAR-CLIP	23592263
MIRT480967	hsa-miR-4755-3p	PAR-CLIP	23592263
MIRT480982	hsa-miR-29a-3p	PAR-CLIP	23592263
MIRT480981	hsa-miR-29c-3p	PAR-CLIP	23592263
MIRT005614	hsa-miR-29b-3p	PAR-CLIP	23592263
MIRT480980	hsa-miR-6753-5p	PAR-CLIP	23592263
MIRT480979	hsa-miR-4779	PAR-CLIP	23592263
MIRT480978	hsa-miR-4733-3p	PAR-CLIP	23592263
MIRT480977	hsa-miR-4459	PAR-CLIP	23592263
MIRT480976	hsa-miR-665	PAR-CLIP	23592263
MIRT480975	hsa-miR-6840-3p	PAR-CLIP	23592263
MIRT480974	hsa-miR-1915-3p	PAR-CLIP	23592263
MIRT480973	hsa-miR-6764-5p	PAR-CLIP	23592263
MIRT480972	hsa-miR-4726-3p	PAR-CLIP	23592263
MIRT480971	hsa-miR-544b	PAR-CLIP	23592263
MIRT480969	hsa-miR-4649-3p	PAR-CLIP	23592263
MIRT480970	hsa-miR-5008-5p	PAR-CLIP	23592263
MIRT480968	hsa-miR-6089	PAR-CLIP	23592263
MIRT480967	hsa-miR-4755-3p	PAR-CLIP	23592263
MIRT480966	hsa-miR-6828-5p	PAR-CLIP	23592263
MIRT480965	hsa-miR-765	PAR-CLIP	23592263
MIRT480963	hsa-miR-4271	PAR-CLIP	23592263
MIRT480962	hsa-miR-4725-3p	PAR-CLIP	23592263
MIRT480961	hsa-miR-6780b-5p	PAR-CLIP	23592263
MIRT480960	hsa-miR-625-5p	PAR-CLIP	23592263
MIRT480959	hsa-miR-6795-5p	PAR-CLIP	23592263
MIRT480958	hsa-miR-6887-5p	PAR-CLIP	23592263
MIRT481013	hsa-miR-6088	PAR-CLIP	23592263
MIRT481012	hsa-miR-143-3p	PAR-CLIP	23592263
MIRT481010	hsa-miR-4770	PAR-CLIP	23592263
MIRT481011	hsa-miR-4324	PAR-CLIP	23592263
MIRT480971	hsa-miR-544b	PAR-CLIP	23592263
MIRT481009	hsa-miR-3124-3p	PAR-CLIP	23592263
MIRT481008	hsa-miR-4708-5p	PAR-CLIP	23592263
MIRT481007	hsa-miR-1273f	PAR-CLIP	23592263
MIRT481005	hsa-miR-6820-5p	PAR-CLIP	23592263
MIRT481003	hsa-miR-541-3p	PAR-CLIP	23592263
MIRT481002	hsa-miR-654-5p	PAR-CLIP	23592263
MIRT481001	hsa-miR-92a-2-5p	PAR-CLIP	23592263
MIRT481000	hsa-miR-6769a-5p	PAR-CLIP	23592263
MIRT480999	hsa-miR-6769b-5p	PAR-CLIP	23592263
MIRT480998	hsa-miR-323a-5p	PAR-CLIP	23592263
MIRT480997	hsa-miR-876-3p	PAR-CLIP	23592263
MIRT480996	hsa-miR-378a-5p	PAR-CLIP	23592263
MIRT480995	hsa-miR-1200	PAR-CLIP	23592263
MIRT480994	hsa-miR-1228-5p	PAR-CLIP	23592263
MIRT480993	hsa-miR-3074-5p	PAR-CLIP	23592263
MIRT480992	hsa-miR-7152-5p	PAR-CLIP	23592263
MIRT481013	hsa-miR-6088	PAR-CLIP	23592263
