Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
26519
Gene name Gene Name - the full gene name approved by the HGNC.
Translocase of inner mitochondrial membrane 10
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
TIMM10
Synonyms (NCBI Gene) Gene synonyms aliases
TIM10, TIM10A, TIMM10A
Chromosome Chromosome number
11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
11q12.1
Summary Summary of gene provided in NCBI Entrez Gene.
The mitochondrial protein encoded by this gene belongs to a family of evolutionarily conserved proteins that are organized in heterooligomeric complexes in the mitochondrial intermembrane space. These proteins mediate the import and insertion of hydrophob
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT028579 hsa-miR-30a-5p Proteomics 18668040
MIRT029571 hsa-miR-26b-5p Microarray 19088304
MIRT046101 hsa-miR-125b-5p CLASH 23622248
MIRT553660 hsa-miR-362-3p HITS-CLIP 21572407
MIRT553659 hsa-miR-329-3p HITS-CLIP 21572407
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 14726512, 30021884, 32296183
GO:0005739 Component Mitochondrion IDA
GO:0005743 Component Mitochondrial inner membrane IBA 21873635
GO:0005743 Component Mitochondrial inner membrane IDA 14726512
GO:0005743 Component Mitochondrial inner membrane TAS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
602251 11814 ENSG00000134809
Protein
UniProt ID P62072
Protein name Mitochondrial import inner membrane translocase subunit Tim10
Protein function Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex
PDB 2BSK , 7CGP
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02953 zf-Tim10_DDP 7 71 Tim10/DDP family zinc finger Domain
Tissue specificity TISSUE SPECIFICITY: Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle. {ECO:0000269|PubMed:10552927, ECO:0000269|PubMed:10611480}.
Sequence
Sequence length 90
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Mitochondrial protein import
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Lung adenocarcinoma Adenocarcinoma of lung (disorder) rs28934576, rs121913530, rs397516975, rs587776805, rs121913469, rs121913364, rs121913351, rs121913366, rs397516896, rs397516977, rs397516981, rs397517127, rs121913344, rs727504233, rs121913370
View all (5 more)
27602772
Rhabdomyosarcoma Rhabdomyosarcoma rs137854557, rs121909224, rs63751466, rs11540652, rs28934874, rs104894229, rs104894230, rs267606708, rs80357867, rs276174889, rs80359011, rs80358556, rs80359391, rs80357989, rs886037650
View all (19 more)
16669873
Associations from Text Mining
Disease Name Relationship Type References
HIV Infections Associate 28065665
Prostatic Neoplasms Associate 36901944
Tuberculosis Associate 28065665