Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID	27071
Gene name	Dual adaptor of phosphotyrosine and 3-phosphoinositides 1
Gene symbol	DAPP1
Synonyms (NCBI Gene)	BAM32
Chromosome	4
Chromosome location	4q23

124

Show/Hide all (124)

miRTarBase ID	miRNA	Experiments
MIRT923202	hsa-miR-1200	CLIP-seq
MIRT923203	hsa-miR-129-5p	CLIP-seq
MIRT923204	hsa-miR-1302	CLIP-seq
MIRT923205	hsa-miR-184	CLIP-seq
MIRT923206	hsa-miR-1976	CLIP-seq
MIRT923207	hsa-miR-2052	CLIP-seq
MIRT923208	hsa-miR-3122	CLIP-seq
MIRT923209	hsa-miR-3149	CLIP-seq
MIRT923210	hsa-miR-3182	CLIP-seq
MIRT923211	hsa-miR-345	CLIP-seq
MIRT923212	hsa-miR-3664-5p	CLIP-seq
MIRT923213	hsa-miR-3913-5p	CLIP-seq
MIRT923214	hsa-miR-4279	CLIP-seq
MIRT923215	hsa-miR-4294	CLIP-seq
MIRT923216	hsa-miR-4298	CLIP-seq
MIRT923217	hsa-miR-4324	CLIP-seq
MIRT923218	hsa-miR-4438	CLIP-seq
MIRT923219	hsa-miR-4522	CLIP-seq
MIRT923220	hsa-miR-4532	CLIP-seq
MIRT923221	hsa-miR-4652-3p	CLIP-seq
MIRT923222	hsa-miR-4715-3p	CLIP-seq
MIRT740093	hsa-miR-4722-3p	CLIP-seq
MIRT923223	hsa-miR-4735-5p	CLIP-seq
MIRT923224	hsa-miR-4763-5p	CLIP-seq
MIRT923225	hsa-miR-4775	CLIP-seq
MIRT740094	hsa-miR-492	CLIP-seq
MIRT923226	hsa-miR-498	CLIP-seq
MIRT923227	hsa-miR-5095	CLIP-seq
MIRT740092	hsa-miR-513a-3p	CLIP-seq
MIRT923228	hsa-miR-520d-5p	CLIP-seq
MIRT923229	hsa-miR-524-5p	CLIP-seq
MIRT923230	hsa-miR-544b	CLIP-seq
MIRT923231	hsa-miR-550b	CLIP-seq
MIRT923232	hsa-miR-566	CLIP-seq
MIRT923233	hsa-miR-590-3p	CLIP-seq
MIRT1547860	hsa-miR-4420	CLIP-seq
MIRT1547861	hsa-miR-4772-3p	CLIP-seq
MIRT923202	hsa-miR-1200	CLIP-seq
MIRT923203	hsa-miR-129-5p	CLIP-seq
MIRT923206	hsa-miR-1976	CLIP-seq
MIRT923214	hsa-miR-4279	CLIP-seq
MIRT1973543	hsa-miR-4307	CLIP-seq
MIRT923217	hsa-miR-4324	CLIP-seq
MIRT1547860	hsa-miR-4420	CLIP-seq
MIRT923218	hsa-miR-4438	CLIP-seq
MIRT923220	hsa-miR-4532	CLIP-seq
MIRT740093	hsa-miR-4722-3p	CLIP-seq
MIRT1547861	hsa-miR-4772-3p	CLIP-seq
MIRT923226	hsa-miR-498	CLIP-seq
MIRT923227	hsa-miR-5095	CLIP-seq
MIRT923230	hsa-miR-544b	CLIP-seq
MIRT1973544	hsa-miR-659	CLIP-seq
MIRT923202	hsa-miR-1200	CLIP-seq
MIRT923206	hsa-miR-1976	CLIP-seq
MIRT923214	hsa-miR-4279	CLIP-seq
MIRT923217	hsa-miR-4324	CLIP-seq
MIRT1547860	hsa-miR-4420	CLIP-seq
MIRT923218	hsa-miR-4438	CLIP-seq
MIRT923220	hsa-miR-4532	CLIP-seq
MIRT740093	hsa-miR-4722-3p	CLIP-seq
MIRT1547861	hsa-miR-4772-3p	CLIP-seq
MIRT923226	hsa-miR-498	CLIP-seq
MIRT923227	hsa-miR-5095	CLIP-seq
MIRT923230	hsa-miR-544b	CLIP-seq
MIRT923202	hsa-miR-1200	CLIP-seq
MIRT923206	hsa-miR-1976	CLIP-seq
MIRT923214	hsa-miR-4279	CLIP-seq
MIRT923217	hsa-miR-4324	CLIP-seq
MIRT740093	hsa-miR-4722-3p	CLIP-seq
MIRT923226	hsa-miR-498	CLIP-seq
MIRT923230	hsa-miR-544b	CLIP-seq
MIRT923202	hsa-miR-1200	CLIP-seq
MIRT923206	hsa-miR-1976	CLIP-seq
MIRT923214	hsa-miR-4279	CLIP-seq
MIRT923217	hsa-miR-4324	CLIP-seq
MIRT923218	hsa-miR-4438	CLIP-seq
MIRT923220	hsa-miR-4532	CLIP-seq
MIRT740093	hsa-miR-4722-3p	CLIP-seq
MIRT923226	hsa-miR-498	CLIP-seq
MIRT923227	hsa-miR-5095	CLIP-seq
MIRT923230	hsa-miR-544b	CLIP-seq
MIRT923232	hsa-miR-566	CLIP-seq
MIRT923202	hsa-miR-1200	CLIP-seq
MIRT923206	hsa-miR-1976	CLIP-seq
MIRT923214	hsa-miR-4279	CLIP-seq
MIRT923217	hsa-miR-4324	CLIP-seq
MIRT923220	hsa-miR-4532	CLIP-seq
MIRT740093	hsa-miR-4722-3p	CLIP-seq
MIRT923226	hsa-miR-498	CLIP-seq
MIRT923230	hsa-miR-544b	CLIP-seq
MIRT923202	hsa-miR-1200	CLIP-seq
MIRT923206	hsa-miR-1976	CLIP-seq
MIRT923209	hsa-miR-3149	CLIP-seq
MIRT923214	hsa-miR-4279	CLIP-seq
MIRT923217	hsa-miR-4324	CLIP-seq
MIRT923218	hsa-miR-4438	CLIP-seq
MIRT923220	hsa-miR-4532	CLIP-seq
MIRT923222	hsa-miR-4715-3p	CLIP-seq
MIRT740093	hsa-miR-4722-3p	CLIP-seq
MIRT923223	hsa-miR-4735-5p	CLIP-seq
MIRT923224	hsa-miR-4763-5p	CLIP-seq
MIRT923225	hsa-miR-4775	CLIP-seq
MIRT923226	hsa-miR-498	CLIP-seq
MIRT923227	hsa-miR-5095	CLIP-seq
MIRT923230	hsa-miR-544b	CLIP-seq
MIRT923232	hsa-miR-566	CLIP-seq
MIRT923233	hsa-miR-590-3p	CLIP-seq
MIRT923202	hsa-miR-1200	CLIP-seq
MIRT923206	hsa-miR-1976	CLIP-seq
MIRT923209	hsa-miR-3149	CLIP-seq
MIRT923214	hsa-miR-4279	CLIP-seq
MIRT923217	hsa-miR-4324	CLIP-seq
MIRT923218	hsa-miR-4438	CLIP-seq
MIRT923220	hsa-miR-4532	CLIP-seq
MIRT923222	hsa-miR-4715-3p	CLIP-seq
MIRT740093	hsa-miR-4722-3p	CLIP-seq
MIRT923223	hsa-miR-4735-5p	CLIP-seq
MIRT923224	hsa-miR-4763-5p	CLIP-seq
MIRT923225	hsa-miR-4775	CLIP-seq
MIRT923226	hsa-miR-498	CLIP-seq
MIRT923227	hsa-miR-5095	CLIP-seq
MIRT923230	hsa-miR-544b	CLIP-seq
MIRT923232	hsa-miR-566	CLIP-seq
MIRT923233	hsa-miR-590-3p	CLIP-seq