MIRT481012	hsa-miR-143-3p	PAR-CLIP	23592263
MIRT481010	hsa-miR-4770	PAR-CLIP	23592263
MIRT481011	hsa-miR-4324	PAR-CLIP	23592263
MIRT481009	hsa-miR-3124-3p	PAR-CLIP	23592263
MIRT481008	hsa-miR-4708-5p	PAR-CLIP	23592263
MIRT481007	hsa-miR-1273f	PAR-CLIP	23592263
MIRT481006	hsa-miR-6087	PAR-CLIP	23592263
MIRT481005	hsa-miR-6820-5p	PAR-CLIP	23592263
MIRT481004	hsa-miR-4767	PAR-CLIP	23592263
MIRT481003	hsa-miR-541-3p	PAR-CLIP	23592263
MIRT481002	hsa-miR-654-5p	PAR-CLIP	23592263
MIRT481001	hsa-miR-92a-2-5p	PAR-CLIP	23592263
MIRT481000	hsa-miR-6769a-5p	PAR-CLIP	23592263
MIRT480999	hsa-miR-6769b-5p	PAR-CLIP	23592263
MIRT480998	hsa-miR-323a-5p	PAR-CLIP	23592263
MIRT480997	hsa-miR-876-3p	PAR-CLIP	23592263
MIRT480996	hsa-miR-378a-5p	PAR-CLIP	23592263
MIRT480995	hsa-miR-1200	PAR-CLIP	23592263
MIRT480994	hsa-miR-1228-5p	PAR-CLIP	23592263
MIRT480993	hsa-miR-3074-5p	PAR-CLIP	23592263
MIRT480992	hsa-miR-7152-5p	PAR-CLIP	23592263
MIRT480991	hsa-miR-4523	PAR-CLIP	23592263
MIRT480990	hsa-miR-5586-3p	PAR-CLIP	23592263
MIRT480989	hsa-miR-3943	PAR-CLIP	23592263
MIRT480988	hsa-miR-759	PAR-CLIP	23592263
MIRT480987	hsa-miR-1252-5p	PAR-CLIP	23592263
MIRT480986	hsa-miR-3663-3p	PAR-CLIP	23592263
MIRT480985	hsa-miR-1225-3p	PAR-CLIP	23592263
MIRT480984	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT480983	hsa-miR-4784	PAR-CLIP	23592263
MIRT480970	hsa-miR-5008-5p	PAR-CLIP	23592263
MIRT480968	hsa-miR-6089	PAR-CLIP	23592263
MIRT480967	hsa-miR-4755-3p	PAR-CLIP	23592263
MIRT480982	hsa-miR-29a-3p	PAR-CLIP	23592263
MIRT480981	hsa-miR-29c-3p	PAR-CLIP	23592263
MIRT005614	hsa-miR-29b-3p	PAR-CLIP	23592263
MIRT480980	hsa-miR-6753-5p	PAR-CLIP	23592263
MIRT480979	hsa-miR-4779	PAR-CLIP	23592263
MIRT480978	hsa-miR-4733-3p	PAR-CLIP	23592263
MIRT480977	hsa-miR-4459	PAR-CLIP	23592263
MIRT480976	hsa-miR-665	PAR-CLIP	23592263
MIRT480975	hsa-miR-6840-3p	PAR-CLIP	23592263
MIRT480974	hsa-miR-1915-3p	PAR-CLIP	23592263
MIRT480973	hsa-miR-6764-5p	PAR-CLIP	23592263
MIRT480972	hsa-miR-4726-3p	PAR-CLIP	23592263
MIRT480971	hsa-miR-544b	PAR-CLIP	23592263
MIRT480969	hsa-miR-4649-3p	PAR-CLIP	23592263
MIRT480970	hsa-miR-5008-5p	PAR-CLIP	23592263
