AMD1 (adenosylmethionine decarboxylase 1)

Gene

• Entrez ID: 262
• Gene name: Adenosylmethionine decarboxylase 1
• Gene symbol: AMD1
• Synonyms (NCBI Gene): ADOMETDC, AMD, SAMDC
• Chromosome: 6
• Chromosome location: 6q21
• Summary: This gene encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Multiple alternatively sp

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT006862	hsa-miR-762	Luciferase reporter assay	22391449
MIRT006862	hsa-miR-762	Luciferase reporter assay	22391449
MIRT006862	hsa-miR-762	Luciferase reporter assay	22391449
MIRT021147	hsa-miR-186-5p	Sequencing	20371350
MIRT050922	hsa-miR-17-5p	CLASH	23622248
MIRT042921	hsa-miR-324-3p	CLASH	23622248
MIRT705759	hsa-miR-3927-3p	HITS-CLIP	23313552
MIRT705758	hsa-miR-6831-5p	HITS-CLIP	23313552
MIRT705757	hsa-miR-4459	HITS-CLIP	23313552
MIRT705756	hsa-miR-665	HITS-CLIP	23313552
MIRT705755	hsa-miR-6840-3p	HITS-CLIP	23313552
MIRT705754	hsa-let-7a-5p	HITS-CLIP	23313552
MIRT705753	hsa-let-7b-5p	HITS-CLIP	23313552
MIRT705752	hsa-let-7c-5p	HITS-CLIP	23313552
MIRT705751	hsa-let-7d-5p	HITS-CLIP	23313552
MIRT705750	hsa-let-7e-5p	HITS-CLIP	23313552
MIRT705749	hsa-let-7f-5p	HITS-CLIP	23313552
MIRT705748	hsa-let-7g-5p	HITS-CLIP	23313552
MIRT705747	hsa-let-7i-5p	HITS-CLIP	23313552
MIRT705746	hsa-miR-4458	HITS-CLIP	23313552
MIRT705745	hsa-miR-4500	HITS-CLIP	23313552
MIRT705744	hsa-miR-98-5p	HITS-CLIP	23313552
MIRT705743	hsa-miR-655-5p	HITS-CLIP	23313552
MIRT705742	hsa-miR-4451	HITS-CLIP	23313552
MIRT705741	hsa-miR-101-3p	HITS-CLIP	23313552
MIRT705740	hsa-miR-582-5p	HITS-CLIP	23313552
MIRT705738	hsa-miR-6807-5p	HITS-CLIP	23313552
MIRT705739	hsa-miR-1273e	HITS-CLIP	23313552
MIRT689050	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT689049	hsa-miR-3190-5p	HITS-CLIP	23313552
MIRT689048	hsa-miR-4738-3p	HITS-CLIP	23313552
MIRT689047	hsa-miR-6895-3p	HITS-CLIP	23313552
MIRT689046	hsa-miR-593-3p	HITS-CLIP	23313552
MIRT689045	hsa-miR-4684-5p	HITS-CLIP	23313552
MIRT689044	hsa-miR-6818-3p	HITS-CLIP	23313552
MIRT640899	hsa-miR-4494	HITS-CLIP	23824327
MIRT640898	hsa-miR-499b-5p	HITS-CLIP	23824327
MIRT640897	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT640896	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT640895	hsa-miR-5186	HITS-CLIP	23824327
MIRT640894	hsa-miR-8055	HITS-CLIP	23824327
MIRT524915	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT524914	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT524912	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT524913	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT524911	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT524910	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT524916	hsa-miR-576-3p	PAR-CLIP	23446348
MIRT524915	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT524914	hsa-miR-223-5p	PAR-CLIP	23446348
MIRT524912	hsa-miR-6867-5p	PAR-CLIP	23446348