Show/Hide all (14)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25814554, 32296183, 32814053
GO:0005543	Function	Phospholipid binding	IBA
GO:0005543	Function	Phospholipid binding	NAS	10432293
GO:0005547	Function	Phosphatidylinositol-3,4,5-trisphosphate binding	IDA	11001876
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA	17823121
GO:0005886	Component	Plasma membrane	TAS
GO:0006470	Process	Protein dephosphorylation	NAS	10432293
GO:0007165	Process	Signal transduction	TAS	10432293
GO:0016020	Component	Membrane	IEA
GO:0043325	Function	Phosphatidylinositol-3,4-bisphosphate binding	IBA
GO:0043325	Function	Phosphatidylinositol-3,4-bisphosphate binding	IDA	11001876, 17823121

MIM	HGNC	e!Ensembl
605768	16500	ENSG00000070190

Q9UN19

Protein name

Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (hDAPP1) (B lymphocyte adapter protein Bam32) (B-cell adapter molecule of 32 kDa)

Protein function

May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.

PDB

1FAO , 1FB8

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00017	SH2	35 → 109	SH2 domain	Domain
PF00169	PH	165 → 259	PH domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells. {ECO:0000269|PubMed:10432293}.

Sequence

MGRAELLEGKMSTQDPSDLWSRSDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLL
RDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKFGFNEFSSLKDFVKHFANQPLIGSETG
TLMVLKHPYPRKVEEPSIYESVRVHTAMQTGRTEDDLVPTAPSLGTKEGYLTKQGGLVKT
WKTRWFTLHRNELKYFKDQMSPEPIRILDLTECSAVQFDYSQERVNCFCLVFPFRTFYLC
AKTGVEADEWIKILRWKLSQIRKQLNQGEGTIRSRSFIFK

Sequence length

280

Interactions

View interactions

	KEGG		Reactome
	B cell receptor signaling pathway		Antigen activates B Cell Receptor (BCR) leading to generation of second messengers

DAPP1 (dual adaptor of phosphotyrosine and 3-phosphoinositides 1)