MIRT480968	hsa-miR-6089	PAR-CLIP	23592263
MIRT480967	hsa-miR-4755-3p	PAR-CLIP	23592263
MIRT480966	hsa-miR-6828-5p	PAR-CLIP	23592263
MIRT480965	hsa-miR-765	PAR-CLIP	23592263
MIRT480964	hsa-miR-2861	PAR-CLIP	23592263
MIRT480963	hsa-miR-4271	PAR-CLIP	23592263
MIRT480962	hsa-miR-4725-3p	PAR-CLIP	23592263
MIRT480961	hsa-miR-6780b-5p	PAR-CLIP	23592263
MIRT480960	hsa-miR-625-5p	PAR-CLIP	23592263
MIRT480959	hsa-miR-6795-5p	PAR-CLIP	23592263
MIRT480958	hsa-miR-6887-5p	PAR-CLIP	23592263
MIRT816632	hsa-miR-101	CLIP-seq
MIRT816633	hsa-miR-1184	CLIP-seq
MIRT816634	hsa-miR-1207-3p	CLIP-seq
MIRT816635	hsa-miR-122	CLIP-seq
MIRT816636	hsa-miR-1226	CLIP-seq
MIRT816637	hsa-miR-1289	CLIP-seq
MIRT816638	hsa-miR-1298	CLIP-seq
MIRT816639	hsa-miR-1301	CLIP-seq
MIRT816640	hsa-miR-139-5p	CLIP-seq
MIRT816641	hsa-miR-144	CLIP-seq
MIRT816642	hsa-miR-148a	CLIP-seq
MIRT816643	hsa-miR-148b	CLIP-seq
MIRT816644	hsa-miR-152	CLIP-seq
MIRT816645	hsa-miR-1587	CLIP-seq
MIRT816646	hsa-miR-1910	CLIP-seq
MIRT816647	hsa-miR-199a-5p	CLIP-seq
MIRT816648	hsa-miR-199b-5p	CLIP-seq
MIRT816649	hsa-miR-24	CLIP-seq
MIRT816650	hsa-miR-3120-3p	CLIP-seq
MIRT816651	hsa-miR-3135b	CLIP-seq
MIRT816652	hsa-miR-3605-3p	CLIP-seq
MIRT816653	hsa-miR-3652	CLIP-seq
MIRT816654	hsa-miR-378g	CLIP-seq
MIRT816655	hsa-miR-4283	CLIP-seq
MIRT816656	hsa-miR-4430	CLIP-seq
MIRT816657	hsa-miR-4433	CLIP-seq
MIRT816658	hsa-miR-4438	CLIP-seq
MIRT816659	hsa-miR-4489	CLIP-seq
MIRT816660	hsa-miR-4492	CLIP-seq
MIRT816661	hsa-miR-4498	CLIP-seq
MIRT816662	hsa-miR-4505	CLIP-seq
MIRT816663	hsa-miR-4656	CLIP-seq
MIRT816664	hsa-miR-4660	CLIP-seq
MIRT816665	hsa-miR-4663	CLIP-seq
MIRT816666	hsa-miR-4664-3p	CLIP-seq
MIRT816667	hsa-miR-4675	CLIP-seq
MIRT816668	hsa-miR-4697-3p	CLIP-seq
MIRT816669	hsa-miR-4728-3p	CLIP-seq
MIRT816670	hsa-miR-4731-5p	CLIP-seq
MIRT816671	hsa-miR-4741	CLIP-seq
MIRT816672	hsa-miR-4760-3p	CLIP-seq
MIRT816673	hsa-miR-503	CLIP-seq
MIRT816674	hsa-miR-5047	CLIP-seq
MIRT816675	hsa-miR-5095	CLIP-seq
MIRT816676	hsa-miR-597	CLIP-seq
MIRT816677	hsa-miR-600	CLIP-seq
MIRT816678	hsa-miR-604	CLIP-seq
MIRT816679	hsa-miR-634	CLIP-seq
MIRT816680	hsa-miR-647	CLIP-seq
MIRT816681	hsa-miR-664	CLIP-seq