MIRT524913	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT524911	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT524910	hsa-miR-574-5p	PAR-CLIP	23446348
MIRT508137	hsa-miR-132-3p	PAR-CLIP	23446348
MIRT508136	hsa-miR-212-3p	PAR-CLIP	23446348
MIRT508135	hsa-miR-4282	PAR-CLIP	23446348
MIRT508134	hsa-miR-4796-3p	PAR-CLIP	23446348
MIRT508133	hsa-miR-1243	PAR-CLIP	23446348
MIRT508132	hsa-miR-4773	PAR-CLIP	23446348
MIRT508131	hsa-miR-4495	PAR-CLIP	23446348
MIRT508130	hsa-miR-3128	PAR-CLIP	23446348
MIRT508129	hsa-miR-6868-5p	PAR-CLIP	23446348
MIRT508128	hsa-miR-4720-5p	PAR-CLIP	23446348
MIRT508127	hsa-miR-4799-3p	PAR-CLIP	23446348
MIRT508126	hsa-miR-5588-5p	PAR-CLIP	23446348
MIRT508125	hsa-miR-3689d	PAR-CLIP	23446348
MIRT508124	hsa-miR-6851-5p	PAR-CLIP	23446348
MIRT508123	hsa-miR-4764-5p	PAR-CLIP	23446348
MIRT508122	hsa-miR-885-3p	PAR-CLIP	23446348
MIRT508121	hsa-miR-7847-3p	PAR-CLIP	23446348
MIRT508120	hsa-miR-633	PAR-CLIP	23446348
MIRT508119	hsa-miR-518d-5p	PAR-CLIP	23446348
MIRT508118	hsa-miR-518e-5p	PAR-CLIP	23446348
MIRT508117	hsa-miR-518f-5p	PAR-CLIP	23446348
MIRT508116	hsa-miR-519a-5p	PAR-CLIP	23446348
MIRT508115	hsa-miR-519b-5p	PAR-CLIP	23446348
MIRT508114	hsa-miR-519c-5p	PAR-CLIP	23446348
MIRT508113	hsa-miR-520c-5p	PAR-CLIP	23446348
MIRT508112	hsa-miR-522-5p	PAR-CLIP	23446348
MIRT508111	hsa-miR-523-5p	PAR-CLIP	23446348
MIRT508110	hsa-miR-526a	PAR-CLIP	23446348
MIRT508109	hsa-miR-4777-5p	PAR-CLIP	23446348
MIRT482057	hsa-miR-551b-5p	PAR-CLIP	23592263
MIRT482055	hsa-miR-6753-5p	PAR-CLIP	23592263
MIRT482056	hsa-miR-6873-5p	PAR-CLIP	23592263
MIRT482054	hsa-miR-9500	PAR-CLIP	23592263
MIRT482053	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT482052	hsa-miR-4733-3p	PAR-CLIP	23592263
MIRT482051	hsa-miR-4270	PAR-CLIP	23592263
MIRT482050	hsa-miR-4441	PAR-CLIP	23592263
MIRT482049	hsa-miR-6754-5p	PAR-CLIP	23592263
MIRT482048	hsa-miR-7113-5p	PAR-CLIP	23592263
MIRT482047	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT482045	hsa-miR-8085	PAR-CLIP	23592263
MIRT689050	hsa-miR-6849-3p	PAR-CLIP	26701625
MIRT508133	hsa-miR-1243	PAR-CLIP	27292025
MIRT508137	hsa-miR-132-3p	PAR-CLIP	27292025
MIRT508136	hsa-miR-212-3p	PAR-CLIP	27292025
MIRT508130	hsa-miR-3128	PAR-CLIP	27292025
MIRT508125	hsa-miR-3689d	PAR-CLIP	27292025
MIRT508135	hsa-miR-4282	PAR-CLIP	27292025
MIRT508131	hsa-miR-4495	PAR-CLIP	27292025
MIRT508128	hsa-miR-4720-5p	PAR-CLIP	27292025
MIRT508123	hsa-miR-4764-5p	PAR-CLIP	27292025
MIRT508132	hsa-miR-4773	PAR-CLIP	27292025
MIRT508109	hsa-miR-4777-5p	PAR-CLIP	27292025
MIRT508134	hsa-miR-4796-3p	PAR-CLIP	27292025
MIRT508127	hsa-miR-4799-3p	PAR-CLIP	27292025
MIRT508119	hsa-miR-518d-5p	PAR-CLIP	27292025
MIRT508118	hsa-miR-518e-5p	PAR-CLIP	27292025
MIRT508117	hsa-miR-518f-5p	PAR-CLIP	27292025
MIRT508116	hsa-miR-519a-5p	PAR-CLIP	27292025
MIRT508115	hsa-miR-519b-5p	PAR-CLIP	27292025
