Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	26507
Gene name Gene Name - the full gene name approved by the HGNC.	Cyclin and CBS domain divalent metal cation transport mediator 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	CNNM1
Synonyms (NCBI Gene) Gene synonyms aliases	ACDP1, CLP-1, SLC70A1
Chromosome Chromosome number	10
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	10q24.2
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the ancient conserved domain protein family. The encoded protein may bind copper. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

Show/Hide all(239)

miRTarBase ID	miRNA	Experiments
MIRT899915	hsa-miR-1237	CLIP-seq
MIRT899916	hsa-miR-1245	CLIP-seq
MIRT899917	hsa-miR-1248	CLIP-seq
MIRT899918	hsa-miR-125a-5p	CLIP-seq
MIRT899919	hsa-miR-125b	CLIP-seq
MIRT899920	hsa-miR-1276	CLIP-seq
MIRT899921	hsa-miR-129-5p	CLIP-seq
MIRT899922	hsa-miR-1297	CLIP-seq
MIRT899923	hsa-miR-132	CLIP-seq
MIRT899924	hsa-miR-146a	CLIP-seq
MIRT899925	hsa-miR-146b-5p	CLIP-seq
MIRT899926	hsa-miR-1915	CLIP-seq
MIRT899927	hsa-miR-197	CLIP-seq
MIRT899928	hsa-miR-212	CLIP-seq
MIRT899929	hsa-miR-26a	CLIP-seq
MIRT899930	hsa-miR-26b	CLIP-seq
MIRT899931	hsa-miR-3065-3p	CLIP-seq
MIRT899932	hsa-miR-3134	CLIP-seq
MIRT899933	hsa-miR-3160-5p	CLIP-seq
MIRT899934	hsa-miR-3170	CLIP-seq
MIRT899935	hsa-miR-3179	CLIP-seq
MIRT899936	hsa-miR-3182	CLIP-seq
MIRT899937	hsa-miR-3187-3p	CLIP-seq
MIRT899938	hsa-miR-3202	CLIP-seq
MIRT899939	hsa-miR-331-3p	CLIP-seq
MIRT899940	hsa-miR-342-5p	CLIP-seq
MIRT899941	hsa-miR-3653	CLIP-seq
MIRT899942	hsa-miR-3658	CLIP-seq
MIRT899943	hsa-miR-3663-5p	CLIP-seq
MIRT899944	hsa-miR-3689d	CLIP-seq
MIRT899945	hsa-miR-371-5p	CLIP-seq
MIRT899946	hsa-miR-371b-5p	CLIP-seq
MIRT899947	hsa-miR-383	CLIP-seq
MIRT899948	hsa-miR-4267	CLIP-seq
MIRT899949	hsa-miR-4291	CLIP-seq
MIRT899950	hsa-miR-4292	CLIP-seq
MIRT899951	hsa-miR-4303	CLIP-seq
MIRT899952	hsa-miR-4311	CLIP-seq
MIRT899953	hsa-miR-4319	CLIP-seq
MIRT899954	hsa-miR-4328	CLIP-seq
MIRT899955	hsa-miR-4329	CLIP-seq
MIRT899956	hsa-miR-4424	CLIP-seq
MIRT899957	hsa-miR-4435	CLIP-seq
MIRT899958	hsa-miR-4443	CLIP-seq
MIRT899959	hsa-miR-4465	CLIP-seq
MIRT899960	hsa-miR-4476	CLIP-seq
MIRT899961	hsa-miR-4509	CLIP-seq