MIRT816682	hsa-miR-711	CLIP-seq
MIRT816683	hsa-miR-762	CLIP-seq
MIRT816632	hsa-miR-101	CLIP-seq
MIRT816635	hsa-miR-122	CLIP-seq
MIRT816638	hsa-miR-1298	CLIP-seq
MIRT816640	hsa-miR-139-5p	CLIP-seq
MIRT816641	hsa-miR-144	CLIP-seq
MIRT816684	hsa-miR-1913	CLIP-seq
MIRT816650	hsa-miR-3120-3p	CLIP-seq
MIRT816651	hsa-miR-3135b	CLIP-seq
MIRT816685	hsa-miR-324-3p	CLIP-seq
MIRT816686	hsa-miR-3647-3p	CLIP-seq
MIRT816653	hsa-miR-3652	CLIP-seq
MIRT816655	hsa-miR-4283	CLIP-seq
MIRT816656	hsa-miR-4430	CLIP-seq
MIRT816659	hsa-miR-4489	CLIP-seq
MIRT816660	hsa-miR-4492	CLIP-seq
MIRT816661	hsa-miR-4498	CLIP-seq
MIRT816666	hsa-miR-4664-3p	CLIP-seq
MIRT816687	hsa-miR-4707-5p	CLIP-seq
MIRT816672	hsa-miR-4760-3p	CLIP-seq
MIRT816673	hsa-miR-503	CLIP-seq
MIRT816677	hsa-miR-600	CLIP-seq
MIRT816678	hsa-miR-604	CLIP-seq
MIRT816680	hsa-miR-647	CLIP-seq
MIRT816681	hsa-miR-664	CLIP-seq
MIRT816683	hsa-miR-762	CLIP-seq
MIRT1941519	hsa-miR-143	CLIP-seq
MIRT816649	hsa-miR-24	CLIP-seq
MIRT1941520	hsa-miR-4667-3p	CLIP-seq
MIRT1941521	hsa-miR-642a	CLIP-seq
MIRT816632	hsa-miR-101	CLIP-seq
MIRT2180259	hsa-miR-1236	CLIP-seq
MIRT816638	hsa-miR-1298	CLIP-seq
MIRT816640	hsa-miR-139-5p	CLIP-seq
MIRT1941519	hsa-miR-143	CLIP-seq
MIRT816641	hsa-miR-144	CLIP-seq
MIRT2180260	hsa-miR-1470	CLIP-seq
MIRT816649	hsa-miR-24	CLIP-seq
MIRT816650	hsa-miR-3120-3p	CLIP-seq
MIRT2180261	hsa-miR-323-5p	CLIP-seq
MIRT2180262	hsa-miR-3545-5p	CLIP-seq
MIRT816686	hsa-miR-3647-3p	CLIP-seq
MIRT816658	hsa-miR-4438	CLIP-seq
MIRT2180263	hsa-miR-4469	CLIP-seq
MIRT816662	hsa-miR-4505	CLIP-seq
MIRT2180264	hsa-miR-4529-5p	CLIP-seq
MIRT2180265	hsa-miR-4640-5p	CLIP-seq
MIRT816666	hsa-miR-4664-3p	CLIP-seq
MIRT1941520	hsa-miR-4667-3p	CLIP-seq
MIRT2180266	hsa-miR-4726-5p	CLIP-seq
MIRT816672	hsa-miR-4760-3p	CLIP-seq
MIRT816673	hsa-miR-503	CLIP-seq
MIRT816675	hsa-miR-5095	CLIP-seq
MIRT2180267	hsa-miR-541	CLIP-seq
MIRT816677	hsa-miR-600	CLIP-seq
MIRT1941521	hsa-miR-642a	CLIP-seq
MIRT816681	hsa-miR-664	CLIP-seq
MIRT816662	hsa-miR-4505	CLIP-seq
MIRT816637	hsa-miR-1289	CLIP-seq
MIRT2435635	hsa-miR-149	CLIP-seq
MIRT816662	hsa-miR-4505	CLIP-seq
MIRT2435636	hsa-miR-940	CLIP-seq