MIRT508114	hsa-miR-519c-5p	PAR-CLIP	27292025
MIRT508113	hsa-miR-520c-5p	PAR-CLIP	27292025
MIRT508112	hsa-miR-522-5p	PAR-CLIP	27292025
MIRT508111	hsa-miR-523-5p	PAR-CLIP	27292025
MIRT508110	hsa-miR-526a	PAR-CLIP	27292025
MIRT508126	hsa-miR-5588-5p	PAR-CLIP	27292025
MIRT508120	hsa-miR-633	PAR-CLIP	27292025
MIRT508124	hsa-miR-6851-5p	PAR-CLIP	27292025
MIRT508129	hsa-miR-6868-5p	PAR-CLIP	27292025
MIRT482056	hsa-miR-6873-5p	PAR-CLIP	27292025
MIRT508121	hsa-miR-7847-3p	PAR-CLIP	27292025
MIRT508122	hsa-miR-885-3p	PAR-CLIP	27292025
MIRT705759	hsa-miR-3927-3p	HITS-CLIP	23313552
MIRT705758	hsa-miR-6831-5p	HITS-CLIP	23313552
MIRT705757	hsa-miR-4459	HITS-CLIP	23313552
MIRT705756	hsa-miR-665	HITS-CLIP	23313552
MIRT705755	hsa-miR-6840-3p	HITS-CLIP	23313552
MIRT705754	hsa-let-7a-5p	HITS-CLIP	23313552
MIRT705753	hsa-let-7b-5p	HITS-CLIP	23313552
MIRT705752	hsa-let-7c-5p	HITS-CLIP	23313552
MIRT705751	hsa-let-7d-5p	HITS-CLIP	23313552
MIRT705750	hsa-let-7e-5p	HITS-CLIP	23313552
MIRT705749	hsa-let-7f-5p	HITS-CLIP	23313552
MIRT705748	hsa-let-7g-5p	HITS-CLIP	23313552
MIRT705747	hsa-let-7i-5p	HITS-CLIP	23313552
MIRT705746	hsa-miR-4458	HITS-CLIP	23313552
MIRT705745	hsa-miR-4500	HITS-CLIP	23313552
MIRT705744	hsa-miR-98-5p	HITS-CLIP	23313552
MIRT705743	hsa-miR-655-5p	HITS-CLIP	23313552
MIRT705742	hsa-miR-4451	HITS-CLIP	23313552
MIRT705741	hsa-miR-101-3p	HITS-CLIP	23313552
MIRT705740	hsa-miR-582-5p	HITS-CLIP	23313552
MIRT705738	hsa-miR-6807-5p	HITS-CLIP	23313552
MIRT705739	hsa-miR-1273e	HITS-CLIP	23313552
MIRT689050	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT689049	hsa-miR-3190-5p	HITS-CLIP	23313552
MIRT689048	hsa-miR-4738-3p	HITS-CLIP	23313552
MIRT689047	hsa-miR-6895-3p	HITS-CLIP	23313552
MIRT689046	hsa-miR-593-3p	HITS-CLIP	23313552
MIRT689045	hsa-miR-4684-5p	HITS-CLIP	23313552
MIRT689044	hsa-miR-6818-3p	HITS-CLIP	23313552
MIRT640899	hsa-miR-4494	HITS-CLIP	23824327
MIRT640898	hsa-miR-499b-5p	HITS-CLIP	23824327
MIRT640897	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT640896	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT640895	hsa-miR-5186	HITS-CLIP	23824327
MIRT640894	hsa-miR-8055	HITS-CLIP	23824327
MIRT524915	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT524914	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT524912	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT524913	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT524911	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT524910	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT524916	hsa-miR-576-3p	PAR-CLIP	23446348
MIRT524915	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT524914	hsa-miR-223-5p	PAR-CLIP	23446348
MIRT524912	hsa-miR-6867-5p	PAR-CLIP	23446348
MIRT524913	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT524911	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT524910	hsa-miR-574-5p	PAR-CLIP	23446348