MIRT899962	hsa-miR-4511	CLIP-seq
MIRT899963	hsa-miR-4529-5p	CLIP-seq
MIRT899964	hsa-miR-4534	CLIP-seq
MIRT899965	hsa-miR-4640-3p	CLIP-seq
MIRT899966	hsa-miR-4651	CLIP-seq
MIRT899967	hsa-miR-4652-3p	CLIP-seq
MIRT899968	hsa-miR-4664-5p	CLIP-seq
MIRT899969	hsa-miR-4682	CLIP-seq
MIRT899970	hsa-miR-4701-5p	CLIP-seq
MIRT899971	hsa-miR-4716-5p	CLIP-seq
MIRT899972	hsa-miR-4728-5p	CLIP-seq
MIRT899973	hsa-miR-4740-3p	CLIP-seq
MIRT899974	hsa-miR-4744	CLIP-seq
MIRT899975	hsa-miR-4755-3p	CLIP-seq
MIRT899976	hsa-miR-4761-5p	CLIP-seq
MIRT899977	hsa-miR-4772-3p	CLIP-seq
MIRT899978	hsa-miR-4778-5p	CLIP-seq
MIRT899979	hsa-miR-4781-3p	CLIP-seq
MIRT899980	hsa-miR-4785	CLIP-seq
MIRT899981	hsa-miR-5096	CLIP-seq
MIRT899982	hsa-miR-548b-3p	CLIP-seq
MIRT899983	hsa-miR-548s	CLIP-seq
MIRT899984	hsa-miR-582-5p	CLIP-seq
MIRT899985	hsa-miR-583	CLIP-seq
MIRT899986	hsa-miR-587	CLIP-seq
MIRT899987	hsa-miR-588	CLIP-seq
MIRT899988	hsa-miR-589	CLIP-seq
MIRT899989	hsa-miR-600	CLIP-seq
MIRT899990	hsa-miR-608	CLIP-seq
MIRT899991	hsa-miR-617	CLIP-seq
MIRT899992	hsa-miR-640	CLIP-seq
MIRT899993	hsa-miR-711	CLIP-seq
MIRT899994	hsa-miR-765	CLIP-seq
MIRT1966902	hsa-miR-1245b-3p	CLIP-seq
MIRT1966903	hsa-miR-1245b-5p	CLIP-seq
MIRT1966904	hsa-miR-1265	CLIP-seq
MIRT1966905	hsa-miR-1275	CLIP-seq
MIRT1966906	hsa-miR-1287	CLIP-seq
MIRT899926	hsa-miR-1915	CLIP-seq
MIRT1966907	hsa-miR-1972	CLIP-seq
MIRT1966908	hsa-miR-2392	CLIP-seq
MIRT1966909	hsa-miR-3135	CLIP-seq
MIRT1966910	hsa-miR-3142	CLIP-seq
MIRT1966911	hsa-miR-3151	CLIP-seq
MIRT1966912	hsa-miR-3156-3p	CLIP-seq
MIRT1966913	hsa-miR-3189-3p	CLIP-seq
MIRT1966914	hsa-miR-3199	CLIP-seq
MIRT1966915	hsa-miR-3616-5p	CLIP-seq
MIRT1966916	hsa-miR-3647-5p	CLIP-seq
MIRT1966917	hsa-miR-3650	CLIP-seq
MIRT1966918	hsa-miR-3689a-3p	CLIP-seq
MIRT1966919	hsa-miR-3689c	CLIP-seq
MIRT1966920	hsa-miR-4271	CLIP-seq
MIRT1966921	hsa-miR-4301	CLIP-seq
MIRT899951	hsa-miR-4303	CLIP-seq
MIRT899954	hsa-miR-4328	CLIP-seq
MIRT1966922	hsa-miR-4447	CLIP-seq
MIRT1966923	hsa-miR-4455	CLIP-seq
MIRT1966924	hsa-miR-4472	CLIP-seq
MIRT1966925	hsa-miR-4525	CLIP-seq
MIRT1966926	hsa-miR-4645-5p	CLIP-seq
MIRT1966927	hsa-miR-4665-5p	CLIP-seq
MIRT1966928	hsa-miR-4673	CLIP-seq
MIRT899969	hsa-miR-4682	CLIP-seq