Transcription factors

Show/Hide all(8)

Transcription factor	Regulation	Reference
CTCF	Unknown	20818159
E2F1	Activation	17263886
ETV6	Activation	16828711
FOXO3	Unknown	21654193
TCF3	Repression	23684607
TP53	Activation	17280505
TP53	Unknown	11572983;15988033;18755897;22763818
TP73	Activation	17700533

Show/Hide all(52)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001836	Process	Release of cytochrome c from mitochondria	IBA
GO:0001836	Process	Release of cytochrome c from mitochondria	IDA	11463392
GO:0005515	Function	Protein binding	IPI	11463391, 11463392, 15694340, 16151013, 16608847, 16697956, 17177603, 17289999, 20153921, 20627101, 22516262, 26212789, 26431330, 28514442, 32296183
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IBA
GO:0005739	Component	Mitochondrion	IDA	11463391, 11463392
GO:0005739	Component	Mitochondrion	IEA
GO:0005739	Component	Mitochondrion	TAS	26212789
GO:0005741	Component	Mitochondrial outer membrane	TAS
GO:0005764	Component	Lysosome	IDA	26212789
GO:0005829	Component	Cytosol	TAS
GO:0006915	Process	Apoptotic process	IEA
GO:0006915	Process	Apoptotic process	IMP	26212789
GO:0006974	Process	DNA damage response	IEA
GO:0006974	Process	DNA damage response	ISS
GO:0008340	Process	Determination of adult lifespan	IEA
GO:0008340	Process	Determination of adult lifespan	ISS
GO:0031334	Process	Positive regulation of protein-containing complex assembly	IDA	21041309
GO:0034976	Process	Response to endoplasmic reticulum stress	IDA	22761832
GO:0034976	Process	Response to endoplasmic reticulum stress	IEA
GO:0042771	Process	Intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	IEA
GO:0043065	Process	Positive regulation of apoptotic process	IEA
GO:0043525	Process	Positive regulation of neuron apoptotic process	IEA
GO:0043525	Process	Positive regulation of neuron apoptotic process	ISS
GO:0044346	Process	Fibroblast apoptotic process	IEA
GO:0051117	Function	ATPase binding	IPI	26212789
GO:0070059	Process	Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	IBA
GO:0070059	Process	Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	IDA	16407291
GO:0070059	Process	Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	IEA
GO:0070059	Process	Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	ISS
GO:0070227	Process	Lymphocyte apoptotic process	IEA
GO:0070230	Process	Positive regulation of lymphocyte apoptotic process	IEA
GO:0070231	Process	T cell apoptotic process	IEA
GO:0070234	Process	Positive regulation of T cell apoptotic process	IEA
GO:0070245	Process	Positive regulation of thymocyte apoptotic process	IEA
GO:0070245	Process	Positive regulation of thymocyte apoptotic process	ISS
GO:0071456	Process	Cellular response to hypoxia	IEP	20810912
GO:0071479	Process	Cellular response to ionizing radiation	IEA
GO:0090200	Process	Positive regulation of release of cytochrome c from mitochondria	IBA
GO:0090200	Process	Positive regulation of release of cytochrome c from mitochondria	IEA
GO:0090200	Process	Positive regulation of release of cytochrome c from mitochondria	IGI	21041309
GO:0097190	Process	Apoptotic signaling pathway	IDA	11463392
GO:0097193	Process	Intrinsic apoptotic signaling pathway	IDA	17024184
GO:0097193	Process	Intrinsic apoptotic signaling pathway	IEA
GO:0097194	Process	Execution phase of apoptosis	IBA
GO:0097194	Process	Execution phase of apoptosis	IDA	11463391, 11463392
GO:1902237	Process	Positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	TAS	22013210
GO:1903749	Process	Positive regulation of establishment of protein localization to mitochondrion	IEA
GO:1903896	Process	Positive regulation of IRE1-mediated unfolded protein response	TAS	22013210
GO:2000271	Process	Positive regulation of fibroblast apoptotic process	IEA
GO:2001244	Process	Positive regulation of intrinsic apoptotic signaling pathway	IMP	17289999, 27031958
GO:2001244	Process	Positive regulation of intrinsic apoptotic signaling pathway	ISS