MIRT508137	hsa-miR-132-3p	PAR-CLIP	23446348
MIRT508136	hsa-miR-212-3p	PAR-CLIP	23446348
MIRT508135	hsa-miR-4282	PAR-CLIP	23446348
MIRT508134	hsa-miR-4796-3p	PAR-CLIP	23446348
MIRT508133	hsa-miR-1243	PAR-CLIP	23446348
MIRT508132	hsa-miR-4773	PAR-CLIP	23446348
MIRT508131	hsa-miR-4495	PAR-CLIP	23446348
MIRT508130	hsa-miR-3128	PAR-CLIP	23446348
MIRT508129	hsa-miR-6868-5p	PAR-CLIP	23446348
MIRT508128	hsa-miR-4720-5p	PAR-CLIP	23446348
MIRT508127	hsa-miR-4799-3p	PAR-CLIP	23446348
MIRT508126	hsa-miR-5588-5p	PAR-CLIP	23446348
MIRT508125	hsa-miR-3689d	PAR-CLIP	23446348
MIRT508124	hsa-miR-6851-5p	PAR-CLIP	23446348
MIRT508123	hsa-miR-4764-5p	PAR-CLIP	23446348
MIRT508122	hsa-miR-885-3p	PAR-CLIP	23446348
MIRT508121	hsa-miR-7847-3p	PAR-CLIP	23446348
MIRT508120	hsa-miR-633	PAR-CLIP	23446348
MIRT508119	hsa-miR-518d-5p	PAR-CLIP	23446348
MIRT508118	hsa-miR-518e-5p	PAR-CLIP	23446348
MIRT508117	hsa-miR-518f-5p	PAR-CLIP	23446348
MIRT508116	hsa-miR-519a-5p	PAR-CLIP	23446348
MIRT508115	hsa-miR-519b-5p	PAR-CLIP	23446348
MIRT508114	hsa-miR-519c-5p	PAR-CLIP	23446348
MIRT508113	hsa-miR-520c-5p	PAR-CLIP	23446348
MIRT508112	hsa-miR-522-5p	PAR-CLIP	23446348
MIRT508111	hsa-miR-523-5p	PAR-CLIP	23446348
MIRT508110	hsa-miR-526a	PAR-CLIP	23446348
MIRT508109	hsa-miR-4777-5p	PAR-CLIP	23446348
MIRT482057	hsa-miR-551b-5p	PAR-CLIP	23592263
MIRT482055	hsa-miR-6753-5p	PAR-CLIP	23592263
MIRT482056	hsa-miR-6873-5p	PAR-CLIP	23592263
MIRT482054	hsa-miR-9500	PAR-CLIP	23592263
MIRT482053	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT482052	hsa-miR-4733-3p	PAR-CLIP	23592263
MIRT482051	hsa-miR-4270	PAR-CLIP	23592263
MIRT482050	hsa-miR-4441	PAR-CLIP	23592263
MIRT482049	hsa-miR-6754-5p	PAR-CLIP	23592263
MIRT482048	hsa-miR-7113-5p	PAR-CLIP	23592263
MIRT482047	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT482045	hsa-miR-8085	PAR-CLIP	23592263
MIRT779614	hsa-miR-1245b-3p	CLIP-seq
MIRT779615	hsa-miR-1252	CLIP-seq
MIRT779616	hsa-miR-1255a	CLIP-seq
MIRT779617	hsa-miR-1255b	CLIP-seq
MIRT779618	hsa-miR-1257	CLIP-seq
MIRT779619	hsa-miR-1270	CLIP-seq
MIRT779620	hsa-miR-1273f	CLIP-seq
MIRT779621	hsa-miR-127-5p	CLIP-seq
MIRT779622	hsa-miR-1276	CLIP-seq
MIRT779623	hsa-miR-128	CLIP-seq
MIRT779624	hsa-miR-1323	CLIP-seq
MIRT779625	hsa-miR-183	CLIP-seq
MIRT779626	hsa-miR-186	CLIP-seq
MIRT779627	hsa-miR-18a	CLIP-seq
MIRT779628	hsa-miR-18b	CLIP-seq
MIRT779629	hsa-miR-217	CLIP-seq
MIRT779630	hsa-miR-224	CLIP-seq
MIRT779631	hsa-miR-2276	CLIP-seq
MIRT779632	hsa-miR-27a	CLIP-seq
MIRT779633	hsa-miR-27b	CLIP-seq
MIRT779634	hsa-miR-302f	CLIP-seq
MIRT779635	hsa-miR-3120-3p	CLIP-seq
MIRT779636	hsa-miR-3123	CLIP-seq
MIRT779637	hsa-miR-3125	CLIP-seq
MIRT779638	hsa-miR-3133	CLIP-seq
MIRT779639	hsa-miR-323-3p	CLIP-seq
MIRT779640	hsa-miR-338-5p	CLIP-seq
MIRT779641	hsa-miR-340	CLIP-seq
MIRT779642	hsa-miR-342-5p	CLIP-seq