MIRT1966929	hsa-miR-4723-5p	CLIP-seq
MIRT1966930	hsa-miR-4725-3p	CLIP-seq
MIRT899973	hsa-miR-4740-3p	CLIP-seq
MIRT1966931	hsa-miR-4742-5p	CLIP-seq
MIRT899975	hsa-miR-4755-3p	CLIP-seq
MIRT899976	hsa-miR-4761-5p	CLIP-seq
MIRT899980	hsa-miR-4785	CLIP-seq
MIRT1966932	hsa-miR-4795-5p	CLIP-seq
MIRT1966933	hsa-miR-491-5p	CLIP-seq
MIRT1966934	hsa-miR-519a	CLIP-seq
MIRT1966935	hsa-miR-519b-3p	CLIP-seq
MIRT1966936	hsa-miR-519c-3p	CLIP-seq
MIRT1966937	hsa-miR-532-3p	CLIP-seq
MIRT1966938	hsa-miR-573	CLIP-seq
MIRT899986	hsa-miR-587	CLIP-seq
MIRT1966939	hsa-miR-609	CLIP-seq
MIRT1966940	hsa-miR-625	CLIP-seq
MIRT2202678	hsa-miR-1243	CLIP-seq
MIRT899916	hsa-miR-1245	CLIP-seq
MIRT1966902	hsa-miR-1245b-3p	CLIP-seq
MIRT1966903	hsa-miR-1245b-5p	CLIP-seq
MIRT2202679	hsa-miR-1255a	CLIP-seq
MIRT2202680	hsa-miR-1255b	CLIP-seq
MIRT2202681	hsa-miR-125a-3p	CLIP-seq
MIRT1966905	hsa-miR-1275	CLIP-seq
MIRT899921	hsa-miR-129-5p	CLIP-seq
MIRT899922	hsa-miR-1297	CLIP-seq
MIRT2202682	hsa-miR-1302	CLIP-seq
MIRT899926	hsa-miR-1915	CLIP-seq
MIRT1966907	hsa-miR-1972	CLIP-seq
MIRT2202683	hsa-miR-2110	CLIP-seq
MIRT2202684	hsa-miR-2278	CLIP-seq
MIRT899929	hsa-miR-26a	CLIP-seq
MIRT899930	hsa-miR-26b	CLIP-seq
MIRT2202685	hsa-miR-299-3p	CLIP-seq
MIRT2202686	hsa-miR-31	CLIP-seq
MIRT2202687	hsa-miR-3122	CLIP-seq
MIRT1966910	hsa-miR-3142	CLIP-seq
MIRT2202688	hsa-miR-3147	CLIP-seq
MIRT2202689	hsa-miR-3150a-3p	CLIP-seq
MIRT1966911	hsa-miR-3151	CLIP-seq
MIRT2202690	hsa-miR-3180-5p	CLIP-seq
MIRT1966913	hsa-miR-3189-3p	CLIP-seq
MIRT2202691	hsa-miR-3194-3p	CLIP-seq
MIRT1966914	hsa-miR-3199	CLIP-seq
MIRT2202692	hsa-miR-326	CLIP-seq
MIRT2202693	hsa-miR-330-5p	CLIP-seq
MIRT2202694	hsa-miR-335	CLIP-seq
MIRT2202695	hsa-miR-3611	CLIP-seq
MIRT2202696	hsa-miR-3622a-3p	CLIP-seq
MIRT2202697	hsa-miR-3622b-3p	CLIP-seq
MIRT2202698	hsa-miR-3665	CLIP-seq
MIRT1966918	hsa-miR-3689a-3p	CLIP-seq
MIRT1966919	hsa-miR-3689c	CLIP-seq
MIRT2202699	hsa-miR-3913-5p	CLIP-seq
MIRT2202700	hsa-miR-3934	CLIP-seq
MIRT2202701	hsa-miR-3940-5p	CLIP-seq
MIRT2202702	hsa-miR-4255	CLIP-seq
MIRT1966920	hsa-miR-4271	CLIP-seq
MIRT2202703	hsa-miR-4298	CLIP-seq
MIRT2202704	hsa-miR-4425	CLIP-seq
MIRT1966922	hsa-miR-4447	CLIP-seq
MIRT899959	hsa-miR-4465	CLIP-seq
MIRT1966924	hsa-miR-4472	CLIP-seq
