AMELY (amelogenin Y-linked)

Gene
Gene miRNA Gene ontology Other IDs Protein
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
266
Gene name Gene Name - the full gene name approved by the HGNC.
Amelogenin Y-linked
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
AMELY
Synonyms (NCBI Gene) Gene synonyms aliases
AMGL, AMGY
Chromosome Chromosome number
Y
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
Yp11.2
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in a related gene on chromosome X cause X-linked amelogenesis imperfecta. [provi
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein
Show/Hide all(12)
miRTarBase ID miRNA Experiments Reference
MIRT017665 hsa-miR-335-5p Microarray 18185580
MIRT779735 hsa-miR-125a-5p CLIP-seq
MIRT779736 hsa-miR-125b CLIP-seq
MIRT779737 hsa-miR-4319 CLIP-seq
MIRT779738 hsa-miR-4732-3p CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein
Show/Hide all(8)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32296183
GO:0005576 Component Extracellular region IEA
GO:0030345 Function Structural constituent of tooth enamel IBA
GO:0030345 Function Structural constituent of tooth enamel IDA 1734713
GO:0031012 Component Extracellular matrix IBA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein
MIM HGNC e!Ensembl
410000 462 ENSG00000099721
Protein
Gene miRNA Gene ontology Other IDs Protein
UniProt ID Q99218
Protein name Amelogenin, Y isoform
Protein function Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02948 Amelogenin 21 → 206 Family
Sequence
Sequence length 206
Interactions View interactions
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