MIRT779643	hsa-miR-3591-3p	CLIP-seq
MIRT779644	hsa-miR-3681	CLIP-seq
MIRT779645	hsa-miR-3682-3p	CLIP-seq
MIRT779646	hsa-miR-3688-3p	CLIP-seq
MIRT779647	hsa-miR-3916	CLIP-seq
MIRT779648	hsa-miR-3919	CLIP-seq
MIRT779649	hsa-miR-3928	CLIP-seq
MIRT779650	hsa-miR-3936	CLIP-seq
MIRT779651	hsa-miR-4261	CLIP-seq
MIRT779652	hsa-miR-4311	CLIP-seq
MIRT779653	hsa-miR-432	CLIP-seq
MIRT779654	hsa-miR-4428	CLIP-seq
MIRT779655	hsa-miR-4434	CLIP-seq
MIRT779656	hsa-miR-4446-5p	CLIP-seq
MIRT779657	hsa-miR-4475	CLIP-seq
MIRT779658	hsa-miR-4509	CLIP-seq
MIRT779659	hsa-miR-4516	CLIP-seq
MIRT779660	hsa-miR-451b	CLIP-seq
MIRT779661	hsa-miR-4531	CLIP-seq
MIRT779662	hsa-miR-4533	CLIP-seq
MIRT779663	hsa-miR-4635	CLIP-seq
MIRT779664	hsa-miR-4659a-5p	CLIP-seq
MIRT779665	hsa-miR-4659b-5p	CLIP-seq
MIRT779666	hsa-miR-4664-5p	CLIP-seq
MIRT779667	hsa-miR-4698	CLIP-seq
MIRT779668	hsa-miR-4704-3p	CLIP-seq
MIRT779669	hsa-miR-4711-5p	CLIP-seq
MIRT779670	hsa-miR-4717-3p	CLIP-seq
MIRT779671	hsa-miR-4735-3p	CLIP-seq
MIRT779672	hsa-miR-4753-3p	CLIP-seq
MIRT779673	hsa-miR-4755-5p	CLIP-seq
MIRT779674	hsa-miR-4760-5p	CLIP-seq
MIRT779675	hsa-miR-4768-5p	CLIP-seq
MIRT779676	hsa-miR-4772-3p	CLIP-seq
MIRT779677	hsa-miR-4793-5p	CLIP-seq
MIRT779678	hsa-miR-487a	CLIP-seq
MIRT779679	hsa-miR-488	CLIP-seq
MIRT779680	hsa-miR-490-5p	CLIP-seq
MIRT779681	hsa-miR-499-3p	CLIP-seq
MIRT779682	hsa-miR-499a-3p	CLIP-seq
MIRT779683	hsa-miR-513a-5p	CLIP-seq
MIRT779684	hsa-miR-539	CLIP-seq
MIRT779685	hsa-miR-548ae	CLIP-seq
MIRT779686	hsa-miR-548aj	CLIP-seq
MIRT779687	hsa-miR-548am	CLIP-seq
MIRT779688	hsa-miR-548m	CLIP-seq
MIRT779689	hsa-miR-548o	CLIP-seq
MIRT779690	hsa-miR-548x	CLIP-seq
MIRT779691	hsa-miR-579	CLIP-seq
MIRT779692	hsa-miR-604	CLIP-seq
MIRT779693	hsa-miR-620	CLIP-seq
MIRT779694	hsa-miR-640	CLIP-seq
MIRT779695	hsa-miR-642a	CLIP-seq
MIRT779696	hsa-miR-647	CLIP-seq
MIRT779697	hsa-miR-664	CLIP-seq
MIRT779698	hsa-miR-7	CLIP-seq
MIRT779699	hsa-miR-890	CLIP-seq
MIRT779700	hsa-miR-132	CLIP-seq
MIRT779701	hsa-miR-1909	CLIP-seq
MIRT779702	hsa-miR-212	CLIP-seq
MIRT779703	hsa-miR-323b-3p	CLIP-seq
MIRT779704	hsa-miR-3673	CLIP-seq
MIRT779705	hsa-miR-3923	CLIP-seq
MIRT779706	hsa-miR-409-3p	CLIP-seq
MIRT779663	hsa-miR-4635	CLIP-seq
MIRT779707	hsa-miR-4795-3p	CLIP-seq
MIRT779679	hsa-miR-488	CLIP-seq
MIRT779708	hsa-miR-496	CLIP-seq
MIRT779709	hsa-miR-548p	CLIP-seq
MIRT779710	hsa-miR-590-3p	CLIP-seq
MIRT779711	hsa-miR-656	CLIP-seq
MIRT1930078	hsa-miR-1179	CLIP-seq
MIRT779620	hsa-miR-1273f	CLIP-seq
MIRT1930079	hsa-miR-1279	CLIP-seq
MIRT779623	hsa-miR-128	CLIP-seq
MIRT1930080	hsa-miR-1285	CLIP-seq
MIRT1930081	hsa-miR-129-5p	CLIP-seq
MIRT1930082	hsa-miR-1305	CLIP-seq
MIRT779700	hsa-miR-132	CLIP-seq
MIRT779624	hsa-miR-1323	CLIP-seq
MIRT1930083	hsa-miR-193a-5p	CLIP-seq
MIRT779702	hsa-miR-212	CLIP-seq
MIRT1930084	hsa-miR-216a	CLIP-seq
MIRT1930085	hsa-miR-216b	CLIP-seq