MIM	HGNC	e!Ensembl
605854	17868	ENSG00000105327

Protein

UniProt ID

Q96PG8

Protein name

Bcl-2-binding component 3, isoforms 3/4 (JFY-1) (p53 up-regulated modulator of apoptosis)

Protein function

[Isoform 3]: Does not affect cell growth.

Family and domains

Sequence

MKFGMGSAQACPCQVPRAASTTWVPCQICGPRERHGPRTPGGQLPGARRGPGPRRPAPLP
ARPPGALGSVLRPLRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAP
RPAPGRSSALALAGGAAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVGPGDRGPAAADGG
RPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRPVDVRDS
GGRPLPPPDTLASAGDFLCTM

Sequence length

261

UniProt ID

Q9BXH1

Protein name

Bcl-2-binding component 3, isoforms 1/2 (JFY-1) (p53 up-regulated modulator of apoptosis)

Protein function

Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis (PubMed:11463391, PubMed:23340338). Promotes partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53, releasing the bound p53/TP53 to induce apoptosis (PubM

PDB

2M04 , 4BPI , 4BPJ , 4BPK , 4HNJ , 5UUL , 6QFM , 6QG8 , 6TQP , 7DVD , 7P0S , 7P9W , 7QTX

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF15826	PUMA	2 → 193	Bcl-2-binding component 3, p53 upregulated modulator of apoptosis	Family

Tissue specificity

TISSUE SPECIFICITY: Ubiquitously expressed. {ECO:0000269|PubMed:11463391}.

Sequence

MARARQEGSSPEPVEGLARDGPRPFPLGRLVPSAVSCGLCEPGLAAAPAAPTLLPAAYLC
APTAPPAVTAALGGSRWPGGPRSRPRGPRPDGPQPSLSLAEQHLESPVPSAPGALAGGPT
QAAPGVRGEEEQWAREIGAQLRRMADDLNAQYERRRQEEQQRHRPSPWRVLYNLIMGLLP
LPRGHRAPEMEPN

Sequence length

193

Interactions

View interactions

	KEGG		Reactome
	Platinum drug resistance p53 signaling pathway Apoptosis Apoptosis - multiple species Hippo signaling pathway Huntington disease Measles Pathways in cancer Colorectal cancer		BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members Activation of PUMA and translocation to mitochondria TP53 Regulates Transcription of Genes Involved in Cytochrome C Release FOXO-mediated transcription of cell death genes

Show/Hide Unknown Diseases (1)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Alzheimer disease	Alzheimer's disease or family history of Alzheimer's disease	N/A	N/A	GWAS

