TSPAN16 (tetraspanin 16)

Gene
Gene Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
26526
Gene name Gene Name - the full gene name approved by the HGNC.
Tetraspanin 16
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
TSPAN16
Synonyms (NCBI Gene) Gene synonyms aliases
TM-8, TM4-B, TM4SF16
Chromosome Chromosome number
19
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
19p13.2
Summary Summary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Protein Associated diseases
Show/Hide all(4)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 33961781
GO:0005886 Component Plasma membrane IBA
GO:0016020 Component Membrane IEA
GO:0016020 Component Membrane TAS 10500248
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
617580 30725 ENSG00000130167
Protein
Gene Gene ontology Other IDs Protein Associated diseases
UniProt ID Q9UKR8
Protein name Tetraspanin-16 (Tspan-16) (Tetraspanin TM4-B) (Transmembrane 4 superfamily member 16)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00335 Tetraspanin 11 → 235 Tetraspanin family Family
Tissue specificity TISSUE SPECIFICITY: Broadly expressed in most human tissues and cell lines including neural and bone marrow derived tissues.
Sequence
Sequence length 245
Interactions View interactions
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Gene Gene ontology Other IDs Protein Associated diseases
Show/Hide Unknown Diseases (3)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Breast Cancer Breast cancer N/A N/A GWAS
Glioblastoma Glioblastoma N/A N/A GWAS
Schizophrenia Schizophrenia N/A N/A GWAS