MIRT779629	hsa-miR-217	CLIP-seq
MIRT779630	hsa-miR-224	CLIP-seq
MIRT779632	hsa-miR-27a	CLIP-seq
MIRT779633	hsa-miR-27b	CLIP-seq
MIRT1930086	hsa-miR-3148	CLIP-seq
MIRT1930087	hsa-miR-3160-5p	CLIP-seq
MIRT1930088	hsa-miR-3187-5p	CLIP-seq
MIRT1930089	hsa-miR-3617	CLIP-seq
MIRT779704	hsa-miR-3673	CLIP-seq
MIRT779646	hsa-miR-3688-3p	CLIP-seq
MIRT1930090	hsa-miR-378g	CLIP-seq
MIRT779705	hsa-miR-3923	CLIP-seq
MIRT1930091	hsa-miR-4305	CLIP-seq
MIRT1930092	hsa-miR-4314	CLIP-seq
MIRT779656	hsa-miR-4446-5p	CLIP-seq
MIRT1930093	hsa-miR-4486	CLIP-seq
MIRT1930094	hsa-miR-450a	CLIP-seq
MIRT1930095	hsa-miR-4536	CLIP-seq
MIRT1930096	hsa-miR-4659a-3p	CLIP-seq
MIRT1930097	hsa-miR-4659b-3p	CLIP-seq
MIRT1930098	hsa-miR-4699-3p	CLIP-seq
MIRT779669	hsa-miR-4711-5p	CLIP-seq
MIRT779670	hsa-miR-4717-3p	CLIP-seq
MIRT779672	hsa-miR-4753-3p	CLIP-seq
MIRT779673	hsa-miR-4755-5p	CLIP-seq
MIRT779707	hsa-miR-4795-3p	CLIP-seq
MIRT779678	hsa-miR-487a	CLIP-seq
MIRT779708	hsa-miR-496	CLIP-seq
MIRT779681	hsa-miR-499-3p	CLIP-seq
MIRT779682	hsa-miR-499a-3p	CLIP-seq
MIRT779689	hsa-miR-548o	CLIP-seq
MIRT779691	hsa-miR-579	CLIP-seq
MIRT779710	hsa-miR-590-3p	CLIP-seq
MIRT1930099	hsa-miR-612	CLIP-seq
MIRT1930100	hsa-miR-641	CLIP-seq
MIRT779695	hsa-miR-642a	CLIP-seq
MIRT779697	hsa-miR-664	CLIP-seq
MIRT1930101	hsa-miR-668	CLIP-seq
MIRT1930102	hsa-miR-670	CLIP-seq
MIRT779614	hsa-miR-1245b-3p	CLIP-seq
MIRT779620	hsa-miR-1273f	CLIP-seq
MIRT779623	hsa-miR-128	CLIP-seq
MIRT1930081	hsa-miR-129-5p	CLIP-seq
MIRT779700	hsa-miR-132	CLIP-seq
MIRT779624	hsa-miR-1323	CLIP-seq
MIRT2170889	hsa-miR-137	CLIP-seq
MIRT2170890	hsa-miR-1910	CLIP-seq
MIRT2170891	hsa-miR-1913	CLIP-seq
MIRT1930083	hsa-miR-193a-5p	CLIP-seq
MIRT2170892	hsa-miR-2117	CLIP-seq
MIRT779702	hsa-miR-212	CLIP-seq
MIRT1930085	hsa-miR-216b	CLIP-seq
MIRT779630	hsa-miR-224	CLIP-seq
MIRT779631	hsa-miR-2276	CLIP-seq
MIRT779632	hsa-miR-27a	CLIP-seq
MIRT779633	hsa-miR-27b	CLIP-seq
MIRT2170893	hsa-miR-3065-5p	CLIP-seq
MIRT779635	hsa-miR-3120-3p	CLIP-seq
MIRT779636	hsa-miR-3123	CLIP-seq
MIRT779637	hsa-miR-3125	CLIP-seq
MIRT2170894	hsa-miR-3146	CLIP-seq
MIRT1930086	hsa-miR-3148	CLIP-seq
MIRT2170895	hsa-miR-323-5p	CLIP-seq
MIRT2170896	hsa-miR-326	CLIP-seq
MIRT2170897	hsa-miR-330-5p	CLIP-seq
MIRT2170898	hsa-miR-338-3p	CLIP-seq
MIRT2170899	hsa-miR-361-3p	CLIP-seq
MIRT1930089	hsa-miR-3617	CLIP-seq
MIRT779646	hsa-miR-3688-3p	CLIP-seq
MIRT2170900	hsa-miR-3692	CLIP-seq
MIRT2170901	hsa-miR-371b-5p	CLIP-seq
MIRT779647	hsa-miR-3916	CLIP-seq
MIRT779648	hsa-miR-3919	CLIP-seq
MIRT779649	hsa-miR-3928	CLIP-seq
MIRT2170902	hsa-miR-3978	CLIP-seq
MIRT2170903	hsa-miR-410	CLIP-seq
MIRT779651	hsa-miR-4261	CLIP-seq
MIRT2170904	hsa-miR-4273	CLIP-seq
MIRT1930091	hsa-miR-4305	CLIP-seq
MIRT2170905	hsa-miR-4313	CLIP-seq
MIRT2170906	hsa-miR-4422	CLIP-seq
MIRT779656	hsa-miR-4446-5p	CLIP-seq
MIRT779657	hsa-miR-4475	CLIP-seq