MIRT2202705	hsa-miR-4491	CLIP-seq
MIRT2202706	hsa-miR-4507	CLIP-seq
MIRT2202707	hsa-miR-4515	CLIP-seq
MIRT1966925	hsa-miR-4525	CLIP-seq
MIRT1966926	hsa-miR-4645-5p	CLIP-seq
MIRT2202708	hsa-miR-4648	CLIP-seq
MIRT2202709	hsa-miR-4654	CLIP-seq
MIRT2202710	hsa-miR-4657	CLIP-seq
MIRT1966927	hsa-miR-4665-5p	CLIP-seq
MIRT2202711	hsa-miR-4670-3p	CLIP-seq
MIRT1966928	hsa-miR-4673	CLIP-seq
MIRT899969	hsa-miR-4682	CLIP-seq
MIRT1966929	hsa-miR-4723-5p	CLIP-seq
MIRT1966930	hsa-miR-4725-3p	CLIP-seq
MIRT899972	hsa-miR-4728-5p	CLIP-seq
MIRT899973	hsa-miR-4740-3p	CLIP-seq
MIRT1966931	hsa-miR-4742-5p	CLIP-seq
MIRT899975	hsa-miR-4755-3p	CLIP-seq
MIRT2202712	hsa-miR-4757-5p	CLIP-seq
MIRT2202713	hsa-miR-4769-5p	CLIP-seq
MIRT1966933	hsa-miR-491-5p	CLIP-seq
MIRT1966939	hsa-miR-609	CLIP-seq
MIRT899991	hsa-miR-617	CLIP-seq
MIRT1966940	hsa-miR-625	CLIP-seq
MIRT899992	hsa-miR-640	CLIP-seq
MIRT2202714	hsa-miR-764	CLIP-seq
MIRT2202715	hsa-miR-943	CLIP-seq
MIRT899915	hsa-miR-1237	CLIP-seq
MIRT899921	hsa-miR-129-5p	CLIP-seq
MIRT2202684	hsa-miR-2278	CLIP-seq
MIRT1966914	hsa-miR-3199	CLIP-seq
MIRT899951	hsa-miR-4303	CLIP-seq
MIRT899926	hsa-miR-1915	CLIP-seq
MIRT899973	hsa-miR-4740-3p	CLIP-seq
MIRT2202678	hsa-miR-1243	CLIP-seq
MIRT2202679	hsa-miR-1255a	CLIP-seq
MIRT2202680	hsa-miR-1255b	CLIP-seq
MIRT2202682	hsa-miR-1302	CLIP-seq
MIRT899926	hsa-miR-1915	CLIP-seq
MIRT1966907	hsa-miR-1972	CLIP-seq
MIRT2202684	hsa-miR-2278	CLIP-seq
MIRT2202686	hsa-miR-31	CLIP-seq
MIRT2505650	hsa-miR-3117-5p	CLIP-seq
MIRT2202687	hsa-miR-3122	CLIP-seq
MIRT2202688	hsa-miR-3147	CLIP-seq
MIRT1966914	hsa-miR-3199	CLIP-seq
MIRT2202694	hsa-miR-335	CLIP-seq
MIRT2202695	hsa-miR-3611	CLIP-seq
MIRT2202698	hsa-miR-3665	CLIP-seq
MIRT2505651	hsa-miR-3685	CLIP-seq
MIRT2202699	hsa-miR-3913-5p	CLIP-seq
MIRT2202700	hsa-miR-3934	CLIP-seq
MIRT2202703	hsa-miR-4298	CLIP-seq
MIRT2505652	hsa-miR-4326	CLIP-seq
MIRT2202704	hsa-miR-4425	CLIP-seq
MIRT2202707	hsa-miR-4515	CLIP-seq
MIRT1966926	hsa-miR-4645-5p	CLIP-seq
MIRT2202711	hsa-miR-4670-3p	CLIP-seq
MIRT1966928	hsa-miR-4673	CLIP-seq
MIRT899973	hsa-miR-4740-3p	CLIP-seq
MIRT1966931	hsa-miR-4742-5p	CLIP-seq
MIRT2202715	hsa-miR-943	CLIP-seq
MIRT899926	hsa-miR-1915	CLIP-seq
MIRT899973	hsa-miR-4740-3p	CLIP-seq

