IL1RAPL2 (interleukin 1 receptor accessory protein like 2)

Gene
Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
26280
Gene name Gene Name - the full gene name approved by the HGNC.
Interleukin 1 receptor accessory protein like 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
IL1RAPL2
Synonyms (NCBI Gene) Gene synonyms aliases
IL-1R9, IL1R9, IL1RAPL-2, TIGIRR-1
Chromosome Chromosome number
X
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
Xq22.3
Summary Summary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene is a member of the interleukin 1 receptor family. This protein is similar to the interleukin 1 accessory proteins, and is most closely related to interleukin 1 receptor accessory protein-like 1 (IL1RAPL1). This gene and IL
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Pathways
Show/Hide all(8)
miRTarBase ID miRNA Experiments Reference
MIRT2015301 hsa-miR-3125 CLIP-seq
MIRT2015302 hsa-miR-3916 CLIP-seq
MIRT2015303 hsa-miR-4257 CLIP-seq
MIRT2015301 hsa-miR-3125 CLIP-seq
MIRT2015302 hsa-miR-3916 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Pathways
Show/Hide all(20)
GO ID Ontology Definition Evidence Reference
GO:0004896 Function Cytokine receptor activity IEA
GO:0004908 Function Interleukin-1 receptor activity TAS 10757639
GO:0004910 Function Interleukin-1, type II, blocking receptor activity IEA
GO:0005886 Component Plasma membrane IBA
GO:0005886 Component Plasma membrane TAS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Pathways
MIM HGNC e!Ensembl
300277 5997 ENSG00000189108
Protein
Gene miRNA Gene ontology Other IDs Protein Pathways
UniProt ID Q9NP60
Protein name X-linked interleukin-1 receptor accessory protein-like 2 (IL-1 receptor accessory protein-like 2) (IL-1-RAPL-2) (IL-1RAPL-2) (IL1RAPL-2) (EC 3.2.2.6) (IL1RAPL-2-related protein) (Interleukin-1 receptor 9) (IL-1R-9) (IL-1R9) (Three immunoglobulin domain-co
PDB 7FD3 , 7SZL
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF18452 Ig_6 90 → 141 Immunoglobulin domain Domain
PF13895 Ig_2 143 → 231 Immunoglobulin domain Domain
PF00047 ig 249 → 345 Immunoglobulin domain Domain
PF01582 TIR 402 → 575 TIR domain Family
Tissue specificity TISSUE SPECIFICITY: Detected at low levels in fetal and adult brain, in particular in the frontal lobe, temporal lobe and cerebellum. Detected at very low levels in skin, liver, fetal ovary and in placenta. {ECO:0000269|PubMed:10882729, ECO:0000269|PubMed
Sequence 
MKPPFLLALVVCSVVSTNLKMVSKRNSVDGCIDWSVDLKTYMALAGEPVRVKCALFYSYI
RTNYSTAQSTGLRLMWYKNKGDLEEPIIFSEVRMSKEEDSIWFHSAEAQDSGFYTCVLRN
STYCMKVSMSLTVAENESGLCYNSRIRYLEKSEVTKRKEISCPDMDDFKKSDQEPDVVWY
KECKPKMWRSIIIQKGNALLIQEVQEEDGGNYTCELKYEGKLVRRTTELKVTALLTDKPP
KPLFPMENQPSVIDVQLGKPLNIPCKAFFGFSGESGPMIYWMKGEKFIEELAGHIREGEI
RLLKEHLGEKEVELALIFDSVVEADLANYTCHVENRNGRKHASVLLRKKDLIYKIELAGG
LGAIFLLLVLLVVIYKCYNIELMLFYRQHFGADETNDDNKEYDAYLSYTKVDQDTLDCDN
PEEEQFALEVLPDVLEKHYGYKLFIPERDLIPSGTYMEDLTRYVEQSRRLIIVLTPDYIL
RRGWSIFELESRLHNMLVSGEIKVILIECTELKGKVNCQEVESLKRSIKLLSLIKWKGSK
SSKLNSKFWKHLVYEMPIKKKEMLPRCHVLDSAEQGLFGELQPIPSIAMTSTSATLVSSQ
ADLPEFHPSDSMQIRHCCRGYKHEIPATTLPVPSLGNHHTYCNLPLTLLNGQLPLNNTLK
DTQEFHRNSSLLPLSSKELSFTSDIW
Sequence length 686
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Gene ontology Other IDs Protein Pathways
  Reactome
    Receptor-type tyrosine-protein phosphatases
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