MIRT1930094	hsa-miR-450a	CLIP-seq
MIRT779660	hsa-miR-451b	CLIP-seq
MIRT1930096	hsa-miR-4659a-3p	CLIP-seq
MIRT779664	hsa-miR-4659a-5p	CLIP-seq
MIRT1930097	hsa-miR-4659b-3p	CLIP-seq
MIRT779665	hsa-miR-4659b-5p	CLIP-seq
MIRT2170907	hsa-miR-4666-5p	CLIP-seq
MIRT2170908	hsa-miR-4672	CLIP-seq
MIRT779668	hsa-miR-4704-3p	CLIP-seq
MIRT779669	hsa-miR-4711-5p	CLIP-seq
MIRT779672	hsa-miR-4753-3p	CLIP-seq
MIRT779673	hsa-miR-4755-5p	CLIP-seq
MIRT2170909	hsa-miR-4762-5p	CLIP-seq
MIRT779676	hsa-miR-4772-3p	CLIP-seq
MIRT779677	hsa-miR-4793-5p	CLIP-seq
MIRT779679	hsa-miR-488	CLIP-seq
MIRT2170910	hsa-miR-505	CLIP-seq
MIRT779683	hsa-miR-513a-5p	CLIP-seq
MIRT2170911	hsa-miR-544	CLIP-seq
MIRT779688	hsa-miR-548m	CLIP-seq
MIRT779689	hsa-miR-548o	CLIP-seq
MIRT779691	hsa-miR-579	CLIP-seq
MIRT2170912	hsa-miR-607	CLIP-seq
MIRT1930100	hsa-miR-641	CLIP-seq
MIRT779695	hsa-miR-642a	CLIP-seq
MIRT779697	hsa-miR-664	CLIP-seq
MIRT1930102	hsa-miR-670	CLIP-seq
MIRT2170913	hsa-miR-876-3p	CLIP-seq
MIRT2170914	hsa-miR-891b	CLIP-seq
MIRT779621	hsa-miR-127-5p	CLIP-seq
MIRT1930082	hsa-miR-1305	CLIP-seq
MIRT779624	hsa-miR-1323	CLIP-seq
MIRT779643	hsa-miR-3591-3p	CLIP-seq
MIRT1930091	hsa-miR-4305	CLIP-seq
MIRT779656	hsa-miR-4446-5p	CLIP-seq
MIRT1930095	hsa-miR-4536	CLIP-seq
MIRT779673	hsa-miR-4755-5p	CLIP-seq
MIRT779674	hsa-miR-4760-5p	CLIP-seq
MIRT779678	hsa-miR-487a	CLIP-seq
MIRT779689	hsa-miR-548o	CLIP-seq
MIRT2473488	hsa-miR-570	CLIP-seq
MIRT779695	hsa-miR-642a	CLIP-seq
MIRT1930101	hsa-miR-668	CLIP-seq
MIRT779621	hsa-miR-127-5p	CLIP-seq
MIRT1930082	hsa-miR-1305	CLIP-seq
MIRT779624	hsa-miR-1323	CLIP-seq
MIRT779643	hsa-miR-3591-3p	CLIP-seq
MIRT1930091	hsa-miR-4305	CLIP-seq
MIRT779656	hsa-miR-4446-5p	CLIP-seq
MIRT1930095	hsa-miR-4536	CLIP-seq
MIRT779673	hsa-miR-4755-5p	CLIP-seq
MIRT779674	hsa-miR-4760-5p	CLIP-seq
MIRT779678	hsa-miR-487a	CLIP-seq
MIRT779689	hsa-miR-548o	CLIP-seq
MIRT2473488	hsa-miR-570	CLIP-seq
MIRT779695	hsa-miR-642a	CLIP-seq
MIRT1930101	hsa-miR-668	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004014	Function	Adenosylmethionine decarboxylase activity	IBA
GO:0004014	Function	Adenosylmethionine decarboxylase activity	IEA
GO:0004014	Function	Adenosylmethionine decarboxylase activity	TAS	1917972, 2460457
GO:0005515	Function	Protein binding	IPI	28514442, 32296183, 33961781
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	TAS
GO:0006595	Process	Polyamine metabolic process	TAS
GO:0006596	Process	Polyamine biosynthetic process	IEA
GO:0006597	Process	Spermine biosynthetic process	IBA
GO:0006597	Process	Spermine biosynthetic process	IEA
GO:0008295	Process	Spermidine biosynthetic process	IBA
GO:0008295	Process	Spermidine biosynthetic process	IEA
GO:0016829	Function	Lyase activity	IEA
GO:0016831	Function	Carboxy-lyase activity	IEA
GO:0019810	Function	Putrescine binding	IBA
GO:0042802	Function	Identical protein binding	IPI	32296183

