GH2 (growth hormone 2)

Gene Gene information from NCBI Gene database.
Gene Transcription factors Gene ontology Other IDs Protein Pathways
Entrez ID 2689
Gene name Growth hormone 2
Gene symbol GH2
Synonyms (NCBI Gene)
GH-VGHB2GHLGHVhGH-V
Chromosome 17
Chromosome location 17q23.3
Summary The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they
Transcription factors Transcription factors information provided by TRRUST V2 database.
3
Gene Transcription factors Gene ontology Other IDs Protein Pathways
Show/Hide all (3)
Transcription factor Regulation Reference
FOXF1 Activation 16772323
POU1F1 Activation 7608249
SP1 Unknown 1427648
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
18
Gene Transcription factors Gene ontology Other IDs Protein Pathways
Show/Hide all (18)
GO ID Ontology Definition Evidence Reference
GO:0005131 Function Growth hormone receptor binding IBA
GO:0005131 Function Growth hormone receptor binding IEA
GO:0005179 Function Hormone activity IBA
GO:0005179 Function Hormone activity IEA
GO:0005179 Function Hormone activity TAS 8943276
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene Transcription factors Gene ontology Other IDs Protein Pathways
MIM HGNC e!Ensembl
139240 4262 ENSG00000136487
Protein Protein information from UniProt database.
Gene Transcription factors Gene ontology Other IDs Protein Pathways
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P01242
Protein name Growth hormone variant (GH-V) (Growth hormone 2) (Placenta-specific growth hormone)
Protein function Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino aci
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00103 Hormone_1 9 → 215 Somatotropin hormone family Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in the placenta.
Sequence
Sequence length 217
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene Transcription factors Gene ontology Other IDs Protein Pathways
  KEGG  Reactome
  Cytokine-cytokine receptor interaction
Neuroactive ligand-receptor interaction
Hormone signaling
PI3K-Akt signaling pathway
JAK-STAT signaling pathway
Growth hormone synthesis, secretion and action 		  Prolactin receptor signaling
Growth hormone receptor signaling