GH2 (growth hormone 2)

Gene
Gene Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
2689
Gene name Gene Name - the full gene name approved by the HGNC.
Growth hormone 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
GH2
Synonyms (NCBI Gene) Gene synonyms aliases
GH-V, GHB2, GHL, GHV, hGH-V
Chromosome Chromosome number
17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
17q23.3
Summary Summary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they
Transcription factors
Gene Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(3)
Transcription factor Regulation Reference
FOXF1 Activation 16772323
POU1F1 Activation 7608249
SP1 Unknown 1427648
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(13)
GO ID Ontology Definition Evidence Reference
GO:0005131 Function Growth hormone receptor binding IBA 21873635
GO:0005179 Function Hormone activity IBA 21873635
GO:0005576 Component Extracellular region TAS
GO:0005615 Component Extracellular space IBA 21873635
GO:0008083 Function Growth factor activity IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
139240 4262 ENSG00000136487
Protein
Gene Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID P01242
Protein name Growth hormone variant (GH-V) (Growth hormone 2) (Placenta-specific growth hormone)
Protein function Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino aci
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00103 Hormone_1 9 → 215 Somatotropin hormone family Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in the placenta.
Sequence
Sequence length 217
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
  KEGG   Reactome
  Cytokine-cytokine receptor interaction
Neuroactive ligand-receptor interaction
Hormone signaling
PI3K-Akt signaling pathway
JAK-STAT signaling pathway
Growth hormone synthesis, secretion and action 		  Prolactin receptor signaling
Growth hormone receptor signaling
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide Unknown Diseases (1)
Unknown
Disease term Disease name Evidence References Source
Diabetes Diabetes GWAS
Show/Hide Text Mining Associations (3)
Associations from Text Mining
Disease Name Relationship Type References
Diabetes Gestational Associate 22387044
Pre Eclampsia Inhibit 22387044
Stomach Neoplasms Associate 37350375