Other IDs

• MIM: 180980
• HGNC: 457
• e!Ensembl: ENSG00000123505

Protein

• UniProt ID: P17707
• Protein name: S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain]
• Protein function: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.
• PDB: 1I72, 1I79, 1I7B, 1I7C, 1I7M, 1JEN, 1JL0, 1MSV, 3DZ2, 3DZ3, 3DZ4, 3DZ5, 3DZ6, 3DZ7, 3EP3, 3EP4, 3EP5, 3EP6, 3EP7, 3EP8, 3EP9, 3EPA, 3EPB, 3H0V, 3H0W
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01536	SAM_decarbox	4 → 326	Adenosylmethionine decarboxylase	Family

• Sequence:

  MEAAHFFEGTEKLLEVWFSRQQPDANQGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQ
  EAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKP
  SHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDFPESRVISQPDQTLEIL
  MSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATMFNPCGYSMNGMKSDGTYW
  TIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLASPQ
  KIEGFKRLDCQSAMFNDYNFVFTSFAKKQQQQQS

• Sequence length: 334

Pathways

KEGG:

Cysteine and methionine metabolism
Arginine and proline metabolism
Metabolic pathways

Reactome:

Metabolism of polyamines

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
DEVELOPMENTAL AND EPILEPTIC ENCEPHALOPATHY 87	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LYMPHOID LEUKEMIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Relationship Type	References	Evidence Score
Cap Myopathy	Associate	18974881	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Associate	38025761	★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Associate	35812454	★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Associate	27433286	★☆☆☆☆ Found in Text Mining only
Inflammation	Associate	26558825, 27433286	★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Associate	30097719	★☆☆☆☆ Found in Text Mining only
Neoplasms	Inhibit	17558447	★☆☆☆☆ Found in Text Mining only
Neoplasms	Associate	20215859, 27433286	★☆☆☆☆ Found in Text Mining only
Neoplasms Adipose Tissue	Associate	22496743	★☆☆☆☆ Found in Text Mining only
Obesity	Associate	22496743, 26558825	★☆☆☆☆ Found in Text Mining only
Pre Eclampsia	Associate	25528892	★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Associate	20215859	★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Stimulate	30397274	★☆☆☆☆ Found in Text Mining only
Purpura Thrombocytopenic Idiopathic	Associate	37291547	★☆☆☆☆ Found in Text Mining only