Show/Hide Text Mining Associations (72)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenocarcinoma	Stimulate	35135489
Adrenocortical Carcinoma	Associate	21859927
Arthritis Rheumatoid	Associate	16447235
Arthritis Rheumatoid	Stimulate	40141133
Breast Neoplasms	Associate	15756011, 20431602, 24073403, 26273641, 28099441, 34587475
Breast Neoplasms	Stimulate	19934289
Burkitt Lymphoma	Associate	26431330, 28960205
Carcinoma	Associate	28692117
Carcinoma Adenoid Cystic	Associate	28277192
Carcinoma Hepatocellular	Associate	25635973, 29693134, 34123711
Carcinoma Mucoepidermoid	Associate	29363716
Carcinoma Non Small Cell Lung	Associate	22788963, 25895606, 30024623, 30556447, 32588752, 36200643, 37044023
Carcinoma Pancreatic Ductal	Associate	23321162, 25184537
Carcinoma Renal Cell	Associate	25499216
Carcinoma Renal Cell	Inhibit	28692117
Cell Transformation Neoplastic	Associate	26431330
Chromosomal Instability	Associate	18556456
Colonic Neoplasms	Associate	18794091
Colorectal Neoplasms	Associate	12574499, 15123817, 15262986, 16608847, 17263886, 17360476, 18367875, 18794091, 18811981, 19380879, 21855041, 22912816, 24610575, 26043078, 26631035, 36030982, 36508676 View all (2 more)
COVID 19	Stimulate	36443881
Death	Associate	18670645
Drug Related Side Effects and Adverse Reactions	Stimulate	16481741, 21686164, 27494845
Drug Related Side Effects and Adverse Reactions	Associate	20431602, 22990204, 25893985
Endometrial Neoplasms	Associate	18423823
Esophageal Neoplasms	Associate	16481741
Esophageal Squamous Cell Carcinoma	Associate	31638164, 33034274
Forebrain Defects	Stimulate	12913114
Glioblastoma	Associate	20153921, 37279651
Glioma	Associate	18670645
Glucagonoma	Associate	28921546
Head and Neck Neoplasms	Inhibit	23220852
Hyperoxia	Associate	18215742
Hypoxia	Stimulate	18670645
Hypoxia	Inhibit	34181359
Hypoxia Brain	Associate	18670645
Idiopathic Pulmonary Fibrosis	Associate	40022042
Infections	Associate	15452181
Keratoconus	Associate	36160033
Leukemia	Associate	18579560, 19737931, 25555870, 29179704
Leukemia Lymphocytic Chronic B Cell	Associate	19096009, 21205967, 28424416
Leukemia Myeloid Acute	Associate	23996484, 27249593, 29723246
Lung Neoplasms	Associate	24012673, 27780918, 27878984, 34388376, 36224313
Lupus Erythematosus Systemic	Associate	27492607
Lymphoma Follicular	Inhibit	24660851
Lymphoma Primary Effusion	Associate	31366879
Malformations of Cortical Development Group I	Associate	36431966
Melanoma	Associate	17263886, 19620789, 20357812, 25365078, 27689874
Microsatellite Instability	Associate	36508676
Mitochondrial Diseases	Associate	16127150, 19851330, 26043078, 36200643
Mitochondrial Diseases	Stimulate	28423586
Nasopharyngeal Carcinoma	Inhibit	18838543
Nasopharyngeal Neoplasms	Associate	26612445
Neoplasms	Associate	17263886, 17360476, 17510315, 18159231, 18367875, 18579560, 18794091, 22130069, 22788963, 22912816, 23220852, 24236056, 24610575, 26720344, 27058618 View all (7 more)
Neoplasms	Inhibit	21863213, 25184537, 25635973, 28921546, 40154596
Neuroblastoma	Associate	16091745, 21878749, 29959561, 31362335
Oropharyngeal Neoplasms	Associate	22086558
Osteosarcoma	Stimulate	14627843
Ovarian Neoplasms	Associate	21863213, 28423586, 32424251, 36122664
Pancreatic Neoplasms	Associate	21909380, 23321162
Pancreatitis	Associate	23321162
Pre Eclampsia	Associate	31477211
Prostatic Neoplasms	Associate	30577600
Sarcoma	Associate	36849535
Sarcoma Ewing	Associate	36849535
Sepsis	Associate	36443881
Silicosis	Associate	26576741
Squamous Cell Carcinoma of Head and Neck	Associate	16413463, 22086558, 23220852
Stomach Neoplasms	Associate	17149756, 18838543
Tetraploidy	Associate	18159231
Translocation Genetic	Associate	36849535
Urinary Bladder Neoplasms	Associate	30443191
Uterine Cervical Neoplasms	Associate	36431966

BBC3 (BCL2 binding component 3)