Show/Hide all(8)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	28330616, 32296183
GO:0005886	Component	Plasma membrane	IBA	21873635
GO:0006810	Process	Transport	IBA	21873635
GO:0006811	Process	Ion transport	IEA
GO:0016021	Component	Integral component of membrane	IEA
GO:0022857	Function	Transmembrane transporter activity	IBA	21873635
GO:0043231	Component	Intracellular membrane-bounded organelle	IBA	21873635
GO:0055085	Process	Transmembrane transport	IEA

MIM	HGNC	e!Ensembl
607802	102	ENSG00000119946

Protein

UniProt ID

Q9NRU3

Protein name

Metal transporter CNNM1 (Ancient conserved domain-containing protein 1) (Cyclin-M1)

Protein function

Probable metal transporter.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01595	DUF21	227 → 414	Cyclin M transmembrane N-terminal domain	Domain
PF00571	CBS	498 → 562	CBS domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Restricted to brain and testis. {ECO:0000269|PubMed:12657465}.

Sequence

MAAAAAAAAAVGVRLRDCCSRGAVLLLFFSLSPRPPAAAAWLLGLRPEDTAGGRVSLEGG
TLRAAEGTSFLLRVYFQPGPPATAAPVPSPTLNSGENGTGDWAPRLVFIEEPPGGGGVAP
SAVPTRPPGPQRCREQSDWASDVEVLGPLRPGGVAGSALVQVRVRELRKGEAERGGAGGG
GKLFSLCAWDGRAWHHHGAAGGFLLRVRPRLYGPGGDLLPPAWLRALGALLLLALSALFS
GLRLSLLSLDPVELRVLRNSGSAAEQEQARRVQAVRGRGTHLLCTLLLGQAGANAALAGW
LYTSLPPGFGGTGEDYSEEGIHFPWLPALVCTGAVFLGAEICPYSVCSRHGLAIASHSVC
LTRLLMAAAFPVCYPLGRLLDWALRQEISTFYTREKLLETLRAADPYSDLVKEELNIIQG
ALELRTKVVEEVLTPLGDCFMLRSDAVLDFATVSEILRSGYTRIPVYEGDQRHNIVDILF
VKDLAFVDPDDCTPLLTVTRFYNRPLHCVFNDTRLDTVLEEFKKGKSHLAIVQRVNNEGE
GDPFYEVMGIVTLEDIIEEIIKSEILDETDLYTDNRKKQRVPQRERKRHDFSLFKLSDTE
MRVKISPQLLLATHRFMATEVEPFKSLYLSEKILLRLLKHPNVIQELKFDEKNKKAPEHY
LYQRNRPVDYFVLLLQGKVEVEVGKEGLRFENGAFTYYGVPAIMTTACSDNDVRKVGSLA
GSSVFLNRSPSRCSGLNRSESPNRERSDFGGSNTQLYSSSNNLYMPDYSVHILSDVQFVK
ITRQQYQNALTACHMDSSPQSPDMEAFTDGDSTKAPTTRGTPQTPKDDPAITLLNNRNSL
PCSRSDGLRSPSEVVYLRMEELAFTQEEMTDFEEHSTQQLTLSPAAVPTRAASDSECCNI
NLDTETSPCSSDFEENVGKKLLRTLSGQKRKRSPEGERTSEDNSNLTPLIT

Sequence length

951

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Melanoma	melanoma	rs121913315, rs121913323, rs137853080, rs137853081, rs121909232, rs121913388, rs104894094, rs104894095, rs104894097, rs104894098, rs104894099, rs104894109, rs137854599, rs11547328, rs104894340 View all (64 more)	16778180

Show/Hide Text Mining Associations (6)

Disease Name	Relationship Type	References
Associations from Text Mining
Diabetes Mellitus Type 2	Inhibit	25733456
Diabetes Mellitus Type 2	Associate	25733456
Epilepsy	Associate	37192718
Glioma	Associate	37192718
Infertility Male	Associate	36446526
Urofacial syndrome	Associate	15498024, 21393841

CNNM1 (cyclin and CBS domain divalent metal cation transport mediator 1)